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Incidental Mutations

59 incidental mutations are currently displayed, and affect 58 genes.

7 are Possibly Damaging.

20 are Probably Damaging.

25 are Probably Benign.

5 are Probably Null.

2 create premature stop codons.

1 are critical splice junction mutations.

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Mutations in Coding Regions/Splice Sites Identified by Next-Gen Sequencing

[records 1 to 59 of 59] 10 25 50 100 500 1000 per page Full List
	ID	Source UTSW APN	Gene	E-score	Stock #	Gen G0 G0' G1 G2 G3 G3R F1 F2 F3 C0 C1 C2 C3 D1 HES IPS A3	Quality -	Vld Y N ?	Strain	Chr 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 X Y	Position	Mutation A R N D C E Q G H I L K M F P S T W Y V * A R N D C E Q G H I L K M F P S T W Y V *	Ref A C G T -	Var A C G T -	Type makesense missense nonsense start codon destroyed start gained synonymous splice acceptor site splice donor site critical splice acceptor site critical splice donor site splice site large deletion large insertion rearrangement small deletion small insertion exon frame shift intragenic intron utr 3 prime utr 5 prime unclassified	Exon Dist	Zygosity Homo Het Hemi Null	Predicted Effect unknown probably benign probably null possibly damaging probably damaging noncoding transcript silent not run no transcript	PPH Score -	Meta Score	MGI Phenotype available none listed	Posted
1	394621		Ahnak	0.280	R5050	G1	145	Y		19	9012458		A	G	intron		Het	probably benign		0.125	phenotype	06/15/2016
2	394610		Ap3m1	0.136	R5050	G1	225	Y		14	21044775	I108T	A	G	missense		Het	probably benign	0.002	0.062	phenotype	06/15/2016
3	394590		Apobec1	0.000	R5050	G1	225	Y		6	122591102	M1V	T	C	start codon destroyed		Het	probably null	0.182	0.955	phenotype	06/15/2016
4	394579		Aqr	1.000	R5050	G1	225	Y		2	114112609	L1161*	A	T	nonsense		Het	probably null		0.976	phenotype	06/15/2016
5	394580		Aqr	1.000	R5050	G1	225	Y		2	114170025		A	T	critical splice donor site	2 bp	Het	probably null		0.949	phenotype	06/15/2016
6	394618		Arhgef37	0.153	R5050	G1	191	Y		18	61504331	I420T	A	G	missense		Het	probably benign	0.430	0.405		06/15/2016
7	394601		Cacna1g	0.660	R5050	G1	161	Y		11	94459715	E435K	C	T	missense		Het	probably damaging	1.000	0.414	phenotype	06/15/2016
8	394611		Card6	0.000	R5050	G1	215	Y		15	5100376	H513N	G	T	missense		Het	probably benign	0.003	0.090	phenotype	06/15/2016
9	394587		Ccdc158	0.165	R5050	G1	225	Y		5	92666879	F29L	A	C	missense		Het	probably benign	0.015	0.066		06/15/2016
10	394617		Ccr6	0.000	R5050	G1	225	Y		17	8256104	L47S	T	C	missense		Het	probably damaging	0.998	0.250	phenotype	06/15/2016
11	394574		Cdc42bpa	0.591	R5050	G1	225	Y		1	180072453	Y444*	T	A	nonsense		Het	probably null		0.976	phenotype	06/15/2016
12	394585		Cdh17	0.108	R5050	G1	225	Y		4	11784654	Y270C	A	G	missense		Het	probably damaging	1.000	0.947	phenotype	06/15/2016
