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Incidental Mutations

85 incidental mutations are currently displayed, and affect 85 genes.

12 are Possibly Damaging.

27 are Probably Damaging.

31 are Probably Benign.

12 are Probably Null.

5 create premature stop codons.

3 are critical splice junction mutations.

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Mutations in Coding Regions/Splice Sites Identified by Next-Gen Sequencing

[records 1 to 85 of 85] 10 25 50 100 500 1000 per page Full List
	ID	Source UTSW APN	Gene	E-score	Stock #	Gen G0 G0' G1 G2 G3 G3R F1 F2 F3 C0 C1 C2 C3 D1 HES IPS A3	Quality -	Vld Y N ?	Strain	Chr 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 X Y	Position	Mutation A R N D C E Q G H I L K M F P S T W Y V * A R N D C E Q G H I L K M F P S T W Y V *	Ref A C G T -	Var A C G T -	Type makesense missense nonsense start codon destroyed start gained synonymous splice acceptor site splice donor site critical splice acceptor site critical splice donor site splice site large deletion large insertion rearrangement small deletion small insertion exon frame shift intragenic intron utr 3 prime utr 5 prime unclassified	Exon Dist	Zygosity Homo Het Hemi Null	Predicted Effect unknown probably benign probably null possibly damaging probably damaging noncoding transcript silent not run no transcript	PPH Score -	Meta Score	MGI Phenotype available none listed	Posted
1	344001		Akap9	0.406	R4585	G1	187	N		5	3976151	S1269P	T	C	missense		Het	probably benign	0.005		phenotype	09/24/2015
2	343998		Akr7a5	0.277	R4585	G1	99.1	Y		4	139310927	R58L	G	T	missense		Het	probably benign	0.091	0.172	phenotype	09/24/2015
3	344016		Art2a-ps	0.058	R4585	G1	225	Y		7	101554749	L194*	A	T	nonsense		Het	probably null		0.976	phenotype	09/24/2015
4	343999		Aurkaip1	1.000	R4585	G1	225	Y		4	155832634	A113D	C	A	missense		Het	possibly damaging	0.553	0.118		09/24/2015
5	344028		Bsn	0.342	R4585	G1	159	Y		9	108110463		T	C	unclassified		Het	probably benign		0.087	phenotype	09/24/2015
6	344045		Ccdc175	0.067	R4585	G1	225	Y		12	72175179	D123A	T	G	missense		Het	possibly damaging	0.651	0.112		09/24/2015
7	344023		Ccdc7b	0.054	R4585	G1	225	Y		8	129110920	T131A	A	G	missense		Het	probably benign	0.061	0.090		09/24/2015
8	343976		Ccnt2	1.000	R4585	G1	225	Y		1	127803029	S548P	T	C	missense		Het	probably damaging	0.994	0.145	phenotype	09/24/2015
9	344024		Cep126	0.000	R4585	G1	225	Y		9	8103337	Q224R	T	C	missense		Het	probably damaging	0.994	0.089		09/24/2015
10	344013		Cic	0.933	R4585	G1	225	Y		7	25272778	I645L	A	T	missense		Het	probably benign	0.326	0.090	phenotype	09/24/2015
11	344022		Cngb1	1.000	R4585	G1	225	Y		8	95297128		C	T	critical splice acceptor site		Het	probably null		0.921	phenotype	09/24/2015
12	344031		Col13a1	0.000	R4585	G1	186	Y		10	61887245		T	C	splice site	4 bp	Het	probably null		0.976	phenotype	09/24/2015
13	344004		Corin	0.344	R4585	G1	225	Y		5	72329699	V706D	A	T	missense		Het	probably damaging	1.000	0.219	phenotype	09/24/2015
