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Incidental Mutations

71 incidental mutations are currently displayed, and affect 70 genes.

15 are Possibly Damaging.

27 are Probably Damaging.

16 are Probably Benign.

11 are Probably Null.

3 create premature stop codons.

2 are critical splice junction mutations.

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Mutations in Coding Regions/Splice Sites Identified by Next-Gen Sequencing

[records 1 to 71 of 71] 10 25 50 100 500 1000 per page Full List
	ID	Source UTSW APN	Gene	E-score	Stock #	Gen G0 G0' G1 G2 G3 G3R F1 F2 F3 C0 C1 C2 C3 D1 HES IPS A3	Quality -	Vld Y N ?	Strain	Chr 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 X Y	Position	Mutation A R N D C E Q G H I L K M F P S T W Y V * A R N D C E Q G H I L K M F P S T W Y V *	Ref A C G T -	Var A C G T -	Type makesense missense nonsense start codon destroyed start gained synonymous splice acceptor site splice donor site critical splice acceptor site critical splice donor site splice site large deletion large insertion rearrangement small deletion small insertion exon frame shift intragenic intron utr 3 prime utr 5 prime unclassified	Exon Dist	Zygosity Homo Het Hemi Null	Predicted Effect unknown probably benign probably null possibly damaging probably damaging noncoding transcript silent not run no transcript	PPH Score -	Meta Score	MGI Phenotype available none listed	Posted
1	546770		Acsm3	0.000	R7037	G1	225.01	Y		7	119768043	N33I	A	T	missense		Het	probably damaging	0.998		phenotype	05/13/2019
2	546787		Ahnak2	0.076	R7037	G1	225.01	Y		12	112774278	V314D	A	T	missense		Het	probably damaging	0.985			05/13/2019
3	546800		Arl14epl	0.117	R7037	G1	225.01	Y		18	46932443	C92G	T	G	missense		Het	probably benign	0.384			05/13/2019
4	546739		Atp6v1h	1.000	R7037	G1	225.01	Y		1	5149992	M423K	T	A	missense		Het	possibly damaging	0.766		phenotype	05/13/2019
5	546795		Baiap3	0.000	R7037	G1	225.01	Y		17	25243840	R1075C	G	A	missense		Het	probably benign	0.000	0.090	phenotype	05/13/2019
6	546745		Baz2b	0.269	R7037	G1	225.01	Y		2	59933670		C	T	critical splice donor site	1 bp	Het	probably null		0.948	phenotype	05/13/2019
7	546797		Bicral	1.000	R7037	G1	225.01	Y		17	46824634	H550R	T	C	missense		Het	probably benign	0.084		phenotype	05/13/2019
8	546765		C1rl	0.000	R7037	G1	225.01	Y		6	124508639	Y323C	A	G	missense		Het	probably damaging	1.000			05/13/2019
9	546777		Ccr9	0.059	R7037	G1	225.01	Y		9	123779971	H239Q	T	A	missense		Het	possibly damaging	0.522		phenotype	05/13/2019
10	546773		Cdh16	0.081	R7037	G1	225.01	Y		8	104617635	R91*	T	A	nonsense		Het	probably null		0.976	phenotype	05/13/2019
11	546761		Coro1c	0.000	R7037	G1	225.01	Y		5	113845396	F357S	A	G	missense		Het	possibly damaging	0.603	0.957	phenotype	05/13/2019
12	546762		Cpsf4		R7037	G1	225.01	Y		5	145176129	R141Q	G	A	missense		Het	possibly damaging	0.512		phenotype	05/13/2019
13	546742		Cryzl2	0.000	R7037	G1	225.01	Y		1	157470748	V236I	G	A	missense		Het	probably damaging	0.991			05/13/2019
14	546764		Cttnbp2	0.000	R7037	G1	225.01	Y		6	18435118	E247G	T	C	missense		Het	probably damaging	1.000		phenotype	05/13/2019
15	568445		Dbr1	1.000	R7037	G1	225.01	Y		9	99576568		T	A	splice site		Het	probably null			phenotype	07/31/2019
16	546752		Dclk1	0.736	R7037	G1	225.01	Y		3	55463048	S23P	T	C	missense		Het	probably damaging	0.999	0.160	phenotype	05/13/2019
17	568443		Diexf	0.968	R7037	G1	225.01	Y		1	193120723		A	C	splice site		Het	probably null				07/31/2019
