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Incidental Mutations

57 incidental mutations are currently displayed, and affect 57 genes.

10 are Possibly Damaging.

22 are Probably Damaging.

19 are Probably Benign.

4 are Probably Null.

2 create premature stop codons.

2 are critical splice junction mutations.

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Mutations in Coding Regions/Splice Sites Identified by Next-Gen Sequencing

[records 1 to 57 of 57] 10 25 50 100 500 1000 per page Full List
	ID	Source UTSW APN	Gene	E-score	Stock #	Gen G0 G0' G1 G2 G3 G3R F1 F2 F3 C0 C1 C2 C3 D1 HES IPS A3	Quality -	Vld Y N ?	Strain	Chr 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 X Y	Position	Mutation A R N D C E Q G H I L K M F P S T W Y V * A R N D C E Q G H I L K M F P S T W Y V *	Ref A C G T -	Var A C G T -	Type makesense missense nonsense start codon destroyed start gained synonymous splice acceptor site splice donor site critical splice acceptor site critical splice donor site splice site large deletion large insertion rearrangement small deletion small insertion exon frame shift intragenic intron utr 3 prime utr 5 prime unclassified	Exon Dist	Zygosity Homo Het Hemi Null	Predicted Effect unknown probably benign probably null possibly damaging probably damaging noncoding transcript silent not run no transcript	PPH Score -	Meta Score	MGI Phenotype available none listed	Posted
1	538128		1520401A03Rik	0.067	R6892	G1	225.01	Y		17	23712354	L193P	A	G	missense		Het	probably damaging	0.974			11/06/2018
2	538115		4930442H23Rik	0.122	R6892	G1	225.01	Y		10	81183144		C	A	unclassified		Het	probably benign				11/06/2018
3	538105		4933421I07Rik	0.061	R6892	G1	225.01	Y		7	42446407	Q139R	T	C	missense		Het	probably benign	0.353			11/06/2018
4	538133		A930002H24Rik	0.129	R6892	G1	156.01	Y		17	63863764	V10M	C	T	missense		Het	unknown				11/06/2018
5	538090		Acvr2a	0.000	R6892	G1	225.01	Y		2	48897075	L394Q	T	A	missense		Het	probably damaging	1.000		phenotype	11/06/2018
6	538126		Ano6	0.353	R6892	G1	225.01	Y		15	95967624	Y830H	T	C	missense		Het	probably damaging	1.000		phenotype	11/06/2018
7	538091		Atp8b4	0.056	R6892	G1	225.01	Y		2	126343002	I914F	T	A	missense		Het	possibly damaging	0.935	0.120	phenotype	11/06/2018
8	538083		Cab39	0.954	R6892	G1	225.01	Y		1	85848377	D265G	A	G	missense		Het	probably damaging	1.000	0.960		11/06/2018
9	538107		Capn5	0.109	R6892	G1	225.01	Y		7	98135941	W109R	A	T	missense		Het	probably damaging	0.999		phenotype	11/06/2018
10	538084		Cdk18	0.372	R6892	G1	200.01	Y		1	132122110	T44K	G	T	missense		Het	probably benign	0.011	0.090		11/06/2018
11	538110		Cdt1	0.963	R6892	G1	225.01	Y		8	122570212	N248K	T	A	missense		Het	probably damaging	1.000		phenotype	11/06/2018
12	538100		Cpa4	0.000	R6892	G1	225.01	Y		6	30583629	R248L	G	T	missense		Het	probably benign	0.000		phenotype	11/06/2018
13	538137		Cpt1a	1.000	R6892	G1	225.01	Y		19	3371660	V481M	G	A	missense		Het	probably benign	0.003		phenotype	11/06/2018
14	538099		Cyp3a11	0.000	R6892	G1	225.01	Y		5	145860448	L374F	G	A	missense		Het	probably damaging	0.979			11/06/2018
15	538123		Dcdc2a	0.199	R6892	G1	225.01	Y		13	25056460	N64D	A	G	missense		Het	probably damaging	0.997	0.336	phenotype	11/06/2018
16	538136		Dmxl1	0.936	R6892	G1	225.01	Y		18	49920902	R2525Q	G	A	missense		Het	probably damaging	0.978	0.128	phenotype	11/06/2018
17	538111		Dscaml1	0.617	R6892	G1	225.01	N		9	45683830	V744M	G	A	missense		Het	probably damaging	0.986		phenotype	11/06/2018
18	538122		Dync1h1	1.000	R6892	G1	225.01	Y		12	110638901	E2391K	G	A	missense		Het	probably benign	0.001		phenotype	11/06/2018
19	538120		Ezh1	0.000	R6892	G1	225.01	Y		11	101199361	Y522*	A	T	nonsense		Het	probably null			phenotype	11/06/2018
20	538125		Fzd3	1.000	R6892	G1	225.01	Y		14	65209881	A533G	G	C	missense		Het	possibly damaging	0.904		phenotype	11/06/2018
21	538093		Gm14403	0.139	R6892	G1	117.01	N		2	177509247	C329G	T	G	missense		Het	probably damaging	1.000			11/06/2018
22	538106		Gm17067	0.076	R6892	G1	225.01	Y		7	42710675		A	C	critical splice donor site	2 bp	Het	probably null				11/06/2018
23	538094		Gm38119	0.169	R6892	G1	225.01	Y		3	92738222	C22R	A	G	missense		Het	unknown				11/06/2018
