Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01591:Vmn2r92'

91593

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r92

Ensembl Gene

ENSMUSG00000091350

Gene Name

vomeronasal 2, receptor 92

Synonyms

EG627111

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.101) question?

Stock #

IGL01591

Quality Score

Status

Chromosome

Chromosomal Location

18372192-18405440 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 18405423 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Valine at position 856 (I856V)

Ref Sequence

ENSEMBL: ENSMUSP00000128685 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000169686]

AlphaFold

L7N2A4

Predicted Effect

unknown
Transcript: ENSMUST00000169686
AA Change: I856V

SMART Domains

Protein: ENSMUSP00000128685
Gene: ENSMUSG00000091350
AA Change: I856V

Domain	Start	End	E-Value	Type
signal peptide	1	20	N/A	INTRINSIC
Pfam:ANF_receptor	83	463	4.7e-38	PFAM
Pfam:NCD3G	510	564	2.5e-19	PFAM
Pfam:7tm_3	597	832	1.1e-52	PFAM
low complexity region	843	855	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 24 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acaca	G	T	11: 84,134,146 (GRCm39)	G420W	probably damaging	Het
Adamts17	G	A	7: 66,654,144 (GRCm39)	R458H	probably damaging	Het
Adprs	T	C	4: 126,212,274 (GRCm39)	T82A	probably damaging	Het
Ccdc158	T	A	5: 92,809,900 (GRCm39)	I203L	probably benign	Het
Commd10	C	A	18: 47,096,735 (GRCm39)	S47R	probably benign	Het
Crb1	T	C	1: 139,165,077 (GRCm39)	T1016A	probably damaging	Het
Crhbp	T	A	13: 95,580,295 (GRCm39)	I95F	probably damaging	Het
Cyp3a11	A	T	5: 145,812,291 (GRCm39)		probably benign	Het
Dsel	A	G	1: 111,787,425 (GRCm39)	Y1037H	probably benign	Het
Epha1	T	C	6: 42,337,485 (GRCm39)	D898G	probably damaging	Het
Esr2	T	A	12: 76,168,498 (GRCm39)		probably benign	Het
Exosc10	T	A	4: 148,647,344 (GRCm39)		probably benign	Het
Fat4	A	T	3: 39,064,524 (GRCm39)	R4827*	probably null	Het
Gm11596	A	T	11: 99,683,624 (GRCm39)	C165*	probably null	Het
Heatr5b	A	G	17: 79,115,901 (GRCm39)	S852P	probably benign	Het
Mcm3ap	C	T	10: 76,306,639 (GRCm39)	P251S	probably benign	Het
Nmur2	A	G	11: 55,917,825 (GRCm39)	V388A	probably benign	Het
Parp14	T	C	16: 35,678,877 (GRCm39)	T364A	possibly damaging	Het
Rarb	T	A	14: 16,434,207 (GRCm38)	I370F	possibly damaging	Het
Rnf32	T	A	5: 29,429,272 (GRCm39)	I283N	probably damaging	Het
Smg8	A	G	11: 86,975,979 (GRCm39)	V77A	probably damaging	Het
Tnn	T	C	1: 159,953,144 (GRCm39)	E632G	probably damaging	Het
Trip11	A	T	12: 101,849,604 (GRCm39)	S1487T	probably damaging	Het
Vmn2r58	T	C	7: 41,514,753 (GRCm39)	K72R	probably benign	Het

