Incidental Mutation 'R0894:Abca8a'
| ID |
83689 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abca8a
|
| Ensembl Gene |
ENSMUSG00000041828 |
| Gene Name |
ATP-binding cassette, sub-family A member 8a |
| Synonyms |
|
| MMRRC Submission |
039057-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.056)
|
| Stock # |
R0894 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
109916460-109986804 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 109941792 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 1159
(I1159T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102275
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046223]
[ENSMUST00000100287]
[ENSMUST00000106664]
|
| AlphaFold |
Q8K442 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000046223
AA Change: I1158T
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000045808
Gene: ENSMUSG00000041828
AA Change: I1158T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
27 |
416 |
8e-26 |
PFAM |
|
AAA
|
505 |
689 |
6.27e-9 |
SMART |
|
Pfam:ABC2_membrane_3
|
860 |
1174 |
6.8e-15 |
PFAM |
|
transmembrane domain
|
1196 |
1218 |
N/A |
INTRINSIC |
|
low complexity region
|
1246 |
1255 |
N/A |
INTRINSIC |
|
low complexity region
|
1288 |
1301 |
N/A |
INTRINSIC |
|
AAA
|
1313 |
1493 |
4.3e-7 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100287
AA Change: I1159T
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000097860
Gene: ENSMUSG00000041828
AA Change: I1159T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
27 |
416 |
3.9e-26 |
PFAM |
|
AAA
|
506 |
690 |
6.27e-9 |
SMART |
|
Pfam:ABC2_membrane_3
|
861 |
1175 |
3.3e-15 |
PFAM |
|
transmembrane domain
|
1197 |
1219 |
N/A |
INTRINSIC |
|
low complexity region
|
1247 |
1256 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1302 |
N/A |
INTRINSIC |
|
AAA
|
1314 |
1494 |
4.3e-7 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106664
AA Change: I1159T
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000102275
Gene: ENSMUSG00000041828
AA Change: I1159T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
28 |
416 |
1.7e-23 |
PFAM |
|
AAA
|
506 |
690 |
6.27e-9 |
SMART |
|
Pfam:ABC2_membrane_3
|
861 |
1214 |
1.3e-12 |
PFAM |
|
low complexity region
|
1247 |
1256 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1302 |
N/A |
INTRINSIC |
|
AAA
|
1314 |
1494 |
4.3e-7 |
SMART |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.5%
- 3x: 99.0%
- 10x: 97.7%
- 20x: 95.8%
|
| Validation Efficiency |
97% (102/105) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 104 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2210408I21Rik |
A |
G |
13: 77,471,726 (GRCm39) |
S1044G |
probably benign |
Het |
| Aanat |
A |
G |
11: 116,487,730 (GRCm39) |
H143R |
probably benign |
Het |
| Abcb1a |
G |
T |
5: 8,724,856 (GRCm39) |
|
probably benign |
Het |
| Abcc1 |
T |
C |
16: 14,283,001 (GRCm39) |
V1159A |
possibly damaging |
Het |
| Akr1e1 |
T |
A |
13: 4,645,071 (GRCm39) |
Q204L |
probably damaging |
Het |
| Alk |
T |
C |
17: 72,202,930 (GRCm39) |
Y1135C |
probably damaging |
Het |
| Atad2b |
C |
T |
12: 5,015,915 (GRCm39) |
T547I |
probably damaging |
Het |
| Brd10 |
T |
C |
19: 29,697,974 (GRCm39) |
|
probably benign |
Het |
| C030005K15Rik |
A |
T |
10: 97,561,648 (GRCm39) |
S28T |
unknown |
Het |
| Cdk5rap3 |
A |
G |
11: 96,799,654 (GRCm39) |
L387P |
probably damaging |
Het |
| Cfap95 |
T |
C |
19: 23,630,062 (GRCm39) |
E10G |
unknown |
Het |
| Cfap96 |
A |
G |
8: 46,409,497 (GRCm39) |
F274S |
probably damaging |
Het |
| Clec4f |
T |
A |
6: 83,629,979 (GRCm39) |
N193I |
probably damaging |
Het |
| Col4a4 |
A |
T |
