Incidental Mutation 'IGL00807:Ccr1l1'
| ID |
9474 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Ccr1l1
|
| Ensembl Gene |
ENSMUSG00000064039 |
| Gene Name |
C-C motif chemokine receptor 1 like 1 |
| Synonyms |
MIP-1 alphaRL1, Cmkbr1l1 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL00807
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
9 |
| Chromosomal Location |
123777280-123778445 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 123777506 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tryptophan to Arginine
at position 314
(W314R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071353
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071404]
|
| AlphaFold |
P51676 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000071404
AA Change: W314R
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000071353
Gene: ENSMUSG00000064039
AA Change: W314R
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:7tm_1
|
52 |
302 |
6.6e-42 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a targeted null mutation do not exhibit any significant abnormalities compared to controls. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 19 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
A |
T |
11: 9,328,285 (GRCm39) |
T3453S |
probably benign |
Het |
| Ahnak |
T |
A |
19: 8,985,886 (GRCm39) |
V2390E |
possibly damaging |
Het |
| Aldh8a1 |
A |
T |
10: 21,271,329 (GRCm39) |
I352F |
probably damaging |
Het |
| Ccnt2 |
T |
C |
1: 127,725,628 (GRCm39) |
|
probably benign |
Het |
| Cdc42bpa |
A |
G |
1: 179,969,018 (GRCm39) |
I1218V |
possibly damaging |
Het |
| Dlc1 |
G |
A |
8: 37,040,002 (GRCm39) |
T1386I |
probably benign |
Het |
| Frs2 |
A |
C |
10: 116,910,791 (GRCm39) |
|
probably benign |
Het |
| Gria1 |
T |
C |
11: 56,902,866 (GRCm39) |
Y3H |
probably benign |
Het |
| Iigp1c |
C |
T |
18: 60,378,483 (GRCm39) |
S6F |
probably damaging |
Het |
| Ints2 |
T |
C |
11: 86,123,961 (GRCm39) |
N609S |
probably damaging |
Het |
| Lyst |
T |
A |
13: 13,825,008 (GRCm39) |
M1541K |
possibly damaging |
Het |
| Mmachc |
A |
T |
4: 116,563,118 (GRCm39) |
V79E |
probably damaging |
Het |
| Nfe2l2 |
T |
C |
2: 75,509,757 (GRCm39) |
D21G |
probably damaging |
Het |
| Pde2a |
G |
A |
7: 101,153,619 (GRCm39) |
V436M |
probably damaging |
Het |
| Polr1has |
G |
T |
17: 37,275,813 (GRCm39) |
A132S |
probably damaging |
Het |
| Rhot1 |
C |
T |
11: 80,116,928 (GRCm39) |
H101Y |
probably benign |
Het |
| Sh2d4a |
T |
C |
8: 68,782,018 (GRCm39) |
|
probably null |
Het |
| Taar2 |
A |
G |
10: 23,816,573 (GRCm39) |
M38V |
probably benign |
Het |
| Tek |
A |
T |
4: 94,686,956 (GRCm39) |
N158I |
probably damaging |
Het |
|
| Other mutations in Ccr1l1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02161:Ccr1l1
|
APN |
9 |
123,778,000 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02293:Ccr1l1
|
APN |
9 |
123,777,973 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL03179:Ccr1l1
|
APN |
9 |
123,777,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03294:Ccr1l1
|
APN |
9 |
123,778,444 (GRCm39) |
start codon destroyed |
probably null |
0.56 |
|
R1672:Ccr1l1
|
UTSW |
9 |
123,777,544 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2165:Ccr1l1
|
UTSW |
9 |
123,777,691 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2170:Ccr1l1
|
UTSW |
9 |
123,778,172 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2886:Ccr1l1
|
UTSW |
9 |
123,777,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4834:Ccr1l1
|
UTSW |
9 |
123,777,742 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5598:Ccr1l1
|
UTSW |
9 |
123,778,030 (GRCm39) |
missense |
probably benign |
|
|
R6458:Ccr1l1
|
UTSW |
9 |
123,778,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8525:Ccr1l1
|
UTSW |
9 |
123,777,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
X0019:Ccr1l1
|
UTSW |
9 |
123,777,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Ccr1l1
|
UTSW |
9 |
123,777,887 (GRCm39) |
missense |
probably benign |
|
|
| Posted On |
2012-12-06 |
Incidental Mutation