Incidental Mutation 'IGL01539:Vmn1r222'
| ID |
90091 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r222
|
| Ensembl Gene |
ENSMUSG00000061022 |
| Gene Name |
vomeronasal 1 receptor 222 |
| Synonyms |
V1rh16 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.099)
|
| Stock # |
IGL01539
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
13 |
| Chromosomal Location |
23416285-23417211 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 23417059 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 51
(F51L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000076365
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000077116]
|
| AlphaFold |
Q8R269 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000077116
AA Change: F51L
PolyPhen 2
Score 0.446 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000076365
Gene: ENSMUSG00000061022
AA Change: F51L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:V1R
|
32 |
297 |
3.6e-39 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000225143
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 27 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Clca4b |
T |
A |
3: 144,631,918 (GRCm39) |
M196L |
probably benign |
Het |
| Cyp4a14 |
T |
C |
4: 115,344,374 (GRCm39) |
N497S |
possibly damaging |
Het |
| Eif3b |
T |
C |
5: 140,416,008 (GRCm39) |
|
probably benign |
Het |
| Grin2c |
T |
C |
11: 115,140,932 (GRCm39) |
Q1062R |
probably benign |
Het |
| Ina |
A |
G |
19: 47,003,903 (GRCm39) |
E237G |
probably damaging |
Het |
| Lmx1b |
T |
C |
2: 33,529,510 (GRCm39) |
D83G |
possibly damaging |
Het |
| Macf1 |
A |
G |
4: 123,289,701 (GRCm39) |
|
probably benign |
Het |
| Muc6 |
T |
A |
7: 141,236,306 (GRCm39) |
M406L |
probably benign |
Het |
| Myo15b |
T |
C |
11: 115,754,299 (GRCm39) |
I933T |
probably benign |
Het |
| Or4c121 |
A |
G |
2: 89,023,836 (GRCm39) |
F181L |
possibly damaging |
Het |
| Or6c204 |
T |
C |
10: 129,022,804 (GRCm39) |
N162S |
probably benign |
Het |
| Pde1b |
A |
T |
15: 103,433,772 (GRCm39) |
|
probably benign |
Het |
| Rab29 |
G |
A |
1: 131,798,445 (GRCm39) |
R75Q |
probably damaging |
Het |
| Scn10a |
A |
T |
9: 119,467,764 (GRCm39) |
I792N |
probably damaging |
Het |
| Serpinb6a |
A |
T |
13: 34,114,117 (GRCm39) |
V70D |
probably damaging |
Het |
| Slco1a7 |
A |
G |
6: 141,673,333 (GRCm39) |
S402P |
possibly damaging |
Het |
| Spart |
A |
G |
3: 55,024,723 (GRCm39) |
D106G |
possibly damaging |
Het |
| Sucla2 |
A |
G |
14: 73,828,561 (GRCm39) |
E359G |
probably damaging |
Het |
| Sycp2 |
T |
C |
2: 178,016,488 (GRCm39) |
Y658C |
probably damaging |
Het |
| Tenm2 |
T |
A |
11: 35,997,654 (GRCm39) |
T811S |
possibly damaging |
Het |
| Trim66 |
C |
A |
7: 109,054,273 (GRCm39) |
M1312I |
probably benign |
Het |
| Tspan18 |
A |
G |
2: 93,041,198 (GRCm39) |
S135P |
probably damaging |
Het |
| Ube2j1 |
T |
C |
4: 33,043,993 (GRCm39) |
|
probably benign |
Het |
| Ubr1 |
A |
C |
2: 120,756,494 (GRCm39) |
V711G |
possibly damaging |
Het |
| Veph1 |
T |
C |
3: 66,065,496 (GRCm39) |
T524A |
probably benign |
Het |
| Vwf |
G |
T |
6: 125,567,225 (GRCm39) |
V338L |
possibly damaging |
Het |
| Zfp770 |
G |
T |
2: 114,027,574 (GRCm39) |
A165E |
probably damaging |
Het |
|
| Other mutations in Vmn1r222 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01960:Vmn1r222
|
APN |
13 |
23,416,315 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02082:Vmn1r222
|
APN |
13 |
23,416,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02616:Vmn1r222
|
APN |
13 |
23,416,311 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL03155:Vmn1r222
|
APN |
13 |
23,416,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03333:Vmn1r222
|
APN |
13 |
23,417,177 (GRCm39) |
missense |
probably benign |
0.18 |
|
IGL03391:Vmn1r222
|
APN |
13 |
23,416,632 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0137:Vmn1r222
|
UTSW |
13 |
23,416,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1584:Vmn1r222
|
UTSW |
13 |
23,416,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2352:Vmn1r222
|
UTSW |
13 |
23,416,683 (GRCm39) |
missense |
probably benign |
0.35 |
|
R3079:Vmn1r222
|
UTSW |
13 |
23,416,631 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R3080:Vmn1r222
|
UTSW |
13 |
23,416,631 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R3963:Vmn1r222
|
UTSW |
13 |
23,417,102 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4448:Vmn1r222
|
UTSW |
13 |
23,416,830 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4448:Vmn1r222
|
UTSW |
13 |
23,416,463 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4979:Vmn1r222
|
UTSW |
13 |
23,416,602 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R5054:Vmn1r222
|
UTSW |
13 |
23,416,901 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5182:Vmn1r222
|
UTSW |
13 |
23,416,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5230:Vmn1r222
|
UTSW |
13 |
23,417,172 (GRCm39) |
missense |
probably benign |
|
|
R5462:Vmn1r222
|
UTSW |
13 |
23,417,045 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5611:Vmn1r222
|
UTSW |
13 |
23,416,743 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5677:Vmn1r222
|
UTSW |
13 |
23,416,950 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6298:Vmn1r222
|
UTSW |
13 |
23,416,965 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6655:Vmn1r222
|
UTSW |
13 |
23,416,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6748:Vmn1r222
|
UTSW |
13 |
23,417,117 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6912:Vmn1r222
|
UTSW |
13 |
23,416,374 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7663:Vmn1r222
|
UTSW |
13 |
23,416,601 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7764:Vmn1r222
|
UTSW |
13 |
23,416,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8675:Vmn1r222
|
UTSW |
13 |
23,416,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8774:Vmn1r222
|
UTSW |
13 |
23,416,418 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8774-TAIL:Vmn1r222
|
UTSW |
13 |
23,416,418 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9320:Vmn1r222
|
UTSW |
13 |
23,416,418 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1177:Vmn1r222
|
UTSW |
13 |
23,416,630 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
| Posted On |
2013-12-03 |
Incidental Mutation