1: 82,507,377 (GRCm39) |
|
probably null |
Het |
| Cplx4 |
T |
G |
18: 66,090,116 (GRCm39) |
D101A |
possibly damaging |
Het |
| Cpne8 |
A |
T |
15: 90,533,474 (GRCm39) |
D50E |
probably damaging |
Het |
| Csmd3 |
G |
T |
15: 47,721,316 (GRCm39) |
D1542E |
possibly damaging |
Het |
| Ctdp1 |
A |
G |
18: 80,512,736 (GRCm39) |
V9A |
probably benign |
Het |
| Ctnnd2 |
A |
T |
15: 30,332,301 (GRCm39) |
|
probably benign |
Het |
| Cyp7b1 |
C |
T |
3: 18,151,674 (GRCm39) |
A180T |
probably benign |
Het |
| Dcun1d5 |
C |
T |
9: 7,203,379 (GRCm39) |
|
probably benign |
Het |
| Dgat1 |
G |
T |
15: 76,387,199 (GRCm39) |
L363I |
possibly damaging |
Het |
| Dipk2b |
T |
A |
X: 18,289,791 (GRCm39) |
I224F |
possibly damaging |
Het |
| Dlg1 |
T |
A |
16: 31,561,965 (GRCm39) |
H120Q |
probably benign |
Het |
| Dnah6 |
T |
C |
6: 73,101,740 (GRCm39) |
N1928S |
probably benign |
Het |
| Dnai4 |
T |
C |
4: 102,906,583 (GRCm39) |
|
probably benign |
Het |
| Dync2h1 |
A |
T |
9: 7,041,734 (GRCm39) |
|
probably benign |
Het |
| Ednra |
T |
G |
8: 78,446,649 (GRCm39) |
|
probably benign |
Het |
| Efcab6 |
A |
T |
15: 83,802,493 (GRCm39) |
C845S |
probably benign |
Het |
| Egln1 |
A |
T |
8: 125,642,435 (GRCm39) |
C303S |
probably damaging |
Het |
| Eomes |
T |
C |
9: 118,311,368 (GRCm39) |
|
probably null |
Het |
| Epha1 |
A |
G |
6: 42,340,756 (GRCm39) |
V568A |
probably benign |
Het |
| Ercc6 |
T |
A |
14: 32,238,985 (GRCm39) |
N24K |
probably benign |
Het |
| Esco2 |
T |
C |
14: 66,064,726 (GRCm39) |
Q338R |
probably benign |
Het |
| Fbxo46 |
T |
C |
7: 18,869,654 (GRCm39) |
V91A |
probably damaging |
Het |
| Fryl |
A |
T |
5: 73,198,675 (GRCm39) |
|
probably benign |
Het |
| Gab3 |
A |
C |
X: 74,077,024 (GRCm39) |
D43E |
probably damaging |
Het |
| Gltpd2 |
T |
A |
11: 70,410,535 (GRCm39) |
|
probably benign |
Het |
| Gm17333 |
G |
T |
16: 77,649,711 (GRCm39) |
|
noncoding transcript |
Het |
| Gm7353 |
T |
C |
7: 3,160,570 (GRCm39) |
|
noncoding transcript |
Het |
| Grik4 |
T |
C |
9: 42,599,405 (GRCm39) |
|
probably benign |
Het |
| Gtpbp2 |
G |
T |
17: 46,476,895 (GRCm39) |
A358S |
possibly damaging |
Het |
| Hyls1 |
C |
T |
9: 35,472,528 (GRCm39) |
C296Y |
probably damaging |
Het |
| Igf2r |
C |
T |
17: 12,910,988 (GRCm39) |
M1943I |
probably benign |
Het |
| Iqca1l |
T |
C |
5: 24,755,731 (GRCm39) |
|
probably null |
Het |
| Ireb2 |
T |
A |
9: 54,803,861 (GRCm39) |
N517K |
probably damaging |
Het |
| Itga10 |
A |
G |
3: 96,560,976 (GRCm39) |
S614G |
possibly damaging |
Het |
| Kdm2b |
A |
G |
5: 123,122,523 (GRCm39) |
|
probably null |
Het |
| Kif17 |
T |
C |
4: 138,025,542 (GRCm39) |
M948T |
possibly damaging |
Het |
| Klhl33 |
A |
T |
14: 51,129,583 (GRCm39) |
N347K |
probably damaging |
Het |
| Llph |
T |
A |
10: 120,064,086 (GRCm39) |
C67* |
probably null |
Het |
| Lrrn3 |
T |
C |
12: 41,504,033 (GRCm39) |
T95A |
probably damaging |
Het |
| Map3k12 |
C |
A |
15: 102,410,613 (GRCm39) |
A455S |
probably damaging |
Het |
| Mex3d |
T |
C |
10: 80,217,376 (GRCm39) |
T149A |
probably benign |
Het |
| Myo7b |
A |
G |
18: 32,133,123 (GRCm39) |
W409R |
probably damaging |
Het |
| Nbea |
A |
G |
3: 55,916,761 (GRCm39) |
M833T |
possibly damaging |
Het |
| Ncapg |
A |
G |
5: 45,837,236 (GRCm39) |
T436A |
probably null |
Het |
| Nkx1-2 |
C |
A |
7: 132,201,042 (GRCm39) |
D72Y |
probably null |
Het |
| Or11g27 |
T |
C |
14: 50,771,159 (GRCm39) |
S97P |
possibly damaging |
Het |
| Or2d3b |
T |
A |
7: 106,514,317 (GRCm39) |
I304K |
probably benign |
Het |
| Or6c217 |
T |
A |
10: 129,737,751 (GRCm39) |
N276I |
probably damaging |
Het |
| Pcdh15 |
A |
G |
10: 74,460,087 (GRCm39) |
