Incidental Mutation 'R1163:Itsn2'
| ID |
100673 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Itsn2
|
| Ensembl Gene |
ENSMUSG00000020640 |
| Gene Name |
intersectin 2 |
| Synonyms |
Sh3d1B, Sh3p18, Ese2, Eh domain, SH3 domain regulator of endocytosis 2 |
| MMRRC Submission |
039236-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1163 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
12 |
| Chromosomal Location |
4642792-4763952 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 4762009 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 1540
(T1540A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000151900
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000062580]
[ENSMUST00000111154]
[ENSMUST00000219007]
[ENSMUST00000220311]
[ENSMUST00000222363]
[ENSMUST00000220978]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000062580
AA Change: T1540A
PolyPhen 2
Score 0.304 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000052758
Gene: ENSMUSG00000020640
AA Change: T1540A
| Domain | Start | End | E-Value | Type |
|---|
|
EH
|
15 |
109 |
8.44e-41 |
SMART |
|
EFh
|
58 |
86 |
7.18e-3 |
SMART |
|
low complexity region
|
156 |
169 |
N/A |
INTRINSIC |
|
low complexity region
|
215 |
231 |
N/A |
INTRINSIC |
|
EH
|
238 |
333 |
4.06e-43 |
SMART |
|
EFh
|
282 |
310 |
6.16e-2 |
SMART |
|
coiled coil region
|
366 |
462 |
N/A |
INTRINSIC |
|
coiled coil region
|
516 |
556 |
N/A |
INTRINSIC |
|
coiled coil region
|
580 |
715 |
N/A |
INTRINSIC |
|
SH3
|
721 |
778 |
2.65e-21 |
SMART |
|
low complexity region
|
791 |
811 |
N/A |
INTRINSIC |
|
SH3
|
855 |
909 |
8.83e-18 |
SMART |
|
SH3
|
945 |
999 |
9.1e-20 |
SMART |
|
SH3
|
1017 |
1077 |
1.55e-13 |
SMART |
|
SH3
|
1091 |
1146 |
7.22e-23 |
SMART |
|
RhoGEF
|
1174 |
1355 |
1.93e-56 |
SMART |
|
PH
|
1396 |
1507 |
1.16e-9 |
SMART |
|
C2
|
1531 |
1628 |
3.96e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111154
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000218084
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000218211
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000219007
AA Change: T1540A
PolyPhen 2
Score 0.304 (Sensitivity: 0.90; Specificity: 0.89)
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000219182
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000219832
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000220311
AA Change: T1567A
PolyPhen 2
Score 0.069 (Sensitivity: 0.94; Specificity: 0.84)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222363
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000220978
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.3%
- 20x: 92.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. [provided by RefSeq, Jan 2017]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal brain morphology and function and behavior. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700113H08Rik |
T |
A |
10: 86,957,284 (GRCm39) |
Y7N |
probably damaging |
Het |
| 4930579F01Rik |
T |
G |
3: 137,882,271 (GRCm39) |
D18A |
probably damaging |
Het |
| Abca8a |
T |
C |
11: 109,962,356 (GRCm39) |
D499G |
probably benign |
Het |
| Adamts1 |
G |
C |
16: 85,599,525 (GRCm39) |
A25G |
probably benign |
Het |
| Adamts2 |
A |
T |
11: 50,670,541 (GRCm39) |
I552F |
probably damaging |
Het |
| Akap3 |
A |
G |
6: 126,841,750 (GRCm39) |
D123G |
probably damaging |
Het |
| Ankar |
C |
T |
1: 72,727,864 (GRCm39) |
V350I |
possibly damaging |
Het |
| Apob |
A |
G |
12: 8,061,654 (GRCm39) |
T3379A |
probably damaging |
Het |
| Ash1l |
G |
T |
3: 88,942,570 (GRCm39) |
|
probably null |
