Incidental Mutation 'R0831:Umodl1'
| ID |
77584 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Umodl1
|
| Ensembl Gene |
ENSMUSG00000054134 |
| Gene Name |
uromodulin-like 1 |
| Synonyms |
D17Ertd488e |
| MMRRC Submission |
039010-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0831 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
31173614-31229684 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 31215325 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Histidine
at position 1050
(Y1050H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000110202
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066554]
[ENSMUST00000066981]
[ENSMUST00000114555]
|
| AlphaFold |
Q5DID3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066554
AA Change: Y1050H
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000067443
Gene: ENSMUSG00000054134
AA Change: Y1050H
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000066981
AA Change: Y935H
|
| SMART Domains |
Protein: ENSMUSP00000065470
Gene: ENSMUSG00000054134
AA Change: Y935H
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
8.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
8.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
619 |
632 |
N/A |
INTRINSIC |
|
SEA
|
706 |
821 |
8.88e-2 |
SMART |
|
EGF
|
818 |
859 |
4.26e0 |
SMART |
|
ZP
|
909 |
1152 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1186 |
1208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000114555
AA Change: Y1050H
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000110202
Gene: ENSMUSG00000054134
AA Change: Y1050H
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
9.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
9.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.2280 |
| Coding Region Coverage |
- 1x: 99.6%
- 3x: 98.9%
- 10x: 96.9%
- 20x: 92.0%
|
| Validation Efficiency |
95% (82/86) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2900092C05Rik |
C |
T |
7: 12,284,523 (GRCm39) |
|
probably benign |
Het |
| 3425401B19Rik |
T |
C |
14: 32,384,228 (GRCm39) |
N579S |
probably benign |
Het |
| Adck1 |
G |
T |
12: 88,335,118 (GRCm39) |
M1I |
probably null |
Het |
| Adgra3 |
A |
T |
5: 50,128,144 (GRCm39) |
I779N |
probably damaging |
Het |
| Adgrf2 |
A |
G |
17: 43,021,334 (GRCm39) |
S497P |
probably damaging |
Het |
| Afg3l2 |
A |
C |
18: 67,554,297 (GRCm39) |
F468L |
probably damaging |
Het |
| Alms1 |
T |
A |
6: 85,605,502 (GRCm39) |
I2384N |
probably benign |
Het |
| Ankrd13b |
A |
T |
11: 77,363,585 (GRCm39) |
S244R |
probably damaging |
Het |
| Aox1 |
T |
A |
1: 58,378,842 (GRCm39) |
H1030Q |
probably benign |
Het |
| Ap1b1 |
A |
G |
11: 4,973,092 (GRCm39) |
|
probably benign |
Het |
| Atxn2l |
A |
G |
7: 126,098,332 (GRCm39) |
S187P |
probably damaging |
Het |
| B4galt4 |
G |
T |
16: 38,588,341 (GRCm39) |
E57D |
probably benign |
Het |
| Cad |
T |
C |
5: 31,224,944 (GRCm39) |
V949A |
probably damaging |
Het |
| Cadps2 |
C |
T |
6: 23,321,739 (GRCm39) |
S1051N |
possibly damaging |
Het |
| Ccdc66 |
C |
T |
14: 27,219,313 (GRCm39) |
V148I |
probably benign |
Het |
| Ccser1 |
C |
T |
6: 61,400,045 (GRCm39) |
P55S |
probably damaging |
Het |
| Cds2 |
T |
C |
2: 132,127,887 (GRCm39) |
|
probably null |
Het |
| Cep95 |
A |
G |
11: 106,705,530 (GRCm39) |
D548G |
probably benign |
Het |
| Chil3 |
A |
G |
3: 106,057,063 (GRCm39) |
Y294H |
probably benign |
Het |
| Chmp5 |
A |
G |
4: 40,949,500 (GRCm39) |
D39G |
probably damaging |
Het |
| Chrd |
T |
A |
16: 20,560,059 (GRCm39) |
F887I |
probably damaging |
Het |
| Col24a1 |
G |
T |
3: 145,034,520 (GRCm39) |
G580V |
probably damaging |
Het |
| Col6a2 |
A |
T |
10: 76,439,939 (GRCm39) |
N655K |
probably damaging |
Het |
| Ctsf |
A |
T |
19: 4,909,868 (GRCm39) |
Y416F |
possibly damaging |
Het |
| Dennd5a |
A |
C |
7: 109,533,961 (GRCm39) |
V77G |
probably damaging |
Het |
| Dna2 |
A |
T |
10: 62,795,108 (GRCm39) |
K460* |
probably null |
Het |
| Dnah17 |
A |
T |
