Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01625:Sptan1'

92726

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Sptan1

Ensembl Gene

ENSMUSG00000057738

Gene Name

spectrin alpha, non-erythrocytic 1

Synonyms

alpha-fodrin, alphaII-spectrin, Spna2, 2610027H02Rik, Spna-2

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

IGL01625

Quality Score

Status

Chromosome

Chromosomal Location

29855572-29921463 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 29916126 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Alanine to Valine at position 2038 (A2038V)

Ref Sequence

ENSEMBL: ENSMUSP00000109348 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000046257] [ENSMUST00000095083] [ENSMUST00000100225] [ENSMUST00000113717] [ENSMUST00000113719] [ENSMUST00000129241]

AlphaFold

P16546

Predicted Effect

possibly damaging
Transcript: ENSMUST00000046257
AA Change: A2033V

PolyPhen 2 Score 0.827 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000047792
Gene: ENSMUSG00000057738
AA Change: A2033V

Domain	Start	End	E-Value	Type
SPEC	47	146	2.1e-30	SMART
SPEC	152	252	2.6e-35	SMART
SPEC	258	358	4.93e-36	SMART
SPEC	364	464	1.08e-27	SMART
SPEC	470	570	9.01e-30	SMART
SPEC	576	675	3.52e-32	SMART
SPEC	681	781	2.15e-36	SMART
SPEC	787	887	2.45e-40	SMART
SPEC	893	1068	1.18e-24	SMART
SH3	970	1025	8.24e-18	SMART
SPEC	1074	1210	6.52e-27	SMART
SPEC	1216	1316	1.44e-37	SMART
SPEC	1322	1422	4.43e-29	SMART
SPEC	1428	1528	7.54e-32	SMART
SPEC	1534	1635	9.65e-30	SMART
SPEC	1641	1741	2.32e-32	SMART
SPEC	1747	1847	6.98e-36	SMART
SPEC	1853	1953	1.53e-32	SMART
SPEC	1959	2060	6.23e-24	SMART
SPEC	2074	2174	2.08e-11	SMART
SPEC	2188	2289	1.07e-4	SMART
EFh	2307	2335	5.78e-7	SMART
EFh	2350	2378	3.85e-3	SMART
efhand_Ca_insen	2382	2451	6.74e-32	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000095083
AA Change: A2053V

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000092697
Gene: ENSMUSG00000057738
AA Change: A2053V

Domain	Start	End	E-Value	Type
SPEC	47	146	2.1e-30	SMART
SPEC	152	252	2.6e-35	SMART
SPEC	258	358	4.93e-36	SMART
SPEC	364	464	1.08e-27	SMART
SPEC	470	570	9.01e-30	SMART
SPEC	576	675	3.52e-32	SMART
SPEC	681	781	2.15e-36	SMART
SPEC	787	887	2.45e-40	SMART
SPEC	893	1088	1.56e-24	SMART
SH3	970	1025	8.24e-18	SMART
SPEC	1094	1230	6.52e-27	SMART
SPEC	1236	1336	1.44e-37	SMART
SPEC	1342	1442	4.43e-29	SMART
SPEC	1448	1548	7.54e-32	SMART
SPEC	1554	1655	9.65e-30	SMART
SPEC	1661	1761	2.32e-32	SMART
SPEC	1767	1867	6.98e-36	SMART
SPEC	1873	1973	1.53e-32	SMART
SPEC	1979	2080	6.23e-24	SMART
SPEC	2094	2194	2.08e-11	SMART
SPEC	2208	2309	1.07e-4	SMART
EFh	2327	2355	5.78e-7	SMART
EFh	2370	2398	3.85e-3	SMART
efhand_Ca_insen	2402	2471	6.74e-32	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000100225
AA Change: A2058V

PolyPhen 2 Score 0.985 (Sensitivity: 0.74; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000097797
Gene: ENSMUSG00000057738
AA Change: A2058V

