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Incidental Mutations

61 incidental mutations are currently displayed, and affect 61 genes.

5 are Possibly Damaging.

26 are Probably Damaging.

19 are Probably Benign.

7 are Probably Null.

2 create premature stop codons.

2 are critical splice junction mutations.

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Mutations in Coding Regions/Splice Sites Identified by Next-Gen Sequencing

[records 1 to 61 of 61] 10 25 50 100 500 1000 per page Full List
	ID	Source UTSW APN	Gene	E-score	Stock #	Gen G0 G0' G1 G2 G3 G3R F1 F2 F3 C0 C1 C2 C3 D1 HES IPS A3	Quality -	Vld Y N ?	Strain	Chr 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 X Y	Position	Mutation A R N D C E Q G H I L K M F P S T W Y V * A R N D C E Q G H I L K M F P S T W Y V *	Ref A C G T -	Var A C G T -	Type makesense missense nonsense start codon destroyed start gained synonymous splice acceptor site splice donor site critical splice acceptor site critical splice donor site splice site large deletion large insertion rearrangement small deletion small insertion exon frame shift intragenic intron utr 3 prime utr 5 prime unclassified	Exon Dist	Zygosity Homo Het Hemi Null	Predicted Effect unknown probably benign probably null possibly damaging probably damaging noncoding transcript silent not run no transcript	PPH Score -	Meta Score	MGI Phenotype available none listed	Posted
1	351061		2010111I01Rik	0.152	R4616	G1	225	Y		13	63298751	E123K	G	A	missense		Het	probably damaging	1.000	0.403	phenotype	10/08/2015
2	351040		4931417E11Rik	0.137	R4616	G1	225	Y		6	73469269	V99A	A	G	missense		Het	probably benign	0.021	0.090		10/08/2015
3	351062		Acod1	0.000	R4616	G1	225	Y		14	103055345	T435M	C	T	missense		Het	probably benign	0.097	0.090	phenotype	10/08/2015
4	351069		Adgrf5	0.000	R4616	G1	225	Y		17	43452440	F1078L	T	C	missense		Het	probably benign	0.376	0.189	phenotype	10/08/2015
5	351031		Adh6a	0.092	R4616	G1	225	Y		3	138324947	N110I	A	T	missense		Het	probably damaging	1.000	0.872		10/08/2015
6	351043		Aldh16a1	0.000	R4616	G1	225	Y		7	45148788		T	C	intron		Het	probably benign		0.090	phenotype	10/08/2015
7	351045		Arhgef17	0.000	R4616	G1	225	Y		7	100882485	F1302S	A	G	missense		Het	probably damaging	0.999	0.933		10/08/2015
8	351051		Bcl2a1a	0.152	R4616	G1	225	Y		9	88957453	R135W	C	T	missense		Het	probably damaging	0.999	0.647	phenotype	10/08/2015
9	351023		Bpifa6	0.066	R4616	G1	225	Y		2	153982988	S28P	T	C	missense		Het	possibly damaging	0.473	0.179		10/08/2015
10	351063		C9	0.000	R4616	G1	225	Y		15	6491463	D51G	A	G	missense		Het	probably damaging	0.991	0.647	phenotype	10/08/2015
11	351068		Cfb	0.000	R4616	G1	225	Y		17	34859068	H962L	T	A	missense		Het	probably benign	0.287	0.090	phenotype	10/08/2015
12	351038		Chn2	0.190	R4616	G1	225	Y		6	54290403	M292I	G	A	missense		Het	probably damaging	0.997	0.110	phenotype	10/08/2015
