Incidental Mutation 'IGL01531:Svopl'
ID89777
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Svopl
Ensembl Gene ENSMUSG00000029830
Gene NameSV2 related protein homolog (rat)-like
Synonyms9430071P14Rik
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01531
Quality Score
Status
Chromosome6
Chromosomal Location37983739-38046996 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to C at 38026941 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s): [ENSMUST00000096040]
Predicted Effect noncoding transcript
Transcript: ENSMUST00000040486
Predicted Effect probably benign
Transcript: ENSMUST00000096040
SMART Domains Protein: ENSMUSP00000093743
Gene: ENSMUSG00000029830

DomainStartEndE-ValueType
Pfam:Sugar_tr 17 297 5.5e-20 PFAM
Pfam:MFS_1 50 308 2.1e-20 PFAM
transmembrane domain 349 371 N/A INTRINSIC
transmembrane domain 384 406 N/A INTRINSIC
transmembrane domain 459 481 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000172585
Predicted Effect noncoding transcript
Transcript: ENSMUST00000173428
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is thought to be a member of solute carrier family 22, which includes transmembrane proteins that transport toxins and drugs from the body. This gene is a paralog of the SVOP gene that encodes synaptic vesicle 2-related protein. [provided by RefSeq, Sep 2016]
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4833420G17Rik T A 13: 119,466,958 probably null Het
Adcy1 T C 11: 7,169,414 V1019A possibly damaging Het
Blm A G 7: 80,474,071 Y1004H probably damaging Het
Btbd11 T C 10: 85,629,205 probably benign Het
Cachd1 A C 4: 100,953,034 I278L probably benign Het
Ddx18 T A 1: 121,564,586 T131S probably benign Het
Dgkd T C 1: 87,880,411 F67S probably damaging Het
Dlgap1 A G 17: 70,516,379 T120A probably damaging Het
Dnaja3 T G 16: 4,694,404 V224G probably damaging Het
Dntt A T 19: 41,053,238 R454* probably null Het
Dync2h1 T A 9: 7,071,111 T3083S probably benign Het
Eea1 C A 10: 96,031,677 T1045K probably damaging Het
Gpnmb T A 6: 49,047,458 probably benign Het
Hirip3 A G 7: 126,863,376 E108G possibly damaging Het
Il33 C A 19: 29,951,981 Q35K possibly damaging Het
Il6ra G A 3: 89,886,043 L267F probably damaging Het
Impact C T 18: 12,976,019 S69F probably benign Het
Klk9 G A 7: 43,792,251 G39D probably damaging Het
Ldah A G 12: 8,227,337 D91G probably benign Het
Lrp4 T C 2: 91,511,553 L1837P probably damaging Het
Mov10l1 T A 15: 89,054,352 H1204Q probably damaging Het
Nlrp4c A G 7: 6,060,656 E21G probably damaging Het
Olfr361 T C 2: 37,085,395 M118V possibly damaging Het
Olfr629 T A 7: 103,741,114 N42I probably damaging Het
Osbpl1a T G 18: 12,933,581 K40N probably damaging Het
Ptprd T C 4: 76,085,520 T1010A probably damaging Het
Rp1 A G 1: 4,348,945 V648A probably benign Het
Scn9a T C 2: 66,537,378 K654E probably benign Het
Sema3d A G 5: 12,541,080 I309V probably benign Het
Slc6a2 T C 8: 92,995,682 L519P probably damaging Het
Stard9 A G 2: 120,673,604 I211V possibly damaging Het
Stau2 T C 1: 16,345,698 *480W probably null Het
Virma A G 4: 11,528,753 E1330G probably damaging Het
Zan G A 5: 137,424,612 T2713I unknown Het
Other mutations in Svopl
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00742:Svopl APN 6 38031017 critical splice donor site probably null
IGL02161:Svopl APN 6 38036815 splice site probably benign
IGL02554:Svopl APN 6 38017043 missense probably damaging 0.99
IGL03249:Svopl APN 6 38017053 missense probably benign 0.05
PIT4434001:Svopl UTSW 6 38014866 missense possibly damaging 0.85
R0285:Svopl UTSW 6 37984522 missense probably benign 0.02
R0423:Svopl UTSW 6 38036707 splice site probably benign
R0692:Svopl UTSW 6 38017196 missense probably damaging 1.00
R0960:Svopl UTSW 6 38017057 nonsense probably null
R1163:Svopl UTSW 6 38029700 missense possibly damaging 0.89
R1526:Svopl UTSW 6 38029635 missense probably benign 0.03
R2295:Svopl UTSW 6 38019733 missense possibly damaging 0.52
R2302:Svopl UTSW 6 38041166 splice site probably benign
R5933:Svopl UTSW 6 38017014 splice site probably benign
R6367:Svopl UTSW 6 38019679 missense possibly damaging 0.88
R6595:Svopl UTSW 6 38041067 splice site probably null
R6903:Svopl UTSW 6 38021608 missense probably benign 0.00
Posted On2013-12-03