1 |
 |
|
Ltbr
|
armitage
|
6 |
125306571-125313885 bp (-)
|
125312794 |
Unknown (2;0) Autosomal Recessive (2;6)
|
Bone: Lean Fat Ratio (female) - increased Bone: Lean Mass (female) - increased T-independent B cell response defect- decreased TNP-specific IgM to TNP-Ficoll immunization |
2 |
 |
|
Bicc1
|
artemis
|
10 |
70922832-71159700 bp (-)
|
71027954 |
Unknown
|
homeostasis/metabolism life span-post-weaning/aging renal/urinary system |
3 |
 |
|
Prkcq
|
celina2
|
2 |
11172108-11301222 bp (+)
|
11226986 |
Autosomal Recessive (1;4)
|
T-dependent humoral response defect- decreased antibody response to OVA+ alum immunization |
4 |
 |
|
Tlr9
|
Cpg6
|
9 |
106222598-106226883 bp (+)
|
106226593 |
Unknown (2;0)
|
immune system response to injected CpG DNA - decreased TLR signaling defect: TNF production by macrophages |
5 |
 |
|
Cd4
|
craw
|
6 |
124864692-124888221 bp (-)
|
124867746 |
Unknown (3;0)
|
CD4+ T cells - decreased T-dependent humoral response defect- decreased antibody response to OVA+ alum immunization T-dependent humoral response defect- decreased antibody response to rSFV |
6 |
 |
|
Fbxl3
|
delargo
|
14 |
103080239-103099566 bp (-)
|
103089418 |
Autosomal Recessive (4;46) Autosomal Semidominant (1;14)
|
Circadian defect: decrease in circadian active phase duration Circadian defect: decrease in circadian tau activity onset Circadian defect: increase in circadian tau DD by eye Circadian defect: increase in tau chi squared periodogram Circadian rhythm fasting hyperglycemia |
7 |
 |
|
Dock2
|
dew
|
11 |
34226815-34783892 bp (-)
|
34248636 |
Unknown (1;0)
|
CD4+ T cells - decreased CD8+ T cells - decreased T-dependent humoral response defect- decreased antibody response to rSFV |
8 |
 |
|
Slc6a6
|
durango
|
6 |
91684067-91759063 bp (+)
|
91723471 |
Autosomal Recessive (3;40) Autosomal Semidominant (1;4)
|
eye: decrease in BM to ILM thickness vision/eye |
9 |
 |
|
Entpd5
|
eatsy
|
12 |
84373875-84409029 bp (-)
|
84382295 |
Autosomal Recessive (9;41) Autosomal Semidominant (1;4)
|
125-03 Response - increased DSS: sensitive DSS: sensitive day 10 DSS: sensitive day 7 growth/size IgD MFI in B cells - decreased phagocytosis in PECs - decreased |
10 |
 |
|
Atp11c
|
emptyhive
|
X |
60223290-60592698 bp (-)
|
60269987 |
Unknown
|
B cells - decreased hematopoietic system homeostasis/metabolism immune system liver/biliary system reproductive system |
11 |
 |
|
Tnfsf13b
|
Frozen
|
8 |
10006843-10035441 bp (+)
|
10031661 |
Autosomal Recessive (6;46) Autosomal Semidominant (9;97)
|
B cells - decreased CD11c+ DCs - increased CD8+ T cells - increased IgD+ B cells - decreased IgM+ B cells - decreased macrophages - increased neutrophils - increased T cells - increased T-dependent humoral response defect- decreased antibody response to rSFV T-independent B cell response defect- decreased TNP-specific IgM to TNP-Ficoll immunization |
12 |
 |
|
Lepr
|
giant
|
4 |
101717404-101815352 bp (+)
|
101765152 |
Autosomal Recessive (9;61)
|
30 min GTT hyperglycemic Body Weight - increased NK killing - decreased OVA-specific IgE - increased total IgE level - increased |
13 |
 |
|
Map3k8
|
gnostic_gospel
|
18 |
4331327-4353015 bp (-)
|
4333965 |
Unknown (1;0) Autosomal Dominant (1;3)
Autosomal Recessive (5;24)
Autosomal Semidominant (4;16)
|
immune system TLR signaling defect: hyposensitivity to CpG TLR signaling defect: hyposensitivity to LPS TLR signaling defect: hyposensitivity to PAM3CSK4 TLR signaling defect: hyposensitivity to poly I:C |
14 |
 |
|
Agtpbp1
|
gru
|
13 |
59449537-59585227 bp (-)
|
59473746 |
Autosomal Recessive (13;97) Autosomal Semidominant (1;5)
|
behavior/neurological Body Weight - decreased Body Weight (Female) - decreased Body Weight (Male) - decreased growth/size Rotarod time - decreased |
15 |
 |
|
Ptprc
|
guotie
|
1 |
138062861-138175708 bp (-)