11: 117,951,097 (GRCm39) |
M2842K |
probably damaging |
Het |
| Dnajc13 |
C |
A |
9: 104,049,811 (GRCm39) |
G1765V |
probably damaging |
Het |
| Donson |
A |
C |
16: 91,480,651 (GRCm39) |
C243W |
probably damaging |
Het |
| Dpp8 |
A |
T |
9: 64,985,961 (GRCm39) |
N817I |
possibly damaging |
Het |
| Eef1d |
G |
A |
15: 75,768,655 (GRCm39) |
|
probably benign |
Het |
| Esf1 |
T |
A |
2: 140,010,279 (GRCm39) |
D19V |
probably damaging |
Het |
| Gm21738 |
T |
A |
14: 19,415,957 (GRCm38) |
Y194F |
probably benign |
Het |
| Gm21738 |
T |
C |
14: 19,415,963 (GRCm38) |
K192R |
probably benign |
Het |
| Gm9867 |
C |
A |
4: 140,049,799 (GRCm39) |
A128S |
unknown |
Het |
| Igsf23 |
G |
T |
7: 19,675,662 (GRCm39) |
|
probably benign |
Het |
| Inhca |
T |
C |
9: 103,146,978 (GRCm39) |
H292R |
possibly damaging |
Het |
| Kdm7a |
C |
A |
6: 39,143,699 (GRCm39) |
|
probably benign |
Het |
| Kif14 |
G |
A |
1: 136,453,609 (GRCm39) |
|
probably benign |
Het |
| Mroh7 |
T |
C |
4: 106,537,990 (GRCm39) |
N1229D |
possibly damaging |
Het |
| Mrps11 |
C |
A |
7: 78,441,611 (GRCm39) |
|
probably benign |
Het |
| Mtmr2 |
T |
A |
9: 13,707,409 (GRCm39) |
D248E |
probably damaging |
Het |
| Myrfl |
C |
A |
10: 116,619,114 (GRCm39) |
S748I |
probably benign |
Het |
| Nop14 |
T |
C |
5: 34,807,864 (GRCm39) |
E366G |
possibly damaging |
Het |
| Or13c3 |
T |
G |
4: 52,855,764 (GRCm39) |
I250L |
possibly damaging |
Het |
| Or2w25 |
C |
T |
11: 59,504,480 (GRCm39) |
T230I |
possibly damaging |
Het |
| Or52z13 |
A |
G |
7: 103,247,338 (GRCm39) |
I272V |
probably benign |
Het |
| Or7e177 |
T |
A |
9: 20,211,861 (GRCm39) |
C123S |
probably benign |
Het |
| Or8g2b |
C |
T |
9: 39,751,579 (GRCm39) |
P283L |
probably damaging |
Het |
| Phykpl |
G |
T |
11: 51,476,366 (GRCm39) |
E29* |
probably null |
Het |
| Plppr4 |
A |
G |
3: 117,125,295 (GRCm39) |
|
probably null |
Het |
| Prmt2 |
A |
C |
10: 76,043,641 (GRCm39) |
|
probably benign |
Het |
| Prodh2 |
T |
A |
7: 30,193,649 (GRCm39) |
Y114* |
probably null |
Het |
| Prr23a2 |
C |
A |
9: 98,738,917 (GRCm39) |
H92N |
probably damaging |
Het |
| Rasl10b |
G |
A |
11: 83,308,665 (GRCm39) |
|
probably null |
Het |
| Rdx |
C |
A |
9: 51,977,117 (GRCm39) |
A122E |
probably damaging |
Het |
| Rspo3 |
T |
G |
10: 29,330,253 (GRCm39) |
D236A |
unknown |
Het |
| Sdk2 |
A |
T |
11: 113,723,084 (GRCm39) |
D1302E |
probably damaging |
Het |
| Sipa1 |
A |
T |
19: 5,710,382 (GRCm39) |
D209E |
probably damaging |
Het |
| Sirpa |
T |
G |
2: 129,469,856 (GRCm39) |
|
probably benign |
Het |
| Ska1 |
A |
C |
18: 74,330,570 (GRCm39) |
|
probably benign |
Het |
| Slc4a9 |
T |
C |
18: 36,668,331 (GRCm39) |
|
probably benign |
Het |
| Slco1b2 |
T |
C |
6: 141,631,172 (GRCm39) |
V602A |
probably benign |
Het |
| Slco2a1 |
T |
C |
9: 102,959,533 (GRCm39) |
V543A |
probably damaging |
Het |
| Sorcs3 |
A |
T |
19: 48,682,433 (GRCm39) |
L489F |
probably damaging |
Het |
| Sorl1 |
T |
C |
9: 41,982,365 (GRCm39) |
|
probably benign |
Het |
| Sp140l1 |
C |
G |
1: 85,077,226 (GRCm39) |
K113N |
probably benign |
Het |
| Spindoc |
G |
T |
19: 7,352,100 (GRCm39) |
N82K |
probably benign |
Het |
| Stk17b |
C |
A |
1: 53,796,651 (GRCm39) |
C372F |
probably damaging |
Het |
| Tbck |
A |
G |
3: 132,428,052 (GRCm39) |
|
probably benign |
Het |
| Thoc1 |
C |
T |
18: 9,963,267 (GRCm39) |
T127I |
probably benign |
Het |
| Togaram2 |
G |
T |
17: 72,023,439 (GRCm39) |
R765L |
probably damaging |
Het |
| Tprg1 |
A |
G |
16: 25,136,219 (GRCm39) |
Y70C |
probably damaging |
Het |
| Ugcg |
C |
T |
4: 59,207,798 (GRCm39) |
P46S |
probably benign |
Het |
| Vmn1r205 |
T |
A |
13: 22,776,586 (GRCm39) |
D172V |
probably benign |
Het |
| Vmn1r79 |
A |
T |
7: 11,910,990 (GRCm39) |
N291Y |
probably damaging |
Het |
| Vmn2r112 |
T |
A |
17: 22,833,980 (GRCm39) |
N549K |
probably damaging |
Het |
| Vrk3 |
T |
A |
7: 44,414,227 (GRCm39) |
L241Q |
probably damaging |
Het |
| Zc3h7a |
A |
G |
16: 10,969,744 (GRCm39) |
S386P |
probably damaging |
