- Mouse Genome Informatics
(MGI) provides integrated web access to data on the genetics, genomics, and biology of the laboratory mouse.
- Mutant Mouse Regional Resource Centers
(MMRRC) is a repository of mouse stocks and ES cell line collections for the genetics and biomedical research community.
- Ensembl Mouse
provides annotation of the Mus musculus genome based on the NCBI m37 mouse assembly (April 2007, strain C57BL/6J).
provides gene builds for other eukaryotic genomes.
- Online Mendelian Inheritance in Man
(OMIM) is a catalog of human genes and genetic disorders with references to published scientific articles, genetic sequence data and other sources.
- National Center for Biotechnology Information
(NCBI) offers links to many databases including
Structure (with 3-dimensional models of proteins),
is a bioinformatics database of the biology and genome of the model organism Drosophila melanogaster and related insects.
provides a comprehensive, high-quality and freely accessible resource of protein sequence and functional information, while the
Human Protein Reference Database
provides information specifically about the human proteome including protein expression, motifs and domains, function, and protein-protein interactions.
- Useful protein prediction tools include
Simple Modular Architecture Research Tool
(SMART), which produces schematic illustrations of protein motif structure;
which predicts protein stability changes caused by amino acid substitutions;
which predicts subcellular protein localization;
a database of 3D protein structures based on comparative modeling.
- SNPview at GNF is a database of single nucleotide polymorphisms (SNPs)
and simple sequence length polymorphisms (SSLPs) that differ between common Mus musculus strains.
- BioGPS provides access to gene information including expression data across many tissues
and cell lines of mice, rats, and humans.
is a digital atlas of gene expression patterns in the mouse, while
The Allen Institute for Brain Science
provides an excellent interactive, genome-wide image database of gene expression for the adult mouse brain,
the developing mouse brain, the mouse spinal cord and the human cortex.
(Resource of Asian Primary Immunodeficiency Diseases) is a web-based compendium of molecular alterations in primary
- PolyPhen 2
(Polymorphism Phenotyping v2) is an automatic tool for prediction of possible impact of an amino acid substitution
on the structure and function of a human protein. This prediction is based on a number of features comprising the sequence,
phylogenetic and structural information characterizing the substitution.
(Expert Protein Analysis System)
proteomics server of the Swiss Institute of Bioinformatics (SIB) is dedicated to the
analysis of protein sequences and structures as well as 2-D PAGE.