Home
Phenotypic Mutations
Incidental Mutations
Engineered Mutations
Candidate Explorer
Protocols
Mutation Statistics
About
Contact
Links
Request Mice
Beutler Lab
APN
Strains @ MMRRC
Search Phenotypes
NEW
Candidate Explorer
Staff Login
Download
Incidental Mutations
46
incidental mutations are currently displayed, and affect
46
genes.
10
are Possibly Damaging.
13
are Probably Damaging.
17
are Probably Benign.
6
are Probably Null.
3
create premature stop codons.
0
are critical splice junction mutations.
Mutations in Coding Regions/Splice Sites Identified by Next-Gen Sequencing
[records 1 to 46 of 46]
10
25
50
100
500
1000
per page
Full List
ID
Source
UTSW
APN
Gene
E-score
Stock #
Gen
G0
G0'
G1
G2
G3
G3R
F1
F2
F3
C0
C1
C2
C3
D1
HES
IPS
A3
Quality
-
Vld
Y
N
?
Strain
Chr
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
X
Y
Position
Mutation
A
R
N
D
C
E
Q
G
H
I
L
K
M
F
P
S
T
W
Y
V
*
A
R
N
D
C
E
Q
G
H
I
L
K
M
F
P
S
T
W
Y
V
*
Ref
A
C
G
T
-
Var
A
C
G
T
-
Type
makesense
missense
nonsense
start codon destroyed
start gained
synonymous
splice acceptor site
splice donor site
critical splice acceptor site
critical splice donor site
splice site
large deletion
large insertion
rearrangement
small deletion
small insertion
exon
frame shift
intragenic
intron
utr 3 prime
utr 5 prime
unclassified
Exon Dist
Zygosity
Homo
Het
Hemi
Null
Predicted Effect
unknown
probably benign
probably null
possibly damaging
probably damaging
noncoding transcript
silent
not run
no transcript
PPH Score
-
Meta Score
MGI Phenotype
available
none listed
Posted
1
487237
Adcy7
0.329
R6133
G1
225.01
Y
8
88325439
T912A
A
G
missense
Het
possibly damaging
0.844
0.093
phenotype
10/10/2017
2
487242
Akap12
0.095
R6133
G1
225.01
Y
10
4355178
G663C
G
T
missense
Het
probably benign
0.045
phenotype
10/10/2017
3
487226
Akap2
0.137
R6133
G1
192.01
Y
4
57855516
Q525*
C
T
nonsense
Het
probably null
phenotype
10/10/2017
4
487256
Ankhd1
0.000
R6133
G1
225.01
Y
18
36625126
S958P
T
C
missense
Het
possibly damaging
0.766
10/10/2017
5
487238
Cmtm2a
0.055
R6133
G1
225.01
Y
8
104292730
I76V
T
C
missense
Het
probably benign
0.288
0.135
10/10/2017
6
487235
Cpxm2
0.070
R6133
G1
225.01
Y
7
132128453
P146S
G
A
missense
Het
probably damaging
1.000
10/10/2017
7
487221
Cubn
1.000
R6133
G1
225.01
Y
2
13308618
V3047A
A
G
missense
Het
probably benign
0.292
phenotype
10/10/2017
8
487216
Dgkd
0.804
R6133
G1
225.01
Y
1
87938240
V198E
T
A
missense
Het
possibly damaging
0.932
0.570
phenotype
10/10/2017
9
487234
Dnah3
0.093
R6133
G1
225.01
Y
7
120086246
M181K
A
T
missense
Het
probably benign
0.101
phenotype
10/10/2017
10
487214
Dnah7a
0.152
R6133
G1
225.01
Y
1
53419655
T3775A
T
C
missense
Het
probably benign
0.047
10/10/2017
11
487255
Dsg2
0.207
R6133
G1
225.01
Y
18
20590089
I391V
A
G
missense
Het
probably benign
0.002
phenotype
10/10/2017
12
512267
Ebi3
0.073
R6133
G1
71.01
Y
17
55954311
V69E
T
A
missense
Het
probably benign
0.317
0.090
phenotype
04/19/2018
13
487215
Fn1
1.000
R6133
G1
225.01
Y
1
71597727
T1998A
T
C
missense
Het
probably damaging
0.997
phenotype
10/10/2017
14
487225
Frmpd1
0.000
R6133
G1
225.01
Y
4
45284915
H1245Q
T
A
missense
Het
probably benign
0.015
0.068
10/10/2017
15
487218
Gm7145
0.267
R6133
G1
225.01
Y
1
117985888
C167S
T
A
missense
Het
probably damaging
1.000
10/10/2017
16
487239
Hydin
0.631
R6133
G1
225.01
Y
8
110601276
T4805I
C
T
missense
Het
probably benign
0.002
0.090
phenotype
10/10/2017
17
487246
Itgb4
1.000
R6133
G1
225.01
Y
11
115984157
R447W
C
T
missense
