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Incidental Mutations

65 incidental mutations are currently displayed, and affect 65 genes.

11 are Possibly Damaging.

28 are Probably Damaging.

20 are Probably Benign.

6 are Probably Null.

1 create premature stop codons.

4 are critical splice junction mutations.

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Mutations in Coding Regions/Splice Sites Identified by Next-Gen Sequencing

[records 1 to 65 of 65] 10 25 50 100 500 1000 per page Full List
	ID	Source UTSW APN	Gene	E-score	Stock #	Gen G0 G0' G1 G2 G3 G3R F1 F2 F3 C0 C1 C2 C3 D1 HES IPS A3	Quality -	Vld Y N ?	Strain	Chr 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 X Y	Position	Mutation A R N D C E Q G H I L K M F P S T W Y V * A R N D C E Q G H I L K M F P S T W Y V *	Ref A C G T -	Var A C G T -	Type makesense missense nonsense start codon destroyed start gained synonymous splice acceptor site splice donor site critical splice acceptor site critical splice donor site splice site large deletion large insertion rearrangement small deletion small insertion exon frame shift intragenic intron utr 3 prime utr 5 prime unclassified	Exon Dist	Zygosity Homo Het Hemi Null	Predicted Effect unknown probably benign probably null possibly damaging probably damaging noncoding transcript silent not run no transcript	PPH Score -	Meta Score	MGI Phenotype available none listed	Posted
1	239486		2700062C07Rik	0.814	R2212	G1	225	N		18	24470920	Y6C	A	G	missense		Het	probably damaging	1.000			10/15/2014
2	239472		3425401B19Rik	0.095	R2212	G1	225	N		14	32661602	Q802L	T	A	missense		Het	probably benign	0.332	0.090		10/15/2014
3	239470		Adarb2	0.000	R2212	G1	206	N		13	8752618	F643S	T	C	missense		Het	probably damaging	0.999	0.646	phenotype	10/15/2014
4	239482		Angptl4	0.000	R2212	G1	225	N		17	33775418	I401T	A	G	missense		Het	probably damaging	0.994		phenotype	10/15/2014
5	239453		Ap2a2	0.315	R2212	G1	225	N		7	141598776	N105K	T	A	missense		Het	probably benign	0.045	0.240	phenotype	10/15/2014
6	239432		Atp8b4	0.066	R2212	G1	225	N		2	126375757	W613L	C	A	missense		Het	probably damaging	1.000	0.802	phenotype	10/15/2014
7	239463		Coq10a	0.183	R2212	G1	225	N		10	128365129	V93A	A	G	missense		Het	possibly damaging	0.738	0.064		10/15/2014
8	239481		Cyp4f39	0.299	R2212	G1	225	N		17	32487063	E376V	A	T	missense		Het	possibly damaging	0.617		phenotype	10/15/2014
9	239456		Deup1	0.000	R2212	G1	225	N		9	15599843	D213E	A	T	missense		Het	probably benign	0.005			10/15/2014
10	239483		Ehmt2	1.000	R2212	G1	225	N		17	34899365	S39G	A	G	missense		Het	probably benign	0.000		phenotype	10/15/2014
11	239422		Eya1	0.823	R2212	G1	225	N		1	14274209		T	A	critical splice acceptor site		Het	probably null		0.972	phenotype	10/15/2014
12	239436		Fam92a	0.000	R2212	G1	174	N		4	12171696		A	G	critical splice donor site	2 bp	Het	probably null				10/15/2014
13	239429		Fcna	0.000	R2212	G1	225	N		2	25627493	P49A	G	C	missense		Het	probably damaging	0.996	0.363	phenotype	10/15/2014
14	239471		Flnb	1.000	R2212	G1	217	N		14	7881652		AAGGAG	AAG	small deletion		Het	probably benign			phenotype	10/15/2014