Domain	Start	End	E-Value	Type
SPEC	47	146	2.1e-30	SMART
SPEC	152	252	2.6e-35	SMART
SPEC	258	358	4.93e-36	SMART
SPEC	364	464	1.08e-27	SMART
SPEC	470	570	9.01e-30	SMART
SPEC	576	675	3.52e-32	SMART
SPEC	681	781	2.15e-36	SMART
SPEC	787	887	2.45e-40	SMART
SPEC	893	1088	1.56e-24	SMART
SH3	970	1025	8.24e-18	SMART
SPEC	1094	1230	6.52e-27	SMART
SPEC	1236	1336	1.44e-37	SMART
SPEC	1342	1442	4.43e-29	SMART
SPEC	1448	1548	7.54e-32	SMART
SPEC	1554	1660	2.06e-24	SMART
SPEC	1666	1766	2.32e-32	SMART
SPEC	1772	1872	6.98e-36	SMART
SPEC	1878	1978	1.53e-32	SMART
SPEC	1984	2085	6.23e-24	SMART
SPEC	2099	2199	2.08e-11	SMART
SPEC	2213	2314	1.07e-4	SMART
EFh	2332	2360	5.78e-7	SMART
EFh	2375	2403	3.85e-3	SMART
efhand_Ca_insen	2407	2476	6.74e-32	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000113717
AA Change: A2038V

PolyPhen 2 Score 0.985 (Sensitivity: 0.74; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000109346
Gene: ENSMUSG00000057738
AA Change: A2038V

Domain	Start	End	E-Value	Type
SPEC	47	146	2.1e-30	SMART
SPEC	152	252	2.6e-35	SMART
SPEC	258	358	4.93e-36	SMART
SPEC	364	464	1.08e-27	SMART
SPEC	470	570	9.01e-30	SMART
SPEC	576	675	3.52e-32	SMART
SPEC	681	781	2.15e-36	SMART
SPEC	787	887	2.45e-40	SMART
SPEC	893	1068	1.18e-24	SMART
SH3	970	1025	8.24e-18	SMART
SPEC	1074	1210	6.52e-27	SMART
SPEC	1216	1316	1.44e-37	SMART
SPEC	1322	1422	4.43e-29	SMART
SPEC	1428	1528	7.54e-32	SMART
SPEC	1534	1640	2.06e-24	SMART
SPEC	1646	1746	2.32e-32	SMART
SPEC	1752	1852	6.98e-36	SMART
SPEC	1858	1958	1.53e-32	SMART
SPEC	1964	2065	6.23e-24	SMART
SPEC	2079	2179	2.08e-11	SMART
SPEC	2193	2294	1.07e-4	SMART
EFh	2312	2340	5.78e-7	SMART
EFh	2355	2383	3.85e-3	SMART
efhand_Ca_insen	2387	2456	6.74e-32	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000113719
AA Change: A2038V

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000109348
Gene: ENSMUSG00000057738
AA Change: A2038V

Domain	Start	End	E-Value	Type
SPEC	47	146	2.1e-30	SMART
SPEC	152	252	2.6e-35	SMART
SPEC	258	358	4.93e-36	SMART
SPEC	364	464	1.08e-27	SMART
SPEC	470	570	9.01e-30	SMART
SPEC	576	675	3.52e-32	SMART
SPEC	681	781	2.15e-36	SMART
SPEC	787	887	2.45e-40	SMART
SPEC	893	1068	1.18e-24	SMART
SH3	970	1025	8.24e-18	SMART
SPEC	1074	1210	6.52e-27	SMART
SPEC	1216	1316	1.44e-37	SMART
SPEC	1322	1422	4.43e-29	SMART
SPEC	1428	1528	7.54e-32	SMART
SPEC	1534	1640	2.06e-24	SMART
SPEC	1646	1746	2.32e-32	SMART
SPEC	1752	1852	6.98e-36	SMART
SPEC	1858	1958	1.53e-32	SMART
SPEC	1964	2065	6.23e-24	SMART
SPEC	2079	2179	2.08e-11	SMART
SPEC	2193	2315	3.27e0	SMART
EFh	2333	2361	5.78e-7	SMART
EFh	2376	2404	3.85e-3	SMART
efhand_Ca_insen	2408	2477	6.74e-32	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000124494

