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Incidental Mutations

100 incidental mutations are currently displayed, and affect 99 genes.

17 are Possibly Damaging.

47 are Probably Damaging.

24 are Probably Benign.

11 are Probably Null.

5 create premature stop codons.

3 are critical splice junction mutations.

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Mutations in Coding Regions/Splice Sites Identified by Next-Gen Sequencing

[records 1 to 100 of 100] 10 25 50 100 500 1000 per page Full List
	ID	Source UTSW APN	Gene	E-score	Stock #	Gen G0 G0' G1 G2 G3 G3R F1 F2 F3 C0 C1 C2 C3 D1 HES IPS A3	Quality -	Vld Y N ?	Strain	Chr 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 X Y	Position	Mutation A R N D C E Q G H I L K M F P S T W Y V * A R N D C E Q G H I L K M F P S T W Y V *	Ref A C G T -	Var A C G T -	Type makesense missense nonsense start codon destroyed start gained synonymous splice acceptor site splice donor site critical splice acceptor site critical splice donor site splice site large deletion large insertion rearrangement small deletion small insertion exon frame shift intragenic intron utr 3 prime utr 5 prime unclassified	Exon Dist	Zygosity Homo Het Hemi Null	Predicted Effect unknown probably benign probably null possibly damaging probably damaging noncoding transcript silent not run no transcript	PPH Score -	Meta Score	MGI Phenotype available none listed	Posted
1	167517		1700003E16Rik	0.618	R1522	G1	225	N		6	83162586	S498P	T	C	missense		Het	probably damaging	0.962			04/13/2014
2	167505		3100002H09Rik	0.064	R1522	G1	225	N		4	124610694	W22R	A	G	missense		Het	probably damaging	0.985			04/13/2014
3	167484		AA986860	0.066	R1522	G1	225	N		1	130743094	E351G	A	G	missense		Het	probably damaging	1.000			04/13/2014
4	167591		Acsl5	0.000	R1522	G1	225	N		19	55280492	V195A	T	C	missense		Het	probably benign	0.013		phenotype	04/13/2014
5	167573		Adamts10	0.452	R1522	G1	225	N		17	33537319	D312G	A	G	missense		Het	probably benign	0.402		phenotype	04/13/2014
6	167563		Adgrb1	0.000	R1522	G1	142	N		15	74580617	M211V	A	G	missense		Het	probably damaging	0.996		phenotype	04/13/2014
7	167546		Ankfy1	1.000	R1522	G1	225	N		11	72755867	R859*	C	T	nonsense		Het	probably null			phenotype	04/13/2014
8	167586		Atp8b1	0.000	R1522	G1	225	N		18	64550432	I742L	T	A	missense		Het	probably benign	0.005		phenotype	04/13/2014
9	167551		B3galnt2	1.000	R1522	G1	225	N		13	13970769	V89E	T	A	missense		Het	probably damaging	1.000		phenotype	04/13/2014
10	167523		BC024978	0.110	R1522	G1	225	N		7	27202680	H244R	A	G	missense		Het	probably damaging	0.998			04/13/2014
11	167485		Brinp3	0.235	R1522	G1	225	N		1	146901890	T692P	A	C	missense		Het	probably damaging	0.988		phenotype	04/13/2014
12	167561		C9	0.000	R1522	G1	225	N		15	6486762	F349I	T	A	missense		Het	probably damaging	0.995		phenotype	04/13/2014
13	167532		Cacna1a	0.900	R1522	G1	225	N		8	84633433	M1976K	T	A	missense		Het	probably benign	0.001		phenotype	04/13/2014
14	167502		Ccdc180	0.000	R1522	G1	225	N		4	45927975	V1170A	T	C	missense		Het	possibly damaging	0.923		phenotype	04/13/2014
15	167567		Celsr1	0.757	R1522	G1	225	N		15	85931276	V1846A	A	G	missense		Het	probably benign	0.016		phenotype	04/13/2014
16	167533		Ces1f	0.074	R1522	G1	225	N		8	93271889	Y160N	A	T	missense		Het	possibly damaging	0.516	0.179		04/13/2014
