Incidental Mutation 'IGL01470:Zfp551'
ID88262
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zfp551
Ensembl Gene ENSMUSG00000034071
Gene Namezinc fingr protein 551
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.096) question?
Stock #IGL01470
Quality Score
Status
Chromosome7
Chromosomal Location12415153-12422751 bp(-) (GRCm38)
Type of Mutationcritical splice donor site (2 bp from exon)
DNA Base Change (assembly) A to G at 12418541 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000079222 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000080348] [ENSMUST00000120220]
Predicted Effect probably null
Transcript: ENSMUST00000080348
SMART Domains Protein: ENSMUSP00000079222
Gene: ENSMUSG00000034071

DomainStartEndE-ValueType
KRAB 48 109 2.3e-14 SMART
ZnF_C2H2 337 359 2.57e-3 SMART
ZnF_C2H2 365 387 1.47e-3 SMART
ZnF_C2H2 393 415 3.69e-4 SMART
ZnF_C2H2 421 443 1.22e-4 SMART
ZnF_C2H2 449 471 3.11e-2 SMART
ZnF_C2H2 477 499 3.44e-4 SMART
ZnF_C2H2 505 527 9.73e-4 SMART
ZnF_C2H2 533 555 1.6e-4 SMART
ZnF_C2H2 561 583 1.38e-3 SMART
ZnF_C2H2 589 611 8.47e-4 SMART
ZnF_C2H2 617 639 6.99e-5 SMART
ZnF_C2H2 645 667 2.09e-3 SMART
ZnF_C2H2 673 695 1.98e-4 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000120220
Predicted Effect probably benign
Transcript: ENSMUST00000123877
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
3425401B19Rik T C 14: 32,660,457 T1184A possibly damaging Het
A2ml1 A G 6: 128,580,412 I106T probably damaging Het
Asic4 C T 1: 75,450,866 A12V probably damaging Het
Cacna1d A T 14: 30,099,142 V1139D probably damaging Het
Edc4 T C 8: 105,889,981 probably benign Het
Eif4h A T 5: 134,625,539 probably null Het
Exog C A 9: 119,462,526 Q290K probably damaging Het
Fam83c A T 2: 155,834,808 I14K possibly damaging Het
Fes A T 7: 80,383,273 Y268N probably benign Het
Fhod1 A G 8: 105,329,649 L1144P probably damaging Het
Frem3 C T 8: 80,614,315 T1079I probably damaging Het
Gbp10 A G 5: 105,221,114 probably benign Het
Herc1 T C 9: 66,497,636 V4496A possibly damaging Het
Lamb1 A G 12: 31,300,262 R729G possibly damaging Het
Lifr T A 15: 7,175,666 C461* probably null Het
Lypd6 T C 2: 50,188,783 V97A probably benign Het
Map3k5 A G 10: 20,118,187 E973G possibly damaging Het
Mep1b A T 18: 21,097,467 N692I probably benign Het
Mrpl15 A G 1: 4,776,531 V274A probably damaging Het
Naaa A G 5: 92,263,648 I264T probably damaging Het
Nlrp4c T C 7: 6,100,784 C906R possibly damaging Het
Olfr1047 T C 2: 86,228,284 N229S probably benign Het
Olfr1265 T C 2: 90,037,818 W300R possibly damaging Het
Olfr1443 T C 19: 12,680,671 S188P possibly damaging Het
Olfr344 T A 2: 36,568,742 L48H probably damaging Het
Olfr885 A T 9: 38,062,004 H228L possibly damaging Het
Phc2 C T 4: 128,723,110 T392I probably benign Het
Ptprg G A 14: 12,213,702 W248* probably null Het
Pzp T A 6: 128,521,124 E243D probably benign Het
Rbm33 T A 5: 28,387,848 L542Q probably damaging Het
Recql4 G A 15: 76,708,944 T229I probably benign Het
Ssbp3 T C 4: 107,037,658 probably benign Het
Tfap2d A T 1: 19,148,396 Q373L probably damaging Het
Timmdc1 A G 16: 38,518,540 probably benign Het
Tiparp G T 3: 65,552,609 G442* probably null Het
Vmn2r4 A T 3: 64,406,395 N388K probably damaging Het
Vps13c T C 9: 67,912,927 probably benign Het
Other mutations in Zfp551
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01990:Zfp551 APN 7 12422416 missense possibly damaging 0.90
IGL02511:Zfp551 APN 7 12416675 missense possibly damaging 0.70
R2001:Zfp551 UTSW 7 12416349 missense probably damaging 1.00
R3120:Zfp551 UTSW 7 12416016 missense possibly damaging 0.94
R4256:Zfp551 UTSW 7 12416391 missense possibly damaging 0.95
R4387:Zfp551 UTSW 7 12418641 missense probably damaging 1.00
R5314:Zfp551 UTSW 7 12416160 nonsense probably null
R5536:Zfp551 UTSW 7 12415561 missense possibly damaging 0.86
R5874:Zfp551 UTSW 7 12416174 missense probably damaging 1.00
R6265:Zfp551 UTSW 7 12415412 missense probably damaging 1.00
R6765:Zfp551 UTSW 7 12416840 missense possibly damaging 0.85
R6803:Zfp551 UTSW 7 12417181 nonsense probably null
R6953:Zfp551 UTSW 7 12416788 nonsense probably null
R7334:Zfp551 UTSW 7 12416754 missense probably damaging 0.97
R7345:Zfp551 UTSW 7 12416595 missense probably benign
Posted On2013-11-18