Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01450:Stpg3'

84621

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Stpg3

Ensembl Gene

ENSMUSG00000036770

Gene Name

sperm tail PG rich repeat containing 3

Synonyms

4933433C11Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.052) question?

Stock #

IGL01450

Quality Score

Status

Chromosome

Chromosomal Location

25102219-25104649 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to C at 25104622 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s): [ENSMUST00000028346] [ENSMUST00000043774] [ENSMUST00000059849] [ENSMUST00000114363]

AlphaFold

A2RSX4

Predicted Effect

probably benign
Transcript: ENSMUST00000028346

SMART Domains

Protein: ENSMUSP00000028346
Gene: ENSMUSG00000026969

Domain	Start	End	E-Value	Type
Pfam:DUF2475	13	71	8.1e-16	PFAM
low complexity region	130	139	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000043774

SMART Domains

Protein: ENSMUSP00000037603
Gene: ENSMUSG00000036770

Domain	Start	End	E-Value	Type
Pfam:SHIPPO-rpt	103	145	9.5e-4	PFAM
Pfam:SHIPPO-rpt	226	255	1.4e-3	PFAM
Pfam:SHIPPO-rpt	265	291	1.4e-3	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000059849

SMART Domains

Protein: ENSMUSP00000057731
Gene: ENSMUSG00000013465

Domain	Start	End	E-Value	Type
Pfam:COBRA1	107	578	3.5e-248	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000114363

SMART Domains

Protein: ENSMUSP00000110003
Gene: ENSMUSG00000036770

Domain	Start	End	E-Value	Type
Pfam:SHIPPO-rpt	48	79	2.8e-4	PFAM
Pfam:SHIPPO-rpt	110	136	1.2e-1	PFAM
Pfam:SHIPPO-rpt	152	200	3.5e-1	PFAM
Pfam:SHIPPO-rpt	210	248	1.9e-3	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000124661

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000128876

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000138199

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000147890

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000149509

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000155706

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000205741

Predicted Effect

probably benign
Transcript: ENSMUST00000140934

SMART Domains

Protein: ENSMUSP00000115698
Gene: ENSMUSG00000013465

Domain	Start	End	E-Value	Type
Pfam:COBRA1	40	204	9.7e-106	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acod1	G	A	14: 103,288,919 (GRCm39)	R143Q	possibly damaging	Het
Adh4	T	A	3: 138,129,794 (GRCm39)	C207S	probably benign	Het
Akap8	C	A	17: 32,534,661 (GRCm39)	R317L	probably damaging	Het
Aptx	T	C	4: 40,688,133 (GRCm39)	T182A	probably damaging	Het
Ccar2	A	T	14: 70,377,200 (GRCm39)		probably benign	Het
Cd300ld2	T	A	11: 114,903,369 (GRCm39)		probably benign	Het
Cgnl1	T	C	9: 71,539,144 (GRCm39)		probably benign	Het
Cubn	A	G	2: 13,355,673 (GRCm39)		probably benign	Het
Cyp2j5	T	A	4: 96,546,927 (GRCm39)	T196S	probably damaging	Het
Dctn1	T	C	6: 83,171,092 (GRCm39)		probably benign	Het
Dync2li1	A	T	17: 84,940,984 (GRCm39)	T67S	possibly damaging	Het
Fetub	A	G	16: 22,747,986 (GRCm39)	N54S	probably benign	Het
Gpld1	T	C	13: 25,163,664 (GRCm39)	Y486H	probably damaging	Het
Grb10	T	A	11: 11,920,432 (GRCm39)	H62L	probably damaging	Het
H6pd	T	G	4: 150,068,575 (GRCm39)	H264P	probably damaging	Het
Lmtk2	T	C	5: 144,111,520 (GRCm39)	S747P	probably benign	Het
Mtcl3	T	A	10: 29,072,319 (GRCm39)	M537K	probably damaging	Het
Nkpd1	T	C	7: 19,257,550 (GRCm39)	F293S	probably damaging	Het
Or1j15	T	A	2: 36,458,754 (GRCm39)	L48H	probably damaging	Het
Osbpl1a	A	C	18: 13,004,152 (GRCm39)	F422V	possibly damaging	Het
Pclo	A	T	5: 14,727,207 (GRCm39)		probably benign	Het
Phc3	G	A	3: 30,968,653 (GRCm39)	R825C	probably damaging	Het
Plk2	G	A	13: 110,532,858 (GRCm39)	V140M	probably damaging	Het
Racgap1	A	G	15: 99,524,244 (GRCm39)	S388P	probably benign	Het
Rap1gds1	A	T	3: 138,671,681 (GRCm39)	N146K	probably damaging	Het
Rgs7	C	T	1: 174,913,746 (GRCm39)	V1M	probably benign	Het
Rps6ka5	A	T	12: 100,519,250 (GRCm39)		probably benign	Het
Scn4a	A	G	11: 106,215,487 (GRCm39)	I1163T	probably damaging	Het
Selenop	C	T	15: 3,306,755 (GRCm39)	T178M	probably benign	Het
Shank2	G	T	7: 143,838,805 (GRCm39)	E680*	probably null	Het
Sipa1l2	A	C	8: 126,149,316 (GRCm39)		probably null	Het
Slc14a2	T	C	18: 78,226,745 (GRCm39)	T437A	probably damaging	Het
Smarcc2	C	T	10: 128,305,189 (GRCm39)	P307S	probably damaging	Het
Sptb	C	A	12: 76,671,014 (GRCm39)	R443L	possibly damaging	Het
Tinag	T	A	9: 76,952,858 (GRCm39)	E42V	possibly damaging	Het
Topors	C	A	4: 40,262,417 (GRCm39)	R289L	probably damaging	Het
Ubash3a	C	A	17: 31,427,205 (GRCm39)	A38E	probably damaging	Het
Vmn2r121	T	A	X: 123,040,888 (GRCm39)	Y481F	possibly damaging	Het
Vps54	A	T	11: 21,241,135 (GRCm39)	E359D	probably benign	Het
Xkr6	G	A	14: 64,035,664 (GRCm39)	R255H	probably damaging	Het
Zfp750	C	T	11: 121,403,855 (GRCm39)	R340H	probably benign	Het

Other mutations in Stpg3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01116:Stpg3	APN	2	25,103,191 (GRCm39)	unclassified	probably benign
R1413:Stpg3	UTSW	2	25,103,862 (GRCm39)	missense	probably damaging	1.00
R1612:Stpg3	UTSW	2	25,103,866 (GRCm39)	missense	probably benign	0.00
R3780:Stpg3	UTSW	2	25,103,875 (GRCm39)	missense	probably benign	0.00
R3781:Stpg3	UTSW	2	25,103,875 (GRCm39)	missense	probably benign	0.00
R4694:Stpg3	UTSW	2	25,103,309 (GRCm39)	missense	probably damaging	0.96
R5029:Stpg3	UTSW	2	25,104,576 (GRCm39)	missense	probably damaging	0.97
R5406:Stpg3	UTSW	2	25,103,580 (GRCm39)	nonsense	probably null
R7202:Stpg3	UTSW	2	25,104,586 (GRCm39)	missense	probably damaging	1.00
R8458:Stpg3	UTSW	2	25,103,333 (GRCm39)	missense	probably damaging	1.00
R9476:Stpg3	UTSW	2	25,103,516 (GRCm39)	missense	probably benign	0.00
R9510:Stpg3	UTSW	2	25,103,516 (GRCm39)	missense	probably benign	0.00

Posted On

2013-11-11