Predicted Effect

unknown
Transcript: ENSMUST00000129241
AA Change: A2058V

SMART Domains

Protein: ENSMUSP00000121116
Gene: ENSMUSG00000057738
AA Change: A2058V

Domain	Start	End	E-Value	Type
Pfam:Spectrin	1	65	9.9e-10	PFAM
SPEC	78	178	2.08e-11	SMART
SPEC	192	314	3.27e0	SMART
EFh	332	360	5.78e-7	SMART
EFh	375	403	3.85e-3	SMART
efhand_Ca_insen	407	476	6.74e-32	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000149846

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000152453

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000201758

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]
PHENOTYPE: Homozygous deletion of the exons encoding the CCC region are normal. Mice homozygous for a gene trap allele exhibit embryonic lethality and abnormal nervous system, heart and craniofacial morphology. [provided by MGI curators]

Allele List at MGI

All alleles(76) : Targeted(1) Gene trapped(75)

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700018F24Rik	T	A	5: 144,979,957 (GRCm39)	H37Q	possibly damaging	Het
Akr1c19	T	A	13: 4,283,816 (GRCm39)	I16N	probably damaging	Het
Arpc1b	T	C	5: 145,058,555 (GRCm39)		probably null	Het
Bzw1	A	G	1: 58,440,599 (GRCm39)	T191A	probably benign	Het
Cacna1h	G	A	17: 25,604,686 (GRCm39)	T1209I	possibly damaging	Het
Cacna1h	T	C	17: 25,602,459 (GRCm39)	D1523G	probably damaging	Het
Cdc20b	T	C	13: 113,196,319 (GRCm39)	L148P	possibly damaging	Het
Cubn	A	G	2: 13,311,085 (GRCm39)	F3147L	possibly damaging	Het
Dagla	A	G	19: 10,228,566 (GRCm39)		probably benign	Het
Dnah9	T	C	11: 65,935,471 (GRCm39)	N1983D	probably damaging	Het
Fbxw10	G	A	11: 62,750,853 (GRCm39)	D479N	probably damaging	Het
Fer	A	T	17: 64,344,621 (GRCm39)	Q630L	probably damaging	Het
Gbp5	A	G	3: 142,208,789 (GRCm39)	N111D	probably damaging	Het
Gm8127	T	G	14: 43,148,520 (GRCm39)		probably benign	Het
Heatr1	T	A	13: 12,428,409 (GRCm39)	N814K	probably damaging	Het
Iba57	G	A	11: 59,049,775 (GRCm39)	R191W	probably damaging	Het
Itgae	C	A	11: 73,010,263 (GRCm39)	F584L	probably benign	Het
Kdm5b	A	G	1: 134,545,706 (GRCm39)	K956E	possibly damaging	Het
Muc4	C	T	16: 32,575,918 (GRCm39)		probably benign	Het
Mybpc2	T	C	7: 44,166,337 (GRCm39)	K218E	possibly damaging	Het
Pcdh10	T	C	3: 45,333,832 (GRCm39)	S49P	probably damaging	Het
Prss3b	A	C	6: 41,009,882 (GRCm39)	S151A	probably benign	Het
Rai14	T	C	15: 10,572,460 (GRCm39)	D889G	probably benign	Het
Rbpjl	A	G	2: 164,249,705 (GRCm39)	K102R	possibly damaging	Het
Retreg2	A	G	1: 75,121,359 (GRCm39)		probably benign	Het
Rfc4	A	T	16: 22,934,573 (GRCm39)	L149Q	probably damaging	Het
Rft1	T	A	14: 30,398,853 (GRCm39)	D274E	possibly damaging	Het
Rlf	A	T	4: 121,045,457 (GRCm39)	S143R	possibly damaging	Het
Rptn	T	A	3: 93,305,201 (GRCm39)	S845T	probably benign	Het
Slamf8	C	A	1: 172,410,049 (GRCm39)	D267Y	probably damaging	Het
Smoc2	C	T	17: 14,545,876 (GRCm39)	S55L	probably damaging	Het
Stx17	C	A	4: 48,181,526 (GRCm39)	P210T	probably damaging	Het
Tbc1d5	A	G	17: 51,224,601 (GRCm39)	Y317H	probably benign	Het
Tenm4	C	A	7: 96,534,565 (GRCm39)	T1737N	probably damaging	Het
Tesk2	T	C	4: 116,628,998 (GRCm39)	F116L	possibly damaging	Het
Tln2	T	C	9: 67,277,905 (GRCm39)	S370G	probably damaging	Het
Tm6sf2	G	T	8: 70,528,733 (GRCm39)	G162C	probably null	Het
Togaram2	A	C	17: 72,021,693 (GRCm39)	E718D	probably benign	Het
Ttn	A	C	2: 76,578,327 (GRCm39)	F15862V	probably damaging	Het
Uba6	T	A	5: 86,268,388 (GRCm39)	R916*	probably null	Het
Umodl1	A	G	17: 31,215,229 (GRCm39)	M1018V	probably benign	Het
Wdr26	G	A	1: 181,019,381 (GRCm39)	T332I	possibly damaging	Het
Xdh	A	T	17: 74,223,781 (GRCm39)		probably null	Het