15	239468		Fscn2	0.167	R2212	G1	139	N		11	120361591		G	T	start gained		Het	probably benign			phenotype	10/15/2014
16	239441		Gckr	0.000	R2212	G1	225	N		5	31300867		T	A	critical splice donor site	2 bp	Het	probably null		0.948	phenotype	10/15/2014
17	239477		Golgb1	0.822	R2212	G1	225	N		16	36887347	K68E	A	G	missense		Het	probably damaging	0.999	0.163	phenotype	10/15/2014
18	239484		H2-M11	0.061	R2212	G1	225	N		17	36548930	V272M	G	A	missense		Het	probably damaging	1.000			10/15/2014
19	239460		Hace1	0.386	R2212	G1	225	N		10	45648675	D234E	T	A	missense		Het	possibly damaging	0.499	0.241	phenotype	10/15/2014
20	239423		Il18r1	0.000	R2212	G1	221	N		1	40491067	D318V	A	T	missense		Het	probably damaging	1.000	0.553	phenotype	10/15/2014
21	239448		Il4i1	0.000	R2212	G1	225	N		7	44836658	L22P	T	C	missense		Het	probably damaging	0.992	0.638	phenotype	10/15/2014
22	239474		Kcnq3	0.129	R2212	G1	225	N		15	66020293	F411Y	A	T	missense		Het	probably benign	0.000		phenotype	10/15/2014
23	239427		Kcnt2	0.125	R2212	G1	225	N		1	140530800	Y775C	A	G	missense		Het	probably damaging	0.999		phenotype	10/15/2014
24	239475		Krt84	0.148	R2212	G1	225	N		15	101532538	V73G	A	C	missense		Het	probably benign	0.013		phenotype	10/15/2014
25	239465		Lcp2	1.000	R2212	G1	225	N		11	34070995	D117A	A	C	missense		Het	probably benign	0.136		phenotype	10/15/2014
26	239425		Lemd1	0.060	R2212	G1	225	N		1	132228286	T22K	C	A	missense		Het	probably benign	0.109			10/15/2014
27	239426		Mdm4	1.000	R2212	G1	225	N		1	132994522	D294G	T	C	missense		Het	probably damaging	1.000		phenotype	10/15/2014
28	239485		Mep1a	0.000	R2212	G1	225	N		17	43477263	A634V	G	A	missense		Het	probably benign	0.021		phenotype	10/15/2014
29	239478		Myh15	0.306	R2212	G1	225	N		16	49138732	D989G	A	G	missense		Het	probably benign	0.023	0.090		10/15/2014
30	239464		Myo1g	0.000	R2212	G1	225	N		11	6517870	H188Q	G	T	missense		Het	possibly damaging	0.885	0.121	phenotype	10/15/2014
31	239435		Nsmaf	0.085	R2212	G1	225	N		4	6396732	L918F	C	A	missense		Het	probably damaging	0.991		phenotype	10/15/2014
32	239466		Olfr1396	0.067	R2212	G1	225	N		11	49113216	C170Y	C	T	missense		Het	probably damaging	0.998		phenotype	10/15/2014
33	239449		Olfr561	0.078	R2212	G1	225	N		7	102774755	L77P	T	C	missense		Het	possibly damaging	0.775	0.179	phenotype	10/15/2014
34	239450		Olfr635	0.102	R2212	G1	225	N		7	103979402	L76P	T	C	missense		Het	probably damaging	0.978	0.235	phenotype	10/15/2014
35	239457		Olfr963	0.078	R2212	G1	225	N		9	39669228	M57K	T	A	missense		Het	probably damaging	1.000		phenotype	10/15/2014
36	239424		Pfkfb2	0.000	R2212	G1	225	N		1	130707532	N97K	A	T	missense		Het	probably damaging	1.000		phenotype	10/15/2014
37	239462		Phlda1	0.000	R2212	G1	225	N		10	111507168	E255V	A	T	missense		Het	probably damaging	1.000		phenotype	10/15/2014
38	239430		Pla2g4f	0.064	R2212	G1	225	N		2	120303106	S579G	T	C	missense		Het	probably benign	0.000	0.093		10/15/2014
39	239446		Plcz1	0.000	R2212	G1	225	N		6	140002081	R525Q	C	T	missense		Het	probably damaging	0.984	0.647	phenotype	10/15/2014
40	239487		Ppargc1b	0.384	R2212	G1	225	N		18	61311220	Q291*	G	A	nonsense		Het	probably null			phenotype	10/15/2014