17	167489		Cfap45	0.195	R1522	G1	225	N		1	172540572	E377G	A	G	missense		Het	probably damaging	1.000			04/13/2014
18	167501		Clca3a1	0.081	R1522	G1	225	N		3	144755171	M240L	T	A	missense		Het	probably benign	0.006			04/13/2014
19	167512		Clnk	0.071	R1522	G1	225	N		5	38794966	T10M	G	A	missense		Het	probably damaging	1.000		phenotype	04/13/2014
20	167493		Cntrl	0.839	R1522	G1	225	N		2	35155279	I781K	T	A	missense		Het	possibly damaging	0.827	0.167	phenotype	04/13/2014
21	167574		Col11a2	0.921	R1522	G1	225	N		17	34055254	G375S	G	A	missense		Het	probably damaging	1.000		phenotype	04/13/2014
22	167538		Col6a5	0.910	R1522	G1	225	N		9	105939994	I373F	T	A	missense		Het	unknown			phenotype	04/13/2014
23	167585		Dmxl1	0.947	R1522	G1	225	N		18	49852367	A227V	C	T	missense		Het	probably benign	0.046		phenotype	04/13/2014
24	167496		Dok5	0.000	R1522	G1	225	N		2	170732132	N4D	A	G	missense		Het	probably benign	0.133		phenotype	04/13/2014
25	167583		Dpysl3	0.499	R1522	G1	225	N		18	43363557	V138D	A	T	missense		Het	probably damaging	1.000		phenotype	04/13/2014
26	167557		Efs	0.155	R1522	G1	225	N		14	54919715	Y380N	A	T	missense		Het	probably damaging	1.000		phenotype	04/13/2014
27	167571		Eme2	0.086	R1522	G1	175	N		17	24892918	S263F	G	A	missense		Het	probably damaging	1.000	0.332	phenotype	04/13/2014
28	167483		Farp2	0.000	R1522	G1	225	N		1	93618553	Q855R	A	G	missense		Het	possibly damaging	0.785		phenotype	04/13/2014
29	167499		Fcrls	0.072	R1522	G1	225	N		3	87256707	S372A	A	C	missense		Het	possibly damaging	0.640		phenotype	04/13/2014
30	167539		Gadl1	0.082	R1522	G1	225	N		9	115944229	A113V	C	T	missense		Het	probably damaging	0.996			04/13/2014
31	167514		Gatsl2	0.066	R1522	G1	201	N		5	134125887	S43R	T	G	missense		Het	probably damaging	0.973			04/13/2014
32	167588		Gda	0.000	R1522	G1	225	N		19	21412539	E219D	T	A	missense		Het	probably benign	0.000		phenotype	04/13/2014
33	167542		Gli1	0.000	R1522	G1	178	N		10	127332577	M469K	A	T	missense		Het	probably damaging	0.993		phenotype	04/13/2014
34	167487		Gm4847	0.098	R1522	G1	225	N		1	166641650	S148R	A	T	missense		Het	probably damaging	0.996			04/13/2014
35	167492		Golga2	0.781	R1522	G1	201	N		2	32302204	V325A	T	C	missense		Het	probably benign	0.012		phenotype	04/13/2014
36	167530		Hpf1	0.000	R1522	G1	225	N		8	60896749	D137G	A	G	missense		Het	probably damaging	0.965			04/13/2014
37	167559		Htr2a	0.074	R1522	G1	225	N		14	74705853	S291*	C	G	nonsense		Het	probably null			phenotype	04/13/2014
38	167568		Itga5	1.000	R1522	G1	225	N		15	103356782	Q233*	G	A	nonsense		Het	probably null			phenotype	04/13/2014
39	167515		Jazf1	0.000	R1522	G1	225	N		6	52812183	R102L	C	A	missense		Het	probably damaging	0.977		phenotype	04/13/2014
40	167579		Kif6	0.105	R1522	G1	225	N		17	49714113	L322R	T	G	missense		Het	probably damaging	0.986		phenotype	04/13/2014
41	167556		Ktn1	0.000	R1522	G1	225	N		14	47667416	K217T	A	C	missense		Het	probably damaging	1.000		phenotype	04/13/2014
42	167527		Lig4	1.000	R1522	G1	225	N		8	9973012	V256E	A	T	missense		Het	possibly damaging	0.699	0.179	phenotype	04/13/2014
43	167543		Lrp1	1.000	R1522	G1	225	N		10	127567364	D2113E	G	T	missense		Het	probably damaging	0.996		phenotype	04/13/2014
44	167544		Lrp1	1.000	R1522	G1	154	N		10	127575286	D1399E	A	T	missense		Het	probably benign	0.036		phenotype	04/13/2014
