Incidental Mutation 'IGL01508:Pate4'
ID89106
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Pate4
Ensembl Gene ENSMUSG00000032099
Gene Nameprostate and testis expressed 4
SynonymsPate-B, Svs7, 9530004K16Rik, SVS VII
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01508
Quality Score
Status
Chromosome9
Chromosomal Location35607093-35611941 bp(-) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) A to T at 35608306 bp
ZygosityHeterozygous
Amino Acid Change Cysteine to Stop codon at position 29 (C29*)
Ref Sequence ENSEMBL: ENSMUSP00000034610 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000034610] [ENSMUST00000098906]
Predicted Effect probably null
Transcript: ENSMUST00000034610
AA Change: C29*
SMART Domains Protein: ENSMUSP00000034610
Gene: ENSMUSG00000032099
AA Change: C29*

DomainStartEndE-ValueType
signal peptide 1 23 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000098906
SMART Domains Protein: ENSMUSP00000096505
Gene: ENSMUSG00000074452

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000137309
Coding Region Coverage
Validation Efficiency
MGI Phenotype PHENOTYPE: Mice homozygous for a knockout allele do not exhibit defects in viability, bone formation or remodeling, organ gross morphology or fertility. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 31 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
A2m C T 6: 121,659,367 R732* probably null Het
Adarb2 C A 13: 8,752,570 probably null Het
Alb C T 5: 90,470,838 A430V probably benign Het
Cdhr3 A T 12: 33,053,428 F397I possibly damaging Het
Cmya5 A G 13: 93,094,027 S1518P probably benign Het
Col6a4 T A 9: 106,013,605 Y1830F possibly damaging Het
Col6a6 A G 9: 105,727,166 probably benign Het
Dnah7a T C 1: 53,627,072 S599G probably benign Het
Fbxo3 A T 2: 104,033,676 H92L probably benign Het
Ffar2 T C 7: 30,819,176 D313G probably benign Het
Fnta T C 8: 26,007,266 E185G probably damaging Het
Gdap2 C T 3: 100,170,927 T69I possibly damaging Het
Gimap7 A T 6: 48,724,296 N272I probably damaging Het
Gin1 T C 1: 97,777,437 V84A probably benign Het
Itga8 A G 2: 12,232,802 L369P possibly damaging Het
Itgax C T 7: 128,144,818 T891I probably damaging Het
Lama1 T A 17: 67,809,361 probably benign Het
Lkaaear1 T C 2: 181,697,037 T169A probably benign Het
Nckap5 A G 1: 126,025,572 V1017A probably damaging Het
Nemf A C 12: 69,344,986 probably benign Het
Osr1 A G 12: 9,579,370 D81G probably damaging Het
Prkce C T 17: 86,630,085 R649C probably damaging Het
Ptpn5 A G 7: 47,091,555 V14A probably benign Het
Rnf166 C A 8: 122,470,342 C57F probably damaging Het
Tenm3 A G 8: 48,276,645 I1426T probably benign Het
Trpm6 C T 19: 18,796,530 Q424* probably null Het
Ttc27 T A 17: 74,835,357 S606T probably damaging Het
Tyrp1 T C 4: 80,840,765 S292P possibly damaging Het
Wdr70 A G 15: 8,079,263 V133A probably benign Het
Wdr78 G A 4: 103,072,687 P369L possibly damaging Het
Ylpm1 T C 12: 85,015,455 F252S possibly damaging Het
Other mutations in Pate4
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0096:Pate4 UTSW 9 35611834 missense probably damaging 1.00
R2091:Pate4 UTSW 9 35608257 missense possibly damaging 0.84
R3912:Pate4 UTSW 9 35611844 start codon destroyed probably null 0.82
R3913:Pate4 UTSW 9 35611844 start codon destroyed probably null 0.82
R4864:Pate4 UTSW 9 35608239 missense probably damaging 1.00
R5443:Pate4 UTSW 9 35607874 missense possibly damaging 0.74
R6182:Pate4 UTSW 9 35608290 missense possibly damaging 0.79
R6273:Pate4 UTSW 9 35607790 missense probably benign 0.02
Posted On2013-12-03