Incidental Mutation 'IGL01479:Sult6b1'
ID88546
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Sult6b1
Ensembl Gene ENSMUSG00000038045
Gene Namesulfotransferase family, cytosolic, 6B, member 1
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.204) question?
Stock #IGL01479
Quality Score
Status
Chromosome17
Chromosomal Location78883938-78906992 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 78905576 bp
ZygosityHeterozygous
Amino Acid Change Valine to Aspartic acid at position 82 (V82D)
Ref Sequence ENSEMBL: ENSMUSP00000132823 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000042683] [ENSMUST00000159710] [ENSMUST00000169544]
Predicted Effect probably benign
Transcript: ENSMUST00000042683
AA Change: V44D

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
SMART Domains Protein: ENSMUSP00000038282
Gene: ENSMUSG00000038045
AA Change: V44D

DomainStartEndE-ValueType
Pfam:Sulfotransfer_1 17 252 2.6e-57 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000159710
Predicted Effect probably benign
Transcript: ENSMUST00000169544
AA Change: V82D

PolyPhen 2 Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)
SMART Domains Protein: ENSMUSP00000132823
Gene: ENSMUSG00000038045
AA Change: V82D

DomainStartEndE-ValueType
Pfam:Sulfotransfer_1 55 290 2.1e-57 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 28 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Akr1c12 T C 13: 4,272,935 K225R probably benign Het
Amn C A 12: 111,271,793 A47E probably damaging Het
Arhgef1 T C 7: 24,912,603 I137T probably benign Het
Cep57l1 T C 10: 41,728,639 K165E possibly damaging Het
Chfr A G 5: 110,144,993 probably benign Het
Dnah9 A G 11: 65,955,717 V2923A probably benign Het
Dnaja2 T C 8: 85,553,951 Y35C probably damaging Het
Dnajc2 T C 5: 21,757,893 T481A probably damaging Het
Foxred2 A G 15: 77,952,289 probably null Het
Gin1 C T 1: 97,792,372 T364I possibly damaging Het
Glt8d2 C T 10: 82,660,736 V163I probably damaging Het
Gm10118 T C 10: 63,926,820 probably benign Het
Hps5 C T 7: 46,762,942 probably null Het
Kdm4c A G 4: 74,343,501 K638E probably benign Het
L3mbtl2 A G 15: 81,676,392 T285A probably benign Het
Mab21l1 A G 3: 55,783,832 Y280C probably damaging Het
Mcoln2 T A 3: 146,175,652 probably benign Het
Myo9b G T 8: 71,359,342 R1926L probably damaging Het
Rrp12 A G 19: 41,865,202 V1251A probably benign Het
Rtn4rl1 A G 11: 75,265,342 D200G probably damaging Het
Sbsn G A 7: 30,752,357 A266T possibly damaging Het
Sgca A T 11: 94,963,378 C335* probably null Het
Spag1 T C 15: 36,233,199 probably benign Het
Tigit T C 16: 43,659,522 T137A probably benign Het
Tmem125 G A 4: 118,541,623 Q204* probably null Het
Tmem59l C T 8: 70,486,098 R111Q probably benign Het
Vmn2r95 G A 17: 18,443,862 G448R probably damaging Het
Zfp64 T C 2: 168,951,679 H49R probably damaging Het
Other mutations in Sult6b1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02065:Sult6b1 APN 17 78889075 missense probably damaging 0.99
R0522:Sult6b1 UTSW 17 78905529 missense probably damaging 0.97
R1911:Sult6b1 UTSW 17 78888964 missense possibly damaging 0.81
R3546:Sult6b1 UTSW 17 78906907 missense probably benign 0.00
R4105:Sult6b1 UTSW 17 78906862 missense probably damaging 1.00
R4107:Sult6b1 UTSW 17 78906862 missense probably damaging 1.00
R4108:Sult6b1 UTSW 17 78906862 missense probably damaging 1.00
R5063:Sult6b1 UTSW 17 78905576 missense probably benign 0.00
R5478:Sult6b1 UTSW 17 78894672 splice site probably null
R5845:Sult6b1 UTSW 17 78894630 missense probably damaging 1.00
R6256:Sult6b1 UTSW 17 78906914 missense probably benign 0.05
R6374:Sult6b1 UTSW 17 78906931 missense probably benign 0.04
R7128:Sult6b1 UTSW 17 78894641 missense probably damaging 1.00
Posted On2013-11-18