14	344057		Crebrf	0.545	R4585	G1	225	Y		17	26762255	K535R	A	G	missense		Het	probably damaging	0.996	0.167	phenotype	09/24/2015
15	344017		Cuzd1	0.121	R4585	G1	225	Y		7	131314800	P310L	G	A	missense		Het	probably damaging	1.000	0.587	phenotype	09/24/2015
16	344026		Cxcr5	0.076	R4585	G1	225	Y		9	44514145	I72F	T	A	missense		Het	probably benign	0.397	0.090	phenotype	09/24/2015
17	343993		Dapp1	0.121	R4585	G1	225	Y		3	137939171	Q148R	T	C	missense		Het	probably benign	0.050	0.090	phenotype	09/24/2015
18	343982		Dcaf17	0.447	R4585	G1	225	Y		2	71088580	S499R	T	A	missense		Het	probably benign	0.004	0.090	phenotype	09/24/2015
19	344019		Defb3	0.000	R4585	G1	225	Y		8	19295156	I43F	A	T	missense		Het	possibly damaging	0.872	0.179	phenotype	09/24/2015
20	344018		Dlgap2	0.000	R4585	G1	225	Y		8	14727999		G	A	critical splice donor site	1 bp	Het	probably null		0.949	phenotype	09/24/2015
21	344058		Dnah8	0.308	R4585	G1	225	Y		17	30751567	D2684G	A	G	missense		Het	probably benign	0.006	0.091	phenotype	09/24/2015
22	343984		Dnajc10	0.266	R4585	G1	225	Y		2	80347778	F710V	T	G	missense		Het	probably damaging	1.000	0.742	phenotype	09/24/2015
23	344006		Ep400	1.000	R4585	G1	225	Y		5	110753859	T464I	G	A	missense		Het	probably damaging	1.000	0.122	phenotype	09/24/2015
24	344059		Epc1	1.000	R4585	G1	225	Y		18	6441157	Q14*	G	A	nonsense		Het	probably null		0.976	phenotype	09/24/2015
25	344038		Eral1	1.000	R4585	G1	225	Y		11	78078304	N123K	A	T	missense		Het	probably damaging	0.999	0.889	phenotype	09/24/2015
26	343973		Ercc5	1.000	R4585	G1	225	Y		1	44158857	V145I	G	A	missense		Het	probably benign	0.360	0.064	phenotype	09/24/2015
27	344003		Evc	0.223	R4585	G1	225	Y		5	37323713	S263P	A	G	missense		Het	probably damaging	0.961	0.104	phenotype	09/24/2015
28	344049		Fancc	0.901	R4585	G1	225	Y		13	63347564	M182K	A	T	missense		Het	probably benign	0.138	0.090	phenotype	09/24/2015
29	344052		Fbxl3	0.167	R4585	G1	225	Y		14	103083090	A355E	G	T	missense		Het	probably damaging	0.994	0.717	phenotype	09/24/2015
30	344021		Glra3	0.000	R4585	G1	225	Y		8	56088993	T257K	C	A	missense		Het	probably damaging	0.997	0.394	phenotype	09/24/2015
31	343996		Gm12789	0.098	R4585	G1	225	Y		4	101989962	Y148C	A	G	missense		Het	possibly damaging	0.503	0.179		09/24/2015
32	343991		Gm14393	0.138	R4585	G1	189	Y		2	175062704		C	A	unclassified		Het	probably benign				09/24/2015
33	343975		Gm19965	0.089	R4585	G1	225	Y		1	116821778	N396K	T	A	missense		Het	probably benign	0.001			09/24/2015
34	344010		Gm27013	0.204	R4585	G1	225	Y		6	130521040		A	T	unclassified		Het	noncoding transcript				09/24/2015
35	344009		Gmcl1	0.456	R4585	G1	225	Y		6	86722623	S141P	A	G	missense		Het	probably damaging	1.000	0.588	phenotype	09/24/2015
36	344054		Gsdmd	0.000	R4585	G1	225	Y		15	75865751		T	A	splice site		Het	probably null		0.976	phenotype	09/24/2015
37	344046		Gtf2a1	1.000	R4585	G1	225	Y		12	91562926	V338I	C	T	missense		Het	possibly damaging	0.658	0.212	phenotype	09/24/2015