13	351066		Clec16a	0.181	R4616	G1	225	Y		16	10644883		T	A	critical splice donor site	2 bp	Het	probably null		0.950	phenotype	10/08/2015
14	351049		Cyp1a1	0.081	R4616	G1	225	Y		9	57701756	S307P	T	C	missense		Het	probably benign	0.091	0.127	phenotype	10/08/2015
15	351072		Dsg3	0.420	R4616	G1	225	Y		18	20531559	V538A	T	C	missense		Het	probably benign	0.000	0.090	phenotype	10/08/2015
16	351053		Erbb3	1.000	R4616	G1	225	Y		10	128572770	Q815*	G	A	nonsense		Het	probably null		0.975	phenotype	10/08/2015
17	351048		Fam90a1a	0.066	R4616	G1	216	Y		8	21963846	Q406K	C	A	missense		Het	possibly damaging	0.483	0.179		10/08/2015
18	351033		Frmd3	0.399	R4616	G1	225	Y		4	74187872	V585A	T	C	missense		Het	probably benign	0.149	0.102	phenotype	10/08/2015
19	351078		Gm7102	0.160	R4616	G1	225	Y		19	61175926	G24R	C	T	missense		Het	unknown		0.109		10/08/2015
20	351020		Gm8214	0.187	R4616	G1	225	Y		1	183681897		T	C	exon		Het	noncoding transcript		0.087		10/08/2015
21	351060		Gpld1	0.000	R4616	G1	225	Y		13	24984816	G771D	G	A	missense		Het	probably damaging	1.000	0.266	phenotype	10/08/2015
22	351064		Gpr20	0.000	R4616	G1	225	Y		15	73695736	N268S	T	C	missense		Het	probably benign	0.000	0.090		10/08/2015
23	351027		Gria2	0.528	R4616	G1	225	Y		3	80706897	I612N	A	T	missense		Het	probably damaging	0.998	0.874	phenotype	10/08/2015
24	351076		Ifit1bl1	0.000	R4616	G1	135	Y		19	34594610	E149G	T	C	missense		Het	probably damaging	1.000	0.832		10/08/2015
25	351058		Ighv1-82	0.286	R4616	G1	225	Y		12	115952660	T77A	T	C	missense		Het	probably benign	0.057	0.090		10/08/2015
26	351057		Ighv2-9	0.110	R4616	G1	225	Y		12	113879219	T76K	G	T	missense		Het	probably damaging	0.991	0.647		10/08/2015
27	470265		Igkv6-13	0.103	R4616	G1	225	N		6	70458035	M1K	A	T	start codon destroyed		Het	probably null	0.948			03/08/2017
28	351039		Igkv8-21	0.161	R4616	G1	225	Y		6	70315157	S34T	A	T	missense		Het	probably benign	0.051	0.090		10/08/2015
29	386331		Itpr1	0.874	R4616	G1	225	Y		6	108481223	N1985D	A	G	missense		Het	probably damaging	0.997	0.489	phenotype	05/11/2016
30	351071		Lama3	1.000	R4616	G1	225	Y		18	12504397		T	C	critical splice donor site	2 bp	Het	probably null		0.948	phenotype	10/08/2015
31	351019		Lamc2	0.720	R4616	G1	225	Y		1	153166169	Y73C	T	C	missense		Het	probably damaging	1.000	0.693	phenotype	10/08/2015
32	386333		Maff	0.000	R4616	G1	54	Y		15	79357698	D105G	A	G	missense		Het	probably damaging	0.998	0.949	phenotype	05/11/2016
33	351070		Mep1a	0.000	R4616	G1	225	Y		17	43486241	V312M	C	T	missense		Het	possibly damaging	0.807	0.200	phenotype	10/08/2015
34	351054		Mfap4	0.000	R4616	G1	174	Y		11	61485509		C	A	unclassified		Het	probably benign		0.090	phenotype	10/08/2015
35	351025		Mrgbp	0.542	R4616	G1	225	Y		2	180585314		A	T	synonymous		Het	silent				10/08/2015
36	386332		Mtmr4	0.310	R4616	G1	225	Y		11	87610935	L548S	T	C	missense		Het	probably damaging	0.992	0.063		05/11/2016
37	351073		Myo7b	0.000	R4616	G1	225	Y		18	32003487		T	C	splice site	4 bp	Het	probably null		0.976	phenotype	10/08/2015