Het |
|
| Other mutations in Umodl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00915:Umodl1
|
APN |
17 |
31,227,724 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01344:Umodl1
|
APN |
17 |
31,215,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01529:Umodl1
|
APN |
17 |
31,215,233 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01609:Umodl1
|
APN |
17 |
31,217,800 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01625:Umodl1
|
APN |
17 |
31,215,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01877:Umodl1
|
APN |
17 |
31,201,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01977:Umodl1
|
APN |
17 |
31,192,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02063:Umodl1
|
APN |
17 |
31,206,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02160:Umodl1
|
APN |
17 |
31,205,091 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02252:Umodl1
|
APN |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02427:Umodl1
|
APN |
17 |
31,187,415 (GRCm39) |
splice site |
probably benign |
|
|
IGL02496:Umodl1
|
APN |
17 |
31,217,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02633:Umodl1
|
APN |
17 |
31,208,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03271:Umodl1
|
APN |
17 |
31,205,473 (GRCm39) |
nonsense |
probably null |
|
|
IGL03392:Umodl1
|
APN |
17 |
31,215,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Disquieting
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
floored
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7231_umodl1_507
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
surprising
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
unsettling
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
G1citation:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
PIT4468001:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0653:Umodl1
|
UTSW |
17 |
31,203,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1078:Umodl1
|
UTSW |
17 |
31,178,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1166:Umodl1
|
UTSW |
17 |
31,221,772 (GRCm39) |
splice site |
probably benign |
|
|
R1231:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1459:Umodl1
|
UTSW |
17 |
31,205,478 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1459:Umodl1
|
UTSW |
17 |
31,201,232 (GRCm39) |
splice site |
probably benign |
|
|
R1510:Umodl1
|
UTSW |
17 |
31,178,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1654:Umodl1
|
UTSW |
17 |
31,206,942 (GRCm39) |
missense |
probably benign |
|
|
R1757:Umodl1
|
UTSW |
17 |
31,227,674 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1781:Umodl1
|
UTSW |
17 |
31,187,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1873:Umodl1
|
UTSW |
17 |
31,201,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1911:Umodl1
|
UTSW |
17 |
31,211,128 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R1917:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1918:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2057:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2058:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2089:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2431:Umodl1
|
UTSW |
17 |
31,211,062 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2903:Umodl1
|
UTSW |
17 |
31,211,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3032:Umodl1
|
UTSW |
17 |
31,208,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3956:Umodl1
|
UTSW |
17 |
31,221,837 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3975:Umodl1
|
UTSW |
17 |
31,203,763 (GRCm39) |
nonsense |
probably null |
|
|
R4207:Umodl1
|
UTSW |
17 |
31,178,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4287:Umodl1
|
UTSW |
17 |
31,207,039 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4452:Umodl1
|
UTSW |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4684:Umodl1
|
UTSW |
17 |
31,217,088 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4769:Umodl1
|
UTSW |
17 |
