Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01382:Vmn1r7'

78886

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r7

Ensembl Gene

ENSMUSG00000093696

Gene Name

vomeronasal 1 receptor 7

Synonyms

V1rc31, Gm5568

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.121) question?

Stock #

IGL01382

Quality Score

Status

Chromosome

Chromosomal Location

57001323-57002258 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 57001708 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Valine at position 184 (D184V)

Ref Sequence

ENSEMBL: ENSMUSP00000135571 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000176252]

AlphaFold

E9Q8T0

Predicted Effect

probably damaging
Transcript: ENSMUST00000176252
AA Change: D184V

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000135571
Gene: ENSMUSG00000093696
AA Change: D184V

Domain	Start	End	E-Value	Type
Pfam:V1R	28	293	1.1e-59	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 39 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ap5z1	G	T	5: 142,458,006 (GRCm39)	R393L	probably benign	Het
Arhgap21	G	T	2: 20,860,511 (GRCm39)	P1128T	probably damaging	Het
Atp12a	T	G	14: 56,617,412 (GRCm39)	C567W	probably damaging	Het
Bcat2	C	A	7: 45,237,684 (GRCm39)	R312S	probably damaging	Het
Cacna1g	T	A	11: 94,356,684 (GRCm39)	T151S	probably damaging	Het
Chid1	G	A	7: 141,110,166 (GRCm39)	T53M	probably damaging	Het
Dis3l2	A	G	1: 86,784,925 (GRCm39)	D272G	probably benign	Het
Entrep3	T	C	3: 89,095,733 (GRCm39)	S596P	probably damaging	Het
Ephx4	A	G	5: 107,577,585 (GRCm39)	E303G	probably damaging	Het
Fsd1	C	T	17: 56,303,733 (GRCm39)	S491F	probably damaging	Het
Gm9843	A	T	16: 76,200,460 (GRCm39)		noncoding transcript	Het
Gnb1l	T	C	16: 18,362,950 (GRCm39)	F11S	probably damaging	Het
Ipmk	C	T	10: 71,212,596 (GRCm39)	T186M	probably damaging	Het
Jph1	T	C	1: 17,086,380 (GRCm39)	T381A	probably damaging	Het
Kbtbd8	T	A	6: 95,099,211 (GRCm39)	I163K	probably damaging	Het
Kif18a	T	A	2: 109,127,111 (GRCm39)	Y348*	probably null	Het
Lrrc37a	T	A	11: 103,389,581 (GRCm39)	D1948V	probably damaging	Het
Mc4r	A	G	18: 66,992,864 (GRCm39)	I83T	probably damaging	Het
Myh8	A	T	11: 67,192,799 (GRCm39)	E1530V	probably damaging	Het
Naip6	C	T	13: 100,436,364 (GRCm39)	E720K	possibly damaging	Het
Ncor2	T	A	5: 125,132,837 (GRCm39)	Q50L	probably damaging	Het
Or5p70	G	A	7: 107,994,452 (GRCm39)	V42M	probably benign	Het
Or9s15	A	G	1: 92,524,922 (GRCm39)	Y227C	possibly damaging	Het
Plxnd1	A	T	6: 115,937,488 (GRCm39)	M1575K	probably damaging	Het
Ptprg	T	G	14: 12,237,797 (GRCm38)	M643R	probably benign	Het
Reck	T	A	4: 43,940,662 (GRCm39)	C824S	probably damaging	Het
Rpgrip1	C	T	14: 52,382,934 (GRCm39)	T689I	possibly damaging	Het
Ruvbl2	A	T	7: 45,072,161 (GRCm39)	S358T	probably benign	Het
Sec14l3	G	T	11: 4,018,104 (GRCm39)	C128F	probably damaging	Het
Serpinf2	C	T	11: 75,328,863 (GRCm39)		probably benign	Het
Sez6l	C	T	5: 112,573,487 (GRCm39)	V842I	probably benign	Het
Tm6sf2	A	G	8: 70,531,018 (GRCm39)	Y257C	probably damaging	Het
Tmpo	T	C	10: 91,001,912 (GRCm39)	D99G	probably damaging	Het
Tulp3	A	C	6: 128,302,033 (GRCm39)	N329K	probably damaging	Het
Vmn2r24	A	G	6: 123,763,938 (GRCm39)	T272A	possibly damaging	Het
Vmn2r93	T	A	17: 18,533,578 (GRCm39)	L494*	probably null	Het
Wdr18	T	C	10: 79,801,106 (GRCm39)	L173P	probably damaging	Het
Zfp663	T	A	2: 165,200,935 (GRCm39)	Y33F	probably damaging	Het
Zmiz2	T	A	11: 6,353,781 (GRCm39)		probably null	Het

Other mutations in Vmn1r7

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01528:Vmn1r7	APN	6	57,001,532 (GRCm39)	missense	probably benign
IGL02024:Vmn1r7	APN	6	57,001,874 (GRCm39)	missense	probably benign	0.01
IGL02234:Vmn1r7	APN	6	57,001,537 (GRCm39)	missense	probably damaging	0.98
IGL02610:Vmn1r7	APN	6	57,002,037 (GRCm39)	missense	probably benign	0.01
IGL02691:Vmn1r7	APN	6	57,001,373 (GRCm39)	missense	probably benign	0.05
R0529:Vmn1r7	UTSW	6	57,001,450 (GRCm39)	missense	possibly damaging	0.78
R0548:Vmn1r7	UTSW	6	57,002,066 (GRCm39)	missense	probably damaging	0.96
R1254:Vmn1r7	UTSW	6	57,001,772 (GRCm39)	missense	probably damaging	1.00
R1279:Vmn1r7	UTSW	6	57,001,934 (GRCm39)	missense	possibly damaging	0.63
R1582:Vmn1r7	UTSW	6	57,002,143 (GRCm39)	missense	probably damaging	1.00
R1973:Vmn1r7	UTSW	6	57,002,011 (GRCm39)	missense	probably benign	0.00
R1991:Vmn1r7	UTSW	6	57,001,853 (GRCm39)	missense	probably benign	0.37
R2160:Vmn1r7	UTSW	6	57,001,879 (GRCm39)	missense	probably damaging	0.97
R3546:Vmn1r7	UTSW	6	57,001,834 (GRCm39)	missense	possibly damaging	0.80
R3547:Vmn1r7	UTSW	6	57,001,834 (GRCm39)	missense	possibly damaging	0.80
R5901:Vmn1r7	UTSW	6	57,001,591 (GRCm39)	missense	probably damaging	1.00
R6294:Vmn1r7	UTSW	6	57,001,404 (GRCm39)	missense	probably benign	0.00
R7063:Vmn1r7	UTSW	6	57,001,418 (GRCm39)	missense	possibly damaging	0.63
R7192:Vmn1r7	UTSW	6	57,001,452 (GRCm39)	missense	probably benign	0.00
R7647:Vmn1r7	UTSW	6	57,002,255 (GRCm39)	missense	probably benign	0.01
R7781:Vmn1r7	UTSW	6	57,001,553 (GRCm39)	missense	probably benign	0.03
R9457:Vmn1r7	UTSW	6	57,001,508 (GRCm39)	missense	probably damaging	0.97

Posted On

2013-11-05