38	344041		Hap1	0.558	R4585	G1	225	Y		11	100354724	T138M	G	A	missense		Het	probably benign	0.214	0.090	phenotype	09/24/2015
39	344048		Hist1h2ak	0.415	R4585	G1	225	Y		13	21753712	N39S	T	C	missense		Het	possibly damaging	0.923	0.080	phenotype	09/24/2015
40	344039		Ints2	1.000	R4585	G1	225	Y		11	86249275	R244S	G	T	missense		Het	probably damaging	0.998	0.145	phenotype	09/24/2015
41	344043		Itgb4	1.000	R4585	G1	225	Y		11	115993325	V945A	T	C	missense		Het	probably damaging	0.999	0.511	phenotype	09/24/2015
42	343978		Itih2	0.107	R4585	G1	225	Y		2	10110400	S387N	C	T	missense		Het	probably benign	0.001	0.117	phenotype	09/24/2015
43	344011		Klra2	0.060	R4585	G1	225	Y		6	131230157	D163V	T	A	missense		Het	probably benign	0.114	0.090	phenotype	09/24/2015
44	344027		Lctl	0.125	R4585	G1	225	Y		9	64131600	S324P	T	C	missense		Het	probably damaging	0.998	0.535	phenotype	09/24/2015
45	344055		Lrrc24	0.089	R4585	G1	225	Y		15	76723689	R43L	C	A	missense		Het	probably damaging	1.000	0.689		09/24/2015
46	344008		Mogs	1.000	R4585	G1	225	Y		6	83118638	R812L	G	T	missense		Het	possibly damaging	0.561	0.098	phenotype	09/24/2015
47	344053		Mroh5	0.054	R4585	G1	225	Y		15	73789271	T467S	T	A	missense		Het	probably benign	0.377	0.085		09/24/2015
48	343995		Mtap	1.000	R4585	G1	225	Y		4	89172274	V194I	G	A	missense		Het	probably benign	0.000	0.090	phenotype	09/24/2015
49	344050		Myoz1	0.000	R4585	G1	225	Y		14	20650595	W185R	A	G	missense		Het	probably damaging	0.999	0.969	phenotype	09/24/2015
50	344037		Nufip2	0.953	R4585	G1	190	Y		11	77741728	V690A	T	C	missense		Het	unknown		0.087		09/24/2015
51	344012		Obox1	0.236	R4585	G1	225	Y		7	15556227	N165I	A	T	missense		Het	possibly damaging	0.656	0.179		09/24/2015
52	343985		Olfr1218	0.064	R4585	G1	225	Y		2	89055154	I91L	T	G	missense		Het	possibly damaging	0.775	0.294	phenotype	09/24/2015
53	343980		Olfr3	0.303	R4585	G1	225	Y		2	36812525	C189Y	C	T	missense		Het	probably damaging	0.997	0.703	phenotype	09/24/2015
54	343986		Olfr32	0.077	R4585	G1	225	Y		2	90138214	E308D	T	A	missense		Het	probably benign	0.011	0.090	phenotype	09/24/2015
55	344033		Olfr781	0.091	R4585	G1	225	Y		10	129333273	T131A	A	G	missense		Het	probably benign	0.077	0.090	phenotype	09/24/2015
56	344056		Pabpc6	0.197	R4585	G1	225	Y		17	9669073	L183P	A	G	missense		Het	probably damaging	1.000	0.160		09/24/2015
57	344032		Pcdh15	0.000	R4585	G1	225	Y		10	74624284	R1355W	C	T	missense		Het	probably damaging	1.000	0.880	phenotype	09/24/2015
58	344060		Pcdhgb8	0.165	R4585	G1	225	Y		18	37762360	A161E	C	A	missense		Het	probably benign	0.243	0.090		09/24/2015
59	344000		Pex1	0.590	R4585	G1	225	Y		5	3633885	Y1127C	A	G	missense		Het	probably damaging	1.000	0.566	phenotype	09/24/2015
60	343997		Phc2	0.000	R4585	G1	225	Y		4	128743510	H563L	A	T	missense		Het	probably damaging	0.999	0.918	phenotype	09/24/2015
61	344020		Plekha2	0.000	R4585	G1	225	Y		8	25043669	E291*	C	A	nonsense		Het	probably null		0.976	phenotype	09/24/2015