18	546755		Dpyd	0.000	R7037	G1	225.01	Y		3	118899289	I361F	A	T	missense		Het	probably benign	0.003		phenotype	05/13/2019
19	546781		Elac2	1.000	R7037	G1	225.01	Y		11	64983711	E218G	A	G	missense		Het	probably benign	0.000		phenotype	05/13/2019
20	546798		Eml4	0.786	R7037	G1	225.01	Y		17	83425327	D136E	T	A	missense		Het	probably benign	0.044		phenotype	05/13/2019
21	546776		Fam198a	0.059	R7037	G1	225.01	Y		9	121965526	V249L	G	T	missense		Het	possibly damaging	0.612			05/13/2019
22	546766		Fam71e2	0.086	R7037	G1	225.01	Y		7	4758585		G	T	utr 3 prime		Het	probably benign				05/13/2019
23	546774		Foxred1	1.000	R7037	G1	225.01	Y		9	35207548	S223T	A	T	missense		Het	probably benign	0.039		phenotype	05/13/2019
24	546783		Gm11595	0.070	R7037	G1	225.01	N		11	99772648	C69R	A	G	missense		Het	unknown				05/13/2019
25	546747		Gm14124	0.077	R7037	G1	225.01	Y		2	150266456	V46F	G	T	missense		Het	possibly damaging	0.861	0.179		05/13/2019
26	546803		Gna14	0.167	R7037	G1	225.01	Y		19	16533764	H59L	A	T	missense		Het				phenotype	05/13/2019
27	546796		H2-Ab1	0.064	R7037	G1	225.01	Y		17	34267989	I239N	T	A	missense		Het	probably damaging	0.985		phenotype	05/13/2019
28	546743		Ints7	0.943	R7037	G1	225.01	Y		1	191619605	S809P	T	C	missense		Het	probably benign	0.155	0.296	phenotype	05/13/2019
29	546785		Itgb4	1.000	R7037	G1	225.01	Y		11	116005565	Y1379*	T	A	nonsense		Het	probably null			phenotype	05/13/2019
30	546804		Kank1	0.000	R7037	G1	225.01	Y		19	25430341	D1233G	A	G	missense		Het	probably damaging	0.999		phenotype	05/13/2019
31	546789		Kif13a	0.440	R7037	G1	225.01	Y		13	46752455	V671M	C	T	missense		Het	possibly damaging	0.949	0.076	phenotype	05/13/2019
32	546759		Lrrc66	0.060	R7037	G1	225.01	Y		5	73607161	D846E	A	T	missense		Het	probably benign	0.105			05/13/2019
33	546788		Lyst	0.330	R7037	G1	225.01	Y		13	13616666	H38R	A	G	missense		Het	probably damaging	0.999		phenotype	05/13/2019
34	546751		Mc3r	0.104	R7037	G1	225.01	Y		2	172249634	F259L	T	C	missense		Het	probably damaging	0.999	0.327	phenotype	05/13/2019
35	546767		Med25	1.000	R7037	G1	225.01	Y		7	44882782	Y384H	A	G	missense		Het	probably damaging	0.998		phenotype	05/13/2019
36	546763		Met	1.000	R7037	G1	225.01	Y		6	17547128		A	T	intron		Het	probably benign			phenotype	05/13/2019
37	546757		Mmp16	0.000	R7037	G1	225.01	Y		4	18116148	V584A	T	C	missense		Het	possibly damaging	0.948	0.139	phenotype	05/13/2019
38	546786		Mpp5	0.670	R7037	G1	225.01	Y		12	78797199	I59N	T	A	missense		Het	probably damaging	1.000		phenotype	05/13/2019
39	546768		Mrgprb3	0.075	R7037	G1	225.01	Y		7	48643194	L203P	A	G	missense		Het	probably damaging	0.996			05/13/2019
40	546801		Mus81	0.331	R7037	G1	225.01	Y		19	5486080	L185P	A	G	missense		Het	probably damaging	0.998		phenotype	05/13/2019
41	546760		Naaa	0.000	R7037	G1	225.01	Y		5	92277075	V75A	A	G	missense		Het	possibly damaging	0.464		phenotype	05/13/2019
42	546779		Obscn	0.859	R7037	G1	225.01	Y		11	59043929	T5292S	T	A	missense		Het	probably damaging	0.999		phenotype	05/13/2019
43	546780		Obscn	0.859	R7037	G1	104.01	Y		11	59052604	S4801G	T	C	missense		Het	probably damaging	0.980		phenotype	05/13/2019
44	546769		Olfr703	0.163	R7037	G1	225.01	Y		7	106845336	S242P	T	C	missense		Het	probably damaging	0.999		phenotype	05/13/2019
45	546758		Otof	0.226	R7037	G1	225.01	Y		5	30381538	D1112G	T	C	missense		Het	probably benign	0.322		phenotype	05/13/2019
46	546772		Pbx4	0.216	R7037	G1	225.01	Y		8	69864875	R170G	A	G	missense		Het	probably damaging	0.997		phenotype	05/13/2019
