Home
Phenotypic Mutations
Incidental Mutations
Engineered Mutations
Candidate Explorer
Protocols
Mutation Statistics
About
Contact
Links
Request Mice
Beutler Lab
APN
Strains @ MMRRC
Search Phenotypes
NEW
Candidate Explorer
Staff Login
Download
Incidental Mutations
42
incidental mutations are currently displayed, and affect
41
genes.
7
are Possibly Damaging.
10
are Probably Damaging.
22
are Probably Benign.
2
are Probably Null.
1
create premature stop codons.
1
are critical splice junction mutations.
Mutations in Coding Regions/Splice Sites Identified by Next-Gen Sequencing
[records 1 to 42 of 42]
10
25
50
100
500
1000
per page
Full List
ID
Source
UTSW
APN
Gene
E-score
Stock #
Gen
G0
G0'
G1
G2
G3
G3R
F1
F2
F3
C0
C1
C2
C3
D1
HES
IPS
A3
ABI
Quality
-
Vld
Y
N
?
Strain
Chr
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
X
Y
Position
Mutation
A
R
N
D
C
E
Q
G
H
I
L
K
M
F
P
S
T
W
Y
V
*
A
R
N
D
C
E
Q
G
H
I
L
K
M
F
P
S
T
W
Y
V
*
Ref
A
C
G
T
-
Var
A
C
G
T
-
Type
makesense
missense
nonsense
start codon destroyed
start gained
synonymous
splice acceptor site
splice donor site
critical splice acceptor site
critical splice donor site
splice site
large deletion
large insertion
rearrangement
small deletion
small insertion
exon
frame shift
intragenic
intron
utr 3 prime
utr 5 prime
unclassified
Exon Dist
Zygosity
Homo
Het
Hemi
Null
Predicted Effect
unknown
probably benign
probably null
possibly damaging
probably damaging
noncoding transcript
silent
not run
no transcript
PPH Score
-
Meta Score
MGI Phenotype
available
none listed
Posted
1
268476
Abcc9
0.135
R3617
G1
225
Y
6
142679289
V460A
A
G
missense
Het
probably damaging
0.970
0.135
phenotype
02/19/2015
2
268474
Aplf
0.104
R3617
G1
225
Y
6
87671883
I25V
T
C
missense
Het
possibly damaging
0.854
0.066
phenotype
02/19/2015
3
268482
Ascc3
0.960
R3617
G1
225
Y
10
50618185
T239A
A
G
missense
Het
probably benign
0.002
0.059
phenotype
02/19/2015
4
268458
Bahd1
0.000
R3617
G1
205
Y
2
118922523
R757H
G
A
missense
Het
probably damaging
1.000
0.816
phenotype
02/19/2015
5
473062
Cbfa2t2
0.729
R3617
G1
225
N
2
154436984
A
T
intron
Het
probably benign
phenotype
04/14/2017
6
268479
Cdkn1c
0.703
R3617
G1
225
Y
7
143459794
C
T
critical splice donor site
Het
probably benign
0.087
phenotype
02/19/2015
7
268477
Cfap46
0.000
R3617
G1
225
Y
7
139639599
S1317P
A
G
missense
Het
probably benign
0.056
0.090
02/19/2015
8
268464
Cntln
0.248
R3617
G1
225
Y
4
85004977
Q560*
C
T
nonsense
Het
probably null
0.976
02/19/2015
9
268456
Cntn2
0.245
R3617
G1
225
Y
1
132528623
A161G
G
C
missense
Het
probably benign
0.161
0.085
phenotype
02/19/2015
10
268481
Crybg1
1.000
R3617
G1
225
Y
10
43956786
I1991T
A
G
missense
Het
possibly damaging
0.821
0.273
02/19/2015
11
268471
Cttnbp2
0.000
R3617
G1
225
Y
6
18414190
E952G
T
C
missense
Het
probably damaging
1.000
0.337
phenotype
02/19/2015
12
268460
Dhx36
1.000
R3617
G1
225
Y
3
62472007
T887A
T
C
missense
Het
possibly damaging
0.956
0.565
phenotype
02/19/2015
13
268461
Dhx36
1.000
R3617
G1
225
Y
3
62487060
F512L
A
G
missense
Het
probably benign
0.013
0.149
phenotype
02/19/2015
14
341764
Fthl17f
0.117
R3617
G1
56.1
Y
X
9063623
T153A
A
G
missense
Het
probably benign
0.327
0.090
09/23/2015
15
268485
