Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01382:Vmn2r93'

78883

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r93

Ensembl Gene

ENSMUSG00000079698

Gene Name

vomeronasal 2, receptor 93

Synonyms

EG627132

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.084) question?

Stock #

IGL01382

Quality Score

Status

Chromosome

Chromosomal Location

18518543-18546703 bp(+) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

T to A at 18533578 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Stop codon at position 494 (L494*)

Ref Sequence

ENSEMBL: ENSMUSP00000155900 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000079206] [ENSMUST00000231879] [ENSMUST00000231938]

AlphaFold

L7N1Z9

Predicted Effect

probably null
Transcript: ENSMUST00000079206
AA Change: L494*

SMART Domains

Protein: ENSMUSP00000078200
Gene: ENSMUSG00000079698
AA Change: L494*

Domain	Start	End	E-Value	Type
signal peptide	1	19	N/A	INTRINSIC
Pfam:ANF_receptor	82	453	5.9e-40	PFAM
Pfam:NCD3G	509	562	2.6e-21	PFAM
Pfam:7tm_3	594	830	1.5e-50	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000231879
AA Change: L494*

Predicted Effect

probably null
Transcript: ENSMUST00000231938
AA Change: L494*

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 39 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ap5z1	G	T	5: 142,458,006 (GRCm39)	R393L	probably benign	Het
Arhgap21	G	T	2: 20,860,511 (GRCm39)	P1128T	probably damaging	Het
Atp12a	T	G	14: 56,617,412 (GRCm39)	C567W	probably damaging	Het
Bcat2	C	A	7: 45,237,684 (GRCm39)	R312S	probably damaging	Het
Cacna1g	T	A	11: 94,356,684 (GRCm39)	T151S	probably damaging	Het
Chid1	G	A	7: 141,110,166 (GRCm39)	T53M	probably damaging	Het
Dis3l2	A	G	1: 86,784,925 (GRCm39)	D272G	probably benign	Het
Entrep3	T	C	3: 89,095,733 (GRCm39)	S596P	probably damaging	Het
Ephx4	A	G	5: 107,577,585 (GRCm39)	E303G	probably damaging	Het
Fsd1	C	T	17: 56,303,733 (GRCm39)	S491F	probably damaging	Het
Gm9843	A	T	16: 76,200,460 (GRCm39)		noncoding transcript	Het
Gnb1l	T	C	16: 18,362,950 (GRCm39)	F11S	probably damaging	Het
Ipmk	C	T	10: 71,212,596 (GRCm39)	T186M	probably damaging	Het
Jph1	T	C	1: 17,086,380 (GRCm39)	T381A	probably damaging	Het
Kbtbd8	T	A	6: 95,099,211 (GRCm39)	I163K	probably damaging	Het
Kif18a	T	A	2: 109,127,111 (GRCm39)	Y348*	probably null	Het
Lrrc37a	T	A	11: 103,389,581 (GRCm39)	D1948V	probably damaging	Het
Mc4r	A	G	18: 66,992,864 (GRCm39)	I83T	probably damaging	Het
Myh8	A	T	11: 67,192,799 (GRCm39)	E1530V	probably damaging	Het
Naip6	C	T	13: 100,436,364 (GRCm39)	E720K	possibly damaging	Het
Ncor2	T	A	5: 125,132,837 (GRCm39)	Q50L	probably damaging	Het
Or5p70	G	A	7: 107,994,452 (GRCm39)	V42M	probably benign	Het
Or9s15	A	G	1: 92,524,922 (GRCm39)	Y227C	possibly damaging	Het
Plxnd1	A	T	6: 115,937,488 (GRCm39)	M1575K	probably damaging	Het
Ptprg	T	G	14: 12,237,797 (GRCm38)	M643R	probably benign	Het
Reck	T	A	4: 43,940,662 (GRCm39)	C824S	probably damaging	Het
Rpgrip1	C	T	14: 52,382,934 (GRCm39)	T689I	possibly damaging	Het
Ruvbl2	A	T	7: 45,072,161 (GRCm39)	S358T	probably benign	Het
Sec14l3	G	T	11: 4,018,104 (GRCm39)	C128F	probably damaging	Het
Serpinf2	C	T	11: 75,328,863 (GRCm39)		probably benign	Het
Sez6l	C	T	5: 112,573,487 (GRCm39)	V842I	probably benign	Het
Tm6sf2	A	G	8: 70,531,018 (GRCm39)	Y257C	probably damaging	Het
Tmpo	T	C	10: 91,001,912 (GRCm39)	D99G	probably damaging	Het
Tulp3	A	C	6: 128,302,033 (GRCm39)	N329K	probably damaging	Het
Vmn1r7	T	A	6: 57,001,708 (GRCm39)	D184V	probably damaging	Het
Vmn2r24	A	G	6: 123,763,938 (GRCm39)	T272A	possibly damaging	Het
Wdr18	T	C	10: 79,801,106 (GRCm39)	L173P	probably damaging	Het
Zfp663	T	A	2: 165,200,935 (GRCm39)	Y33F	probably damaging	Het
Zmiz2	T	A	11: 6,353,781 (GRCm39)		probably null	Het

