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Incidental Mutations

65 incidental mutations are currently displayed, and affect 64 genes.

10 are Possibly Damaging.

19 are Probably Damaging.

26 are Probably Benign.

10 are Probably Null.

4 create premature stop codons.

3 are critical splice junction mutations.

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Mutations in Coding Regions/Splice Sites Identified by Next-Gen Sequencing

[records 1 to 65 of 65] 10 25 50 100 500 1000 per page Full List
	ID	Source UTSW APN	Gene	E-score	Stock #	Gen G0 G0' G1 G2 G3 G3R F1 F2 F3 C0 C1 C2 C3 D1 HES IPS A3	Quality -	Vld Y N ?	Strain	Chr 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 X Y	Position	Mutation A R N D C E Q G H I L K M F P S T W Y V * A R N D C E Q G H I L K M F P S T W Y V *	Ref A C G T -	Var A C G T -	Type makesense missense nonsense start codon destroyed start gained synonymous splice acceptor site splice donor site critical splice acceptor site critical splice donor site splice site large deletion large insertion rearrangement small deletion small insertion exon frame shift intragenic intron utr 3 prime utr 5 prime unclassified	Exon Dist	Zygosity Homo Het Hemi Null	Predicted Effect unknown probably benign probably null possibly damaging probably damaging noncoding transcript silent not run no transcript	PPH Score -	Meta Score	MGI Phenotype available none listed	Posted
1	21932		Ap4b1	0.323	R0136	G1	225	Y		3	103809946	M1T	T	C	start codon destroyed		Het	probably null	1.000	0.963	phenotype	04/12/2013
2	21973		Arg2	0.000	R0136	G1	225	Y		12	79150006	L167P	T	C	missense		Het	probably damaging	1.000	0.775	phenotype	04/12/2013
3	21975		Atxn1	0.000	R0136	G1	225	Y		13	45567169	S417P	A	G	missense		Het	probably damaging	0.990	0.105	phenotype	04/12/2013
4	21928		Baz2b	0.269	R0136	G1	225	Y		2	59901954	V1949A	A	G	missense		Het	probably benign	0.221	0.083	phenotype	04/12/2013
5	21951		Bcl3	0.000	R0136	G1	133	Y		7	19809569	V324A	A	G	missense		Het	probably damaging	0.997	0.322	phenotype	04/12/2013
6	21953		Btbd10	0.320	R0136	G1	225	Y		7	113329878	S230T	A	T	missense		Het	possibly damaging	0.543	0.155		04/12/2013
7	21938		Camta1	0.592	R0136	G1	225	Y		4	151078969	S1479P	A	G	missense		Het	probably damaging	0.990	0.318	phenotype	04/12/2013
8	21949		Cd69	0.096	R0136	G1	225	Y		6	129270062	S64N	C	T	missense		Het	probably benign	0.006	0.110	phenotype	04/12/2013
9	21926		Col5a1	1.000	R0136	G1	225	Y		2	28024831	L153P	T	C	missense		Het	probably damaging	1.000	0.695	phenotype	04/12/2013
10	21927		Crat	0.137	R0136	G1	225	Y		2	30407030	V304L	C	A	missense		Het	probably benign	0.000	0.117	phenotype	04/12/2013
11	21981		Csmd3	0.000	R0136	G1	98	Y		15	47847131	T1687A	T	C	missense		Het	probably benign	0.078	0.072		04/12/2013
12	21979		Dnah1	0.000	R0136	G1	117	Y		14	31276158	G2574D	C	T	missense		Het	probably damaging	1.000	0.700	phenotype	04/12/2013
13	21990		Fau		R0136	G1	225	Y		19	6059180	V86A	T	C	missense		Het	possibly damaging	0.611	0.107	phenotype	04/12/2013
14	21986		Garem1	0.113	R0136	G1	225	Y		18	21129991	S589R	T	G	missense		Het	probably damaging	0.960	0.065	phenotype	04/12/2013