62	343988		Qser1	0.477	R4585	G1	225	Y		2	104786793	V1225L	C	A	missense		Het	probably benign	0.012	0.090		09/24/2015
63	343990		Ralgapa2	0.346	R4585	G1	225	Y		2	146315024	D1882E	A	T	missense		Het	probably damaging	0.991	0.188	phenotype	09/24/2015
64	344029		Rgs17	0.292	R4585	G1	225	Y		10	5842596	D70G	T	C	missense		Het	probably benign	0.002	0.090	phenotype	09/24/2015
65	343994		Runx1t1	0.826	R4585	G1	225	Y		4	13889864	T598S	A	T	missense		Het	unknown		0.070	phenotype	09/24/2015
66	343981		Scn2a	1.000	R4585	G1	225	Y		2	65743051		T	A	splice site		Het	probably null		0.976	phenotype	09/24/2015
67	343974		Serpinb10	0.000	R4585	G1	225	Y		1	107547049	C314S	T	A	missense		Het	probably benign	0.012	0.090		09/24/2015
68	344061		Setbp1	0.640	R4585	G1	225	Y		18	79086949	S23A	A	C	missense		Het	probably benign	0.002	0.059	phenotype	09/24/2015
69	344034		Sh3pxd2b	0.314	R4585	G1	225	Y		11	32396479	D116G	A	G	missense		Het	possibly damaging	0.843	0.080	phenotype	09/24/2015
70	344042		Slc4a1	1.000	R4585	G1	225	Y		11	102361419		G	T	utr 5 prime		Het	probably benign		0.090	phenotype	09/24/2015
71	344025		Snx19	0.126	R4585	G1	225	Y		9	30440195	L155P	T	C	missense		Het	probably damaging	1.000	0.846	phenotype	09/24/2015
72	343992		Sox2	1.000	R4585	G1	225	Y		3	34651044	N210S	A	G	missense		Het	probably benign	0.019	0.080	phenotype	09/24/2015
73	343979		Spag6	0.070	R4585	G1	225	Y		2	18732147		T	C	critical splice donor site	2 bp	Het	probably null		0.949		09/24/2015
74	344002		Speer4b	0.089	R4585	G1	145	Y		5	27498038	L154Q	A	T	missense		Het	probably null	0.998	0.976		09/24/2015
75	344044		Strn3	1.000	R4585	G1	225	Y		12	51650170	E259D	T	A	missense		Het	probably benign	0.023	0.083		09/24/2015
76	344062		Tenm1	0.281	R4585	G1	222	N		X	42537979	Q1931*	G	A	nonsense		Het	probably null			phenotype	09/24/2015
77	343989		Trp53bp1	0.000	R4585	G1	225	Y		2	121207951	G1469R	C	G	missense		Het	probably damaging	1.000	0.089	phenotype	09/24/2015
78	344047		Ttc8	0.504	R4585	G1	225	Y		12	98982530	Q492K	C	A	missense		Het	probably benign	0.000	0.094	phenotype	09/24/2015
79	343983		Ttn	1.000	R4585	G1	225	Y		2	76968403	H509R	T	C	missense		Het	probably benign	0.001	0.112	phenotype	09/24/2015
80	344030		Utrn	0.000	R4585	G1	225	Y		10	12688306	H1270L	T	A	missense		Het	probably benign	0.014	0.090	phenotype	09/24/2015
81	344007		Vopp1	0.000	R4585	G1	225	Y		6	57754548	P153S	G	A	missense		Het	probably damaging	1.000	0.286		09/24/2015
82	344051		Wdfy4	0.000	R4585	G1	225	Y		14	33087955	I1770F	T	A	missense		Het	possibly damaging	0.891	0.179		09/24/2015
83	344014		Zfp14	0.000	R4585	G1	225	Y		7	30038916	Q215K	G	T	missense		Het	probably damaging	0.993	0.145		09/24/2015
84	344015		Zfp473	0.100	R4585	G1	225	Y		7	44732952	Y651*	A	T	nonsense		Het	probably null		0.976	phenotype	09/24/2015
85	344036		Zfp735	0.073	R4585	G1	225	Y		11	73689724	E16D	G	T	missense		Het	possibly damaging	0.511	0.179		09/24/2015
[records 1 to 85 of 85]