|
138068401 |
Autosomal Recessive (49;486) Autosomal Semidominant (7;48)
|
B cells - decreased B:T cells - decreased B1 cells - increased B1a cells in B1 cells - decreased CD4:CD8 - increased CD4+ T cells - decreased CD4+ T cells in CD3+ T cells - increased CD44 MFI in CD8 - decreased CD44 MFI in T cells - decreased CD44+ CD4 T cells - decreased CD44+ CD8 T cells - decreased CD44+ T cells - decreased CD8+ T cells - decreased CD8+ T cells in CD3+ T cells - decreased IgM+ B cells - decreased immune system naive CD8 T cells in CD8 T cells - decreased neutrophils - increased pDCs in CD11c+ cells - increased T cells - decreased T-dependent humoral response defect- decreased antibody response to OVA+ alum immunization T-dependent humoral response defect- decreased antibody response to rSFV |
16 |
 |
|
Fnip1
|
hamel
|
11 |
54438199-54518235 bp (+)
|
54480685 |
Unknown
|
hematopoietic competition - disadvantage hematopoietic system homeostasis/metabolism muscle |
17 |
 |
|
Cd14
|
heedless
|
18 |
36725067-36726654 bp (-)
|
36726171 |
Unknown (1;0)
|
immune system TLR signaling defect: TNF production by macrophages TLR signaling defect: type I IFN production by macrophages |
18 |
 |
|
Naip5
|
inwood3
|
13 |
100211739-100246323 bp (-)
|
100221903 |
Autosomal Recessive (2;9)
|
Nlrc4 inflammasome: low response |
19 |
 |
|
Tg
|
ito2
|
15 |
66670753-66850721 bp (+)
|
66671396 |
Unknown (1;0) Autosomal Recessive (10;60)
Autosomal Semidominant (1;5)
|
Body Weight - decreased Body Weight (Female) - decreased |
20 |
 |
|
Tlr4
|
Lps4
|
4 |
66827584-66930284 bp (+)
|
66841142 |
Unknown (1;0)
|
immune system TLR signaling defect: TNF production by macrophages |
21 |
 |
|
Map3k14
|
lucky
|
11 |
103219762-103267472 bp (-)
|
103249558 |
Unknown (1;0)
|
B cells - decreased hematopoietic system immune system T-dependent humoral response defect- decreased antibody response to rSFV |
22 |
 |
|
Rorc
|
macadamias2
|
3 |
94372831-94397839 bp (+)
|
94387193 |
Autosomal Recessive (17;113)
|
B:T cells - increased B1a cells - increased B1b cells - increased B2 cells - decreased CD4:CD8 - decreased CD4+ T cells - decreased CD4+ T cells in CD3+ T cells - decreased CD44 MFI in CD4 - increased CD44 MFI in CD8 - increased CD8+ T cells in CD3+ T cells - increased effector memory CD4 T cells in CD4 T cells - increased effector memory CD8 T cells in CD8 T cells - increased IgD MFI in B cells - increased macrophages - increased naive CD8 T cells in CD8 T cells - decreased T-dependent humoral response defect- decreased antibody response to OVA+ alum immunization T-dependent humoral response defect- decreased antibody response to rSFV |
23 |
 |
|
Card11
|
May
|
5 |
140872999-141000596 bp (-)
|
140876495 |
Unknown
|
T-independent B cell response defect- decreased TNP-specific IgM to TNP-Ficoll immunization |
24 |
 |
|
Msh6
|
medea
|
17 |
87975050-87990883 bp (+)
|
87980223 |
Autosomal Recessive (2;24)
|
ratio of OVA-specific IgE over the total IgE - increased total IgE level - decreased |
25 |
 |
|
Hr
|
mister_clean
|
14 |
70552212-70573548 bp (+)
|
70560065 |
Unknown
|
skin/coat/nails |
26 |
 |
|
Fgfr4
|
Modest
|
13 |
55152640-55168759 bp (+)
|
55166251 |
Autosomal Semidominant (4;21)
|
B1a cells in B1 cells - decreased Body Weight - decreased Body Weight (DSS Male) - decreased Body Weight (DSS) - decreased |
27 |
 |
|
Inpp5d
|
Orange
|
1 |
87620312-87720507 bp (+)
|
87697546 |
Autosomal Dominant (13;25) Autosomal Recessive (5;8)
Autosomal Semidominant (15;48)
|
B cells - decreased IgD+ B cells - decreased IgM+ B cells - decreased |
28 |
 |
|
Ticam1
|
Pangu
|
17 |
56269319-56276786 bp (-)
|
56276693 |
Unknown (2;0)
|
TLR signaling defect: hyposensitivity to LPS TLR signaling defect: TNF production by macrophages |
29 |
 |
|
Oca2
|
quicksilver
|
7 |
56239760-56536517 bp (+)
|