31,202,976 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4887:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4888:Umodl1
|
UTSW |
17 |
31,218,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4978:Umodl1
|
UTSW |
17 |
31,205,055 (GRCm39) |
missense |
probably benign |
|
|
R4993:Umodl1
|
UTSW |
17 |
31,205,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5241:Umodl1
|
UTSW |
17 |
31,203,066 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5254:Umodl1
|
UTSW |
17 |
31,199,333 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5454:Umodl1
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5456:Umodl1
|
UTSW |
17 |
31,201,263 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5754:Umodl1
|
UTSW |
17 |
31,213,761 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6189:Umodl1
|
UTSW |
17 |
31,215,256 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6222:Umodl1
|
UTSW |
17 |
31,221,866 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6289:Umodl1
|
UTSW |
17 |
31,201,325 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6432:Umodl1
|
UTSW |
17 |
31,205,121 (GRCm39) |
missense |
probably benign |
0.38 |
|
R6478:Umodl1
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6702:Umodl1
|
UTSW |
17 |
31,205,273 (GRCm39) |
splice site |
probably null |
|
|
R6822:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
R6999:Umodl1
|
UTSW |
17 |
31,218,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7067:Umodl1
|
UTSW |
17 |
31,201,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7123:Umodl1
|
UTSW |
17 |
31,201,318 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7219:Umodl1
|
UTSW |
17 |
31,201,236 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7231:Umodl1
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7234:Umodl1
|
UTSW |
17 |
31,205,595 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7297:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7392:Umodl1
|
UTSW |
17 |
31,201,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7401:Umodl1
|
UTSW |
17 |
31,217,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7461:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7594:Umodl1
|
UTSW |
17 |
31,173,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7613:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7763:Umodl1
|
UTSW |
17 |
31,205,430 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7797:Umodl1
|
UTSW |
17 |
31,178,125 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7832:Umodl1
|
UTSW |
17 |
31,192,666 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7954:Umodl1
|
UTSW |
17 |
31,205,361 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8088:Umodl1
|
UTSW |
17 |
31,192,770 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8111:Umodl1
|
UTSW |
17 |
31,190,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8314:Umodl1
|
UTSW |
17 |
31,203,806 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8826:Umodl1
|
UTSW |
17 |
31,202,958 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9067:Umodl1
|
UTSW |
17 |
31,192,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9091:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9099:Umodl1
|
UTSW |
17 |
31,178,147 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9270:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9341:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9343:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9400:Umodl1
|
UTSW |
17 |
31,215,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9569:Umodl1
|
UTSW |
17 |
31,217,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9615:Umodl1
|
UTSW |
17 |
31,217,152 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9787:Umodl1
|
UTSW |
17 |
31,178,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GAGCCTTTGTCTCCTTGGAACCTG -3'
(R):5'- TGAATAAGAGCCTTCCTGGTCTCCC -3'
Sequencing Primer
(F):5'- TGACCCTTCTGGCAACATGAC -3'
(R):5'- GTCTCCCTACCAGGTGCAAAC -3'
|
| Posted On |
2013-10-16 |
Incidental Mutation