Mutagenetix > Incidental Mutation

Incidental Mutation 'R0960:Flnc'

81820

Institutional Source

Beutler Lab

Gene Symbol

Flnc

Ensembl Gene

ENSMUSG00000068699

Gene Name

filamin C, gamma

Synonyms

1110055E19Rik, Fln2, actin binding protein 280

MMRRC Submission

039089-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R0960 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

29433255-29461882 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 29441511 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 431 (D431G)

Ref Sequence

ENSEMBL: ENSMUSP00000099139 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000065090] [ENSMUST00000101617]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000065090
AA Change: D431G

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000064163
Gene: ENSMUSG00000068699
AA Change: D431G

Domain	Start	End	E-Value	Type
CH	39	141	1.17e-25	SMART
CH	162	258	2.09e-22	SMART
IG_FLMN	275	372	3.84e-38	SMART
IG_FLMN	375	472	3.73e-36	SMART
IG_FLMN	474	569	4.41e-38	SMART
IG_FLMN	571	662	3.61e-34	SMART
IG_FLMN	667	762	2.48e-41	SMART
IG_FLMN	764	865	6.7e-29	SMART
IG_FLMN	867	964	3.42e-35	SMART
IG_FLMN	966	1060	2.92e-29	SMART
IG_FLMN	1062	1153	3.69e-40	SMART
IG_FLMN	1155	1248	6.53e-41	SMART
IG_FLMN	1250	1348	7.23e-34	SMART
IG_FLMN	1350	1441	2.04e-42	SMART
IG_FLMN	1443	1537	1.75e-41	SMART
IG_FLMN	1539	1634	1.31e-40	SMART
IG_FLMN	1636	1738	1.05e-30	SMART
IG_FLMN	1777	1858	2.93e-11	SMART
IG_FLMN	1859	1950	2.55e-43	SMART
IG_FLMN	1951	2037	2.43e-17	SMART
IG_FLMN	2041	2132	1.52e-41	SMART
PDB:2E9I\|A	2133	2162	3e-7	PDB
IG_FLMN	2217	2310	2.93e-11	SMART
IG_FLMN	2314	2405	1.67e-38	SMART
IG_FLMN	2408	2500	2.56e-25	SMART
IG_FLMN	2505	2596	9.54e-34	SMART
low complexity region	2618	2628	N/A	INTRINSIC
IG_FLMN	2635	2737	2.11e-26	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000101617
AA Change: D431G

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000099139
Gene: ENSMUSG00000068699
AA Change: D431G

Domain	Start	End	E-Value	Type
CH	39	141	1.17e-25	SMART
CH	162	258	2.09e-22	SMART
IG_FLMN	275	372	3.84e-38	SMART
IG_FLMN	375	472	3.73e-36	SMART
IG_FLMN	474	569	4.41e-38	SMART
IG_FLMN	571	662	3.61e-34	SMART
IG_FLMN	667	762	2.48e-41	SMART
IG_FLMN	764	865	6.7e-29	SMART
IG_FLMN	867	964	3.42e-35	SMART
IG_FLMN	966	1060	2.92e-29	SMART
IG_FLMN	1062	1153	3.69e-40	SMART
IG_FLMN	1155	1248	6.53e-41	SMART
IG_FLMN	1250	1348	7.23e-34	SMART
IG_FLMN	1350	1441	2.04e-42	SMART
IG_FLMN	1443	1537	1.75e-41	SMART
IG_FLMN	1539	1634	1.31e-40	SMART
IG_FLMN	1636	1738	6.11e-32	SMART
IG_FLMN	1744	1825	2.93e-11	SMART
IG_FLMN	1826	1917	2.55e-43	SMART
IG_FLMN	1918	2004	2.43e-17	SMART
IG_FLMN	2008	2099	1.52e-41	SMART
PDB:2E9I\|A	2100	2129	3e-7	PDB
IG_FLMN	2184	2277	2.93e-11	SMART
IG_FLMN	2281	2372	1.67e-38	SMART
IG_FLMN	2375	2467	2.56e-25	SMART
IG_FLMN	2472	2563	9.54e-34	SMART
low complexity region	2585	2595	N/A	INTRINSIC
IG_FLMN	2602	2704	2.11e-26	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000148404