Y1308C |
probably damaging |
Het |
| Pcnx2 |
A |
G |
8: 126,613,665 (GRCm39) |
|
probably benign |
Het |
| Pcsk1 |
G |
A |
13: 75,246,096 (GRCm39) |
G158D |
probably damaging |
Het |
| Phkb |
A |
T |
8: 86,744,070 (GRCm39) |
D573V |
probably damaging |
Het |
| Pik3r4 |
A |
G |
9: 105,544,970 (GRCm39) |
K150E |
possibly damaging |
Het |
| Ppp2r5e |
C |
G |
12: 75,516,341 (GRCm39) |
A239P |
probably damaging |
Het |
| Ppp4r4 |
C |
T |
12: 103,566,754 (GRCm39) |
A67V |
probably damaging |
Het |
| Prex2 |
A |
G |
1: 11,252,122 (GRCm39) |
T1056A |
probably benign |
Het |
| Prkca |
A |
T |
11: 107,903,518 (GRCm39) |
Y285N |
possibly damaging |
Het |
| Psd |
T |
C |
19: 46,301,880 (GRCm39) |
E903G |
probably damaging |
Het |
| Psg19 |
T |
C |
7: 18,527,987 (GRCm39) |
E252G |
probably benign |
Het |
| Psg20 |
T |
A |
7: 18,414,969 (GRCm39) |
K306* |
probably null |
Het |
| Pygl |
T |
G |
12: 70,241,148 (GRCm39) |
|
probably benign |
Het |
| Rasgrf2 |
A |
G |
13: 92,130,890 (GRCm39) |
S724P |
probably damaging |
Het |
| Reck |
C |
A |
4: 43,922,967 (GRCm39) |
A414D |
probably damaging |
Het |
| Scn10a |
C |
A |
9: 119,459,213 (GRCm39) |
V1150L |
probably damaging |
Het |
| Shc2 |
A |
T |
10: 79,465,751 (GRCm39) |
I187N |
probably damaging |
Het |
| Sipa1l3 |
T |
A |
7: 29,086,716 (GRCm39) |
K625* |
probably null |
Het |
| Slc44a4 |
T |
C |
17: 35,147,466 (GRCm39) |
L583P |
possibly damaging |
Het |
| Slc5a11 |
G |
C |
7: 122,857,643 (GRCm39) |
R244P |
possibly damaging |
Het |
| Slfn8 |
T |
A |
11: 82,894,407 (GRCm39) |
Q744L |
probably benign |
Het |
| Snx2 |
G |
T |
18: 53,309,488 (GRCm39) |
V13L |
probably benign |
Het |
| Spmip5 |
A |
T |
19: 58,776,015 (GRCm39) |
L138Q |
probably damaging |
Het |
| Spsb1 |
C |
T |
4: 149,990,872 (GRCm39) |
|
probably null |
Het |
| Stfa2l1 |
A |
T |
16: 35,977,228 (GRCm39) |
I8L |
probably benign |
Het |
| Svil |
G |
T |
18: 5,097,494 (GRCm39) |
R1659L |
probably damaging |
Het |
| Tbccd1 |
A |
T |
16: 22,640,995 (GRCm39) |
L461M |
probably benign |
Het |
| Tmem9 |
A |
T |
1: 135,961,926 (GRCm39) |
T174S |
possibly damaging |
Het |
| Tnks2 |
T |
C |
19: 36,867,450 (GRCm39) |
|
probably null |
Het |
| Tnrc18 |
C |
A |
5: 142,800,869 (GRCm39) |
V30L |
probably benign |
Het |
| Tomm7 |
A |
G |
5: 24,049,025 (GRCm39) |
F16S |
probably damaging |
Het |
| Ttf2 |
A |
G |
3: 100,876,865 (GRCm39) |
|
probably benign |
Het |
| Ubr7 |
C |
A |
12: 102,735,450 (GRCm39) |
T303N |
probably damaging |
Het |
| Ushbp1 |
A |
T |
8: 71,842,868 (GRCm39) |
|
probably null |
Het |
| Vmn1r177 |
C |
A |
7: 23,565,475 (GRCm39) |
V134F |
probably benign |
Het |
| Vmn2r12 |
A |
G |
5: 109,235,716 (GRCm39) |
|
probably null |
Het |
| Vmn2r53 |
T |
G |
7: 12,335,141 (GRCm39) |
H173P |
probably benign |
Het |
| Yars1 |
A |
T |
4: 129,090,948 (GRCm39) |
M119L |
probably damaging |
Het |
| Zcrb1 |
A |
T |
15: 93,295,038 (GRCm39) |
|
probably benign |
Het |
| Zfp267 |
T |
A |
3: 36,218,935 (GRCm39) |
Y319* |
probably null |
Het |
| Zfp319 |
C |
A |
8: 96,056,250 (GRCm39) |
|
probably benign |
Het |
| Zfp783 |
C |
G |
6: 47,920,320 (GRCm39) |
|
noncoding transcript |
Het |
| Zfyve26 |
A |
G |
12: 79,320,372 (GRCm39) |
I1024T |
possibly damaging |
Het |
|
| Other mutations in Abca8a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:Abca8a
|
APN |
11 |
109,941,765 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
IGL01099:Abca8a
|
APN |
11 |
109,965,031 (GRCm39) |
splice site |
probably benign |
|
|
IGL01100:Abca8a
|
APN |
11 |
109,949,249 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01310:Abca8a
|
APN |
11 |