15	21933		Gbp3	0.000	R0136	G1	225	N		3	142564101		T	G	splice site		Het	probably null			phenotype	04/12/2013
16	21924		Gin1	0.000	R0136	G1	225	Y		1	97783016	S141R	T	A	missense		Het	possibly damaging	0.858	0.236		04/12/2013
17	21952		Gtf2h1	0.966	R0136	G1	225	N		7	46815416	Q419L	A	T	missense		Het	possibly damaging	0.488			04/12/2013
18	21929		Hipk3	0.000	R0136	G1	225	Y		2	104439293	I517T	A	G	missense		Het	probably benign	0.021	0.090	phenotype	04/12/2013
19	21962		Hivep2	0.891	R0136	G1	225	Y		10	14131878	S1407P	T	C	missense		Het	probably benign	0.044	0.071	phenotype	04/12/2013
20	21976		Hnrnpk	0.877	R0136	G1	225	Y		13	58395177	D211E	G	T	missense		Het	probably benign	0.010	0.090	phenotype	04/12/2013
21	21991		Hnrnpul2	0.453	R0136	G1	225	Y		19	8826801	L588P	T	C	missense		Het	probably damaging	1.000	0.487		04/12/2013
22	21921		Il18rap	0.000	R0136	G1	225	Y		1	40525058	H112L	A	T	missense		Het	probably benign	0.035	0.084	phenotype	04/12/2013
23	21957		Itgb1	1.000	R0136	G1	225	Y		8	128722854	Y585D	T	G	missense		Het	possibly damaging	0.956	0.840	phenotype	04/12/2013
24	21983		Kmt2d	1.000	R0136	G1	225	Y		15	98854278		C	T	unclassified		Het	probably benign		0.063	phenotype	04/12/2013
25	21936		Map7d1	0.808	R0136	G1	177	N		4	126236631		A	T	critical splice donor site	2 bp	Het	probably null				04/12/2013
26	21988		Me2	0.000	R0136	G1	225	Y		18	73770673	S575P	A	G	missense		Het	probably benign	0.000	0.076	phenotype	04/12/2013
27	21943		Med13l	0.960	R0136	G1	225	Y		5	118724050	T353A	A	G	missense		Het	probably benign	0.151	0.059	phenotype	04/12/2013
28	21965		Mgat4b	0.000	R0136	G1	192	Y		11	50231081	V143A	T	C	missense		Het	possibly damaging	0.911	0.120	phenotype	04/12/2013
29	21945		Mlxip	0.318	R0136	G1	225	Y		5	123442306	W211R	T	A	missense		Het	probably damaging	0.999	0.905	phenotype	04/12/2013
30	261802		Morc2a	1.000	R0136	G1	225	N		11	3685907		T	G	intron	25 bp	Het	probably null			phenotype	02/04/2015
31	65804		Muc4	0.117	R0136	G1	225	N		16	32750195		A	T	critical splice acceptor site		Het	probably benign		0.090	phenotype	08/19/2013
32	21922		Ndufa10	1.000	R0136	G1	225	Y		1	92463128	Y233*	A	T	nonsense		Het	probably null		0.976	phenotype	04/12/2013
33	21970		Nek8	0.912	R0136	G1	211	Y		11	78171207	S237N	C	T	missense		Het	probably benign	0.014	0.082	phenotype	04/12/2013
34	21989		Neto1	0.061	R0136	G1	225	Y		18	86461320	R211Q	G	A	missense		Het	probably benign	0.168	0.081	phenotype	04/12/2013
35	21954		Nfatc2ip	0.262	R0136	G1	225	Y		7	126391335	S165P	A	G	missense		Het	probably benign	0.108	0.115	phenotype	04/12/2013
36	21941		Nsd2	0.842	R0136	G1	225	Y		5	33855536	K404E	A	G	missense		Het	possibly damaging	0.889	0.062	phenotype	04/12/2013
37	21956		Nsd3	0.376	R0136	G1	225	Y		8	25659854	E352*	G	T	nonsense		Het	probably null		0.976	phenotype	04/12/2013
38	60923		Nudt9	0.117	R0136	G1	118	N		5	104047106	T23A	A	G	missense		Het	probably benign	0.000	0.096	phenotype	07/24/2013
39	21968		Olfr394	0.195	R0136	G1	225	N		11	73887785	M196V	T	C	missense		Het	probably benign	0.002	0.090	phenotype	04/12/2013