Meta Mutation Damage Score

0.2016

Coding Region Coverage

1x: 99.5%
3x: 99.0%
10x: 97.8%
20x: 96.0%

Validation Efficiency

98% (49/50)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a hypomorphic allele display neonatal lethality, respiratory failure, reduced skeletal muscle mass, and abnormal skeletal muscle fiber morphology. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 48 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1810009A15Rik	T	C	19: 8,867,792 (GRCm39)	V256A	probably benign	Het
4930433I11Rik	A	T	7: 40,642,480 (GRCm39)	T141S	probably benign	Het
4930474N05Rik	C	A	14: 35,818,367 (GRCm39)	H122N	probably benign	Het
Aamp	T	C	1: 74,320,304 (GRCm39)	T341A	possibly damaging	Het
Adam26a	A	T	8: 44,021,800 (GRCm39)	H563Q	probably damaging	Het
Ankrd13a	G	A	5: 114,924,868 (GRCm39)	E118K	probably benign	Het
Asic5	A	G	3: 81,913,847 (GRCm39)	I174V	probably benign	Het
Atad2b	G	A	12: 5,056,593 (GRCm39)		probably benign	Het
Bub1b	A	G	2: 118,437,161 (GRCm39)	I120V	probably benign	Het
Casp8	T	C	1: 58,868,172 (GRCm39)		probably null	Het
Cdk5rap2	A	G	4: 70,161,745 (GRCm39)	Y254H	probably benign	Het
Clasp1	T	C	1: 118,479,756 (GRCm39)	I996T	probably benign	Het
Cntn6	A	G	6: 104,751,441 (GRCm39)	I294V	probably benign	Het
Gm4884	T	A	7: 40,692,232 (GRCm39)	M67K	possibly damaging	Het
Hmx3	T	C	7: 131,145,043 (GRCm39)	Y118H	probably benign	Het
Hsf2bp	C	T	17: 32,226,743 (GRCm39)	R204H	probably damaging	Het
Il12b	G	T	11: 44,299,315 (GRCm39)	C128F	probably damaging	Het
Ints6	T	C	14: 62,947,015 (GRCm39)	M317V	probably benign	Het
Iqca1	C	A	1: 90,070,453 (GRCm39)	G133V	probably null	Het
Kcnh2	C	T	5: 24,527,670 (GRCm39)	R894H	probably damaging	Het
Kif27	T	C	13: 58,471,781 (GRCm39)	E769G	probably damaging	Het
Kif28	G	A	1: 179,523,370 (GRCm39)	Q987*	probably null	Het
Klhdc3	T	C	17: 46,987,444 (GRCm39)	H330R	possibly damaging	Het
Leo1	G	A	9: 75,352,522 (GRCm39)	E22K	probably benign	Het
Lpcat2	C	T	8: 93,596,338 (GRCm39)	T125M	probably benign	Het
Map1a	A	G	2: 121,132,124 (GRCm39)	Y742C	probably benign	Het
Mllt6	C	T	11: 97,555,772 (GRCm39)		probably benign	Het
Mpp2	A	G	11: 101,952,411 (GRCm39)	V354A	possibly damaging	Het
Mroh2a	C	A	1: 88,170,142 (GRCm39)	A685D	possibly damaging	Het
Myo10	A	G	15: 25,801,275 (GRCm39)	E1488G	probably damaging	Het
Neb	A	G	2: 52,102,995 (GRCm39)	V4461A	probably benign	Het
Nudcd1	G	T	15: 44,291,047 (GRCm39)		probably benign	Het
Or10ag59	T	C	2: 87,406,279 (GRCm39)	Y284H	probably benign	Het
Or2w1b	A	C	13: 21,300,435 (GRCm39)	D191A	possibly damaging	Het
Pde1a	G	A	2: 79,695,378 (GRCm39)		probably benign	Het
Sdha	A	T	13: 74,471,303 (GRCm39)		probably benign	Het
Selenoo	T	G	15: 88,980,957 (GRCm39)	I432S	probably benign	Het
Sh3gl2	A	T	4: 85,295,717 (GRCm39)	I140F	probably damaging	Het
Svopl	G	T	6: 37,993,992 (GRCm39)	Y346*	probably null	Het
Tbc1d17	C	T	7: 44,497,852 (GRCm39)		probably benign	Het
Tlr3	A	C	8: 45,850,452 (GRCm39)	I815S	probably damaging	Het
Tmem25	T	A	9: 44,706,809 (GRCm39)		probably null	Het
Tpd52	A	T	3: 9,008,650 (GRCm39)		probably null	Het
Tspoap1	A	T	11: 87,661,421 (GRCm39)		probably benign	Het
Txndc11	A	T	16: 10,909,453 (GRCm39)	D364E	probably benign	Het
Unc5cl	G	T	17: 48,766,624 (GRCm39)		probably benign	Het
Vmn1r13	A	G	6: 57,186,996 (GRCm39)	M52V	probably benign	Het
Zap70	T	C	1: 36,818,254 (GRCm39)	Y314H	probably damaging	Het

