Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01631:Tsga13'

93443

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tsga13

Ensembl Gene

ENSMUSG00000039032

Gene Name

testis specific gene A13

Synonyms

1700023D02Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.147) question?

Stock #

IGL01631

Quality Score

Status

Chromosome

Chromosomal Location

30873916-30892508 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 30890501 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Glutamic Acid at position 8 (K8E)

Ref Sequence

ENSEMBL: ENSMUSP00000040894 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000048580]

AlphaFold

Q9DA17

Predicted Effect

possibly damaging
Transcript: ENSMUST00000048580
AA Change: K8E

PolyPhen 2 Score 0.470 (Sensitivity: 0.89; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000040894
Gene: ENSMUSG00000039032
AA Change: K8E

Domain	Start	End	E-Value	Type
Pfam:TSGA13	3	271	9.5e-125	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000139006

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Apip	C	A	2: 102,904,194 (GRCm39)		probably benign	Het
Arid4a	C	T	12: 71,069,036 (GRCm39)		probably benign	Het
Brwd1	C	A	16: 95,847,666 (GRCm39)	E98D	probably damaging	Het
Cactin	A	G	10: 81,159,058 (GRCm39)	E303G	probably benign	Het
Ccdc181	T	A	1: 164,107,713 (GRCm39)	I132K	possibly damaging	Het
Celsr3	A	G	9: 108,714,603 (GRCm39)	H1995R	probably benign	Het
Cog4	A	G	8: 111,608,472 (GRCm39)	E756G	probably damaging	Het
Ctsf	T	C	19: 4,908,106 (GRCm39)	L217P	probably damaging	Het
Dmp1	G	T	5: 104,360,734 (GRCm39)	R470L	probably benign	Het
Dnajc9	T	C	14: 20,438,176 (GRCm39)	D142G	probably benign	Het
Ednrb	T	A	14: 104,080,661 (GRCm39)	R84S	probably benign	Het
Gm1110	A	T	9: 26,809,212 (GRCm39)		probably null	Het
Has2	A	G	15: 56,545,072 (GRCm39)	S177P	possibly damaging	Het
Herc6	C	T	6: 57,581,092 (GRCm39)	S264F	probably benign	Het
Il1rl2	T	A	1: 40,395,974 (GRCm39)		probably null	Het
Ltbp2	A	G	12: 84,855,920 (GRCm39)		probably null	Het
Map4	A	G	9: 109,892,201 (GRCm39)		probably benign	Het
Marchf4	T	A	1: 72,491,690 (GRCm39)	K194*	probably null	Het
Megf10	A	G	18: 57,392,869 (GRCm39)	D422G	possibly damaging	Het
Mfsd2a	C	A	4: 122,843,100 (GRCm39)	A394S	probably benign	Het
Mmp27	T	C	9: 7,573,289 (GRCm39)		probably benign	Het
Mvd	A	G	8: 123,161,560 (GRCm39)	Y370H	possibly damaging	Het
Or4a81	T	C	2: 89,619,129 (GRCm39)	D189G	probably damaging	Het
Or8b55	T	A	9: 38,727,335 (GRCm39)	C179S	probably damaging	Het
Pramel31	A	G	4: 144,089,015 (GRCm39)	H111R	probably benign	Het
Ptk2	G	A	15: 73,088,220 (GRCm39)	H859Y	probably damaging	Het
Ptprq	T	A	10: 107,479,399 (GRCm39)	E1209D	probably benign	Het
Rhot1	C	T	11: 80,156,600 (GRCm39)	T636M	probably damaging	Het
Ripk2	C	A	4: 16,163,342 (GRCm39)	A19S	possibly damaging	Het
Rsbn1l	G	A	5: 21,101,569 (GRCm39)	S657L	probably damaging	Het
Rsbn1l	A	T	5: 21,101,570 (GRCm39)	S657T	probably damaging	Het
Sema6c	A	G	3: 95,077,714 (GRCm39)	T450A	probably benign	Het
Slc25a1	C	T	16: 17,743,930 (GRCm39)	C262Y	probably damaging	Het
Slfn3	T	C	11: 83,104,361 (GRCm39)	S288P	probably damaging	Het
Snrnp200	T	A	2: 127,080,744 (GRCm39)		probably benign	Het
Spata31e2	T	C	1: 26,724,495 (GRCm39)	I228M	probably damaging	Het
Ssu2	T	C	6: 112,351,843 (GRCm39)	Y294C	probably damaging	Het
Terb1	A	G	8: 105,199,496 (GRCm39)	S483P	probably damaging	Het
Zbbx	T	G	3: 74,985,984 (GRCm39)	D351A	probably damaging	Het
Zfp454	G	T	11: 50,774,562 (GRCm39)	A37D	probably benign	Het

Other mutations in Tsga13

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02487:Tsga13	APN	6	30,884,362 (GRCm39)	missense	probably damaging	1.00
IGL02602:Tsga13	APN	6	30,879,212 (GRCm39)	missense	possibly damaging	0.92
R3894:Tsga13	UTSW	6	30,889,198 (GRCm39)	missense	probably benign
R4335:Tsga13	UTSW	6	30,876,980 (GRCm39)	missense	probably damaging	0.97
R4582:Tsga13	UTSW	6	30,879,298 (GRCm39)	missense	probably benign	0.04
R5705:Tsga13	UTSW	6	30,876,951 (GRCm39)	missense	probably damaging	1.00
R6248:Tsga13	UTSW	6	30,874,139 (GRCm39)	missense	probably benign	0.01
R7470:Tsga13	UTSW	6	30,876,981 (GRCm39)	missense	possibly damaging	0.70

Posted On

2013-12-09