Other mutations in Sptan1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00668:Sptan1	APN	2	29,883,968 (GRCm39)	critical splice donor site	probably null
IGL00932:Sptan1	APN	2	29,905,622 (GRCm39)	missense	probably damaging	1.00
IGL00945:Sptan1	APN	2	29,890,083 (GRCm39)	splice site	probably benign
IGL01070:Sptan1	APN	2	29,904,185 (GRCm39)	critical splice donor site	probably null
IGL01657:Sptan1	APN	2	29,908,491 (GRCm39)	missense	probably benign	0.12
IGL01795:Sptan1	APN	2	29,908,501 (GRCm39)	missense	probably benign	0.07
IGL01982:Sptan1	APN	2	29,909,980 (GRCm39)	missense	probably damaging	1.00
IGL02040:Sptan1	APN	2	29,903,725 (GRCm39)	missense	probably benign	0.43
IGL02158:Sptan1	APN	2	29,920,336 (GRCm39)	missense	probably damaging	0.97
IGL02370:Sptan1	APN	2	29,920,752 (GRCm39)	missense	probably damaging	0.99
IGL02507:Sptan1	APN	2	29,906,067 (GRCm39)	missense	probably damaging	1.00
IGL02552:Sptan1	APN	2	29,908,486 (GRCm39)	missense	probably damaging	0.99
IGL02690:Sptan1	APN	2	29,888,195 (GRCm39)	missense	possibly damaging	0.78
IGL02715:Sptan1	APN	2	29,868,588 (GRCm39)	missense	probably benign	0.03
IGL02725:Sptan1	APN	2	29,886,055 (GRCm39)	missense	probably damaging	0.99
IGL03033:Sptan1	APN	2	29,881,045 (GRCm39)	missense	probably damaging	1.00
IGL03304:Sptan1	APN	2	29,876,505 (GRCm39)	missense	probably damaging	1.00
IGL03405:Sptan1	APN	2	29,915,593 (GRCm39)	missense	probably damaging	0.99
R0058:Sptan1	UTSW	2	29,883,708 (GRCm39)	splice site	probably null
R0058:Sptan1	UTSW	2	29,883,708 (GRCm39)	splice site	probably null
R0066:Sptan1	UTSW	2	29,893,679 (GRCm39)	splice site	probably benign
R0066:Sptan1	UTSW	2	29,893,679 (GRCm39)	splice site	probably benign
R0071:Sptan1	UTSW	2	29,893,354 (GRCm39)	nonsense	probably null
R0071:Sptan1	UTSW	2	29,893,354 (GRCm39)	nonsense	probably null
R0094:Sptan1	UTSW	2	29,896,635 (GRCm39)	missense	probably benign	0.37
R0230:Sptan1	UTSW	2	29,900,704 (GRCm39)	splice site	probably benign
R0242:Sptan1	UTSW	2	29,908,413 (GRCm39)	missense	probably benign	0.00
R0242:Sptan1	UTSW	2	29,908,413 (GRCm39)	missense	probably benign	0.00
R0366:Sptan1	UTSW	2	29,882,764 (GRCm39)	splice site	probably null
R0368:Sptan1	UTSW	2	29,883,927 (GRCm39)	missense	probably benign	0.29
R0396:Sptan1	UTSW	2	29,881,045 (GRCm39)	missense	probably damaging	1.00