Other mutations in Flnc

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00952:Flnc	APN	6	29,459,546 (GRCm39)	nonsense	probably null
IGL01099:Flnc	APN	6	29,433,617 (GRCm39)	missense	probably damaging	0.99
IGL01656:Flnc	APN	6	29,443,507 (GRCm39)	splice site	probably benign
IGL01659:Flnc	APN	6	29,448,670 (GRCm39)	missense	probably damaging	0.98
IGL01780:Flnc	APN	6	29,438,492 (GRCm39)	nonsense	probably null
IGL01935:Flnc	APN	6	29,454,279 (GRCm39)	missense	probably damaging	1.00
IGL02039:Flnc	APN	6	29,450,718 (GRCm39)	missense	probably benign	0.05
IGL02119:Flnc	APN	6	29,447,511 (GRCm39)	missense	probably damaging	0.98
IGL02122:Flnc	APN	6	29,444,335 (GRCm39)	missense	possibly damaging	0.70
IGL02236:Flnc	APN	6	29,454,375 (GRCm39)	missense	probably damaging	1.00
IGL02350:Flnc	APN	6	29,438,492 (GRCm39)	nonsense	probably null
IGL02357:Flnc	APN	6	29,438,492 (GRCm39)	nonsense	probably null
IGL02428:Flnc	APN	6	29,451,484 (GRCm39)	missense	probably damaging	1.00
IGL02496:Flnc	APN	6	29,440,684 (GRCm39)	missense	probably damaging	0.98
IGL02516:Flnc	APN	6	29,450,840 (GRCm39)	missense	probably damaging	0.99
IGL02696:Flnc	APN	6	29,446,697 (GRCm39)	missense	probably damaging	0.98
IGL03165:Flnc	APN	6	29,449,377 (GRCm39)	missense	probably damaging	1.00
IGL03190:Flnc	APN	6	29,445,636 (GRCm39)	splice site	probably benign
I1329:Flnc	UTSW	6	29,451,414 (GRCm39)	missense	probably damaging	1.00
R0111:Flnc	UTSW	6	29,454,339 (GRCm39)	missense	probably damaging	0.99
R0665:Flnc	UTSW	6	29,455,530 (GRCm39)	missense	probably damaging	1.00
R0748:Flnc	UTSW	6	29,446,343 (GRCm39)	missense	probably damaging	0.99
R1328:Flnc	UTSW	6	29,438,612 (GRCm39)	missense	probably damaging	1.00
R1502:Flnc	UTSW	6	29,438,693 (GRCm39)	missense	probably benign	0.45
R1544:Flnc	UTSW	6	29,444,079 (GRCm39)	missense	probably benign	0.00
R1565:Flnc	UTSW	6	29,455,170 (GRCm39)	missense	probably damaging	1.00
R1640:Flnc	UTSW	6	29,433,806 (GRCm39)	missense	possibly damaging	0.78
R1691:Flnc	UTSW	6	29,441,213 (GRCm39)	missense	probably benign	0.09
R1818:Flnc	UTSW	6	29,457,447 (GRCm39)	missense	probably damaging	1.00
R1826:Flnc	UTSW	6	29,455,184 (GRCm39)	missense	probably damaging	0.99
R1851:Flnc	UTSW	6	29,443,478 (GRCm39)	missense	probably damaging	1.00
R1898:Flnc	UTSW	6	29,438,665 (GRCm39)	nonsense	probably null
R1905:Flnc	UTSW	6	29,459,459 (GRCm39)	missense	probably damaging	1.00
R1985:Flnc	UTSW	6	29,444,415 (GRCm39)	splice site	probably benign
R2016:Flnc	UTSW	6	29,443,796 (GRCm39)	critical splice donor site	probably null
R2017:Flnc	UTSW	6	29,443,796 (GRCm39)	critical splice donor site	probably null
R2020:Flnc	UTSW	6	29,444,362 (GRCm39)	missense	probably damaging	0.97
