Incidental Mutation 'IGL01480:Cd200r2'
| ID |
88571 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Cd200r2
|
| Ensembl Gene |
ENSMUSG00000090176 |
| Gene Name |
Cd200 receptor 2 |
| Synonyms |
CD200 cell surface glycoprotein receptor isoform 2 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.077)
|
| Stock # |
IGL01480
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
16 |
| Chromosomal Location |
44687460-44736203 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 44729629 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Valine
at position 95
(I95V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000099869
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000102805]
|
| AlphaFold |
Q6XJV6 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000102805
AA Change: I95V
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000099869
Gene: ENSMUSG00000090176
AA Change: I95V
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
23 |
126 |
1.06e-2 |
SMART |
|
IG_like
|
128 |
249 |
1.85e2 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 26 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adck1 |
T |
A |
12: 88,423,635 (GRCm39) |
C379* |
probably null |
Het |
| Ankrd10 |
A |
G |
8: 11,685,592 (GRCm39) |
V9A |
probably benign |
Het |
| Ankrd13a |
A |
T |
5: 114,938,879 (GRCm39) |
|
probably benign |
Het |
| Bbs1 |
T |
C |
19: 4,944,421 (GRCm39) |
K403E |
probably damaging |
Het |
| Ccn3 |
A |
G |
15: 54,615,687 (GRCm39) |
Y284C |
probably damaging |
Het |
| Cyba |
T |
C |
8: 123,151,684 (GRCm39) |
E171G |
probably benign |
Het |
| Dnah2 |
T |
A |
11: 69,349,197 (GRCm39) |
M2480L |
possibly damaging |
Het |
| Fxyd7 |
A |
T |
7: 30,746,799 (GRCm39) |
Y20* |
probably null |
Het |
| Il22ra1 |
T |
C |
4: 135,472,112 (GRCm39) |
V216A |
probably benign |
Het |
| Mapk10 |
G |
A |
5: 103,074,018 (GRCm39) |
|
probably benign |
Het |
| Mgat5b |
C |
A |
11: 116,869,278 (GRCm39) |
T607K |
probably benign |
Het |
| Optn |
G |
A |
2: 5,050,829 (GRCm39) |
S184L |
probably benign |
Het |
| Or10d5 |
G |
A |
9: 39,861,284 (GRCm39) |
A261V |
probably benign |
Het |
| Or1j15 |
T |
A |
2: 36,458,754 (GRCm39) |
L48H |
probably damaging |
Het |
| Or1p1c |
A |
T |
11: 74,160,427 (GRCm39) |
I71L |
possibly damaging |
Het |
| Or7a42 |
T |
C |
10: 78,791,978 (GRCm39) |
|
probably benign |
Het |
| Plxna1 |
A |
G |
6: 89,321,078 (GRCm39) |
L462P |
possibly damaging |
Het |
| Prkca |
C |
T |
11: 108,083,027 (GRCm39) |
V73M |
probably damaging |
Het |
| Prkca |
A |
G |
11: 107,877,115 (GRCm39) |
F339L |
possibly damaging |
Het |
| Ptch2 |
T |
C |
4: 116,971,279 (GRCm39) |
V1062A |
probably damaging |
Het |
| Serpina11 |
T |
A |
12: 103,949,110 (GRCm39) |
K354* |
probably null |
Het |
| Sf1 |
T |
C |
19: 6,422,052 (GRCm39) |
|
probably benign |
Het |
| Stam2 |
A |
G |
2: 52,606,451 (GRCm39) |
S112P |
probably benign |
Het |
| Tlr5 |
G |
A |
1: 182,801,064 (GRCm39) |
E123K |
probably benign |
Het |
| Tpp1 |
T |
C |
7: 105,398,260 (GRCm39) |
E301G |
probably damaging |
Het |
| Vmn2r58 |
T |
A |
7: 41,514,116 (GRCm39) |
I176F |
probably benign |
Het |
|
| Other mutations in Cd200r2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00465:Cd200r2
|
APN |
16 |
44,729,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01019:Cd200r2
|
APN |
16 |
44,729,832 (GRCm39) |
splice site |
probably benign |
|
|
IGL01510:Cd200r2
|
APN |
16 |
44,729,674 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02202:Cd200r2
|
APN |
16 |
44,729,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02492:Cd200r2
|
APN |
16 |
44,729,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02499:Cd200r2
|
APN |
16 |
44,734,948 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R0066:Cd200r2
|
UTSW |
16 |
44,730,037 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0066:Cd200r2
|
UTSW |
16 |
44,730,037 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0503:Cd200r2
|
UTSW |
16 |
44,698,325 (GRCm39) |
start codon destroyed |
probably null |
0.93 |
|
R0526:Cd200r2
|
UTSW |
16 |
44,735,410 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1118:Cd200r2
|
UTSW |
16 |
44,729,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1119:Cd200r2
|
UTSW |
16 |
44,729,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2393:Cd200r2
|
UTSW |
16 |
44,729,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5450:Cd200r2
|
UTSW |
16 |
44,729,934 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7466:Cd200r2
|
UTSW |
16 |
44,729,537 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9762:Cd200r2
|
UTSW |
16 |
44,729,420 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Posted On |
2013-11-18 |
Incidental Mutation