Incidental Mutation 'IGL01456:Vmn1r177'
| ID |
84775 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r177
|
| Ensembl Gene |
ENSMUSG00000057513 |
| Gene Name |
vomeronasal 1 receptor 177 |
| Synonyms |
V1rd12 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.070)
|
| Stock # |
IGL01456
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
23564945-23565874 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 23565753 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Glutamine
at position 41
(P41Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000073621
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000073967]
|
| AlphaFold |
E9PXM3 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000073967
AA Change: P41Q
PolyPhen 2
Score 0.579 (Sensitivity: 0.88; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000073621
Gene: ENSMUSG00000057513
AA Change: P41Q
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
8 |
299 |
4.1e-13 |
PFAM |
|
Pfam:V1R
|
41 |
297 |
5.3e-14 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000207027
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 32 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam6b |
T |
A |
12: 113,455,083 (GRCm39) |
D633E |
probably benign |
Het |
| Akap13 |
T |
C |
7: 75,252,595 (GRCm39) |
C242R |
probably damaging |
Het |
| Ap5z1 |
T |
C |
5: 142,453,791 (GRCm39) |
L175P |
probably damaging |
Het |
| Arid1b |
A |
G |
17: 5,341,510 (GRCm39) |
E938G |
probably damaging |
Het |
| Arid4a |
A |
G |
12: 71,114,036 (GRCm39) |
N208D |
probably benign |
Het |
| Atr |
A |
G |
9: 95,832,618 (GRCm39) |
H2556R |
possibly damaging |
Het |
| Cald1 |
A |
T |
6: 34,741,931 (GRCm39) |
D438V |
probably damaging |
Het |
| Dcbld2 |
C |
T |
16: 58,229,236 (GRCm39) |
P40S |
possibly damaging |
Het |
| Dock8 |
G |
A |
19: 25,096,863 (GRCm39) |
M590I |
possibly damaging |
Het |
| Gm1818 |
A |
T |
12: 48,602,583 (GRCm39) |
|
noncoding transcript |
Het |
| Hace1 |
A |
G |
10: 45,586,094 (GRCm39) |
|
probably benign |
Het |
| Igkv10-96 |
A |
G |
6: 68,609,086 (GRCm39) |
Y70H |
probably benign |
Het |
| Kdm2a |
G |
T |
19: 4,401,783 (GRCm39) |
H200Q |
probably damaging |
Het |
| Ldha |
A |
G |
7: 46,499,602 (GRCm39) |
D111G |
possibly damaging |
Het |
| Map7 |
A |
G |
10: 20,149,550 (GRCm39) |
E567G |
unknown |
Het |
| Nbeal1 |
G |
T |
1: 60,269,787 (GRCm39) |
L375F |
probably damaging |
Het |
| Nectin3 |
T |
C |
16: 46,279,216 (GRCm39) |
E254G |
probably benign |
Het |
| Nlrp4b |
A |
T |
7: 10,448,150 (GRCm39) |
I118F |
probably benign |
Het |
| Pkhd1 |
A |
T |
1: 20,269,683 (GRCm39) |
V3287D |
probably damaging |
Het |
| Ptpre |
T |
G |
7: 135,271,531 (GRCm39) |
V375G |
probably damaging |
Het |
| Rabgap1 |
A |
G |
2: 37,431,187 (GRCm39) |
E746G |
probably damaging |
Het |
| Sh2b2 |
C |
T |
5: 136,253,321 (GRCm39) |
C311Y |
probably damaging |
Het |
| Skor1 |
G |
A |
9: 63,052,772 (GRCm39) |
T399I |
probably damaging |
Het |
| Sptbn2 |
A |
G |
19: 4,796,777 (GRCm39) |
T1792A |
probably damaging |
Het |
| Tiparp |
G |
T |
3: 65,460,030 (GRCm39) |
G442* |
probably null |
Het |
| Tln1 |
G |
A |
4: 43,543,432 (GRCm39) |
|
probably benign |
Het |
| Tmc7 |
C |
A |
7: 118,146,533 (GRCm39) |
|
probably benign |
Het |
| Top2a |
A |
T |
11: 98,901,856 (GRCm39) |
L458Q |
probably damaging |
Het |
| Tpte |
A |
G |
8: 22,835,068 (GRCm39) |
|
probably benign |
Het |
| Unc13a |
G |
A |
8: 72,097,211 (GRCm39) |
R1228W |
probably damaging |
Het |
| Vipr1 |
C |
T |
9: 121,494,244 (GRCm39) |
T275M |
probably damaging |
Het |
| Vmn2r4 |
A |
T |
3: 64,313,816 (GRCm39) |
N388K |
probably damaging |
Het |
|
| Other mutations in Vmn1r177 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01504:Vmn1r177
|
APN |
7 |
23,565,835 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01535:Vmn1r177
|
APN |
7 |
23,565,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01551:Vmn1r177
|
APN |
7 |
23,565,688 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01647:Vmn1r177
|
APN |
7 |
23,565,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ANU74:Vmn1r177
|
UTSW |
7 |
23,565,645 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0396:Vmn1r177
|
UTSW |
7 |
23,565,022 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0894:Vmn1r177
|
UTSW |
7 |
23,565,475 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1446:Vmn1r177
|
UTSW |
7 |
23,565,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1835:Vmn1r177
|
UTSW |
7 |
23,565,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1893:Vmn1r177
|
UTSW |
7 |
23,565,573 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1995:Vmn1r177
|
UTSW |
7 |
23,565,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2206:Vmn1r177
|
UTSW |
7 |
23,565,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3889:Vmn1r177
|
UTSW |
7 |
23,565,289 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4458:Vmn1r177
|
UTSW |
7 |
23,565,645 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4579:Vmn1r177
|
UTSW |
7 |
23,565,772 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5290:Vmn1r177
|
UTSW |
7 |
23,565,498 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6128:Vmn1r177
|
UTSW |
7 |
23,565,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6128:Vmn1r177
|
UTSW |
7 |
23,565,267 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6730:Vmn1r177
|
UTSW |
7 |
23,565,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6785:Vmn1r177
|
UTSW |
7 |
23,565,562 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7100:Vmn1r177
|
UTSW |
7 |
23,565,535 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7738:Vmn1r177
|
UTSW |
7 |
23,565,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8191:Vmn1r177
|
UTSW |
7 |
23,565,736 (GRCm39) |
nonsense |
probably null |
|
|
R8980:Vmn1r177
|
UTSW |
7 |
23,565,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9723:Vmn1r177
|
UTSW |
7 |
23,565,774 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9771:Vmn1r177
|
UTSW |
7 |
23,565,657 (GRCm39) |
missense |
probably damaging |
0.98 |
|
X0020:Vmn1r177
|
UTSW |
7 |
23,565,718 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Vmn1r177
|
UTSW |
7 |
23,565,360 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Posted On |
2013-11-11 |
Incidental Mutation