Other mutations in Vmn2r92

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01758:Vmn2r92	APN	17	18,372,275 (GRCm39)	nonsense	probably null
IGL02614:Vmn2r92	APN	17	18,387,503 (GRCm39)	splice site	probably benign
IGL03095:Vmn2r92	APN	17	18,386,972 (GRCm39)	missense	possibly damaging	0.55
IGL03403:Vmn2r92	APN	17	18,387,114 (GRCm39)	missense	probably damaging	0.98
R0133:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R0225:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R0227:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R0265:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R0266:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R0267:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R0420:Vmn2r92	UTSW	17	18,389,183 (GRCm39)	missense	probably benign	0.01
R0426:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R0494:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R1253:Vmn2r92	UTSW	17	18,387,028 (GRCm39)	missense	probably benign	0.08
R1497:Vmn2r92	UTSW	17	18,387,625 (GRCm39)	missense	probably benign	0.02
R1571:Vmn2r92	UTSW	17	18,372,352 (GRCm39)	missense	probably damaging	0.96
R1656:Vmn2r92	UTSW	17	18,372,198 (GRCm39)	missense	probably benign
R1816:Vmn2r92	UTSW	17	18,386,939 (GRCm39)	missense	probably damaging	0.98
R2229:Vmn2r92	UTSW	17	18,387,654 (GRCm39)	missense	probably benign	0.01
R2909:Vmn2r92	UTSW	17	18,405,377 (GRCm39)	missense	possibly damaging	0.89
R3694:Vmn2r92	UTSW	17	18,372,205 (GRCm39)	nonsense	probably null
R4207:Vmn2r92	UTSW	17	18,404,523 (GRCm39)	missense	possibly damaging	0.62
R4548:Vmn2r92	UTSW	17	18,391,578 (GRCm39)	missense	probably benign
R4612:Vmn2r92	UTSW	17	18,387,132 (GRCm39)	missense	probably benign	0.25
R4742:Vmn2r92	UTSW	17	18,387,119 (GRCm39)	missense	probably benign	0.06
R4824:Vmn2r92	UTSW	17	18,372,183 (GRCm39)	utr 5 prime	probably benign
R4865:Vmn2r92	UTSW	17	18,387,634 (GRCm39)	missense	probably benign	0.16
R4900:Vmn2r92	UTSW	17	18,404,605 (GRCm39)	missense	probably benign	0.27
R5084:Vmn2r92	UTSW	17	18,405,439 (GRCm39)	makesense	probably null
R5140:Vmn2r92	UTSW	17	18,372,312 (GRCm39)	missense	probably benign	0.07
R5995:Vmn2r92	UTSW	17	18,389,213 (GRCm39)	critical splice donor site	probably null
R6045:Vmn2r92	UTSW	17	18,388,305 (GRCm39)	critical splice donor site	probably null
R6269:Vmn2r92	UTSW	17	18,387,036 (GRCm39)	missense	probably benign	0.01
R6877:Vmn2r92	UTSW	17	18,389,084 (GRCm39)	missense	probably damaging	1.00
R7151:Vmn2r92	UTSW	17	18,387,005 (GRCm39)	missense	probably benign	0.01
R7260:Vmn2r92	UTSW	17	18,387,138 (GRCm39)	missense	probably damaging	1.00
R7344:Vmn2r92	UTSW	17	18,387,513 (GRCm39)	missense	probably benign	0.01
R7514:Vmn2r92	UTSW	17	18,391,533 (GRCm39)	missense	probably damaging	1.00
R7576:Vmn2r92	UTSW	17	18,387,621 (GRCm39)	missense	probably benign	0.01
R7584:Vmn2r92	UTSW	17	18,387,028 (GRCm39)	missense	probably benign	0.08
R7912:Vmn2r92	UTSW	17	18,404,970 (GRCm39)	missense	possibly damaging	0.91
R7941:Vmn2r92	UTSW	17	18,405,099 (GRCm39)	missense	possibly damaging	0.89
R8178:Vmn2r92	UTSW	17	18,386,988 (GRCm39)	missense	possibly damaging	0.69
R8238:Vmn2r92	UTSW	17	18,405,278 (GRCm39)	missense	probably benign	0.00
R8239:Vmn2r92	UTSW	17	18,405,278 (GRCm39)	missense	probably benign	0.00
R8252:Vmn2r92	UTSW	17	18,387,134 (GRCm39)	missense	probably damaging	1.00
R8322:Vmn2r92	UTSW	17	18,386,886 (GRCm39)	missense	probably damaging	0.99
R8355:Vmn2r92	UTSW	17	18,405,061 (GRCm39)	missense	probably damaging	0.99
R9399:Vmn2r92	UTSW	17	18,389,137 (GRCm39)	missense	probably benign	0.29
R9639:Vmn2r92	UTSW	17	18,372,352 (GRCm39)	missense	probably damaging	0.96
R9747:Vmn2r92	UTSW	17	18,405,201 (GRCm39)	missense	possibly damaging	0.66
R9773:Vmn2r92	UTSW	17	18,386,949 (GRCm39)	missense	probably damaging	1.00
X0066:Vmn2r92	UTSW	17	18,405,157 (GRCm39)	missense	probably damaging	1.00
Z1177:Vmn2r92	UTSW	17	18,404,795 (GRCm39)	missense	probably damaging	0.96

Posted On

2013-12-09