24	538082		Gtf3c3	0.964	R6892	G1	225.01	Y		1	54415941	S588P	A	G	missense		Het	probably benign	0.001		phenotype	11/06/2018
25	538129		Ift140	1.000	R6892	G1	225.01	Y		17	25020546	E59G	A	G	missense		Het	possibly damaging	0.951		phenotype	11/06/2018
26	538097		Ints1	1.000	R6892	G1	225.01	Y		5	139767828	M683K	A	T	missense		Het	probably damaging	0.987	0.427	phenotype	11/06/2018
27	538135		Iws1	0.956	R6892	G1	225.01	Y		18	32086274	M470V	A	G	missense		Het	probably damaging	0.987			11/06/2018
28	538088		Mptx1	0.105	R6892	G1	225.01	Y		1	174332265	R46G	A	G	missense		Het	probably benign	0.090	0.090		11/06/2018
29	538114		Nhsl1	0.000	R6892	G1	225.01	Y		10	18524343	T439I	C	T	missense		Het	probably damaging	1.000			11/06/2018
30	538108		Olfr517	0.132	R6892	G1	225.01	Y		7	108868515	L213P	A	G	missense		Het	probably damaging	1.000		phenotype	11/06/2018
31	538104		Peg3	0.000	R6892	G1	225.01	Y		7	6708899	S1108N	C	T	missense		Het	possibly damaging	0.577	0.179	phenotype	11/06/2018
32	538096		Pgm2	0.865	R6892	G1	225.01	Y		4	99929708	E48G	A	G	missense		Het	probably benign	0.000		phenotype	11/06/2018
33	538081		Pkhd1	0.118	R6892	G1	225.01	Y		1	20523515	T1458I	G	A	missense		Het	probably damaging	0.998		phenotype	11/06/2018
34	538101		Polr1a	1.000	R6892	G1	225.01	Y		6	71964712	D1068V	A	T	missense		Het	possibly damaging	0.721		phenotype	11/06/2018
35	538117		Ptprq	0.444	R6892	G1	225.01	Y		10	107576004	T1834A	T	C	missense		Het	probably benign	0.001		phenotype	11/06/2018
36	538089		Rapgef1	1.000	R6892	G1	225.01	Y		2	29699840		T	C	critical splice donor site	2 bp	Het	probably null			phenotype	11/06/2018
37	538085		Rgl1	0.341	R6892	G1	225.01	Y		1	152539940	D409E	A	T	missense		Het	probably benign	0.005	0.090	phenotype	11/06/2018
38	538086		Rgsl1	0.000	R6892	G1	225.01	Y		1	153821499	Y558*	G	T	nonsense		Het	probably null		0.976		11/06/2018
39	538134		Rock1	0.946	R6892	G1	225.01	Y		18	10122612	R403H	C	T	missense		Het	probably benign	0.001		phenotype	11/06/2018
40	538113		Scn11a	0.108	R6892	G1	225.01	Y		9	119806969	D304V	T	A	missense		Het	possibly damaging	0.529	0.179	phenotype	11/06/2018
41	538098		Sdk1	0.101	R6892	G1	225.01	Y		5	142046298	I1043F	A	T	missense		Het	probably benign	0.005	0.145	phenotype	11/06/2018
42	538095		Sgms2	0.163	R6892	G1	225.01	Y		3	131342154	Y24H	A	G	missense		Het	probably benign	0.000		phenotype	11/06/2018
43	538092		Sppl2a	0.084	R6892	G1	225.01	Y		2	126913575	I372T	A	G	missense		Het	probably damaging	0.997	0.801	phenotype	11/06/2018
44	538118		Sptbn1	1.000	R6892	G1	225.01	Y		11	30142187	M526T	A	G	missense		Het	probably benign	0.274	0.059	phenotype	11/06/2018
45	538127		Stxbp5l	0.000	R6892	G1	225.01	Y		16	37188629	S683T	A	T	missense		Het	possibly damaging	0.936		phenotype	11/06/2018
46	538124		Syk	1.000	R6892	G1	225.01	Y		13	52632898	R332S	A	T	missense		Het	probably benign	0.001	0.177	phenotype	11/06/2018
47	538121		Syne2	0.293	R6892	G1	225.01	Y		12	75962528	V2401E	T	A	missense		Het	probably damaging	0.980		phenotype	11/06/2018
48	538103		Tarm1	0.068	R6892	G1	225.01	Y		7	3497490	Y87C	T	C	missense		Het	probably damaging	0.998	0.810		11/06/2018
49	538130		Tbc1d22b	0.199	R6892	G1	225.01	Y		17	29595890	K378E	A	G	missense		Het	possibly damaging	0.795			11/06/2018
50	538131		Tcte1	0.000	R6892	G1	225.01	Y		17	45533157	T20A	A	G	missense		Het	probably benign	0.000	0.090		11/06/2018
51	538087		Tor1aip2	0.222	R6892	G1	225.01	Y		1	156065181	Y411F	A	T	missense		Het	possibly damaging	0.955	0.457		11/06/2018
52	538112		Trim43c	0.085	R6892	G1	225.01	Y		9	88844924	M267K	T	A	missense		Het	probably benign	0.355			11/06/2018
53	538132		Ubr2	0.867	R6892	G1	225.01	Y		17	46934108	Y1664S	T	G	missense		Het	probably damaging	0.994	0.066	phenotype	11/06/2018
54	538116		Uhrf1bp1l	0.385	R6892	G1	225.01	Y		10	89805123	V719I	G	A	missense		Het	probably benign	0.021			11/06/2018
55	538102		Vmn1r41	0.058	R6892	G1	225.01	N		6	89747181	Q235K	C	A	missense		Het	possibly damaging	0.502			11/06/2018
56	538109		Wdr17	0.000	R6892	G1	225.01	Y		8	54673596	T401A	T	C	missense		Het	probably damaging	0.996	0.164	phenotype	11/06/2018
57	538119		Zfp454	0.066	R6892	G1	225.01	Y		11	50873198	L469P	A	G	missense		Het	probably damaging	1.000			11/06/2018
[records 1 to 57 of 57]