Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01550:Vmn2r124'

90587

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r124

Ensembl Gene

ENSMUSG00000094396

Gene Name

vomeronasal 2, receptor 124

Synonyms

Vmn2r-ps113, Gm7196

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.270) question?

Stock #

IGL01550

Quality Score

Status

Chromosome

Chromosomal Location

18269746-18294482 bp(+) (GRCm39)

Type of Mutation

critical splice donor site (2 bp from exon)

DNA Base Change (assembly)

T to C at 18283617 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000135613 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000176802] [ENSMUST00000231546]

AlphaFold

K7N789

Predicted Effect

probably null
Transcript: ENSMUST00000176802

SMART Domains

Protein: ENSMUSP00000135613
Gene: ENSMUSG00000094396

Domain	Start	End	E-Value	Type
signal peptide	1	20	N/A	INTRINSIC
Pfam:ANF_receptor	84	449	2.2e-37	PFAM
Pfam:NCD3G	510	563	9.3e-21	PFAM
Pfam:7tm_3	596	831	1.6e-52	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000231546

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 28 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930556J24Rik	T	G	11: 3,887,974 (GRCm39)	R137S	unknown	Het
Epha8	G	T	4: 136,659,051 (GRCm39)	Q868K	possibly damaging	Het
Erc1	T	A	6: 119,760,355 (GRCm39)	M386L	probably damaging	Het
Gfpt2	T	A	11: 49,715,150 (GRCm39)		probably null	Het
Gpr142	T	A	11: 114,695,152 (GRCm39)	L39Q	probably damaging	Het
Hmcn1	A	T	1: 150,474,148 (GRCm39)	W4765R	probably damaging	Het
Hmcn2	A	T	2: 31,314,264 (GRCm39)	E3603V	possibly damaging	Het
Hsp90b1	C	T	10: 86,540,234 (GRCm39)	D26N	probably benign	Het
Kmt2c	T	C	5: 25,486,274 (GRCm39)	T4760A	probably damaging	Het
Lmo7	C	A	14: 102,163,576 (GRCm39)		probably benign	Het
Mup4	A	T	4: 59,960,120 (GRCm39)	I48K	probably damaging	Het
Mylk3	T	A	8: 86,091,718 (GRCm39)	D29V	probably damaging	Het
Myo1b	A	G	1: 51,823,690 (GRCm39)	F405S	probably damaging	Het
Nbea	T	C	3: 55,712,669 (GRCm39)	D2136G	possibly damaging	Het
Or1l4b	A	T	2: 37,036,986 (GRCm39)	Y254F	probably damaging	Het
Or52a20	T	G	7: 103,366,204 (GRCm39)	H134Q	probably damaging	Het
Or5g27	T	A	2: 85,409,875 (GRCm39)	C97*	probably null	Het
Or7e175	A	T	9: 20,048,750 (GRCm39)	T113S	probably damaging	Het
Psmg2	G	A	18: 67,786,293 (GRCm39)	V218I	probably benign	Het
Rpp40	T	C	13: 36,090,183 (GRCm39)		probably null	Het
Samd7	T	A	3: 30,819,399 (GRCm39)	S383T	probably damaging	Het
Tbc1d10c	T	C	19: 4,234,823 (GRCm39)	T413A	probably damaging	Het
Tlr12	A	G	4: 128,509,535 (GRCm39)	L905P	probably damaging	Het
Tnr	A	G	1: 159,701,828 (GRCm39)	K643R	probably benign	Het
Vwf	A	T	6: 125,656,252 (GRCm39)	I2606F	probably benign	Het
Wbp4	T	C	14: 79,703,774 (GRCm39)	T258A	probably benign	Het
Zfp1005	T	A	2: 150,108,363 (GRCm39)		probably benign	Het
Zfp758	T	C	17: 22,594,021 (GRCm39)	L137S	probably damaging	Het