R0423:Sptan1	UTSW	2	29,918,684 (GRCm39)	missense	probably null
R0448:Sptan1	UTSW	2	29,916,822 (GRCm39)	missense	probably damaging	1.00
R0485:Sptan1	UTSW	2	29,903,860 (GRCm39)	splice site	probably benign
R0580:Sptan1	UTSW	2	29,897,587 (GRCm39)	missense	probably damaging	0.99
R0739:Sptan1	UTSW	2	29,903,530 (GRCm39)	missense	probably damaging	1.00
R0924:Sptan1	UTSW	2	29,906,040 (GRCm39)	missense	probably damaging	0.98
R0930:Sptan1	UTSW	2	29,906,040 (GRCm39)	missense	probably damaging	0.98
R0961:Sptan1	UTSW	2	29,870,075 (GRCm39)	splice site	probably null
R1352:Sptan1	UTSW	2	29,911,199 (GRCm39)	splice site	probably benign
R1456:Sptan1	UTSW	2	29,870,215 (GRCm39)	critical splice donor site	probably null
R1537:Sptan1	UTSW	2	29,916,034 (GRCm39)	missense	possibly damaging	0.95
R1542:Sptan1	UTSW	2	29,917,139 (GRCm39)	missense	probably damaging	1.00
R1612:Sptan1	UTSW	2	29,893,348 (GRCm39)	missense	probably damaging	1.00
R1623:Sptan1	UTSW	2	29,876,432 (GRCm39)	missense	probably damaging	0.96
R1834:Sptan1	UTSW	2	29,882,013 (GRCm39)	splice site	probably benign
R1879:Sptan1	UTSW	2	29,885,540 (GRCm39)	missense	probably damaging	1.00
R1893:Sptan1	UTSW	2	29,910,472 (GRCm39)	missense	probably damaging	0.98
R1914:Sptan1	UTSW	2	29,901,048 (GRCm39)	missense	probably benign	0.00
R1915:Sptan1	UTSW	2	29,901,048 (GRCm39)	missense	probably benign	0.00
R2022:Sptan1	UTSW	2	29,897,573 (GRCm39)	missense	probably damaging	0.96
R2050:Sptan1	UTSW	2	29,892,250 (GRCm39)	missense	probably benign
R2103:Sptan1	UTSW	2	29,920,483 (GRCm39)	missense	probably damaging	1.00
R2162:Sptan1	UTSW	2	29,908,588 (GRCm39)	splice site	probably benign
R2931:Sptan1	UTSW	2	29,908,500 (GRCm39)	missense	probably benign
R3726:Sptan1	UTSW	2	29,908,431 (GRCm39)	missense	possibly damaging	0.59
R4170:Sptan1	UTSW	2	29,920,037 (GRCm39)	missense	possibly damaging	0.93
R4235:Sptan1	UTSW	2	29,916,600 (GRCm39)	missense	probably damaging	1.00
R4378:Sptan1	UTSW	2	29,915,581 (GRCm39)	missense	probably damaging	1.00
R4424:Sptan1	UTSW	2	29,919,721 (GRCm39)	intron	probably benign
R4718:Sptan1	UTSW	2	29,921,074 (GRCm39)	missense	probably damaging	1.00
R4777:Sptan1	UTSW	2	29,886,447 (GRCm39)	missense	probably damaging	0.98
R4849:Sptan1	UTSW	2	29,901,054 (GRCm39)	missense	probably damaging	1.00
R5158:Sptan1	UTSW	2	29,868,455 (GRCm39)	missense	probably damaging	1.00