56324661 |
Unknown
|
pigmentation skin/coat/nails |
30 |
 |
|
Tlr7
|
rsq1
|
X |
167304929-167330558 bp (-)
|
167308286 |
Unknown (1;0)
|
immune system TLR signaling defect: TNF production by macrophages TLR signaling defect: type I IFN production by macrophages |
31 |
 |
|
Prkdc
|
screamer6
|
16 |
15637866-15842235 bp (+)
|
15759605 |
Autosomal Recessive (2;11)
|
effector memory CD4 T cells in CD4 T cells - increased T-dependent humoral response defect- decreased antibody response to rSFV |
32 |
 |
|
Ciita
|
sisal
|
16 |
10488178-10527564 bp (+)
|
10513288 |
Autosomal Recessive (9;49) Autosomal Semidominant (1;4)
|
CD4+ T cells - decreased CD4+ T cells in CD3+ T cells - decreased CD44 MFI in CD4 - increased CD8+ T cells in CD3+ T cells - increased naive CD4 T cells in CD4 T cells - decreased post-MCMV CD4:CD8 - decreased post-MCMV CD8+ T cells in CD3+ T cells - increased T-dependent humoral response defect- decreased antibody response to OVA+ alum immunization T-dependent humoral response defect- decreased antibody response to rSFV |
33 |
 |
|
Slx4
|
slim
|
16 |
3979105-4003770 bp (-)
|
3990910 |
Autosomal Recessive (5;26)
|
Body Weight - decreased Body Weight (Female) - decreased Circadian defect: decrease in final body weight Circadian rhythm growth/size |
34 |
 |
|
Hps5
|
smoky
|
7 |
46760466-46796064 bp (-)
|
46769351 |
Autosomal Recessive (1;2)
|
pigmentation skin/coat/nails |
35 |
 |
|
Dock8
|
snowdrop
|
19 |
24999529-25202432 bp (+)
|
25184941 |
Autosomal Recessive (8;34) Autosomal Semidominant (1;4)
|
T cells - decreased T-dependent humoral response defect- decreased antibody response to OVA+ alum immunization T-dependent humoral response defect- decreased antibody response to rSFV |
36 |
 |
|
Impdh1
|
steve
|
6 |
29200434-29216364 bp (-)
|
29204632 |
Autosomal Recessive (6;38) Autosomal Semidominant (1;4)
|
eye: decrease in BM to ELM thickness eye: decrease in BM to ILM thickness eye: decrease in ONL thickness vision/eye |
37 |
 |
|
Gk5
|
tangyuan
|
9 |
96119362-96184608 bp (+)
|
96150797 |
Autosomal Dominant (1;5) Autosomal Recessive (4;18)
|
B1b cells - decreased skin/coat/nails |
38 |
 |
|
Kbtbd2
|
teeny
|
6 |
56777524-56797813 bp (-)
|
56780389 |
Unknown (1;0) Autosomal Recessive (5;34)
Autosomal Semidominant (1;7)
|
30 min GTT hyperglycemic Body Weight - decreased growth/size liver/biliary system |
39 |
 |
|
Tgm3
|
tortellini
|
2 |
130012349-130050399 bp (+)
|
130024585 |
Unknown (1;0)
|
immune system RVFV susceptibility skin/coat/nails |
40 |
 |
|
Myo6
|
torticollis
|
9 |
80165031-80311729 bp (+)
|
80288217 |
Autosomal Recessive (4;15)
|
behavior/neurological hearing/vestibular/ear nervous system |
41 |
 |
|
Myo15
|
typhoon
|
11 |
60469339-60528369 bp (+)
|
60487425 |
Autosomal Dominant (1;7) Autosomal Recessive (1;5)
|
behavior/neurological |
42 |
 |
|
Clock
|
uhr
|
5 |
76212177-76304548 bp (-)
|
76229554 |
Autosomal Recessive (2;7) Autosomal Semidominant (1;6)
|
Body Weight - increased |
43 |
 |
|
Cd22
|
well
|
7 |
30865402-30880342 bp (-)
|
30877787 |
Unknown
|
B cells - decreased T-independent B cell response defect- decreased TNP-specific IgM to TNP-Ficoll immunization |
44 |
 |
|
Lepr
|
well-upholstered
|
4 |
101717404-101815352 bp (+)
|
101772959 |
Unknown
|
adipose tissue behavior/neurological Body Weight - increased growth/size homeostasis/metabolism reproductive system |
45 |
 |
|
Muc2
|
Winnie
|
7 |
141690340-141754693 bp (+)
|
141699460 |
Unknown
|
DSS: sensitive DSS: sensitive day 7 immune system |
46 |
 |
|
Hr
|
yuanxiao
|
14 |
70552212-70573548 bp (+)
|
70571448 |
Autosomal Recessive (1;4)
|
skin/coat/nails |
47 |
 |
|
Tmprss6
|
zorro
|
15 |
78439668-78468634 bp (-)
|
78464552 |
Unknown
|
embryogenesis growth/size hematopoietic system homeostasis/metabolism iron deficiency reproductive system skin/coat/nails |