13	394612		Cdh9	0.167	R5050	G1	225	Y		15	16778147	F16S	T	C	missense		Het	probably benign	0.116	0.216	phenotype	06/15/2016
14	394603		Cdkl1	0.190	R5050	G1	225	Y		12	69757240	K141R	T	C	missense		Het	probably damaging	1.000	0.164	phenotype	06/15/2016
15	394591		Chd4	1.000	R5050	G1	225	Y		6	125107480	Y692H	T	C	missense		Het	probably damaging	0.998	0.200	phenotype	06/15/2016
16	394604		Dhrs7	0.082	R5050	G1	225	Y		12	72657410	D104V	T	A	missense		Het	probably damaging	0.999	0.355	phenotype	06/15/2016
17	394575		Dhtkd1	0.000	R5050	G1	225	Y		2	5917689	L553Q	A	T	missense		Het	probably benign	0.003	0.060	phenotype	06/15/2016
18	394571		Dnah7a	0.135	R5050	G1	225	Y		1	53497096	D2596A	T	G	missense		Het	probably benign	0.006	0.094		06/15/2016
19	394598		Dync1li2	0.257	R5050	G1	225	Y		8	104437441	K151E	T	C	missense		Het	probably damaging	0.999	0.509	phenotype	06/15/2016
20	394624		Eno4	0.079	R5050	G1	225	Y		19	58955496	H297Y	C	T	missense		Het	probably benign	0.001	0.090	phenotype	06/15/2016
21	394619		Epg5	0.942	R5050	G1	225	Y		18	77975941	D976E	T	A	missense		Het	possibly damaging	0.545	0.122	phenotype	06/15/2016
22	394623		Fam160b1	0.178	R5050	G1	108	Y		19	57383170	F571L	T	A	missense		Het	probably damaging	1.000	0.409		06/15/2016
23	394596		Gm1966	0.108	R5050	G1	225	Y		7	106596972		T	C	exon		Het	noncoding transcript				06/15/2016
24	394597		Gm4553		R5050	G1	225	N		7	142165036	K218N	C	A	missense		Het	unknown				06/15/2016
25	394573		Gm4788	0.070	R5050	G1	225	Y		1	139736840	I494F	T	A	missense		Het	probably damaging	0.994	0.647		06/15/2016
26	394608		Gpld1	0.000	R5050	G1	225	Y		13	24962756	T234S	A	T	missense		Het	probably benign	0.001	0.060	phenotype	06/15/2016
27	394588		Gtpbp6	0.000	R5050	G1	111	Y		5	110104701		A	T	unclassified		Het	probably benign			phenotype	06/15/2016
28	394622		Gucy2g	0.000	R5050	G1	225	Y		19	55240935	E101G	T	C	missense		Het	probably benign	0.047	0.090	phenotype	06/15/2016
29	394615		Hira	1.000	R5050	G1	225	Y		16	18925859	R442K	G	A	missense		Het	possibly damaging	0.752	0.065	phenotype	06/15/2016
30	394582		Hrh3	0.281	R5050	G1	158	Y		2	180100557	L394P	A	G	missense		Het	probably damaging	1.000	0.864	phenotype	06/15/2016
31	394589		Igkv1-110	0.251	R5050	G1	225	Y		6	68271192	F95Y	T	A	missense		Het	probably damaging	0.997	0.647		06/15/2016
32	394583		Iqgap3	0.281	R5050	G1	225	Y		3	88090186	V223G	T	G	missense		Het	probably damaging	0.997	0.231		06/15/2016
33	394606		Itpk1	0.916	R5050	G1	187	Y		12	102704810	T3A	T	C	missense		Het	probably damaging	0.999	0.075	phenotype	06/15/2016
34	458147		Jag1	1.000	R5050	G1	225	Y		2	137085154	V895A	A	G	missense		Het	possibly damaging	0.712	0.722	phenotype	02/17/2017
35	458148		Kazn	0.246	R5050	G1	48	Y		4	142118203		G	A	unclassified		Het	probably benign		0.208	phenotype	02/17/2017
36	394578		Large2	0.000	R5050	G1	225	Y		2	92367779	L282Q	A	T	missense		Het	probably benign	0.053	0.132	phenotype	06/15/2016