R2104:Flnc	UTSW	6	29,450,734 (GRCm39)	critical splice donor site	probably null
R2132:Flnc	UTSW	6	29,443,675 (GRCm39)	missense	probably damaging	1.00
R2141:Flnc	UTSW	6	29,448,674 (GRCm39)	missense	probably damaging	1.00
R2197:Flnc	UTSW	6	29,459,134 (GRCm39)	missense	probably damaging	1.00
R2202:Flnc	UTSW	6	29,459,507 (GRCm39)	missense	probably damaging	1.00
R2203:Flnc	UTSW	6	29,459,507 (GRCm39)	missense	probably damaging	1.00
R2204:Flnc	UTSW	6	29,459,507 (GRCm39)	missense	probably damaging	1.00
R2205:Flnc	UTSW	6	29,459,507 (GRCm39)	missense	probably damaging	1.00
R2209:Flnc	UTSW	6	29,455,844 (GRCm39)	missense	possibly damaging	0.91
R2248:Flnc	UTSW	6	29,451,400 (GRCm39)	missense	probably damaging	0.99
R2258:Flnc	UTSW	6	29,438,665 (GRCm39)	nonsense	probably null
R2259:Flnc	UTSW	6	29,438,665 (GRCm39)	nonsense	probably null
R2280:Flnc	UTSW	6	29,438,665 (GRCm39)	nonsense	probably null
R2281:Flnc	UTSW	6	29,438,665 (GRCm39)	nonsense	probably null
R2873:Flnc	UTSW	6	29,447,542 (GRCm39)	missense	probably damaging	0.96
R2900:Flnc	UTSW	6	29,448,584 (GRCm39)	missense	probably damaging	0.98
R3788:Flnc	UTSW	6	29,454,056 (GRCm39)	missense	probably damaging	0.99
R3799:Flnc	UTSW	6	29,443,738 (GRCm39)	missense	probably damaging	1.00
R3801:Flnc	UTSW	6	29,447,403 (GRCm39)	missense	probably damaging	0.98
R3851:Flnc	UTSW	6	29,453,718 (GRCm39)	missense	probably damaging	1.00
R3910:Flnc	UTSW	6	29,459,426 (GRCm39)	missense	probably damaging	1.00
R3982:Flnc	UTSW	6	29,442,940 (GRCm39)	missense	probably damaging	1.00
R3983:Flnc	UTSW	6	29,442,940 (GRCm39)	missense	probably damaging	1.00
R4023:Flnc	UTSW	6	29,451,634 (GRCm39)	missense	possibly damaging	0.95
R4676:Flnc	UTSW	6	29,445,153 (GRCm39)	splice site	probably null
R4694:Flnc	UTSW	6	29,443,447 (GRCm39)	missense	probably damaging	1.00
R4695:Flnc	UTSW	6	29,440,428 (GRCm39)	missense	probably damaging	0.99
R4735:Flnc	UTSW	6	29,455,812 (GRCm39)	missense	probably damaging	1.00
R4773:Flnc	UTSW	6	29,445,038 (GRCm39)	missense	possibly damaging	0.96
R4828:Flnc	UTSW	6	29,455,166 (GRCm39)	missense	probably damaging	1.00
R4856:Flnc	UTSW	6	29,447,889 (GRCm39)	missense	probably damaging	1.00
R4879:Flnc	UTSW	6	29,460,805 (GRCm39)	missense	probably damaging	0.99
R4899:Flnc	UTSW	6	29,446,842 (GRCm39)	missense	probably benign	0.17
R4906:Flnc	UTSW	6	29,447,524 (GRCm39)	missense	probably damaging	0.99
R5089:Flnc	UTSW	6	29,447,812 (GRCm39)	missense	probably damaging	0.96
R5173:Flnc	UTSW	6	29,455,537 (GRCm39)	missense	probably damaging	1.00
R5174:Flnc	UTSW	6	29,448,893 (GRCm39)	missense	possibly damaging	0.91
R5290:Flnc	UTSW	6	29,457,553 (GRCm39)	missense	probably damaging	1.00
R5338:Flnc	UTSW	6	29,444,063 (GRCm39)	missense	possibly damaging	0.47