45	167509		Mmel1	0.164	R1522	G1	209	N		4	154894986	E717G	A	G	missense		Het	probably damaging	1.000		phenotype	04/13/2014
46	167490		Mndal	0.125	R1522	G1	225	N		1	173871466	P155H	G	T	missense		Het	possibly damaging	0.681			04/13/2014
47	167547		Mycbpap	0.386	R1522	G1	225	N		11	94511623		A	G	critical splice donor site	2 bp	Het	probably null		0.949		04/13/2014
48	167540		Nedd1	0.962	R1522	G1	225	N		10	92719614	E3G	T	C	missense		Het	probably damaging	1.000	0.142		04/13/2014
49	167497		Nlgn1	0.000	R1522	G1	225	N		3	25435909	N551K	A	T	missense		Het	probably damaging	1.000		phenotype	04/13/2014
50	167518		Nup210	0.000	R1522	G1	193	N		6	91069166	P595L	G	A	missense		Het	possibly damaging	0.845		phenotype	04/13/2014
51	167576		Olfr117	0.084	R1522	G1	225	N		17	37659770	C188S	A	T	missense		Het	probably damaging	1.000		phenotype	04/13/2014
52	262822		Olfr1302	0.072	R1522	G1	225	N		2	111780348		A	T	synonymous		Het	probably null			phenotype	02/04/2015
53	167570		Olfr199	0.071	R1522	G1	225	N		16	59215984	T210P	T	G	missense		Het	probably damaging	0.998		phenotype	04/13/2014
54	167526		Olfr477	0.206	R1522	G1	225	N		7	107990533	H56R	A	G	missense		Het	probably benign	0.269	0.090	phenotype	04/13/2014
55	167525		Olfr697	0.079	R1522	G1	225	N		7	106741005	C310R	A	G	missense		Het	probably benign	0.034		phenotype	04/13/2014
56	167545		Pank3	0.202	R1522	G1	225	N		11	35781681	V304M	G	A	missense		Het	probably benign	0.448		phenotype	04/13/2014
57	167482		Phf3	0.000	R1522	G1	225	N		1	30805648	T1410I	G	A	missense		Het	probably benign	0.048		phenotype	04/13/2014
58	167516		Ppm1k	0.076	R1522	G1	225	N		6	57525157	I7T	A	G	missense		Het	possibly damaging	0.480		phenotype	04/13/2014
59	167520		Ppp1r12c	0.175	R1522	G1	174	N		7	4497425	D73G	T	C	missense		Het	probably damaging	0.999		phenotype	04/13/2014
60	167582		Prelid2	0.000	R1522	G1	225	N		18	41881267	M165L	T	G	missense		Het	probably benign	0.000			04/13/2014
61	167581		Prkd3	0.177	R1522	G1	225	N		17	78952696	L826R	A	C	missense		Het	probably damaging	1.000		phenotype	04/13/2014
62	167577		Ptchd4	0.064	R1522	G1	225	N		17	42503542	N778I	A	T	missense		Het	probably damaging	0.998			04/13/2014
63	167580		Ptprm	0.000	R1522	G1	210	N		17	66693871	D1063G	T	C	missense		Het	possibly damaging	0.908		phenotype	04/13/2014
64	167534		Rab27a	0.313	R1522	G1	225	N		9	73075482	T23N	C	A	missense		Het	probably damaging	0.997		phenotype	04/13/2014
65	167553		Rasgrf2	0.210	R1522	G1	225	N		13	91896086	F949L	A	T	missense		Het	probably benign	0.003		phenotype	04/13/2014
66	167510		Rbm33	1.000	R1522	G1	225	N		5	28337004	N68D	A	G	missense		Het	probably damaging	0.999			04/13/2014
67	167486		Rgl1	0.255	R1522	G1	225	N		1	152586533	L109Q	A	T	missense		Het	probably damaging	1.000		phenotype	04/13/2014
68	167503		Rnf20	1.000	R1522	G1	225	N		4	49638197	N103S	A	G	missense		Het	possibly damaging	0.924	0.071	phenotype	04/13/2014
69	167513		Sbno1	1.000	R1522	G1	225	N		5	124392612	L875F	G	A	missense		Het	probably damaging	1.000			04/13/2014
70	167566		Scube1	0.165	R1522	G1	225	N		15	83628076		T	A	critical splice acceptor site		Het	probably null			phenotype	04/13/2014
71	167500		Selenbp1	0.000	R1522	G1	129	N		3	94937358	V109M	G	A	missense		Het	probably damaging	1.000		phenotype	04/13/2014
72	167550		Serpina3c	0.000	R1522	G1	225	N		12	104151546	I178F	T	A	missense		Het	probably damaging	0.999			04/13/2014