37	394605		Lgmn	0.000	R5050	G1	225	Y		12	102403421		A	G	splice site	6 bp	Het	probably null		0.976	phenotype	06/15/2016
38	394577		Lrp4	0.612	R5050	G1	218	Y		2	91492422	I1119F	A	T	missense		Het	probably benign	0.225	0.163	phenotype	06/15/2016
39	394572		Map3k19	0.091	R5050	G1	225	Y		1	127823562	H684R	T	C	missense		Het	probably benign	0.213	0.194		06/15/2016
40	394609		Mier3	0.757	R5050	G1	209	Y		13	111714573	A367V	C	T	missense		Het	possibly damaging	0.944	0.319		06/15/2016
41	394586		Mpdz	0.000	R5050	G1	225	Y		4	81295448	V1579A	A	G	missense		Het	probably benign	0.003	0.064	phenotype	06/15/2016
42	458151		Mroh2b	0.105	R5050	G1	225	Y		15	4900450	D6V	A	T	missense		Het	possibly damaging	0.823	0.179		02/17/2017
43	394581		Myh7b	0.000	R5050	G1	225	Y		2	155631750	I1568V	A	G	missense		Het	probably benign	0.001	0.068	phenotype	06/15/2016
44	394595		Olfr675	0.287	R5050	G1	225	Y		7	105024387	I198F	T	A	missense		Het	probably damaging	1.000	0.421	phenotype	06/15/2016
45	458149		Plch2	0.000	R5050	G1	23	Y		4	155043309		C	T	intron		Het	probably benign			phenotype	02/17/2017
46	394600		Plek	0.173	R5050	G1	225	Y		11	16995216	D38G	T	C	missense		Het	probably damaging	0.979	0.637	phenotype	06/15/2016
47	394614		Polr2f	1.000	R5050	G1	210	Y		15	79144662		A	G	unclassified		Het	probably benign		0.086	phenotype	06/15/2016
48	394616		Samsn1	0.000	R5050	G1	225	Y		16	75888757	S38P	A	G	missense		Het	probably benign	0.000	0.090	phenotype	06/15/2016
49	394620		Sf1	1.000	R5050	G1	225	Y		19	6372559	T248I	C	T	missense		Het	probably damaging	0.999	0.583	phenotype	06/15/2016
50	394584		Sgms2	0.163	R5050	G1	225	Y		3	131330356	V232M	C	T	missense		Het	probably benign	0.000	0.090	phenotype	06/15/2016
51	394613		Sharpin	0.300	R5050	G1	197	Y		15	76348330	L160H	A	T	missense		Het	probably damaging	0.997	0.085	phenotype	06/15/2016
52	394593		Sympk	0.964	R5050	G1	225	Y		7	19036042	R215C	C	T	missense		Het	probably benign	0.192	0.191	phenotype	06/15/2016
53	394599		Syn3	0.000	R5050	G1	225	Y		10	86407668	T136A	T	C	missense		Het	probably benign	0.047	0.144	phenotype	06/15/2016
54	394602		Tcam1	0.000	R5050	G1	225	Y		11	106285452	V335M	G	A	missense		Het	possibly damaging	0.928	0.179	phenotype	06/15/2016
55	394607		Tedc1	1.000	R5050	G1	225	Y		12	113156705	V56L	G	T	missense		Het	possibly damaging	0.863	0.145		06/15/2016
56	394594		Tenm4	1.000	R5050	G1	225	Y		7	96895788	L2337P	T	C	missense		Het	probably damaging	1.000	0.894	phenotype	06/15/2016
57	394576		Ttn	1.000	R5050	G1	225	Y		2	76884811		G	A	intron		Het	probably benign		0.095	phenotype	06/15/2016
58	458150		Tysnd1	0.097	R5050	G1	71	Y		10	61696271	I234N	T	A	missense		Het	probably damaging	0.998	0.358	phenotype	02/17/2017
59	394592		Vmn2r51	0.089	R5050	G1	225	Y		7	10100422	K230E	T	C	missense		Het	probably damaging	0.994	0.647		06/15/2016
[records 1 to 59 of 59]