Het
probably benign
0.002
0.090
phenotype
10/10/2017
18
487249
Kcnma1
0.862
R6133
G1
94.02
Y
14
24003868
M21I
C
T
missense
Het
probably damaging
0.982
phenotype
10/10/2017
19
487247
Lrfn5
0.099
R6133
G1
225.01
Y
12
61843788
D621G
A
G
missense
Het
probably benign
0.225
0.069
phenotype
10/10/2017
20
487251
Lrrc15
0.000
R6133
G1
225.01
Y
16
30274236
G95D
C
T
missense
Het
probably benign
0.110
10/10/2017
21
487244
Mex3d
0.279
R6133
G1
192.01
Y
10
80386786
L212P
A
G
missense
Het
probably damaging
0.989
10/10/2017
22
487229
Mmel1
0.173
R6133
G1
225.01
Y
4
154895018
H728Y
C
T
missense
Het
probably damaging
1.000
0.765
phenotype
10/10/2017
23
487248
Naip1
0.000
R6133
G1
225.01
Y
13
100444643
V32A
A
G
missense
Het
probably benign
0.097
phenotype
10/10/2017
24
487220
Nsl1
0.932
R6133
G1
225.01
Y
1
191071206
L158P
T
C
missense
Het
probably damaging
0.993
phenotype
10/10/2017
25
487233
Olfr638
0.244
R6133
G1
225.01
Y
7
104003325
T17S
A
T
missense
Het
possibly damaging
0.577
0.191
phenotype
10/10/2017
26
487245
Olfr771
0.069
R6133
G1
225.01
Y
10
129160883
L34F
G
A
missense
Het
possibly damaging
0.551
phenotype
10/10/2017
27
487241
Olfr883
0.099
R6133
G1
217.47
Y
9
38026540
ATTGCTGTTT
ATTGCTGTTTGCTGTTT
frame shift
Het
probably null
0.976
phenotype
10/10/2017
28
487243
Pcdh15
0.000
R6133
G1
225.01
Y
10
74645973
A
T
splice site
1596 bp
Het
probably null
phenotype
10/10/2017
29
487227
Pramef20
0.000
R6133
G1
225.01
Y
4
144377777
R53G
T
C
missense
Het
possibly damaging
0.805
0.179
10/10/2017
30
487224
Ptpn1
0.905
R6133
G1
225.01
Y
2
167967796
V108A
T
C
missense
Het
possibly damaging
0.944
0.758
phenotype
10/10/2017
31
487231
Rad9b
1.000
R6133
G1
225.01
Y
5
122339768
N182D
T
C
missense
Het
possibly damaging
0.788
phenotype
10/10/2017
32
487250
Rp1l1
0.087
R6133
G1
225.01
Y
14
64030096
P1044S
C
T
missense
Het
probably damaging
1.000
phenotype
10/10/2017
33
487223
Scn2a
1.000
R6133
G1
225.01
Y
2
65743104
V1433I
G
A
missense
Het
probably benign
0.349
0.075
phenotype
10/10/2017
34
512266
Ssrp1
1.000
R6133
G1
225.01
Y
2
85045339
T
G
intron
Het
probably benign
0.090
phenotype
04/19/2018
35
487219
Suco
0.594
R6133
G1
225.01
Y
1
161835183
K560*
T
A
nonsense
Het
probably null
phenotype
10/10/2017
36
487230
Tbx3
1.000
R6133
G1
135.01
Y
5
119680953
V531A
T
C
missense
Het
probably benign
0.186
phenotype
10/10/2017
37
487252
Tmem30c
0.058
R6133
G1
225.01
Y
16
57277737
Y107C
T
C
missense
Het
probably damaging
1.000
10/10/2017
38
501818
Topbp1
1.000
R6133
G1
225.01
Y
9
103311764
T
A
splice site
244 bp
Het
probably null
phenotype
12/04/2017
39
487236
Trpm5
0.077
R6133
G1
225.01
Y
7
143088951
D86E
A
T
missense
Het
probably damaging
0.976
phenotype
10/10/2017
40
487240
Urb2
0.957
R6133
G1
225.01
Y
8
124028561
Q336*
C
T
nonsense
Het
probably null
10/10/2017
41
487232
Vmn2r43
0.105
R6133
G1
89.01
N
7
8244971
F731S
A
G
missense
Het
probably damaging
1.000
10/10/2017
42
487213
Xkr9
0.076
R6133
G1
225.01
Y
1
13684135
T118A
A
G
missense
Het
probably benign
0.009
10/10/2017
43
487217
Zcchc2
0.184
R6133
G1
225.01
Y
1
106019879
K117N
A
C
missense
Het
probably damaging
1.000
10/10/2017
44
487253
Zfp52
0.207
R6133
G1
225.01
Y
17
21560471
Y194H
T
C
missense
Het
probably damaging
0.998
0.647
10/10/2017
45
487254
Zfp763
0.000
R6133
G1
225.01
Y
17
33018701
C490Y
C
T
missense
Het
possibly damaging
0.752
0.179
10/10/2017
46
487222
Zmynd19
0.000
R6133
G1
225.01
Y
2
24958119
R148L
G
T
missense
Het
possibly damaging
0.712
phenotype
10/10/2017
[records 1 to 46 of 46]