Other mutations in Vmn2r124

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00988:Vmn2r124	APN	17	18,282,932 (GRCm39)	missense	probably benign	0.04
IGL01356:Vmn2r124	APN	17	18,293,733 (GRCm39)	missense	probably benign	0.08
IGL01387:Vmn2r124	APN	17	18,283,188 (GRCm39)	missense	probably damaging	0.98
IGL01413:Vmn2r124	APN	17	18,282,827 (GRCm39)	missense	probably benign	0.41
IGL01759:Vmn2r124	APN	17	18,284,330 (GRCm39)	missense	probably benign	0.00
IGL01762:Vmn2r124	APN	17	18,283,434 (GRCm39)	missense	possibly damaging	0.51
IGL02132:Vmn2r124	APN	17	18,284,491 (GRCm39)	splice site	probably benign
IGL02290:Vmn2r124	APN	17	18,293,597 (GRCm39)	missense	probably benign	0.09
IGL02370:Vmn2r124	APN	17	18,284,453 (GRCm39)	missense	probably benign	0.14
IGL02527:Vmn2r124	APN	17	18,286,764 (GRCm39)	critical splice acceptor site	probably null
PIT4280001:Vmn2r124	UTSW	17	18,283,487 (GRCm39)	missense	probably benign	0.22
PIT4514001:Vmn2r124	UTSW	17	18,293,974 (GRCm39)	missense	probably benign	0.01
R0362:Vmn2r124	UTSW	17	18,284,486 (GRCm39)	critical splice donor site	probably null
R0401:Vmn2r124	UTSW	17	18,284,407 (GRCm39)	missense	probably damaging	0.99
R0513:Vmn2r124	UTSW	17	18,293,991 (GRCm39)	missense	possibly damaging	0.89
R1139:Vmn2r124	UTSW	17	18,294,052 (GRCm39)	missense	possibly damaging	0.56
R1513:Vmn2r124	UTSW	17	18,283,535 (GRCm39)	missense	probably damaging	1.00
R1669:Vmn2r124	UTSW	17	18,283,206 (GRCm39)	missense	possibly damaging	0.94
R1710:Vmn2r124	UTSW	17	18,282,187 (GRCm39)	splice site	probably benign
R1852:Vmn2r124	UTSW	17	18,283,436 (GRCm39)	missense	probably benign
R1860:Vmn2r124	UTSW	17	18,269,759 (GRCm39)	missense	probably benign	0.11
R1953:Vmn2r124	UTSW	17	18,283,122 (GRCm39)	missense	probably benign	0.08
R2233:Vmn2r124	UTSW	17	18,269,927 (GRCm39)	missense	possibly damaging	0.95
R2234:Vmn2r124	UTSW	17	18,269,927 (GRCm39)	missense	possibly damaging	0.95
R2235:Vmn2r124	UTSW	17	18,269,927 (GRCm39)	missense	possibly damaging	0.95
R2397:Vmn2r124	UTSW	17	18,269,859 (GRCm39)	missense	possibly damaging	0.95
R2519:Vmn2r124	UTSW	17	18,294,280 (GRCm39)	missense	probably damaging	1.00
R3845:Vmn2r124	UTSW	17	18,293,953 (GRCm39)	missense	possibly damaging	0.90
R3846:Vmn2r124	UTSW	17	18,293,953 (GRCm39)	missense	possibly damaging	0.90
R4594:Vmn2r124	UTSW	17	18,294,231 (GRCm39)	missense	probably damaging	1.00
R4612:Vmn2r124	UTSW	17	18,283,284 (GRCm39)	missense	probably benign	0.12
R4790:Vmn2r124	UTSW	17	18,269,855 (GRCm39)	missense	probably damaging	1.00
R4809:Vmn2r124	UTSW	17	18,294,007 (GRCm39)	missense	probably benign	0.00
R5227:Vmn2r124	UTSW	17	18,269,819 (GRCm39)	missense	possibly damaging	0.95
R5254:Vmn2r124	UTSW	17	18,283,339 (GRCm39)	missense	probably benign	0.00
R5609:Vmn2r124	UTSW	17	18,294,102 (GRCm39)	missense	probably benign
R6145:Vmn2r124	UTSW	17	18,283,113 (GRCm39)	missense	probably benign	0.05
R6181:Vmn2r124	UTSW	17	18,294,019 (GRCm39)	missense	possibly damaging	0.93
R6271:Vmn2r124	UTSW	17	18,283,145 (GRCm39)	missense	probably benign	0.01
R7297:Vmn2r124	UTSW	17	18,293,835 (GRCm39)	missense	probably damaging	1.00
R7397:Vmn2r124	UTSW	17	18,282,947 (GRCm39)	missense	probably damaging	1.00
R7406:Vmn2r124	UTSW	17	18,282,306 (GRCm39)	missense	unknown
R7699:Vmn2r124	UTSW	17	18,293,985 (GRCm39)	missense	probably benign	0.00
R7859:Vmn2r124	UTSW	17	18,282,212 (GRCm39)	missense	probably damaging	1.00
R8121:Vmn2r124	UTSW	17	18,282,433 (GRCm39)	missense	probably benign
R8138:Vmn2r124	UTSW	17	18,283,610 (GRCm39)	missense	probably damaging	0.99
R8756:Vmn2r124	UTSW	17	18,294,094 (GRCm39)	missense	probably benign	0.08
R8796:Vmn2r124	UTSW	17	18,282,933 (GRCm39)	missense	possibly damaging	0.95
R8841:Vmn2r124	UTSW	17	18,283,299 (GRCm39)	missense
R8960:Vmn2r124	UTSW	17	18,283,291 (GRCm39)	nonsense	probably null
R8970:Vmn2r124	UTSW	17	18,294,439 (GRCm39)	missense	probably benign
R9128:Vmn2r124	UTSW	17	18,294,439 (GRCm39)	missense	probably benign
R9566:Vmn2r124	UTSW	17	18,293,581 (GRCm39)	missense	probably benign	0.14
R9680:Vmn2r124	UTSW	17	18,293,758 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-12-09