41	239443		Ppef2	0.000	R2212	G1	225	N		5	92228722	S649R	T	G	missense		Het	probably damaging	0.967	0.089	phenotype	10/15/2014
42	239454		Ppp1r3b	0.351	R2212	G1	225	N		8	35384225	T73A	A	G	missense		Het	possibly damaging	0.921		phenotype	10/15/2014
43	239459		Prss43	0.061	R2212	G1	225	N		9	110829464	Q277H	G	C	missense		Het	probably damaging	0.996	0.647		10/15/2014
44	239437		Rusc2	0.215	R2212	G1	222	N		4	43415935	S414A	T	G	missense		Het	probably damaging	1.000	0.102	phenotype	10/15/2014
45	239469		Serpina3j	0.059	R2212	G1	225	N		12	104314726	D53N	G	A	missense		Het	probably damaging	0.989			10/15/2014
46	239444		Sez6l	0.000	R2212	G1	206	N		5	112475361	L108P	A	G	missense		Het	possibly damaging	0.764	0.179	phenotype	10/15/2014
47	239440		Slc1a7	0.092	R2212	G1	225	N		4	108010994	E497G	A	G	missense		Het	probably benign	0.023	0.076		10/15/2014
48	239438		Spag8	0.070	R2212	G1	225	N		4	43651606	S423C	T	A	missense		Het	probably damaging	1.000	0.178	phenotype	10/15/2014
49	239473		Spata13	0.000	R2212	G1	107	N		14	60706723	T522A	A	G	missense		Het	probably benign	0.001	0.090	phenotype	10/15/2014
50	239476		Spryd3	0.000	R2212	G1	224	N		15	102130276		A	G	critical splice donor site	2 bp	Het	probably null				10/15/2014
51	239488		Sry	0.318	R2212	G1	222	N		Y	2663339	N107I	T	A	missense		Het	probably damaging	0.988		phenotype	10/15/2014
52	239467		St6galnac1	0.059	R2212	G1	225	N		11	116765856	W486R	A	G	missense		Het	probably damaging	1.000	0.190	phenotype	10/15/2014
53	239461		Syt1	1.000	R2212	G1	225	N		10	108504414	P348T	G	T	missense		Het	possibly damaging	0.892		phenotype	10/15/2014
54	239451		Taok2	0.000	R2212	G1	225	N		7	126870858	I933V	T	C	missense		Het	possibly damaging	0.785	0.064	phenotype	10/15/2014
55	239458		Tex9	0.074	R2212	G1	225	N		9	72477758	Q265H	C	A	missense		Het	possibly damaging	0.890	0.179		10/15/2014
56	239428		Tmem63a	0.110	R2212	G1	225	N		1	180963114	D446N	G	A	missense		Het	possibly damaging	0.483	0.625		10/15/2014
57	239434		Trim59	0.074	R2212	G1	225	N		3	69037543	T155A	T	C	missense		Het	probably benign	0.307			10/15/2014
58	239431		Trim69	0.077	R2212	G1	225	N		2	122178644	V395A	T	C	missense		Het	probably benign	0.049	0.315	phenotype	10/15/2014
59	239439		Tusc1	0.000	R2212	G1	160	N		4	93334936	R162L	C	A	missense		Het	probably damaging	0.992	0.364	phenotype	10/15/2014
60	239480		Ubash3a	0.000	R2212	G1	135	N		17	31218034	Q208H	A	T	missense		Het	probably damaging	1.000		phenotype	10/15/2014
61	239445		Ubn2	0.781	R2212	G1	225	N		6	38498739	T1211A	A	G	missense		Het	probably benign	0.032	0.058		10/15/2014
62	239479		Vmn2r110	0.208	R2212	G1	225	N		17	20573947		A	T	unclassified	2749 bp	Het	probably null				10/15/2014
63	239447		Vrk3	0.000	R2212	G1	225	N		7	44775442	T427M	C	T	missense		Het	probably benign	0.001	0.090	phenotype	10/15/2014
64	239442		Zfyve28	0.000	R2212	G1	225	N		5	34199684	M723I	C	T	missense		Het	probably benign	0.017	0.090		10/15/2014
65	239433		Zmynd8	1.000	R2212	G1	225	N		2	165815451	M533K	A	T	missense		Het	probably damaging	0.997	0.106	phenotype	10/15/2014
[records 1 to 65 of 65]