40	21969		Olfr394	0.195	R0136	G1	225	N		11	73887830	V181I	C	T	missense		Het	probably benign	0.113	0.090	phenotype	04/12/2013
41	21959		Olfr983	0.062	R0136	G1	225	Y		9	40092019	*312Q	A	G	makesense		Het	probably null		0.976	phenotype	04/12/2013
42	21934		Patj	0.000	R0136	G1	225	Y		4	98667648	Q297K	C	A	missense		Het	probably damaging	0.995	0.634	phenotype	04/12/2013
43	21978		Pelo	0.928	R0136	G1	225	Y		13	115088903	C40*	A	T	nonsense		Het	probably null		0.976	phenotype	04/12/2013
44	21982		Pnpla3	0.000	R0136	G1	225	Y		15	84174478		G	A	critical splice donor site	1 bp	Het	probably null		0.947	phenotype	04/12/2013
45	21937		Pramel1	0.000	R0136	G1	225	Y		4	143397446	N230K	C	A	missense		Het	probably damaging	0.998	0.647		04/12/2013
46	21950		Psg20	0.063	R0136	G1	225	Y		7	18682507	L228R	A	C	missense		Het	probably damaging	0.978	0.533		04/12/2013
47	21946		Rsph10b	0.074	R0136	G1	225	Y		5	143959821	F44L	T	C	missense		Het	probably benign	0.048	0.064		04/12/2013
48	21923		Sept2	0.907	R0136	G1	120	Y		1	93507050	G358R	G	A	missense		Het	possibly damaging	0.568	0.101		04/12/2013
49	98735		Slamf7	0.050	R0136	G1	225	N		1	171648931		G	A	unclassified		Het	probably benign			phenotype	01/09/2014
50	21984		Slc12a8	0.000	R0136	G1	225	Y		16	33608213	D297G	A	G	missense		Het	probably damaging	0.999	0.371	phenotype	04/12/2013
51	21961		Slc17a5	0.165	R0136	G1	211	N		9	78578674	A43V	G	A	missense		Het	probably damaging	1.000	0.249	phenotype	04/12/2013
52	21985		Slc22a1	0.000	R0136	G1	225	Y		17	12662596	F335L	A	T	missense		Het	probably benign	0.030	0.135	phenotype	04/12/2013
53	21940		Slc26a5	0.000	R0136	G1	225	Y		5	21834347	N216S	T	C	missense		Het	probably damaging	0.999	0.119	phenotype	04/12/2013
54	21948		Snrnp27	1.000	R0136	G1	225	Y		6	86676205	S144G	T	C	missense		Het	probably benign	0.074	0.090	phenotype	04/12/2013
55	21971		Spata20	0.245	R0136	G1	189	Y		11	94480609	D643V	T	A	missense		Het	probably damaging	1.000	0.973		04/12/2013
56	21987		Spata24	0.633	R0136	G1	225	Y		18	35660462	K99R	T	C	missense		Het	probably damaging	0.999	0.092		04/12/2013
57	21963		Taar5	0.083	R0136	G1	211	Y		10	23971709	Y335C	A	G	missense		Het	probably damaging	1.000	0.130	phenotype	04/12/2013
58	21925		Tpr	1.000	R0136	G1	209	Y		1	150430595	H1540R	A	G	missense		Het	probably benign	0.012	0.081	phenotype	04/12/2013
59	21947		Vmn1r27	0.150	R0136	G1	225	Y		6	58215719	F100S	A	G	missense		Het	possibly damaging	0.564	0.179		04/12/2013
60	60924		Vmn2r37	0.085	R0136	G1	100	N		7	9217783	Y360*	A	T	nonsense		Het	probably null				07/24/2013
61	21935		Ybx1	1.000	R0136	G1	205	Y		4	119282354	R36L	C	A	missense		Het	possibly damaging	0.575	0.144	phenotype	04/12/2013
62	21977		Zfp369	0.092	R0136	G1	225	Y		13	65297202	K720E	A	G	missense		Het	probably benign	0.076	0.127		04/12/2013
63	21958		Zfp599	0.090	R0136	G1	225	Y		9	22249742	S376P	A	G	missense		Het	probably benign	0.131	0.090		04/12/2013
64	21980		Zic2	0.893	R0136	G1	225	N		14	122476541	E289G	A	G	missense		Het	probably damaging	0.963		phenotype	04/12/2013
65	21967		Zzef1	0.000	R0136	G1	225	Y		11	72821851	V199A	T	C	missense		Het	probably benign	0.000	0.076		04/12/2013
[records 1 to 65 of 65]