Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01392:Gvin-ps3'

79250

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gvin-ps3

Ensembl Gene

ENSMUSG00000095649

Gene Name

GTPase, very large interferon inducible, pseudogene 3

Synonyms

Gm8979, Gm21884

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.133) question?

Stock #

IGL01392

Quality Score

Status

Chromosome

Chromosomal Location

105674938-105678355 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 105682962 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Valine at position 98 (I98V)

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000176647

Predicted Effect

probably benign
Transcript: ENSMUST00000180034
AA Change: I98V

PolyPhen 2 Score 0.007 (Sensitivity: 0.96; Specificity: 0.75)

SMART Domains

Protein: ENSMUSP00000137556
Gene: ENSMUSG00000095649
AA Change: I98V

Domain	Start	End	E-Value	Type
low complexity region	104	116	N/A	INTRINSIC
low complexity region	414	425	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000183386

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 32 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acvr1	A	G	2: 58,390,558 (GRCm39)	V2A	probably benign	Het
Adgrf5	A	T	17: 43,760,903 (GRCm39)	Q866L	probably benign	Het
Ankrd13a	A	G	5: 114,935,914 (GRCm39)	E295G	probably benign	Het
Arid1a	T	C	4: 133,408,348 (GRCm39)	D2053G	unknown	Het
Calr4	A	G	4: 109,111,071 (GRCm39)	E272G	probably benign	Het
Cmya5	T	C	13: 93,225,714 (GRCm39)	S3125G	probably damaging	Het
Dnah7b	T	C	1: 46,165,948 (GRCm39)	Y538H	probably damaging	Het
Eri3	T	C	4: 117,446,356 (GRCm39)		probably null	Het
Fmo6	T	A	1: 162,757,580 (GRCm39)	R63*	probably null	Het
Gm7168	G	A	17: 14,169,169 (GRCm39)	D179N	probably benign	Het
Got1l1	T	C	8: 27,688,019 (GRCm39)	T337A	probably damaging	Het
Igf2r	A	G	17: 12,923,236 (GRCm39)	M1191T	probably benign	Het
Ighv1-54	A	G	12: 115,157,557 (GRCm39)	L30P	probably damaging	Het
Igkv8-30	A	G	6: 70,094,331 (GRCm39)	S27P	probably benign	Het
Kcnab2	A	T	4: 152,478,254 (GRCm39)	V335E	possibly damaging	Het
Klf12	A	T	14: 100,387,193 (GRCm39)	I3N	probably damaging	Het
Megf8	T	C	7: 25,063,174 (GRCm39)	V2510A	probably benign	Het
Mme	A	G	3: 63,269,467 (GRCm39)	D592G	probably damaging	Het
Myh1	A	G	11: 67,112,127 (GRCm39)	N1727S	probably benign	Het
Ncor1	A	G	11: 62,231,420 (GRCm39)	S796P	probably damaging	Het
Nlrp14	A	G	7: 106,797,120 (GRCm39)		probably benign	Het
Or51f23	T	A	7: 102,453,061 (GRCm39)	Y125*	probably null	Het
Or5b95	T	A	19: 12,658,167 (GRCm39)	Y232N	probably benign	Het
Or5p80	C	T	7: 108,229,885 (GRCm39)	R229C	probably benign	Het
Plekhm2	A	G	4: 141,369,737 (GRCm39)	V86A	probably damaging	Het
Popdc2	G	T	16: 38,194,493 (GRCm39)	V305L	probably benign	Het
Prb1b	T	C	6: 132,289,383 (GRCm39)	N147S	unknown	Het
Rttn	C	T	18: 89,013,737 (GRCm39)	H469Y	probably benign	Het
Slc2a12	T	C	10: 22,540,583 (GRCm39)	V146A	probably damaging	Het
Sptlc3	A	G	2: 139,388,341 (GRCm39)	E111G	possibly damaging	Het
Zfp108	T	C	7: 23,957,872 (GRCm39)		probably benign	Het
Zfp719	T	A	7: 43,240,554 (GRCm39)	F714Y	probably damaging	Het

Other mutations in Gvin-ps3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00971:Gvin-ps3	APN	7	105,681,008 (GRCm39)	exon	noncoding transcript
IGL01125:Gvin-ps3	APN	7	105,682,021 (GRCm39)	missense	unknown	0.00
R1184:Gvin-ps3	UTSW	7	105,683,159 (GRCm39)	missense	probably benign	0.03
R1411:Gvin-ps3	UTSW	7	105,682,686 (GRCm39)	missense	probably benign	0.39
R2198:Gvin-ps3	UTSW	7	105,682,758 (GRCm39)	missense	probably benign	0.00
R2311:Gvin-ps3	UTSW	7	105,682,797 (GRCm39)	missense	probably damaging	0.99
R2380:Gvin-ps3	UTSW	7	105,681,374 (GRCm39)	missense	possibly damaging	0.86
R3825:Gvin-ps3	UTSW	7	105,682,780 (GRCm39)	missense	possibly damaging	0.92
R4397:Gvin-ps3	UTSW	7	105,682,130 (GRCm39)	exon	noncoding transcript
R4693:Gvin-ps3	UTSW	7	105,681,585 (GRCm39)	exon	noncoding transcript
R4787:Gvin-ps3	UTSW	7	105,681,041 (GRCm39)	exon	noncoding transcript
R4840:Gvin-ps3	UTSW	7	105,680,627 (GRCm39)	exon	noncoding transcript
R4972:Gvin-ps3	UTSW	7	105,682,521 (GRCm39)	exon	noncoding transcript
R5221:Gvin-ps3	UTSW	7	105,683,181 (GRCm39)	exon	noncoding transcript
R5296:Gvin-ps3	UTSW	7	105,681,055 (GRCm39)	exon	noncoding transcript

Posted On

2013-11-05