109,950,801 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01357:Abca8a
|
APN |
11 |
109,922,398 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01554:Abca8a
|
APN |
11 |
109,932,992 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL01937:Abca8a
|
APN |
11 |
109,974,130 (GRCm39) |
splice site |
probably benign |
|
|
IGL01945:Abca8a
|
APN |
11 |
109,974,130 (GRCm39) |
splice site |
probably benign |
|
|
IGL01987:Abca8a
|
APN |
11 |
109,964,981 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
IGL02023:Abca8a
|
APN |
11 |
109,953,942 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02208:Abca8a
|
APN |
11 |
109,950,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02378:Abca8a
|
APN |
11 |
109,969,641 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02380:Abca8a
|
APN |
11 |
109,969,641 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02387:Abca8a
|
APN |
11 |
109,969,641 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02388:Abca8a
|
APN |
11 |
109,969,641 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02524:Abca8a
|
APN |
11 |
109,969,641 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02551:Abca8a
|
APN |
11 |
109,975,068 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02831:Abca8a
|
APN |
11 |
109,943,907 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02836:Abca8a
|
APN |
11 |
109,961,177 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02934:Abca8a
|
APN |
11 |
109,931,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02946:Abca8a
|
APN |
11 |
109,919,041 (GRCm39) |
splice site |
probably benign |
|
|
IGL02967:Abca8a
|
APN |
11 |
109,941,762 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02997:Abca8a
|
APN |
11 |
109,966,359 (GRCm39) |
splice site |
probably benign |
|
|
IGL03265:Abca8a
|
APN |
11 |
109,943,929 (GRCm39) |
missense |
probably benign |
0.01 |
|
G5030:Abca8a
|
UTSW |
11 |
109,961,165 (GRCm39) |
missense |
probably damaging |
1.00 |
|
H8562:Abca8a
|
UTSW |
11 |
109,933,835 (GRCm39) |
missense |
probably benign |
|
|
PIT4445001:Abca8a
|
UTSW |
11 |
109,966,377 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0060:Abca8a
|
UTSW |
11 |
109,961,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0060:Abca8a
|
UTSW |
11 |
109,961,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0084:Abca8a
|
UTSW |
11 |
109,927,423 (GRCm39) |
splice site |
probably benign |
|
|
R0394:Abca8a
|
UTSW |
11 |
109,917,169 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0477:Abca8a
|
UTSW |
11 |
109,956,051 (GRCm39) |
missense |
probably benign |
|
|
R0593:Abca8a
|
UTSW |
11 |
109,958,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0744:Abca8a
|
UTSW |
11 |
109,931,390 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0764:Abca8a
|
UTSW |
11 |
109,950,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0787:Abca8a
|
UTSW |
11 |
109,933,814 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R0836:Abca8a
|
UTSW |
11 |
109,931,390 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0848:Abca8a
|
UTSW |
11 |
109,919,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1163:Abca8a
|
UTSW |
11 |
109,962,356 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1224:Abca8a
|
UTSW |
11 |
109,931,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1474:Abca8a
|
UTSW |
11 |
109,960,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1596:Abca8a
|
UTSW |
11 |
109,958,886 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1708:Abca8a
|
UTSW |
11 |
109,943,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1715:Abca8a
|
UTSW |
11 |
109,982,406 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1795:Abca8a
