Incidental Mutation 'R0966:Gm10110'
ID |
84064 |
Institutional Source |
Beutler Lab
|
Gene Symbol |
Gm10110
|
Ensembl Gene |
ENSMUSG00000062093 |
Gene Name |
predicted gene 10110 |
Synonyms |
|
MMRRC Submission |
039095-MU
|
Accession Numbers |
|
Essential gene? |
Probably non essential
(E-score: 0.184)
|
Stock # |
R0966 (G1)
|
Quality Score |
109 |
Status
|
Not validated
|
Chromosome |
14 |
Chromosomal Location |
90133664-90136883 bp(-) (GRCm39) |
Type of Mutation |
exon |
DNA Base Change (assembly) |
A to C
at 90135555 bp (GRCm39)
|
Zygosity |
Heterozygous |
Amino Acid Change |
|
Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000081204]
|
AlphaFold |
no structure available at present |
Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000081204
|
SMART Domains |
Protein: ENSMUSP00000079967 Gene: ENSMUSG00000062093
Domain | Start | End | E-Value | Type |
RRM
|
12 |
85 |
1.47e-21 |
SMART |
RRM
|
100 |
171 |
2.91e-25 |
SMART |
RRM
|
192 |
264 |
1.27e-25 |
SMART |
RRM
|
295 |
366 |
1.92e-25 |
SMART |
low complexity region
|
478 |
493 |
N/A |
INTRINSIC |
low complexity region
|
503 |
516 |
N/A |
INTRINSIC |
PolyA
|
534 |
597 |
4.49e-41 |
SMART |
|
Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000228705
|
Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 96.8%
- 20x: 94.0%
|
Validation Efficiency |
|
Allele List at MGI |
|
Other mutations in this stock |
Total: 19 list
Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
2310061N02Rik |
T |
A |
16: 88,504,310 (GRCm39) |
R162S |
probably damaging |
Het |
Arhgef10 |
T |
G |
8: 14,990,343 (GRCm39) |
S272A |
probably benign |
Het |
Cd101 |
A |
C |
3: 100,915,538 (GRCm39) |
S676R |
probably benign |
Het |
Efcab5 |
G |
A |
11: 77,031,749 (GRCm39) |
R42W |
probably damaging |
Het |
Flrt2 |
T |
C |
12: 95,747,075 (GRCm39) |
V471A |
possibly damaging |
Het |
Fzd8 |
A |
T |
18: 9,214,745 (GRCm39) |
E609V |
probably damaging |
Het |
Hsh2d |
G |
A |
8: 72,954,304 (GRCm39) |
D229N |
probably benign |
Het |
Igf2bp2 |
C |
T |
16: 21,907,840 (GRCm39) |
R19Q |
probably damaging |
Het |
Mmp16 |
C |
G |
4: 18,115,930 (GRCm39) |
N511K |
probably benign |
Het |
Myo7b |
T |
C |
18: 32,131,816 (GRCm39) |
H460R |
probably damaging |
Het |
Or52a5 |
T |
A |
7: 103,426,656 (GRCm39) |
T299S |
probably damaging |
Het |
Plekhh1 |
T |
C |
12: 79,112,504 (GRCm39) |
F594L |
probably damaging |
Het |
Prkca |
T |
A |
11: 107,905,110 (GRCm39) |
K209N |
possibly damaging |
Het |
Slc5a2 |
G |
C |
7: 127,869,803 (GRCm39) |
R412P |
probably damaging |
Het |
Slco1a7 |
A |
G |
6: 141,673,299 (GRCm39) |
F413S |
probably benign |
Het |
Ugt1a6b |
G |
A |
1: 88,034,850 (GRCm39) |
V63I |
probably benign |
Het |
Ugt2b38 |
T |
G |
5: 87,560,232 (GRCm39) |
N361H |
probably damaging |
Het |
Vps36 |
G |
A |
8: 22,696,833 (GRCm39) |
W131* |
probably null |
Het |
Wdr3 |
A |
T |
3: 100,068,385 (GRCm39) |
V41E |
probably damaging |
Het |
|
Other mutations in Gm10110 |
Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
IGL01390:Gm10110
|
APN |
14 |
90,135,677 (GRCm39) |
exon |
noncoding transcript |
|
IGL02308:Gm10110
|
APN |
14 |
90,135,031 (GRCm39) |
exon |
noncoding transcript |
|
IGL02977:Gm10110
|
APN |
14 |
90,134,768 (GRCm39) |
exon |
noncoding transcript |
|
IGL03230:Gm10110
|
APN |
14 |
90,135,733 (GRCm39) |
exon |
noncoding transcript |
|
R1466:Gm10110
|
UTSW |
14 |
90,135,511 (GRCm39) |
exon |
noncoding transcript |
|
R1466:Gm10110
|
UTSW |
14 |
90,135,511 (GRCm39) |
exon |
noncoding transcript |
|
R1640:Gm10110
|
UTSW |
14 |
90,135,679 (GRCm39) |
exon |
noncoding transcript |
|
R1762:Gm10110
|
UTSW |
14 |
90,134,825 (GRCm39) |
exon |
noncoding transcript |
|
R1839:Gm10110
|
UTSW |
14 |
90,135,272 (GRCm39) |
exon |
noncoding transcript |
|
R2679:Gm10110
|
UTSW |
14 |
90,134,852 (GRCm39) |
exon |
noncoding transcript |
|
R3907:Gm10110
|
UTSW |
14 |
90,135,583 (GRCm39) |
exon |
noncoding transcript |
|
R4512:Gm10110
|
UTSW |
14 |
90,135,151 (GRCm39) |
exon |
noncoding transcript |
|
R4513:Gm10110
|
UTSW |
14 |
90,135,151 (GRCm39) |
exon |
noncoding transcript |
|
R4590:Gm10110
|
UTSW |
14 |
90,134,982 (GRCm39) |
exon |
noncoding transcript |
|
R4877:Gm10110
|
UTSW |
14 |
90,134,785 (GRCm39) |
exon |
noncoding transcript |
|
R5771:Gm10110
|
UTSW |
14 |
90,134,675 (GRCm39) |
exon |
noncoding transcript |
|
R6333:Gm10110
|
UTSW |
14 |
90,135,733 (GRCm39) |
exon |
noncoding transcript |
|
R6341:Gm10110
|
UTSW |
14 |
90,134,144 (GRCm39) |
exon |
noncoding transcript |
|
R8235:Gm10110
|
UTSW |
14 |
90,135,677 (GRCm39) |
missense |
noncoding transcript |
|
R8236:Gm10110
|
UTSW |
14 |
90,135,677 (GRCm39) |
missense |
noncoding transcript |
|
R8237:Gm10110
|
UTSW |
14 |
90,135,677 (GRCm39) |
missense |
noncoding transcript |
|
R8281:Gm10110
|
UTSW |
14 |
90,135,677 (GRCm39) |
missense |
noncoding transcript |
|
R8282:Gm10110
|
UTSW |
14 |
90,135,677 (GRCm39) |
missense |
noncoding transcript |
|
R8283:Gm10110
|
UTSW |
14 |
90,135,677 (GRCm39) |
missense |
noncoding transcript |
|
|
Predicted Primers |
PCR Primer
(F):5'- GCGAGACTTGAATCTACCCACGAAC -3'
(R):5'- CACCGAAGCCATGCTGTATGAAAAG -3'
Sequencing Primer
(F):5'- CACGAACACTTTACGGTCATTGAG -3'
(R):5'- GCTGTATGAAAAGTTTAGCCCTGC -3'
|
Posted On |
2013-11-08 |