Other mutations in Vmn2r93

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00743:Vmn2r93	APN	17	18,546,504 (GRCm39)	missense	probably damaging	1.00
IGL01326:Vmn2r93	APN	17	18,536,906 (GRCm39)	missense	possibly damaging	0.92
IGL01328:Vmn2r93	APN	17	18,545,819 (GRCm39)	missense	probably benign	0.00
IGL01360:Vmn2r93	APN	17	18,525,510 (GRCm39)	missense	possibly damaging	0.71
IGL01463:Vmn2r93	APN	17	18,525,150 (GRCm39)	missense	probably damaging	1.00
IGL02057:Vmn2r93	APN	17	18,546,032 (GRCm39)	missense	probably damaging	1.00
IGL02257:Vmn2r93	APN	17	18,545,770 (GRCm39)	unclassified	probably benign
IGL02686:Vmn2r93	APN	17	18,533,526 (GRCm39)	missense	possibly damaging	0.89
IGL02720:Vmn2r93	APN	17	18,525,296 (GRCm39)	missense	probably damaging	1.00
IGL03328:Vmn2r93	APN	17	18,525,220 (GRCm39)	missense	probably damaging	1.00
PIT4576001:Vmn2r93	UTSW	17	18,533,473 (GRCm39)	missense	probably benign
R0067:Vmn2r93	UTSW	17	18,546,672 (GRCm39)	missense	probably benign	0.00
R0067:Vmn2r93	UTSW	17	18,546,672 (GRCm39)	missense	probably benign	0.00
R0240:Vmn2r93	UTSW	17	18,525,061 (GRCm39)	missense	probably benign	0.00
R0240:Vmn2r93	UTSW	17	18,525,061 (GRCm39)	missense	probably benign	0.00
R0488:Vmn2r93	UTSW	17	18,546,311 (GRCm39)	missense	probably damaging	1.00
R0667:Vmn2r93	UTSW	17	18,546,503 (GRCm39)	missense	probably damaging	1.00
R0668:Vmn2r93	UTSW	17	18,518,667 (GRCm39)	missense	probably benign	0.00
R0850:Vmn2r93	UTSW	17	18,525,279 (GRCm39)	missense	possibly damaging	0.93
R0924:Vmn2r93	UTSW	17	18,524,443 (GRCm39)	missense	probably benign
R0947:Vmn2r93	UTSW	17	18,524,343 (GRCm39)	missense	probably benign	0.06
R1124:Vmn2r93	UTSW	17	18,518,710 (GRCm39)	missense	probably benign	0.00
R1584:Vmn2r93	UTSW	17	18,525,413 (GRCm39)	missense	possibly damaging	0.84
R1943:Vmn2r93	UTSW	17	18,546,063 (GRCm39)	missense	probably benign	0.04
R2012:Vmn2r93	UTSW	17	18,536,840 (GRCm39)	missense	probably benign	0.01
R2018:Vmn2r93	UTSW	17	18,546,324 (GRCm39)	missense	probably damaging	1.00
R2196:Vmn2r93	UTSW	17	18,525,428 (GRCm39)	missense	probably damaging	1.00
R2373:Vmn2r93	UTSW	17	18,518,665 (GRCm39)	missense	probably benign
R2864:Vmn2r93	UTSW	17	18,546,323 (GRCm39)	missense	probably damaging	1.00
R4276:Vmn2r93	UTSW	17	18,525,092 (GRCm39)	missense	possibly damaging	0.47
R4446:Vmn2r93	UTSW	17	18,524,312 (GRCm39)	missense	possibly damaging	0.93
R4537:Vmn2r93	UTSW	17	18,525,194 (GRCm39)	missense	possibly damaging	0.86
R4674:Vmn2r93	UTSW	17	18,525,255 (GRCm39)	missense	probably benign	0.34
R4726:Vmn2r93	UTSW	17	18,536,960 (GRCm39)	missense	probably damaging	1.00
R4936:Vmn2r93	UTSW	17	18,524,327 (GRCm39)	missense	possibly damaging	0.95
R4984:Vmn2r93	UTSW	17	18,533,389 (GRCm39)	splice site	probably null
R5111:Vmn2r93	UTSW	17	18,546,326 (GRCm39)	missense	probably damaging	0.99
R5749:Vmn2r93	UTSW	17	18,518,546 (GRCm39)	missense	probably benign	0.06