|
UTSW |
11 |
109,941,792 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1832:Abca8a
|
UTSW |
11 |
109,962,277 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1852:Abca8a
|
UTSW |
11 |
109,960,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1887:Abca8a
|
UTSW |
11 |
109,980,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1891:Abca8a
|
UTSW |
11 |
109,982,433 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1917:Abca8a
|
UTSW |
11 |
109,982,341 (GRCm39) |
splice site |
probably benign |
|
|
R1943:Abca8a
|
UTSW |
11 |
109,960,689 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1962:Abca8a
|
UTSW |
11 |
109,917,731 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R2016:Abca8a
|
UTSW |
11 |
109,961,213 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2037:Abca8a
|
UTSW |
11 |
109,980,810 (GRCm39) |
splice site |
probably null |
|
|
R2098:Abca8a
|
UTSW |
11 |
109,927,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2102:Abca8a
|
UTSW |
11 |
109,958,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2134:Abca8a
|
UTSW |
11 |
109,921,743 (GRCm39) |
missense |
probably null |
1.00 |
|
R2220:Abca8a
|
UTSW |
11 |
109,917,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2269:Abca8a
|
UTSW |
11 |
109,917,718 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2395:Abca8a
|
UTSW |
11 |
109,959,614 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2847:Abca8a
|
UTSW |
11 |
109,932,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2849:Abca8a
|
UTSW |
11 |
109,932,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3508:Abca8a
|
UTSW |
11 |
109,953,991 (GRCm39) |
missense |
probably benign |
|
|
R3974:Abca8a
|
UTSW |
11 |
109,974,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4009:Abca8a
|
UTSW |
11 |
109,980,933 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4163:Abca8a
|
UTSW |
11 |
109,941,808 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4274:Abca8a
|
UTSW |
11 |
109,980,930 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4507:Abca8a
|
UTSW |
11 |
109,953,851 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4571:Abca8a
|
UTSW |
11 |
109,920,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4672:Abca8a
|
UTSW |
11 |
109,962,702 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4700:Abca8a
|
UTSW |
11 |
109,961,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4770:Abca8a
|
UTSW |
11 |
109,962,341 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4946:Abca8a
|
UTSW |
11 |
109,977,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4955:Abca8a
|
UTSW |
11 |
109,927,338 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5186:Abca8a
|
UTSW |
11 |
109,982,425 (GRCm39) |
missense |
probably null |
0.31 |
|
R5190:Abca8a
|
UTSW |
11 |
109,980,735 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5597:Abca8a
|
UTSW |
11 |
109,927,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5677:Abca8a
|
UTSW |
11 |
109,929,225 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5757:Abca8a
|
UTSW |
11 |
109,933,794 (GRCm39) |
missense |
probably benign |
0.28 |
|
R5822:Abca8a
|
UTSW |
11 |
109,921,705 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5925:Abca8a
|
UTSW |
11 |
109,948,049 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6090:Abca8a
|
UTSW |
11 |
109,954,048 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6122:Abca8a
|
UTSW |
11 |
109,961,249 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6189:Abca8a
|
UTSW |
11 |
109,921,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6200:Abca8a
|
UTSW |
11 |
109,980,876 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6374:Abca8a