R5180:Sptan1	UTSW	2	29,883,736 (GRCm39)	intron	probably benign
R5181:Sptan1	UTSW	2	29,883,736 (GRCm39)	intron	probably benign
R5383:Sptan1	UTSW	2	29,901,340 (GRCm39)	missense	probably damaging	1.00
R5573:Sptan1	UTSW	2	29,876,504 (GRCm39)	nonsense	probably null
R5592:Sptan1	UTSW	2	29,876,731 (GRCm39)	intron	probably benign
R5639:Sptan1	UTSW	2	29,881,005 (GRCm39)	nonsense	probably null
R5801:Sptan1	UTSW	2	29,920,613 (GRCm39)	splice site	probably null
R5947:Sptan1	UTSW	2	29,884,379 (GRCm39)	critical splice donor site	probably null
R6056:Sptan1	UTSW	2	29,886,794 (GRCm39)	missense	probably benign	0.36
R6090:Sptan1	UTSW	2	29,883,899 (GRCm39)	missense	probably damaging	1.00
R6146:Sptan1	UTSW	2	29,894,535 (GRCm39)	missense	probably benign	0.01
R6254:Sptan1	UTSW	2	29,897,561 (GRCm39)	missense	possibly damaging	0.93
R6366:Sptan1	UTSW	2	29,910,467 (GRCm39)	missense	possibly damaging	0.47
R6378:Sptan1	UTSW	2	29,908,527 (GRCm39)	missense	probably damaging	1.00
R6521:Sptan1	UTSW	2	29,910,467 (GRCm39)	missense	possibly damaging	0.47
R6877:Sptan1	UTSW	2	29,920,985 (GRCm39)	missense	probably damaging	0.99
R7173:Sptan1	UTSW	2	29,873,221 (GRCm39)	missense	probably benign	0.02
R7248:Sptan1	UTSW	2	29,892,311 (GRCm39)	missense	probably benign	0.10
R7282:Sptan1	UTSW	2	29,876,941 (GRCm39)	missense	probably damaging	1.00
R7527:Sptan1	UTSW	2	29,870,209 (GRCm39)	missense	probably damaging	1.00
R7585:Sptan1	UTSW	2	29,890,068 (GRCm39)	missense	probably benign	0.06
R7779:Sptan1	UTSW	2	29,911,319 (GRCm39)	missense	probably damaging	1.00
R8051:Sptan1	UTSW	2	29,920,171 (GRCm39)	missense	probably damaging	1.00
R8055:Sptan1	UTSW	2	29,884,351 (GRCm39)	missense	probably benign	0.22
R8103:Sptan1	UTSW	2	29,910,055 (GRCm39)	missense	probably damaging	1.00
R8283:Sptan1	UTSW	2	29,870,212 (GRCm39)	missense	probably damaging	1.00
R8507:Sptan1	UTSW	2	29,916,596 (GRCm39)	missense	probably damaging	1.00
R8963:Sptan1	UTSW	2	29,873,744 (GRCm39)	missense	possibly damaging	0.92
R9126:Sptan1	UTSW	2	29,920,597 (GRCm39)	missense	probably damaging	0.99
R9206:Sptan1	UTSW	2	29,920,724 (GRCm39)	missense	possibly damaging	0.90
R9273:Sptan1	UTSW	2	29,880,977 (GRCm39)	missense	possibly damaging	0.88
X0028:Sptan1	UTSW	2	29,910,042 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-12-09