Incidental Mutation 'IGL01533:Tex264'
ID89842
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tex264
Ensembl Gene ENSMUSG00000040813
Gene Nametestis expressed gene 264
SynonymsTEG-264
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.191) question?
Stock #IGL01533
Quality Score
Status
Chromosome9
Chromosomal Location106658746-106685927 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 106673599 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Threonine at position 133 (I133T)
Ref Sequence ENSEMBL: ENSMUSP00000133194 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000046735] [ENSMUST00000163441] [ENSMUST00000169068]
Predicted Effect probably benign
Transcript: ENSMUST00000046735
AA Change: I133T

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000044654
Gene: ENSMUSG00000040813
AA Change: I133T

DomainStartEndE-ValueType
transmembrane domain 5 27 N/A INTRINSIC
Pfam:GyrI-like 41 185 1e-12 PFAM
low complexity region 208 225 N/A INTRINSIC
low complexity region 258 291 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000163441
AA Change: I133T

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000132247
Gene: ENSMUSG00000040813
AA Change: I133T

DomainStartEndE-ValueType
transmembrane domain 5 27 N/A INTRINSIC
SCOP:d1jyha_ 46 133 7e-3 SMART
low complexity region 208 225 N/A INTRINSIC
low complexity region 258 291 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000169068
AA Change: I133T

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000133194
Gene: ENSMUSG00000040813
AA Change: I133T

DomainStartEndE-ValueType
transmembrane domain 5 27 N/A INTRINSIC
Pfam:GyrI-like 41 176 4.2e-11 PFAM
low complexity region 220 253 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000185257
Predicted Effect noncoding transcript
Transcript: ENSMUST00000188120
Predicted Effect noncoding transcript
Transcript: ENSMUST00000188892
Predicted Effect noncoding transcript
Transcript: ENSMUST00000190948
Predicted Effect noncoding transcript
Transcript: ENSMUST00000214885
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 41 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Afg3l2 C A 18: 67,405,418 E757* probably null Het
Arhgap15 T C 2: 44,243,153 V357A probably damaging Het
Asb13 T C 13: 3,642,164 V48A probably benign Het
Bbs7 T C 3: 36,610,235 R74G possibly damaging Het
Capn11 T C 17: 45,632,904 H568R probably benign Het
Cbx5 T C 15: 103,205,634 E61G probably damaging Het
Ccdc158 T C 5: 92,609,956 probably null Het
Col14a1 C A 15: 55,420,840 N832K unknown Het
Cyp2a4 A T 7: 26,308,544 K125N probably damaging Het
Dhx16 T C 17: 35,882,047 L215P probably damaging Het
Dtx4 T C 19: 12,478,215 M480V possibly damaging Het
Edaradd A G 13: 12,478,582 probably benign Het
Galnt13 T A 2: 54,880,132 M312K probably damaging Het
Gcdh T A 8: 84,889,362 R337W probably damaging Het
Gm28557 A T 13: 67,071,332 C109* probably null Het
Gpr22 C T 12: 31,708,710 probably benign Het
Gria4 T G 9: 4,502,395 L379F probably damaging Het
Gxylt2 T C 6: 100,783,137 L211P probably damaging Het
Igsf10 T A 3: 59,319,230 I2341F probably damaging Het
Macf1 T C 4: 123,473,873 D2365G probably damaging Het
Morc2b A G 17: 33,135,721 probably benign Het
Ncoa3 T C 2: 166,055,025 S579P probably benign Het
Nlgn1 T C 3: 25,436,363 N400S possibly damaging Het
Olfr1141 C A 2: 87,753,068 R308S probably benign Het
Olfr146 C T 9: 39,018,801 A247T probably damaging Het
Pi4ka A G 16: 17,308,201 S1102P probably benign Het
Polr1e A G 4: 45,019,328 Y59C probably damaging Het
Prex2 C T 1: 11,186,741 Q1226* probably null Het
Rab12 A T 17: 66,497,435 I176K probably damaging Het
Ryr2 A T 13: 11,721,790 N2250K probably damaging Het
Sbf1 T C 15: 89,288,716 T1865A probably damaging Het
Sema6b G A 17: 56,129,499 probably benign Het
Smarcb1 C T 10: 75,916,768 probably null Het
Sos1 A G 17: 80,415,082 L845S probably damaging Het
Stat4 T A 1: 52,098,419 N456K probably damaging Het
Thoc1 T C 18: 9,962,376 V87A probably benign Het
Tmem131 C T 1: 36,818,722 D778N probably damaging Het
Tspan14 A G 14: 40,916,819 I88T probably benign Het
Ttn A G 2: 76,951,941 S984P probably damaging Het
Ttn C A 2: 76,732,574 V28679L possibly damaging Het
Vangl1 T C 3: 102,163,351 E423G possibly damaging Het
Other mutations in Tex264
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01308:Tex264 APN 9 106662408 missense possibly damaging 0.95
R0712:Tex264 UTSW 9 106659232 missense possibly damaging 0.88
R0737:Tex264 UTSW 9 106659299 missense probably benign 0.42
R1579:Tex264 UTSW 9 106681917 missense possibly damaging 0.95
R2983:Tex264 UTSW 9 106682097 missense unknown
R4772:Tex264 UTSW 9 106673702 missense possibly damaging 0.92
Posted On2013-12-03