Gad1-ps
0.241
R3617
G1
225
Y
10
99445398
T
A
exon
Het
noncoding transcript
0.359
02/19/2015
16
268463
Gba2
0.000
R3617
G1
225
Y
4
43573803
R163H
C
T
missense
Het
probably damaging
1.000
0.249
phenotype
02/19/2015
17
341763
Gm10717
0.786
R3617
G1
38
Y
9
3025532
Y39C
A
G
missense
Het
probably benign
0.000
0.090
09/23/2015
18
341762
Gm17019
0.074
R3617
G1
79
Y
5
15031067
M120K
A
T
missense
Het
possibly damaging
0.879
0.703
09/23/2015
19
268454
Gm8251
0.087
R3617
G1
225
Y
1
44060954
D328G
T
C
missense
Het
probably benign
0.000
0.090
02/19/2015
20
268459
Helz2
0.000
R3617
G1
225
Y
2
181233061
R1880H
C
T
missense
Het
probably damaging
1.000
0.167
phenotype
02/19/2015
21
268457
Ifi204
0.200
R3617
G1
225
Y
1
173755717
I312V
T
C
missense
Het
possibly damaging
0.511
0.179
02/19/2015
22
268465
Kncn
0.111
R3617
G1
225
Y
4
115885892
F55L
T
C
missense
Het
probably benign
0.000
0.090
02/19/2015
23
268478
Kndc1
0.000
R3617
G1
225
Y
7
139902060
G
A
splice site
Het
probably benign
0.090
phenotype
02/19/2015
24
268473
Nat8f3
0.044
R3617
G1
128
N
6
85761688
A31S
C
A
missense
Het
probably benign
0.050
02/19/2015
25
268462
Ndst4
0.079
R3617
G1
225
Y
3
125438133
I117T
T
C
missense
Het
probably benign
0.001
0.169
phenotype
02/19/2015
26
268475
Ndufa9
1.000
R3617
G1
223
Y
6
126849108
G
T
unclassified
Het
probably benign
0.105
phenotype
02/19/2015
27
268467
Nupl2
0.891
R3617
G1
225
Y
5
24182327
S372P
T
C
missense
Het
probably benign
0.036
0.130
02/19/2015
28
268492
Pde6a
0.000
R3617
G1
225
Y
18
61231503
A
G
splice site
Het
probably benign
0.090
phenotype
02/19/2015
29
268487
Pigw
0.132
R3617
G1
225
Y
11
84878307
I65M
T
C
missense
Het
probably damaging
0.980
0.173
phenotype
02/19/2015
30
473064
Pip
0.055
R3617
G1
225
N
6
41851937
T139A
A
G
missense
Het
probably benign
0.230
phenotype
04/14/2017
31
268486
Rel
0.000
R3617
G1
225
Y
11
23745780
D202E
A
T
missense
Het
probably damaging
0.999
0.104
phenotype
02/19/2015
32
268491
Rhot2
0.104
R3617
G1
225
Y
17
25840981
A
G
unclassified
Het
probably benign
phenotype
02/19/2015
33
268484
Sh3rf3
0.215
R3617
G1
225
Y
10
59086863
R587Q
G
A
missense
Het
possibly damaging
0.834
0.106
02/19/2015
34
268483
Sim1
1.000
R3617
G1
225
Y
10
50909528
M231K
T
A
missense
Het
probably damaging
1.000
0.671
phenotype
02/19/2015
35
268470
Slc12a9
0.362
R3617
G1
225
Y
5
137332497
T47M
G
A
missense
Het
probably damaging
1.000
0.647
02/19/2015
36
268468
Slc4a4
1.000
R3617
G1
225
Y
5
89234804
D1036G
A
G
missense
Het
probably benign
0.002
0.093
phenotype
02/19/2015
37
268472
Tas2r143
0.050
R3617
G1
225
Y
6
42401063
I276F
A
T
missense
Het
probably benign
0.198
0.090
02/19/2015
38
268469
Tgfbr3
1.000
R3617
G1
225
Y
5
107140619
F392Y
A
T
missense
Het
possibly damaging
0.653
0.179
phenotype
02/19/2015
39
268480
Tmem266
0.074
R3617
G1
225
Y
9
55400634
V148A
T
C
missense
Het
probably damaging
0.990
0.150
02/19/2015
40
268466
Ubiad1
1.000
R3617
G1
225
Y
4
148436360
I269T
A
G
missense
Het
probably benign
0.011
0.090
phenotype
02/19/2015
41
268455
Vwc2l
0.000
R3617
G1
225
Y
1
70728882
A
G
splice site
4 bp
Het
probably null
0.107
02/19/2015
42
473063
Zbtb49
0.089
R3617
G1
225
N
5
38200631
G
A
unclassified
Het
probably benign
04/14/2017
[records 1 to 42 of 42]