38	351050		Myo9a	0.000	R4616	G1	225	Y		9	59821649	I596T	T	C	missense		Het	probably damaging	1.000	0.792	phenotype	10/08/2015
39	351037		Olfr38	0.101	R4616	G1	225	Y		6	42762418	R122L	G	T	missense		Het	probably benign	0.066	0.220	phenotype	10/08/2015
40	351046		Olfr594	0.072	R4616	G1	225	Y		7	103220422	R235*	C	T	nonsense		Het	probably null		0.976	phenotype	10/08/2015
41	351075		Pcsk5	1.000	R4616	G1	225	Y		19	17560750	Q904H	T	G	missense		Het	probably benign	0.001	0.162	phenotype	10/08/2015
42	351041		Pdzrn3	0.711	R4616	G1	225	Y		6	101152009	H565Q	G	T	missense		Het	probably damaging	0.994	0.074	phenotype	10/08/2015
43	351047		Phkg2	0.543	R4616	G1	225	Y		7	127577620	R61W	C	T	missense		Het	probably damaging	0.999	0.282	phenotype	10/08/2015
44	351077		Pkd2l1	0.107	R4616	G1	225	Y		19	44154134	A490S	C	A	missense		Het	probably damaging	0.991	0.421	phenotype	10/08/2015
45	351034		Pomgnt1	0.000	R4616	G1	225	Y		4	116154890	I337N	T	A	missense		Het	probably damaging	1.000	0.929	phenotype	10/08/2015
46	351055		Psmd3	0.948	R4616	G1	192	Y		11	98682926	V66A	T	C	missense		Het	probably benign	0.003	0.062	phenotype	10/08/2015
47	351032		Ptger3	0.082	R4616	G1	213	Y		3	157567294	S93P	T	C	missense		Het	probably damaging	0.997	0.732	phenotype	10/08/2015
48	351074		Rbm27	0.000	R4616	G1	225	Y		18	42301775	D301E	T	A	missense		Het	probably damaging	0.964	0.481		10/08/2015
49	351052		Rdh16	0.000	R4616	G1	225	Y		10	127801513		A	T	splice site	3 bp	Het	probably null		0.976		10/08/2015
50	351067		Slc35a5	0.170	R4616	G1	225	Y		16	45144292	F193I	A	T	missense		Het	probably benign	0.124	0.071	phenotype	10/08/2015
51	351036		Slc4a4	1.000	R4616	G1	225	Y		5	89038561	K167R	A	G	missense		Het	probably damaging	0.999	0.089	phenotype	10/08/2015
52	351029		Sort1	0.827	R4616	G1	225	Y		3	108355541	T772S	A	T	missense		Het	possibly damaging	0.659	0.179	phenotype	10/08/2015
53	351022		Sptbn5	0.278	R4616	G1	203	Y		2	120048757		T	A	exon		Het	noncoding transcript				10/08/2015
54	351044		Stard5	0.000	R4616	G1	225	Y		7	83633281		G	T	intron		Het	probably benign			phenotype	10/08/2015
55	351065		Tbc1d22a	0.000	R4616	G1	225	Y		15	86235685	T61A	A	G	missense		Het	probably damaging	1.000	0.185		10/08/2015
56	351024		Tox2	0.000	R4616	G1	225	N		2	163320647	L479P	T	C	missense		Het	probably damaging	1.000	0.426		10/08/2015
57	351030		Usp53	0.161	R4616	G1	225	Y		3	122959120	M80K	A	T	missense		Het	probably damaging	0.996	0.222	phenotype	10/08/2015
58	351059		Vmn1r209	0.138	R4616	G1	225	Y		13	22805965	L185Q	A	T	missense		Het	probably damaging	0.998	0.647		10/08/2015
59	351042		Vmn2r59	0.075	R4616	G1	225	Y		7	42012438	I651T	A	G	missense		Het	probably benign	0.000	0.090		10/08/2015
60	351079		Vsig1	0.063	R4616	G1	222	Y		X	140926386	A95S	G	T	missense		Het	probably benign	0.011	0.090	phenotype	10/08/2015
61	351026		Zfhx4	0.786	R4616	G1	225	Y		3	5413067	S3556P	T	C	missense		Het	possibly damaging	0.659	0.060		10/08/2015
[records 1 to 61 of 61]