73	167565		Shisa8	0.000	R1522	G1	225	N		15	82208501	G63D	C	T	missense		Het	probably damaging	0.983			04/13/2014
74	167536		Snx14	1.000	R1522	G1	225	N		9	88402224	R464G	T	C	missense		Het	possibly damaging	0.522		phenotype	04/13/2014
75	167528		Snx25	1.000	R1522	G1	225	N		8	46124082	M1K	A	T	start codon destroyed		Het	probably null	0.883	0.897		04/13/2014
76	167590		Sorcs3	0.149	R1522	G1	225	N		19	48706009	T574K	C	A	missense		Het	possibly damaging	0.842		phenotype	04/13/2014
77	167549		Syne2	0.329	R1522	G1	204	N		12	76103783	E6528G	A	G	missense		Het	probably damaging	0.977		phenotype	04/13/2014
78	167521		Syt5	0.147	R1522	G1	225	N		7	4540246	E338G	T	C	missense		Het	probably damaging	0.974		phenotype	04/13/2014
79	167541		Tbk1	1.000	R1522	G1	225	N		10	121551318	K691E	T	C	missense		Het	probably benign	0.064		phenotype	04/13/2014
80	167529		Tenm3	0.616	R1522	G1	225	N		8	48395576	T11I	G	A	missense		Het	probably damaging	0.997		phenotype	04/13/2014
81	167554		Thrb	0.544	R1522	G1	225	N		14	18002597	H87R	A	G	missense		Het	probably damaging	1.000		phenotype	04/13/2014
82	167504		Tlr4	0.000	R1522	G1	225	N		4	66839696	M242K	T	A	missense		Het	possibly damaging	0.802		phenotype	04/13/2014
83	167569		Tm4sf19	0.072	R1522	G1	225	N		16	32406002	M56T	T	C	missense		Het	possibly damaging	0.605			04/13/2014
84	167498		Tmem212	0.077	R1522	G1	209	N		3	27886471	R66*	T	A	nonsense		Het	probably null				04/13/2014
85	167506		Tmem39b	0.378	R1522	G1	225	N		4	129684482	D315E	G	T	missense		Het	probably benign	0.301			04/13/2014
86	167575		Tnxb	0.000	R1522	G1	225	N		17	34718638	F3834L	T	C	missense		Het	probably damaging	0.996		phenotype	04/13/2014
87	167584		Trim36	0.306	R1522	G1	225	N		18	46186183	L225*	A	T	nonsense		Het	probably null			phenotype	04/13/2014
88	167537		Trim42	0.074	R1522	G1	178	N		9	97365679	H321Q	A	T	missense		Het	probably damaging	1.000	0.647	phenotype	04/13/2014
89	167562		Trio	1.000	R1522	G1	225	N		15	27732640	Q3052K	G	T	missense		Het	probably benign	0.283		phenotype	04/13/2014
90	167589		Trpm3	0.104	R1522	G1	225	N		19	22978334	I1091T	T	C	missense		Het	probably benign	0.388		phenotype	04/13/2014
91	167564		Tst		R1522	G1	212	N		15	78399943	E228G	T	C	missense		Het	possibly damaging	0.667		phenotype	04/13/2014
92	167495		Ttn	1.000	R1522	G1	225	N		2	76871716		T	C	unclassified		Het	probably benign			phenotype	04/13/2014
93	167488		Uap1	0.722	R1522	G1	203	N		1	170150941		A	C	critical splice donor site	2 bp	Het	probably null				04/13/2014
94	167491		Ush2a	0.632	R1522	G1	225	N		1	188797814	S3267P	T	C	missense		Het	possibly damaging	0.938		phenotype	04/13/2014
95	167519		Usp5	1.000	R1522	G1	210	N		6	124825166	T38A	T	C	missense		Het	probably benign	0.000		phenotype	04/13/2014
96	167511		Uvssa	0.096	R1522	G1	225	N		5	33387808	Q84L	A	T	missense		Het	probably damaging	1.000		phenotype	04/13/2014
97	167522		Vmn1r159		R1522	G1	143	N		7	22843268	H113P	T	G	missense		Het	probably damaging	0.983			04/13/2014
98	167508		Vps13d	1.000	R1522	G1	225	N		4	145098172		A	T	splice site		Het	probably null			phenotype	04/13/2014
99	167592		Zfp182	0.000	R1522	G1	222	N		X	21031560	I166L	T	A	missense		Het	probably benign	0.006		phenotype	04/13/2014
100	167572		Zfp811	0.058	R1522	G1	225	N		17	32797648	Y472N	A	T	missense		Het	probably damaging	1.000			04/13/2014
[records 1 to 100 of 100]