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Incidental Mutations

53 incidental mutations are currently displayed, and affect 53 genes.

11 are Possibly Damaging.

18 are Probably Damaging.

15 are Probably Benign.

5 are Probably Null.

2 create premature stop codons.

3 are critical splice junction mutations.

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Mutations in Coding Regions/Splice Sites Identified by Next-Gen Sequencing

[records 1 to 53 of 53] 10 25 50 100 500 1000 per page Full List
	ID	Source UTSW APN	Gene	E-score	Stock #	Gen G0 G0' G1 G2 G3 G3R F1 F2 F3 C0 C1 C2 C3 D1 HES IPS A3	Quality -	Vld Y N ?	Strain	Chr 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 X Y	Position	Mutation A R N D C E Q G H I L K M F P S T W Y V * A R N D C E Q G H I L K M F P S T W Y V *	Ref A C G T -	Var A C G T -	Type makesense missense nonsense start codon destroyed start gained synonymous splice acceptor site splice donor site critical splice acceptor site critical splice donor site splice site large deletion large insertion rearrangement small deletion small insertion exon frame shift intragenic intron utr 3 prime utr 5 prime unclassified	Exon Dist	Zygosity Homo Het Hemi Null	Predicted Effect unknown probably benign probably null possibly damaging probably damaging noncoding transcript silent not run no transcript	PPH Score -	Meta Score	MGI Phenotype available none listed	Posted
1	396740		0610010F05Rik	0.174	R5156	G1	225	Y		11	23593424		A	G	critical splice donor site	2 bp	Het	probably null		0.949		06/21/2016
2	396752		4921513D11Rik		R5156	G1	225	N		17	79628209		G	T	intron		Het	probably benign				06/21/2016
3	396736		Apeh	0.000	R5156	G1	225	Y		9	108094287	A29T	C	T	missense		Het	probably damaging	0.999	0.357	phenotype	06/21/2016
4	396721		Arap2	0.000	R5156	G1	225	Y		5	62669181	Y1013*	A	T	nonsense		Het	probably null		0.976	phenotype	06/21/2016
5	396706		Arhgef4	0.000	R5156	G1	225	Y		1	34723274	E537G	A	G	missense		Het	unknown		0.119	phenotype	06/21/2016
6	396734		Asf1b	0.000	R5156	G1	183	Y		8	83955911	F28S	T	C	missense		Het	probably damaging	0.999	0.960	phenotype	06/21/2016
7	396709		Cd46	0.000	R5156	G1	225	Y		1	195085385	I123L	T	A	missense		Het	possibly damaging	0.902	0.179	phenotype	06/21/2016
8	470607		Cdca7	0.155	R5156	G1	225	Y		2	72479026	T48S	A	T	missense		Het	probably damaging	0.996	0.074	phenotype	03/23/2017
9	396753		Cfap53	0.103	R5156	G1	225	Y		18	74359767		T	A	utr 3 prime		Het	probably benign		0.090	phenotype	06/21/2016
10	396719		Clca3a2	0.163	R5156	G1	225	Y		3	144805838	T599S	T	A	missense		Het	probably benign	0.262	0.090		06/21/2016
11	396718		Csf1	0.792	R5156	G1	225	Y		3	107748936	T148S	T	A	missense		Het	probably benign	0.006	0.090	phenotype	06/21/2016
12	396732		Dmbt1	0.223	R5156	G1	225	Y		7	131097670		T	C	critical splice donor site	2 bp	Het	probably null		0.949	phenotype	06/21/2016
13	396728		Dmpk	0.579	R5156	G1	225	N		7	19084125	D44G	A	G	missense		Het	probably damaging	0.999		phenotype	06/21/2016
14	396738		Dnajb12	0.076	R5156	G1	225	Y		10	59892960	N223K	T	A	missense		Het	probably damaging	0.999	0.647	phenotype	06/21/2016
15	396745		Dync1h1	1.000	R5156	G1	225	Y		12	110628830	M1392K	T	A	missense		Het	probably benign	0.001	0.072	phenotype	06/21/2016
16	396733		Edrf1	0.444	R5156	G1	225	Y		7	133660179	A867V	C	T	missense		Het	probably damaging	1.000	0.300	phenotype	06/21/2016
17	396754		Efemp2	1.000	R5156	G1	225	Y		19	5477678	C94S	T	A	missense		Het	possibly damaging	0.931	0.966	phenotype	06/21/2016
18	396720		Epha8	0.000	R5156	G1	225	Y		4	136938726	S373N	C	T	missense		Het	probably benign	0.139	0.089	phenotype	06/21/2016
19	396725		Foxk1	0.665	R5156	G1	211	Y		5	142448833	D284G	A	G	missense		Het	possibly damaging	0.876	0.094	phenotype	06/21/2016
20	396724		Fzd10	0.000	R5156	G1	225	Y		5	128601302	R29S	C	A	missense		Het	possibly damaging	0.679	0.103	phenotype	06/21/2016
21	396712		Gm13991	0.135	R5156	G1	225	Y		2	116528184		T	C	exon		Het	noncoding transcript		0.435		06/21/2016