47	546749		Pigt	0.844	R7037	G1	214.46	Y		2	164499669		CCAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGATCTGTAACCACAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGATCTGTAACCACAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGAT	CCAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGATCTGTAACCACAGGCCAGTGAGTAGGTTTGTCTCTGTCTAGTGTGGAT	frame shift		Het	probably null			phenotype	05/13/2019
48	546805		Plce1	0.566	R7037	G1	225.01	Y		19	38702017	D715V	A	T	missense		Het	probably damaging	1.000	0.236	phenotype	05/13/2019
49	546741		Pms1	0.000	R7037	G1	225.01	Y		1	53207611	T311A	T	C	missense		Het	possibly damaging	0.950		phenotype	05/13/2019
50	546794		Popdc2	0.000	R7037	G1	225.01	Y		16	38374267	D350G	A	G	missense		Het	probably damaging	1.000	0.161	phenotype	05/13/2019
51	546750		Prex1	0.303	R7037	G1	225.01	Y		2	166587180	V661A	A	G	missense		Het	probably benign	0.049	0.090	phenotype	05/13/2019
52	546756		Ptbp2	1.000	R7037	G1	225.01	Y		3	119751908	Y130H	A	G	missense		Het	probably damaging	0.998		phenotype	05/13/2019
53	546778		Rev3l	1.000	R7037	G1	225.01	Y		10	39851975	R2707W	C	T	missense		Het	probably damaging	1.000	0.647	phenotype	05/13/2019
54	546792		Rpl37	0.960	R7037	G1	225.01	Y		15	5117703	R75K	G	A	missense		Het	probably null	0.005	0.124	phenotype	05/13/2019
55	546746		Ryr3	0.549	R7037	G1	225.01	Y		2	112949130	R259*	T	A	nonsense		Het	probably null		0.976	phenotype	05/13/2019
56	546744		Scai	0.420	R7037	G1	225.01	Y		2	39190621	S8T	A	T	missense		Het	probably benign	0.039		phenotype	05/13/2019
57	546784		Scn4a	1.000	R7037	G1	225.01	Y		11	106320900	L1430F	C	A	missense		Het	probably damaging	0.981		phenotype	05/13/2019
58	546793		Sema5a	1.000	R7037	G1	225.01	Y		15	32686847	K1035R	A	G	missense		Het	probably damaging	0.999	0.146	phenotype	05/13/2019
59	546791		Siah3	0.213	R7037	G1	225.01	Y		14	75525585	H92R	A	G	missense		Het	probably benign	0.007			05/13/2019
60	546753		Smc4	0.972	R7037	G1	225.01	Y		3	69018195	V342I	G	A	missense		Het	possibly damaging	0.668	0.073	phenotype	05/13/2019
61	546790		Spata31d1a	0.058	R7037	G1	225.01	Y		13	59700324	C1330Y	C	T	missense		Het	possibly damaging	0.956	0.179		05/13/2019
62	546740		St18	0.000	R7037	G1	225.01	Y		1	6803036	H332N	C	A	missense		Het	possibly damaging	0.650			05/13/2019
63	546754		Sycp1	0.519	R7037	G1	225.01	Y		3	102898934	E480D	T	A	missense		Het	possibly damaging	0.615	0.179	phenotype	05/13/2019
64	546782		Tex14	0.168	R7037	G1	225.01	Y		11	87497915	I323F	A	T	missense		Het	probably damaging	0.997		phenotype	05/13/2019
65	546802		Tm7sf2	0.000	R7037	G1	225.01	Y		19	6064077		A	T	critical splice donor site	2 bp	Het	probably null			phenotype	05/13/2019
66	546799		Tmem241	0.000	R7037	G1	225.01	Y		18	12113406	H62Q	G	T	missense		Het	probably benign	0.024	0.090		05/13/2019
67	568444		Tmem54	0.066	R7037	G1	225.01	Y		4	129110801		T	A	splice site		Het	probably null				07/31/2019
68	546748		Tomm34	0.173	R7037	G1	225.01	Y		2	164070478	L39P	A	G	missense		Het	probably damaging	0.998	0.343	phenotype	05/13/2019
69	546771		Triml2	0.074	R7037	G1	225.01	Y		8	43193536	V354D	T	A	missense		Het	probably damaging	0.999		phenotype	05/13/2019
70	546775		Usp19	0.295	R7037	G1	225.01	Y		9	108496958	I738T	T	C	missense		Het	possibly damaging	0.520	0.143	phenotype	05/13/2019
71	568446		Utrn	0.000	R7037	G1	225.01	Y		10	12826770		T	A	splice site		Het	probably null			phenotype	07/31/2019
[records 1 to 71 of 71]