• Beutler Lab
  APN
• Strains @ MMRRC
• Display Strains By
  • Institution
  • Phenotype
  • Author
  • Chromosome
  • Inheritance
  • Multifield Search
• Search Mutagenetix
  
  
• Staff Login
• Download

Incidental Mutations

20 incidental mutations are currently displayed, and affect 20 genes.

2 are Possibly Damaging.

9 are Probably Damaging.

6 are Probably Benign.

3 are Probably Null.

0 create premature stop codons.

0 are critical splice junction mutations.

---

Mutations in Coding Regions/Splice Sites Identified by Next-Gen Sequencing

[records 1 to 20 of 20] 10 25 50 100 500 1000 per page Full List
	ID	Source UTSW APN	Gene	E-score	Stock #	Gen G0 G0' G1 G2 G3 G3R F1 F2 F3 C0 C1 C2 C3 D1 HES IPS A3	Quality -	Vld Y N ?	Strain	Chr 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 X Y	Position	Mutation A R N D C E Q G H I L K M F P S T W Y V * A R N D C E Q G H I L K M F P S T W Y V *	Ref A C G T -	Var A C G T -	Type makesense missense nonsense start codon destroyed start gained synonymous splice acceptor site splice donor site critical splice acceptor site critical splice donor site splice site large deletion large insertion rearrangement small deletion small insertion exon frame shift intragenic intron utr 3 prime utr 5 prime unclassified	Exon Dist	Zygosity Homo Het Hemi Null	Predicted Effect unknown probably benign probably null possibly damaging probably damaging noncoding transcript silent not run no transcript	PPH Score -	Meta Score	MGI Phenotype available none listed	Posted
1	257428		0610009O20Rik	0.307	R3005	G1	225	N		18	38259959	N405K	T	A	missense		Het	possibly damaging	0.919			01/11/2015
2	257417		4931406P16Rik	0.000	R3005	G1	225	N		7	34284784	E138G	T	C	missense		Het	probably damaging	1.000			01/11/2015
3	257420		Cep162	0.126	R3005	G1	225	N		9	87232060	V320L	C	A	missense		Het	probably benign	0.001			01/11/2015
4	257411		Cnga1	0.372	R3005	G1	225	N		5	72605107	I355F	T	A	missense		Het	probably damaging	1.000		phenotype	01/11/2015
5	257424		Csnk1e	0.000	R3005	G1	225	N		15	79438805	I15V	T	C	missense		Het	probably benign	0.421		phenotype	01/11/2015
6	257408		Exosc8	1.000	R3005	G1	225	N		3	54732147		T	C	synonymous		Het	probably null			phenotype	01/11/2015
7	257409		Gstm3	0.071	R3005	G1	225	N		3	107967607	Q110K	G	T	missense		Het	probably benign	0.029			01/11/2015
8	257421		Hace1	0.355	R3005	G1	225	N		10	45648863	G242R	G	A	missense		Het	probably damaging	0.964		phenotype	01/11/2015
9	257406		Lcn6	0.086	R3005	G1	213	N		2	25677249		T	A	intron	28 bp	Het	probably null			phenotype	01/11/2015
10	257427		Msh6	1.000	R3005	G1	225	N		17	87988285	E1088G	A	G	missense		Het	probably benign	0.342		phenotype	01/11/2015
11	257415		Nlrp4c	0.060	R3005	G1	225	N		7	6065525	V142M	G	A	missense		Het	probably benign	0.285			01/11/2015
12	257425		Nup50	1.000	R3005	G1	225	N		15	84929460		G	A	splice site	5 bp	Het	probably null			phenotype	01/11/2015
13	257419		Olfr577	0.160	R3005	G1	225	N		7	102973258	V245I	C	T	missense		Het	possibly damaging	0.559		phenotype	01/11/2015
14	257405		Ppp2r5a	0.373	R3005	G1	225	N		1	191358976	F218Y	A	T	missense		Het	probably damaging	0.996		phenotype	01/11/2015
15	257418		Ptov1	0.242	R3005	G1	225	N		7	44864462	N52S	T	C	missense		Het	probably damaging	0.990		phenotype	01/11/2015
16	257407		Rif1	1.000	R3005	G1	225	N		2	52082764	A303T	G	A	missense		Het	probably damaging	1.000		phenotype	01/11/2015
17	257410		Ror1	1.000	R3005	G1	225	N		4	100441764	V778E	T	A	missense		Het	probably damaging	0.989		phenotype	01/11/2015
18	257414		Tcaf3	0.048	R3005	G1	225	N		6	42594044	L258H	A	T	missense		Het	probably damaging	1.000			01/11/2015
19	257422		Utp20	0.962	R3005	G1	225	N		10	88777455	K1321N	C	A	missense		Het	probably damaging	0.970		phenotype	01/11/2015
20	257416		Vmn2r54	0.113	R3005	G1	225	N		7	12615294	Q787L	T	A	missense		Het	probably benign	0.281			01/11/2015
[records 1 to 20 of 20]