|
UTSW |
11 |
109,974,216 (GRCm39) |
nonsense |
probably null |
|
|
R7022:Abca8a
|
UTSW |
11 |
109,974,326 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7161:Abca8a
|
UTSW |
11 |
109,964,968 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7198:Abca8a
|
UTSW |
11 |
109,969,481 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7220:Abca8a
|
UTSW |
11 |
109,980,793 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7290:Abca8a
|
UTSW |
11 |
109,921,714 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7381:Abca8a
|
UTSW |
11 |
109,920,913 (GRCm39) |
splice site |
probably null |
|
|
R7437:Abca8a
|
UTSW |
11 |
109,941,790 (GRCm39) |
missense |
probably benign |
|
|
R7733:Abca8a
|
UTSW |
11 |
109,945,413 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7785:Abca8a
|
UTSW |
11 |
109,965,032 (GRCm39) |
splice site |
probably null |
|
|
R7917:Abca8a
|
UTSW |
11 |
109,958,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7948:Abca8a
|
UTSW |
11 |
109,941,805 (GRCm39) |
missense |
probably benign |
|
|
R7957:Abca8a
|
UTSW |
11 |
109,982,439 (GRCm39) |
start codon destroyed |
probably null |
1.00 |
|
R7958:Abca8a
|
UTSW |
11 |
109,922,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7981:Abca8a
|
UTSW |
11 |
109,980,739 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8033:Abca8a
|
UTSW |
11 |
109,927,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8069:Abca8a
|
UTSW |
11 |
109,980,876 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8116:Abca8a
|
UTSW |
11 |
109,982,420 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8289:Abca8a
|
UTSW |
11 |
109,927,515 (GRCm39) |
intron |
probably benign |
|
|
R8334:Abca8a
|
UTSW |
11 |
109,959,650 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8371:Abca8a
|
UTSW |
11 |
109,945,473 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8406:Abca8a
|
UTSW |
11 |
109,977,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8438:Abca8a
|
UTSW |
11 |
109,966,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8670:Abca8a
|
UTSW |
11 |
109,966,424 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8807:Abca8a
|
UTSW |
11 |
109,974,252 (GRCm39) |
missense |
probably benign |
0.35 |
|
R8821:Abca8a
|
UTSW |
11 |
109,949,362 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8838:Abca8a
|
UTSW |
11 |
109,920,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8884:Abca8a
|
UTSW |
11 |
109,964,941 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R8885:Abca8a
|
UTSW |
11 |
109,960,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8962:Abca8a
|
UTSW |
11 |
109,969,634 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8966:Abca8a
|
UTSW |
11 |
109,962,245 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9272:Abca8a
|
UTSW |
11 |
109,953,908 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9331:Abca8a
|
UTSW |
11 |
109,917,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9397:Abca8a
|
UTSW |
11 |
109,921,173 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9498:Abca8a
|
UTSW |
11 |
109,977,374 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9529:Abca8a
|
UTSW |
11 |
109,947,167 (GRCm39) |
nonsense |
probably null |
|
|
R9564:Abca8a
|
UTSW |
11 |
109,965,010 (GRCm39) |
missense |
probably benign |
0.04 |
|
X0022:Abca8a
|
UTSW |
11 |
109,921,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0024:Abca8a
|
UTSW |
11 |
109,974,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0053:Abca8a
|
UTSW |
11 |
109,974,310 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
|
| Posted On |
2013-11-08 |
Incidental Mutation