Incidental Mutation 'IGL01383:Psg26'
| ID |
78932 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Psg26
|
| Ensembl Gene |
ENSMUSG00000070799 |
| Gene Name |
pregnancy-specific beta-1-glycoprotein 26 |
| Synonyms |
EG574429, cea14 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.048)
|
| Stock # |
IGL01383
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
18208507-18218102 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 18214179 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 161
(V161A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000092392
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094798]
|
| AlphaFold |
Q4KL65 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000094798
AA Change: V161A
PolyPhen 2
Score 0.900 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000092392
Gene: ENSMUSG00000070799
AA Change: V161A
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
40 |
141 |
4.93e-3 |
SMART |
|
IG
|
160 |
261 |
2.39e-1 |
SMART |
|
IG
|
280 |
379 |
6.07e-3 |
SMART |
|
IGc2
|
397 |
461 |
5.48e-10 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 41 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930555G01Rik |
C |
A |
14: 5,051,570 (GRCm38) |
|
probably null |
Het |
| Abca9 |
A |
C |
11: 110,004,119 (GRCm39) |
|
probably benign |
Het |
| Aox1 |
T |
A |
1: 58,333,464 (GRCm39) |
M227K |
probably benign |
Het |
| Asb5 |
T |
A |
8: 55,003,544 (GRCm39) |
L22H |
probably damaging |
Het |
| Atrx |
T |
C |
X: 104,845,681 (GRCm39) |
D2309G |
probably damaging |
Het |
| Cand1 |
T |
A |
10: 119,044,072 (GRCm39) |
T1074S |
probably damaging |
Het |
| Cep97 |
T |
C |
16: 55,731,970 (GRCm39) |
E534G |
probably damaging |
Het |
| Cftr |
C |
A |
6: 18,226,040 (GRCm39) |
N329K |
probably benign |
Het |
| Clec7a |
T |
C |
6: 129,449,603 (GRCm39) |
T16A |
probably damaging |
Het |
| Col1a1 |
G |
A |
11: 94,836,351 (GRCm39) |
R674H |
probably damaging |
Het |
| Csf2rb2 |
T |
C |
15: 78,181,243 (GRCm39) |
S50G |
possibly damaging |
Het |
| Eepd1 |
A |
G |
9: 25,393,778 (GRCm39) |
D14G |
probably damaging |
Het |
| Fsd1 |
C |
T |
17: 56,303,733 (GRCm39) |
S491F |
probably damaging |
Het |
| Grin1 |
C |
A |
2: 25,186,979 (GRCm39) |
R694L |
possibly damaging |
Het |
| Gtf3c1 |
A |
G |
7: 125,298,672 (GRCm39) |
I151T |
probably damaging |
Het |
| Havcr2 |
T |
C |
11: 46,360,375 (GRCm39) |
S152P |
probably damaging |
Het |
| Hvcn1 |
T |
C |
5: 122,375,766 (GRCm39) |
V15A |
probably damaging |
Het |
| Iqca1l |
A |
T |
5: 24,753,292 (GRCm39) |
N453K |
probably benign |
Het |
| Map3k10 |
C |
T |
7: 27,357,424 (GRCm39) |
V785M |
probably benign |
Het |
| Mis18bp1 |
T |
C |
12: 65,195,763 (GRCm39) |
N667S |
probably benign |
Het |
| Mup3 |
A |
C |
4: 62,004,196 (GRCm39) |
Y106D |
probably damaging |
Het |
| Mypn |
G |
T |
10: 62,971,576 (GRCm39) |
N821K |
probably damaging |
Het |
| Odad1 |
T |
C |
7: 45,589,124 (GRCm39) |
S179P |
probably damaging |
Het |
| Or2y1c |
T |
A |
11: 49,361,880 (GRCm39) |
W301R |
probably benign |
Het |
| Or52b4 |
A |
G |
7: 102,184,140 (GRCm39) |
Y62C |
probably benign |
Het |
| Or5ac25 |
A |
T |
16: 59,182,316 (GRCm39) |
N88K |
probably benign |
Het |
| Or5i1 |
A |
G |
2: 87,613,217 (GRCm39) |
D111G |
possibly damaging |
Het |
| Pcdhb10 |
A |
T |
18: 37,546,328 (GRCm39) |
H468L |
probably benign |
Het |
| Pramel27 |
T |
G |
4: 143,573,102 (GRCm39) |
|
probably benign |
Het |
| Prp2 |
C |
A |
6: 132,576,841 (GRCm39) |
P43T |
unknown |
Het |
| Rab17 |
T |
G |
1: 90,887,815 (GRCm39) |
D115A |
probably damaging |
Het |
| Rrp1b |
T |
C |
17: 32,277,552 (GRCm39) |
F611L |
probably damaging |
Het |
| Skor1 |
T |
A |
9: 63,053,838 (GRCm39) |
T44S |
probably benign |
Het |
| Spaca5 |
T |
C |
X: 20,934,725 (GRCm39) |
|
probably benign |
Het |
| Tatdn3 |
G |
A |
1: 190,787,578 (GRCm39) |
|
probably benign |
Het |
| Tbk1 |
T |
C |
10: 121,412,184 (GRCm39) |
