Mutagenetix > Incidental Mutation

Incidental Mutation 'R0879:Gm4775'

81942

Institutional Source

Beutler Lab

Gene Symbol

Gm4775

Ensembl Gene

ENSMUSG00000090538

Gene Name

predicted gene 4775

Synonyms

MMRRC Submission

039046-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.219) question?

Stock #

R0879 (G1)

Quality Score

165

Status

Validated

Chromosome

Chromosomal Location

106338199-106338600 bp(-) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

T to C at 106338227 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000131676 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000169588]

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000169588

SMART Domains

Protein: ENSMUSP00000131676
Gene: ENSMUSG00000090538

Domain	Start	End	E-Value	Type
Pfam:Ribosomal_S19	40	118	6.7e-37	PFAM

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.5%
3x: 99.0%
10x: 97.9%
20x: 96.3%

Validation Efficiency

100% (41/41)

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aagab	T	A	9: 63,524,892 (GRCm39)		probably benign	Het
Adm	A	G	7: 110,227,559 (GRCm39)	D25G	possibly damaging	Het
Adprs	C	T	4: 126,210,410 (GRCm39)	V357I	probably benign	Het
Akap6	G	T	12: 52,927,582 (GRCm39)	R164L	probably damaging	Het
Baz2a	A	G	10: 127,957,173 (GRCm39)	N972S	probably damaging	Het
Brd2	A	T	17: 34,332,420 (GRCm39)	V232D	probably benign	Het
C6	A	G	15: 4,792,818 (GRCm39)		probably benign	Het
Ceacam5	A	C	7: 17,491,627 (GRCm39)	I666L	probably benign	Het
Col7a1	T	C	9: 108,805,159 (GRCm39)		probably benign	Het
Dnah17	C	T	11: 117,947,661 (GRCm39)		probably benign	Het
Dnah7a	A	T	1: 53,467,019 (GRCm39)	V3615E	possibly damaging	Het
Eml6	A	G	11: 29,800,816 (GRCm39)		probably null	Het
Enpp2	T	C	15: 54,741,326 (GRCm39)	E324G	probably damaging	Het
Fgd4	A	G	16: 16,295,313 (GRCm39)	V222A	probably damaging	Het
Gm4076	A	G	13: 85,275,326 (GRCm39)		noncoding transcript	Het
Igsf9b	T	C	9: 27,245,038 (GRCm39)	S1002P	probably damaging	Het
Jag1	A	G	2: 136,942,001 (GRCm39)	S244P	possibly damaging	Het
Klhl41	A	T	2: 69,513,827 (GRCm39)		probably benign	Het
Ltbr	A	G	6: 125,290,338 (GRCm39)		probably benign	Het
Megf8	A	G	7: 25,037,896 (GRCm39)	E804G	possibly damaging	Het
Mybpc1	G	A	10: 88,407,378 (GRCm39)		probably benign	Het
Npas4	T	C	19: 5,036,944 (GRCm39)	R407G	probably benign	Het
Oxnad1	T	A	14: 31,821,553 (GRCm39)	Y213N	probably damaging	Het
Pde6d	A	G	1: 86,473,523 (GRCm39)	F91S	probably benign	Het
Pelp1	A	G	11: 70,286,123 (GRCm39)		probably benign	Het
Plscr2	T	C	9: 92,169,846 (GRCm39)	Y99H	probably damaging	Het
Rft1	T	C	14: 30,404,705 (GRCm39)		probably benign	Het
Ryr3	T	C	2: 112,860,588 (GRCm39)	Y30C	probably benign	Het
Selenbp2	A	G	3: 94,606,863 (GRCm39)	T108A	possibly damaging	Het
Stk32b	A	G	5: 37,616,940 (GRCm39)		probably benign	Het
Stra6	T	C	9: 58,042,487 (GRCm39)		probably null	Het
Usp17le	A	T	7: 104,418,854 (GRCm39)	L96Q	probably damaging	Het
Usp17le	G	T	7: 104,418,855 (GRCm39)	L96M	possibly damaging	Het
Vmn1r76	A	T	7: 11,664,662 (GRCm39)	I184N	probably benign	Het
Vmn2r102	T	C	17: 19,914,454 (GRCm39)	V673A	probably damaging	Het
Wdr17	T	G	8: 55,114,516 (GRCm39)	I667L	probably benign	Het
Zfp292	T	C	4: 34,811,218 (GRCm39)	T609A	probably benign	Het
Zfp821	T	C	8: 110,448,474 (GRCm39)	I135T	possibly damaging	Het
Zfp865	A	G	7: 5,034,342 (GRCm39)	T776A	probably benign	Het
Zp2	G	T	7: 119,734,757 (GRCm39)	P477Q	probably damaging	Het

Other mutations in Gm4775

Allele	Source	Chr	Coord	Type	Predicted Effect
R5409:Gm4775	UTSW	14	106,338,386 (GRCm39)	exon	noncoding transcript
R5504:Gm4775	UTSW	14	106,338,389 (GRCm39)	exon	noncoding transcript
Z1088:Gm4775	UTSW	14	106,338,399 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- TGTCTACACCCATGCAGACATGC -3'
(R):5'- ACTGCCAAGATGGCCTAAGTGGAG -3'

Sequencing Primer
(F):5'- TGCAGACATGCATACCATGAAAATG -3'
(R):5'- CACCTATGGTGGTGTAGACCTC -3'

Posted On

2013-11-08