R5352:Flnc	UTSW	6	29,449,317 (GRCm39)	missense	possibly damaging	0.85
R5397:Flnc	UTSW	6	29,441,160 (GRCm39)	missense	possibly damaging	0.87
R5431:Flnc	UTSW	6	29,456,383 (GRCm39)	missense	possibly damaging	0.74
R5481:Flnc	UTSW	6	29,441,216 (GRCm39)	missense	probably damaging	1.00
R5511:Flnc	UTSW	6	29,458,897 (GRCm39)	missense	probably damaging	1.00
R5539:Flnc	UTSW	6	29,446,229 (GRCm39)	missense	probably damaging	1.00
R5549:Flnc	UTSW	6	29,453,690 (GRCm39)	missense	probably damaging	1.00
R5567:Flnc	UTSW	6	29,444,044 (GRCm39)	nonsense	probably null
R5584:Flnc	UTSW	6	29,446,627 (GRCm39)	missense	probably damaging	0.98
R5689:Flnc	UTSW	6	29,441,591 (GRCm39)	missense	probably benign	0.03
R5753:Flnc	UTSW	6	29,433,488 (GRCm39)	missense	probably benign
R5786:Flnc	UTSW	6	29,459,536 (GRCm39)	nonsense	probably null
R5822:Flnc	UTSW	6	29,459,429 (GRCm39)	missense	probably damaging	0.98
R5823:Flnc	UTSW	6	29,461,201 (GRCm39)	missense	probably damaging	0.99
R5933:Flnc	UTSW	6	29,441,105 (GRCm39)	missense	probably damaging	0.99
R6043:Flnc	UTSW	6	29,446,607 (GRCm39)	missense	probably damaging	1.00
R6320:Flnc	UTSW	6	29,459,062 (GRCm39)	missense	probably damaging	1.00
R6337:Flnc	UTSW	6	29,454,318 (GRCm39)	missense	probably damaging	0.99
R6399:Flnc	UTSW	6	29,458,882 (GRCm39)	missense	probably damaging	1.00
R6423:Flnc	UTSW	6	29,445,155 (GRCm39)	splice site	probably null
R6540:Flnc	UTSW	6	29,446,376 (GRCm39)	missense	possibly damaging	0.96
R6547:Flnc	UTSW	6	29,448,607 (GRCm39)	missense	probably damaging	0.98
R6717:Flnc	UTSW	6	29,450,901 (GRCm39)	small deletion	probably benign
R6875:Flnc	UTSW	6	29,445,748 (GRCm39)	missense	probably damaging	1.00
R7193:Flnc	UTSW	6	29,450,870 (GRCm39)	missense	probably damaging	1.00
R7255:Flnc	UTSW	6	29,445,765 (GRCm39)	missense	probably damaging	1.00
R7303:Flnc	UTSW	6	29,460,849 (GRCm39)	missense	probably benign	0.31
R7413:Flnc	UTSW	6	29,452,258 (GRCm39)	missense	probably damaging	1.00
R7422:Flnc	UTSW	6	29,455,470 (GRCm39)	missense	probably damaging	1.00
R7559:Flnc	UTSW	6	29,459,009 (GRCm39)	missense	probably damaging	1.00
R7632:Flnc	UTSW	6	29,446,984 (GRCm39)	missense	probably damaging	0.98
R7651:Flnc	UTSW	6	29,444,049 (GRCm39)	missense	probably benign	0.08
R7679:Flnc	UTSW	6	29,456,789 (GRCm39)	missense	probably benign	0.00
R7697:Flnc	UTSW	6	29,456,516 (GRCm39)	missense	probably damaging	0.98
R7788:Flnc	UTSW	6	29,456,443 (GRCm39)	missense	possibly damaging	0.67
R7852:Flnc	UTSW	6	29,440,897 (GRCm39)	missense	probably damaging	1.00
R7870:Flnc	UTSW	6	29,454,306 (GRCm39)	missense	probably damaging	1.00
R7873:Flnc	UTSW	6	29,456,990 (GRCm39)	missense	possibly damaging	0.88