R5918:Vmn2r93	UTSW	17	18,546,030 (GRCm39)	missense	probably damaging	1.00
R5921:Vmn2r93	UTSW	17	18,546,030 (GRCm39)	missense	probably damaging	1.00
R6091:Vmn2r93	UTSW	17	18,545,958 (GRCm39)	missense	probably benign	0.06
R6283:Vmn2r93	UTSW	17	18,524,366 (GRCm39)	missense	probably benign	0.02
R6680:Vmn2r93	UTSW	17	18,536,920 (GRCm39)	nonsense	probably null
R6876:Vmn2r93	UTSW	17	18,525,450 (GRCm39)	missense	probably benign	0.00
R6963:Vmn2r93	UTSW	17	18,536,849 (GRCm39)	missense	probably damaging	1.00
R6996:Vmn2r93	UTSW	17	18,524,903 (GRCm39)	missense	probably damaging	1.00
R7027:Vmn2r93	UTSW	17	18,533,548 (GRCm39)	missense	probably benign	0.01
R7034:Vmn2r93	UTSW	17	18,546,672 (GRCm39)	missense	probably benign	0.00
R7036:Vmn2r93	UTSW	17	18,546,672 (GRCm39)	missense	probably benign	0.00
R7246:Vmn2r93	UTSW	17	18,546,012 (GRCm39)	missense	possibly damaging	0.89
R7258:Vmn2r93	UTSW	17	18,525,403 (GRCm39)	missense	probably benign	0.32
R7323:Vmn2r93	UTSW	17	18,533,497 (GRCm39)	nonsense	probably null
R7325:Vmn2r93	UTSW	17	18,524,249 (GRCm39)	missense	probably benign	0.01
R7390:Vmn2r93	UTSW	17	18,525,329 (GRCm39)	missense	probably damaging	1.00
R7427:Vmn2r93	UTSW	17	18,546,672 (GRCm39)	missense	probably benign	0.00
R7428:Vmn2r93	UTSW	17	18,546,672 (GRCm39)	missense	probably benign	0.00
R7448:Vmn2r93	UTSW	17	18,546,248 (GRCm39)	missense	probably benign	0.19
R7453:Vmn2r93	UTSW	17	18,533,580 (GRCm39)	missense	probably benign	0.10
R7562:Vmn2r93	UTSW	17	18,518,731 (GRCm39)	missense	probably benign	0.01
R7662:Vmn2r93	UTSW	17	18,525,631 (GRCm39)	missense	probably benign	0.00
R7682:Vmn2r93	UTSW	17	18,525,583 (GRCm39)	missense	probably benign	0.03
R7704:Vmn2r93	UTSW	17	18,536,910 (GRCm39)	missense	probably benign	0.01
R7772:Vmn2r93	UTSW	17	18,533,482 (GRCm39)	missense	probably damaging	0.99
R7957:Vmn2r93	UTSW	17	18,545,954 (GRCm39)	nonsense	probably null
R8276:Vmn2r93	UTSW	17	18,525,649 (GRCm39)	critical splice donor site	probably null
R8290:Vmn2r93	UTSW	17	18,524,291 (GRCm39)	missense	probably damaging	1.00
R8362:Vmn2r93	UTSW	17	18,546,353 (GRCm39)	missense	probably benign	0.02
R8376:Vmn2r93	UTSW	17	18,525,230 (GRCm39)	missense	probably damaging	1.00
R8870:Vmn2r93	UTSW	17	18,525,320 (GRCm39)	missense	possibly damaging	0.91
R8925:Vmn2r93	UTSW	17	18,546,500 (GRCm39)	missense	probably damaging	0.99
R8927:Vmn2r93	UTSW	17	18,546,500 (GRCm39)	missense	probably damaging	0.99
R8954:Vmn2r93	UTSW	17	18,546,252 (GRCm39)	missense	probably damaging	0.99
R9038:Vmn2r93	UTSW	17	18,524,471 (GRCm39)	missense	probably benign
R9131:Vmn2r93	UTSW	17	18,546,143 (GRCm39)	missense	probably damaging	0.99
R9205:Vmn2r93	UTSW	17	18,524,281 (GRCm39)	missense	probably damaging	1.00
R9530:Vmn2r93	UTSW	17	18,518,562 (GRCm39)	missense	probably damaging	0.96
Z1088:Vmn2r93	UTSW	17	18,546,665 (GRCm39)	missense	probably damaging	1.00
Z1177:Vmn2r93	UTSW	17	18,525,600 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-11-05