Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01471:Ly6m'

88272

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ly6m

Ensembl Gene

ENSMUSG00000063522

Gene Name

lymphocyte antigen 6 family member M

Synonyms

2010109I03Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.062) question?

Stock #

IGL01471

Quality Score

Status

Chromosome

Chromosomal Location

74750185-74753553 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 74751749 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 95 (V95A)

Ref Sequence

ENSEMBL: ENSMUSP00000076264 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000077004]

AlphaFold

Q9CQ11

Predicted Effect

probably benign
Transcript: ENSMUST00000077004
AA Change: V95A

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000076264
Gene: ENSMUSG00000063522
AA Change: V95A

Domain	Start	End	E-Value	Type
signal peptide	1	20	N/A	INTRINSIC
LU	21	100	6.96e-5	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000190826

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 10 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Cacna1b	A	G	2: 24,547,304 (GRCm39)	S1226P	probably damaging	Het
Cdx2	A	G	5: 147,240,059 (GRCm39)	F206L	probably benign	Het
Cldn1	T	A	16: 26,190,322 (GRCm39)	I19F	possibly damaging	Het
Inpp5f	T	C	7: 128,277,122 (GRCm39)	V406A	probably damaging	Het
Myh4	C	T	11: 67,146,205 (GRCm39)	T1421M	probably damaging	Het
Pard3	A	G	8: 128,104,727 (GRCm39)	T490A	probably benign	Het
Rnf138	G	A	18: 21,157,578 (GRCm39)		probably null	Het
Slc12a4	T	C	8: 106,670,721 (GRCm39)	Y1084C	probably damaging	Het
Sppl2a	A	T	2: 126,759,787 (GRCm39)	L48*	probably null	Het
Trp53	C	A	11: 69,479,349 (GRCm39)	H173N	probably damaging	Het

Other mutations in Ly6m

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02550:Ly6m	APN	15	74,752,604 (GRCm39)	missense	probably damaging	1.00
IGL02555:Ly6m	APN	15	74,753,457 (GRCm39)	splice site	probably benign
R2905:Ly6m	UTSW	15	74,751,716 (GRCm39)	missense	probably benign
R3547:Ly6m	UTSW	15	74,753,463 (GRCm39)	missense	probably null	0.96
R4777:Ly6m	UTSW	15	74,752,532 (GRCm39)	missense	probably benign
R6432:Ly6m	UTSW	15	74,751,813 (GRCm39)	missense	probably benign	0.00

Posted On

2013-11-18