R7921:Flnc	UTSW	6	29,447,769 (GRCm39)	missense	possibly damaging	0.58
R7950:Flnc	UTSW	6	29,456,381 (GRCm39)	missense	possibly damaging	0.61
R7953:Flnc	UTSW	6	29,447,828 (GRCm39)	missense	probably damaging	0.99
R7970:Flnc	UTSW	6	29,447,525 (GRCm39)	missense	possibly damaging	0.96
R8071:Flnc	UTSW	6	29,457,445 (GRCm39)	missense	probably damaging	1.00
R8143:Flnc	UTSW	6	29,441,484 (GRCm39)	missense	probably benign	0.20
R8166:Flnc	UTSW	6	29,433,731 (GRCm39)	missense	probably damaging	0.99
R8167:Flnc	UTSW	6	29,455,921 (GRCm39)	missense	probably damaging	0.98
R8306:Flnc	UTSW	6	29,449,369 (GRCm39)	missense	probably benign	0.05
R8428:Flnc	UTSW	6	29,450,849 (GRCm39)	missense	probably benign	0.36
R8466:Flnc	UTSW	6	29,438,621 (GRCm39)	missense	probably damaging	0.98
R8671:Flnc	UTSW	6	29,443,501 (GRCm39)	critical splice donor site	probably null
R8885:Flnc	UTSW	6	29,455,410 (GRCm39)	missense	probably damaging	0.96
R8922:Flnc	UTSW	6	29,456,835 (GRCm39)	missense	probably damaging	0.99
R8923:Flnc	UTSW	6	29,452,236 (GRCm39)	missense	probably damaging	1.00
R8985:Flnc	UTSW	6	29,440,499 (GRCm39)	missense	probably benign	0.37
R9075:Flnc	UTSW	6	29,447,646 (GRCm39)	missense	probably damaging	0.96
R9098:Flnc	UTSW	6	29,455,518 (GRCm39)	nonsense	probably null
R9162:Flnc	UTSW	6	29,455,860 (GRCm39)	missense	probably damaging	1.00
R9199:Flnc	UTSW	6	29,441,490 (GRCm39)	missense	probably benign	0.31
R9204:Flnc	UTSW	6	29,452,353 (GRCm39)	missense	possibly damaging	0.93
R9273:Flnc	UTSW	6	29,447,815 (GRCm39)	missense	probably benign	0.08
R9411:Flnc	UTSW	6	29,441,484 (GRCm39)	missense	probably benign
R9412:Flnc	UTSW	6	29,441,484 (GRCm39)	missense	probably benign
R9413:Flnc	UTSW	6	29,441,484 (GRCm39)	missense	probably benign
R9451:Flnc	UTSW	6	29,445,462 (GRCm39)	missense	probably damaging	0.98
R9524:Flnc	UTSW	6	29,461,109 (GRCm39)	missense	probably damaging	1.00
R9575:Flnc	UTSW	6	29,454,399 (GRCm39)	missense	probably damaging	0.98
R9582:Flnc	UTSW	6	29,460,736 (GRCm39)	missense	probably damaging	0.99
R9595:Flnc	UTSW	6	29,433,720 (GRCm39)	missense	probably benign	0.05
R9664:Flnc	UTSW	6	29,457,214 (GRCm39)	missense	probably damaging	1.00
R9665:Flnc	UTSW	6	29,455,447 (GRCm39)	missense	probably damaging	1.00
R9686:Flnc	UTSW	6	29,456,434 (GRCm39)	missense	possibly damaging	0.84
Z1088:Flnc	UTSW	6	29,457,150 (GRCm39)	missense	probably damaging	1.00
Z1177:Flnc	UTSW	6	29,457,129 (GRCm39)	missense	probably damaging	1.00
Z1177:Flnc	UTSW	6	29,447,544 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GAGCGTAGTCCCTTTGAGGTGAATG -3'
(R):5'- TCTGGCTCTGGTGAGGTAAAGCAG -3'

Sequencing Primer
(F):5'- GTAGCCTCTGACAGTGTACAG -3'
(R):5'- AGGTAAAGCAGCCTTACCTTCTG -3'

Posted On

2013-11-08