Mutagenetix > Incidental Mutation

Incidental Mutation 'R0906:Gm6729'

83329

Institutional Source

Beutler Lab

Gene Symbol

Gm6729

Ensembl Gene

ENSMUSG00000090816

Gene Name

predicted gene 6729

Synonyms

MMRRC Submission

039064-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.076) question?

Stock #

R0906 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

86362161-86377447 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to C at 86376456 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000165173

SMART Domains

Protein: ENSMUSP00000133178
Gene: ENSMUSG00000090816

Domain	Start	End	E-Value	Type
S_TKc	14	262	4.3e-87	SMART
UBA	276	313	2.99e-4	SMART
low complexity region	327	341	N/A	INTRINSIC
low complexity region	450	465	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000219485

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.5%
3x: 99.0%
10x: 97.8%
20x: 96.3%

Validation Efficiency

100% (33/33)

Allele List at MGI

Other mutations in this stock

Total: 33 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
AA986860	T	A	1: 130,665,430 (GRCm39)		probably benign	Het
Atp7b	T	C	8: 22,517,842 (GRCm39)	H332R	probably benign	Het
Bace2	C	T	16: 97,158,141 (GRCm39)	P47L	possibly damaging	Het
Cyp2c39	A	G	19: 39,499,315 (GRCm39)	M1V	probably null	Het
Dcbld2	A	G	16: 58,275,610 (GRCm39)	E442G	probably damaging	Het
Gm14496	A	G	2: 181,642,308 (GRCm39)	T660A	probably damaging	Het
Gm4945	A	C	17: 47,353,796 (GRCm39)		noncoding transcript	Het
Golga1	G	A	2: 38,937,655 (GRCm39)	R204W	probably damaging	Het
Guf1	T	C	5: 69,723,729 (GRCm39)	I348T	probably damaging	Het
Htra4	T	A	8: 25,527,160 (GRCm39)	I212L	probably benign	Het
Itih5	G	A	2: 10,253,999 (GRCm39)	R750Q	probably benign	Het
Lgalsl2	T	C	7: 5,362,828 (GRCm39)	I153T	probably damaging	Het
Lgr6	C	T	1: 134,921,748 (GRCm39)	A199T	probably damaging	Het
Naip2	C	T	13: 100,298,368 (GRCm39)	G556D	probably benign	Het
Naip2	T	C	13: 100,298,362 (GRCm39)	E558G	probably benign	Het
Nsd1	T	C	13: 55,425,403 (GRCm39)	V1520A	probably benign	Het
Nuak1	C	T	10: 84,211,144 (GRCm39)	V315I	probably damaging	Het
Nup205	G	T	6: 35,213,827 (GRCm39)	G1740C	probably damaging	Het
Or1r1	G	C	11: 73,874,685 (GRCm39)	L250V	probably damaging	Het
Pclo	T	C	5: 14,726,700 (GRCm39)		probably benign	Het
Pik3r6	T	C	11: 68,426,927 (GRCm39)		probably benign	Het
Pikfyve	T	A	1: 65,292,556 (GRCm39)	F1336I	probably damaging	Het
Pla2r1	A	G	2: 60,345,291 (GRCm39)	I355T	possibly damaging	Het
Rgs22	A	T	15: 36,104,048 (GRCm39)		probably benign	Het
Sec63	T	A	10: 42,677,924 (GRCm39)	M312K	probably damaging	Het
Slc2a5	T	C	4: 150,227,287 (GRCm39)	I401T	probably benign	Het
Slc9a8	G	T	2: 167,276,787 (GRCm39)		probably benign	Het
Stab1	T	C	14: 30,867,206 (GRCm39)	E1718G	probably benign	Het
Terb1	A	T	8: 105,179,268 (GRCm39)	I640N	probably damaging	Het
Tmem217	A	G	17: 29,745,490 (GRCm39)	L80P	probably damaging	Het
Topbp1	C	T	9: 103,205,792 (GRCm39)	P810L	probably benign	Het
Ttbk2	G	A	2: 120,614,262 (GRCm39)	R151C	probably damaging	Het
Vmn2r88	T	G	14: 51,655,666 (GRCm39)	L626R	probably damaging	Het

Other mutations in Gm6729

Allele	Source	Chr	Coord	Type	Predicted Effect
R1034:Gm6729	UTSW	10	86,375,890 (GRCm39)	unclassified	noncoding transcript
R1052:Gm6729	UTSW	10	86,376,799 (GRCm39)	unclassified	noncoding transcript
R1523:Gm6729	UTSW	10	86,376,039 (GRCm39)	unclassified	noncoding transcript
R1922:Gm6729	UTSW	10	86,376,782 (GRCm39)	unclassified	noncoding transcript
R3498:Gm6729	UTSW	10	86,376,582 (GRCm39)	unclassified	noncoding transcript
R4133:Gm6729	UTSW	10	86,377,030 (GRCm39)	unclassified	noncoding transcript
R4193:Gm6729	UTSW	10	86,376,483 (GRCm39)	unclassified	noncoding transcript
R4940:Gm6729	UTSW	10	86,376,252 (GRCm39)	unclassified	noncoding transcript
X0028:Gm6729	UTSW	10	86,376,648 (GRCm39)	unclassified	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- CCAACTTGTGTCCTGATAGTGGCAG -3'
(R):5'- TCAAGCTCAGCCCTGGCAGATTAC -3'

Sequencing Primer
(F):5'- CCAAAGTTGGGTTCACTGC -3'
(R):5'- TCATGCTAGGGGAGCCATAC -3'

Posted On

2013-11-08