Incidental Mutation 'IGL01480:Cd200r2'
ID88571
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Cd200r2
Ensembl Gene ENSMUSG00000090176
Gene NameCd200 receptor 2
SynonymsCD200 cell surface glycoprotein receptor isoform 2
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.069) question?
Stock #IGL01480
Quality Score
Status
Chromosome16
Chromosomal Location44867097-44915840 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 44909266 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Valine at position 95 (I95V)
Ref Sequence ENSEMBL: ENSMUSP00000099869 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000102805]
Predicted Effect probably null
Transcript: ENSMUST00000102805
AA Change: I95V

PolyPhen 2 Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
SMART Domains Protein: ENSMUSP00000099869
Gene: ENSMUSG00000090176
AA Change: I95V

DomainStartEndE-ValueType
IG 23 126 1.06e-2 SMART
IG_like 128 249 1.85e2 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 26 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adck1 T A 12: 88,456,865 C379* probably null Het
Ankrd10 A G 8: 11,635,592 V9A probably benign Het
Ankrd13a A T 5: 114,800,818 probably benign Het
Bbs1 T C 19: 4,894,393 K403E probably damaging Het
Cyba T C 8: 122,424,945 E171G probably benign Het
Dnah2 T A 11: 69,458,371 M2480L possibly damaging Het
Fxyd7 A T 7: 31,047,374 Y20* probably null Het
Il22ra1 T C 4: 135,744,801 V216A probably benign Het
Mapk10 G A 5: 102,926,152 probably benign Het
Mgat5b C A 11: 116,978,452 T607K probably benign Het
Nov A G 15: 54,752,291 Y284C probably damaging Het
Olfr344 T A 2: 36,568,742 L48H probably damaging Het
Olfr406 A T 11: 74,269,601 I71L possibly damaging Het
Olfr8 T C 10: 78,956,144 probably benign Het
Olfr975 G A 9: 39,949,988 A261V probably benign Het
Optn G A 2: 5,046,018 S184L probably benign Het
Plxna1 A G 6: 89,344,096 L462P possibly damaging Het
Prkca A G 11: 107,986,289 F339L possibly damaging Het
Prkca C T 11: 108,192,201 V73M probably damaging Het
Ptch2 T C 4: 117,114,082 V1062A probably damaging Het
Serpina11 T A 12: 103,982,851 K354* probably null Het
Sf1 T C 19: 6,372,022 probably benign Het
Stam2 A G 2: 52,716,439 S112P probably benign Het
Tlr5 G A 1: 182,973,499 E123K probably benign Het
Tpp1 T C 7: 105,749,053 E301G probably damaging Het
Vmn2r58 T A 7: 41,864,692 I176F probably benign Het
Other mutations in Cd200r2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00465:Cd200r2 APN 16 44909288 missense probably damaging 1.00
IGL01019:Cd200r2 APN 16 44909469 splice site probably benign
IGL01510:Cd200r2 APN 16 44909311 missense probably benign 0.03
IGL02202:Cd200r2 APN 16 44909360 missense probably damaging 1.00
IGL02492:Cd200r2 APN 16 44909540 missense probably damaging 1.00
IGL02499:Cd200r2 APN 16 44914585 missense possibly damaging 0.47
R0066:Cd200r2 UTSW 16 44909674 missense possibly damaging 0.94
R0066:Cd200r2 UTSW 16 44909674 missense possibly damaging 0.94
R0503:Cd200r2 UTSW 16 44877962 start codon destroyed probably null 0.93
R0526:Cd200r2 UTSW 16 44915047 missense probably damaging 1.00
R1118:Cd200r2 UTSW 16 44909606 missense probably damaging 1.00
R1119:Cd200r2 UTSW 16 44909606 missense probably damaging 1.00
R2393:Cd200r2 UTSW 16 44909267 missense probably damaging 1.00
R5450:Cd200r2 UTSW 16 44909571 missense probably benign 0.04
R7466:Cd200r2 UTSW 16 44909174 missense probably damaging 0.97
Posted On2013-11-18