22	396730		Gm6818	0.162	R5156	G1	225	Y		7	38402047		A	T	exon		Het	noncoding transcript				06/21/2016
23	396735		Hydin	0.603	R5156	G1	225	Y		8	110609701	C5037S	T	A	missense		Het	probably benign	0.003	0.090	phenotype	06/21/2016
24	396739		Ikzf1	0.000	R5156	G1	225	Y		11	11769448	M492K	T	A	missense		Het	probably damaging	0.999	0.963	phenotype	06/21/2016
25	396743		Krt20	0.071	R5156	G1	225	Y		11	99430053	S394R	G	T	missense		Het	possibly damaging	0.917	0.086	phenotype	06/21/2016
26	396716		Lrrc71	0.000	R5156	G1	225	Y		3	87745787	R107S	T	A	missense		Het	probably benign	0.073	0.090		06/21/2016
27	396744		Mia2	0.955	R5156	G1	225	Y		12	59172537	T436A	A	G	missense		Het	possibly damaging	0.944	0.179	phenotype	06/21/2016
28	396750		Muc19	0.168	R5156	G1	225	Y		15	91900420		T	A	exon		Het	noncoding transcript		0.087	phenotype	06/21/2016
29	396708		Neu4	0.000	R5156	G1	225	Y		1	94024455	V182A	T	C	missense		Het	probably damaging	0.999	0.456	phenotype	06/21/2016
30	396717		Notch2	1.000	R5156	G1	225	Y		3	98124310	F1167V	T	G	missense		Het	possibly damaging	0.529	0.095	phenotype	06/21/2016
31	396756		Nrap	0.000	R5156	G1	225	Y		19	56371845	M189T	A	G	missense		Het	possibly damaging	0.938	0.123		06/21/2016
32	396741		Nt5m	0.073	R5156	G1	174	Y		11	59874661	I172F	A	T	missense		Het	probably damaging	0.996	0.359	phenotype	06/21/2016
33	396711		Olfr1138	0.116	R5156	G1	225	Y		2	87737775	P183L	G	A	missense		Het	possibly damaging	0.946	0.408	phenotype	06/21/2016
34	396755		Olfr1474	0.082	R5156	G1	225	Y		19	13471673	K234N	G	T	missense		Het	probably damaging	1.000	0.647	phenotype	06/21/2016
35	396710		Olfr228	0.128	R5156	G1	225	Y		2	86483018	C241*	A	T	nonsense		Het	probably null		0.972	phenotype	06/21/2016
36	396727		Plekha5	0.336	R5156	G1	225	Y		6	140426528	T68M	C	T	missense		Het	probably damaging	1.000	0.647		06/21/2016
37	470608		Ppef2	0.000	R5156	G1	225	Y		5	92244602		A	G	critical splice donor site	2 bp	Het	probably null			phenotype	03/23/2017
38	396729		Ppp1r37	0.172	R5156	G1	90	N		7	19561975		T	C	unclassified		Het	probably benign				06/21/2016
39	470609		Rfx4	1.000	R5156	G1	225	Y		10	84868354	Y238H	T	C	missense		Het	probably damaging	0.999	0.080	phenotype	03/23/2017
40	396726		Sec13	0.955	R5156	G1	225	Y		6	113730876	A161V	G	A	missense		Het	probably benign	0.048	0.183	phenotype	06/21/2016
41	396749		Serhl	0.079	R5156	G1	225	Y		15	83102694		G	A	unclassified		Het	probably benign				06/21/2016
42	396714		Slco4a1	0.071	R5156	G1	225	Y		2	180472779	V588A	T	C	missense		Het	probably benign	0.013	0.090		06/21/2016
43	396715		Slitrk3	0.694	R5156	G1	225	Y		3	73049259	T727A	T	C	missense		Het	probably benign	0.000	0.063	phenotype	06/21/2016
44	470606		Sp100	0.234	R5156	G1	225	Y		1	85673683	D241E	T	A	missense		Het	probably damaging	1.000	0.078		03/23/2017
45	396713		Spata2	0.000	R5156	G1	225	Y		2	167483574	H442N	G	T	missense		Het	probably damaging	0.961	0.083	phenotype	06/21/2016
46	396707		Speg	1.000	R5156	G1	225	Y		1	75428087	V2588A	T	C	missense		Het	probably damaging	0.987	0.063	phenotype	06/21/2016
47	396742		Tnfsf12	0.131	R5156	G1	225	Y		11	69687329	S141P	A	G	missense		Het	probably damaging	1.000	0.663	phenotype	06/21/2016
48	396737		Trank1	0.000	R5156	G1	225	Y		9	111390694	I2166M	A	G	missense		Het	probably damaging	0.998	0.068		06/21/2016
49	396751		Trim10	0.137	R5156	G1	225	Y		17	36877056	V388E	T	A	missense		Het	probably damaging	0.990	0.799	phenotype	06/21/2016
50	396748		Ttc23l	0.093	R5156	G1	225	Y		15	10551550	T30K	G	T	missense		Het	possibly damaging	0.955	0.153		06/21/2016
51	396723		Vmn2r10	0.081	R5156	G1	225	Y		5	108995600	V828A	A	G	missense		Het	probably benign	0.112	0.090		06/21/2016
52	396731		Vmn2r75	0.071	R5156	G1	225	Y		7	86164228	L455F	T	A	missense		Het	possibly damaging	0.510	0.179		06/21/2016
53	396747		Vwa8	0.000	R5156	G1	225	Y		14	78984226	S541T	T	A	missense		Het	probably benign	0.003	0.084		06/21/2016
[records 1 to 53 of 53]