D118G |
probably damaging |
Het |
| Tnfsf13b |
T |
C |
8: 10,081,528 (GRCm39) |
F230S |
probably damaging |
Het |
| Tnrc6c |
T |
C |
11: 117,605,083 (GRCm39) |
S73P |
probably benign |
Het |
| Vmn2r109 |
A |
G |
17: 20,761,383 (GRCm39) |
V658A |
possibly damaging |
Het |
| Vmn2r116 |
C |
T |
17: 23,620,575 (GRCm39) |
L770F |
probably damaging |
Het |
| Wwp2 |
T |
A |
8: 108,259,923 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Psg26 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01010:Psg26
|
APN |
7 |
18,212,255 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
IGL01453:Psg26
|
APN |
7 |
18,213,999 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01603:Psg26
|
APN |
7 |
18,209,028 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02201:Psg26
|
APN |
7 |
18,214,071 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02468:Psg26
|
APN |
7 |
18,212,387 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02648:Psg26
|
APN |
7 |
18,216,691 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02812:Psg26
|
APN |
7 |
18,209,080 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0226:Psg26
|
UTSW |
7 |
18,217,883 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0352:Psg26
|
UTSW |
7 |
18,209,181 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0369:Psg26
|
UTSW |
7 |
18,216,481 (GRCm39) |
nonsense |
probably null |
|
|
R0718:Psg26
|
UTSW |
7 |
18,212,212 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0718:Psg26
|
UTSW |
7 |
18,209,160 (GRCm39) |
missense |
probably benign |
0.23 |
|
R1710:Psg26
|
UTSW |
7 |
18,213,966 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1899:Psg26
|
UTSW |
7 |
18,212,350 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1958:Psg26
|
UTSW |
7 |
18,212,264 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2102:Psg26
|
UTSW |
7 |
18,209,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3766:Psg26
|
UTSW |
7 |
18,208,996 (GRCm39) |
missense |
probably benign |
|
|
R4544:Psg26
|
UTSW |
7 |
18,212,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4977:Psg26
|
UTSW |
7 |
18,209,235 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5000:Psg26
|
UTSW |
7 |
18,214,057 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5376:Psg26
|
UTSW |
7 |
18,214,030 (GRCm39) |
missense |
probably benign |
|
|
R5416:Psg26
|
UTSW |
7 |
18,216,525 (GRCm39) |
missense |
probably benign |
|
|
R5435:Psg26
|
UTSW |
7 |
18,212,398 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6000:Psg26
|
UTSW |
7 |
18,216,617 (GRCm39) |
nonsense |
probably null |
|
|
R6285:Psg26
|
UTSW |
7 |
18,216,753 (GRCm39) |
missense |
probably benign |
|
|
R7062:Psg26
|
UTSW |
7 |
18,216,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7083:Psg26
|
UTSW |
7 |
18,213,934 (GRCm39) |
nonsense |
probably null |
|
|
R7513:Psg26
|
UTSW |
7 |
18,209,225 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7817:Psg26
|
UTSW |
7 |
18,216,572 (GRCm39) |
missense |
not run |
|
|
R7857:Psg26
|
UTSW |
7 |
18,212,215 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7905:Psg26
|
UTSW |
7 |
18,209,242 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8047:Psg26
|
UTSW |
7 |
18,212,474 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8789:Psg26
|
UTSW |
7 |
18,216,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8877:Psg26
|
UTSW |
7 |
18,217,865 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9012:Psg26
|
UTSW |
7 |
18,216,596 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9203:Psg26
|
UTSW |
7 |
18,212,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9327:Psg26
|
UTSW |
7 |
18,216,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9547:Psg26
|
UTSW |
7 |
18,214,087 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Psg26
|
UTSW |
7 |
18,214,216 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Posted On |
2013-11-05 |
Incidental Mutation