Het |
| Atp2b1 |
T |
C |
10: 98,815,713 (GRCm39) |
I119T |
possibly damaging |
Het |
| B3gnt2 |
A |
T |
11: 22,786,558 (GRCm39) |
M210K |
probably benign |
Het |
| Bcl11a |
A |
G |
11: 24,115,143 (GRCm39) |
N829D |
probably benign |
Het |
| Btnl4 |
T |
C |
17: 34,689,049 (GRCm39) |
E337G |
possibly damaging |
Het |
| Casr |
A |
T |
16: 36,315,169 (GRCm39) |
V967D |
probably damaging |
Het |
| Cd200 |
A |
T |
16: 45,212,715 (GRCm39) |
V244D |
probably damaging |
Het |
| Cd200r4 |
A |
G |
16: 44,658,383 (GRCm39) |
N256D |
probably benign |
Het |
| Cep68 |
A |
G |
11: 20,190,539 (GRCm39) |
S158P |
probably damaging |
Het |
| Chst10 |
A |
T |
1: 38,910,783 (GRCm39) |
V123D |
probably damaging |
Het |
| Cobll1 |
T |
C |
2: 64,928,623 (GRCm39) |
H938R |
probably damaging |
Het |
| Creld2 |
G |
A |
15: 88,704,834 (GRCm39) |
W103* |
probably null |
Het |
| Dmkn |
T |
G |
7: 30,464,476 (GRCm39) |
C205G |
probably damaging |
Het |
| Dock8 |
A |
G |
19: 25,028,867 (GRCm39) |
I24V |
probably benign |
Het |
| Dpp3 |
C |
T |
19: 4,964,951 (GRCm39) |
W488* |
probably null |
Het |
| Dpp9 |
C |
A |
17: 56,506,426 (GRCm39) |
A365S |
possibly damaging |
Het |
| Egfr |
A |
T |
11: 16,833,546 (GRCm39) |
T605S |
probably benign |
Het |
| Eme2 |
G |
A |
17: 25,111,892 (GRCm39) |
S263F |
probably damaging |
Het |
| Fam83g |
T |
C |
11: 61,594,262 (GRCm39) |
S599P |
probably damaging |
Het |
| Fscn1 |
G |
T |
5: 142,946,598 (GRCm39) |
W132L |
probably damaging |
Het |
| Gbp2b |
A |
G |
3: 142,304,857 (GRCm39) |
T98A |
probably damaging |
Het |
| Gm4922 |
C |
T |
10: 18,659,469 (GRCm39) |
A418T |
possibly damaging |
Het |
| Golgb1 |
G |
T |
16: 36,736,488 (GRCm39) |
V1912L |
possibly damaging |
Het |
| Gon4l |
T |
C |
3: 88,799,842 (GRCm39) |
L829P |
probably damaging |
Het |
| Grm3 |
T |
A |
5: 9,620,738 (GRCm39) |
I169L |
probably benign |
Het |
| Gsdma2 |
A |
G |
11: 98,541,684 (GRCm39) |
D137G |
probably damaging |
Het |
| Hhip |
T |
C |
8: 80,719,105 (GRCm39) |
Y474C |
probably damaging |
Het |
| Hsph1 |
A |
T |
5: 149,554,266 (GRCm39) |
V163E |
probably damaging |
Het |
| Ifi203 |
T |
C |
1: 173,751,703 (GRCm39) |
K373E |
probably damaging |
Het |
| Kdm1b |
T |
C |
13: 47,225,398 (GRCm39) |
V527A |
probably benign |
Het |
| Kdm5d |
G |
A |
Y: 898,029 (GRCm39) |
A22T |
probably benign |
Het |
| Khdrbs1 |
A |
T |
4: 129,619,379 (GRCm39) |
F254Y |
possibly damaging |
Het |
| Kif26a |
T |
C |
12: 112,146,379 (GRCm39) |
F1822L |
probably benign |
Het |
| Krt1 |
C |
A |
15: 101,756,600 (GRCm39) |
E308* |
probably null |
Het |
| Lrrc47 |
T |
A |
4: 154,096,274 (GRCm39) |
M1K |
probably null |
Het |
| Mrgpra4 |
A |
T |
7: 47,631,224 (GRCm39) |
W126R |
probably damaging |
Het |
| Nlrp4e |
G |
A |
7: 23,020,397 (GRCm39) |
V295I |
probably benign |
Het |
| Or1l4b |
A |
T |
2: 37,037,039 (GRCm39) |
T272S |
probably damaging |
Het |
| Or2f1 |
G |
A |
6: 42,721,057 (GRCm39) |
V29I |
probably benign |
Het |
| Or4c10 |
G |
T |
2: 89,760,449 (GRCm39) |
V99F |
possibly damaging |
Het |
| Or5ac19 |
A |
G |
16: 59,089,518 (GRCm39) |
S171P |
probably benign |
Het |
| Or5ac24 |
A |
T |
16: 59,165,425 (GRCm39) |
I213N |
probably damaging |
Het |
| Or5b96 |
T |
A |
19: 12,867,513 (GRCm39) |
T143S |
probably benign |
Het |
| Or6c66 |
A |
G |
10: 129,461,516 (GRCm39) |
V138A |
possibly damaging |
Het |
| Or8h10 |
A |
G |
2: 86,809,020 (GRCm39) |
L40P |
probably damaging |
Het |
| Or8k41 |
A |
T |
2: 86,313,582 (GRCm39) |
F168Y |
probably damaging |
Het |
| Plec |
G |
T |
15: 76,068,038 (GRCm39) |
N1190K |
possibly damaging |
Het |
| Plin1 |
T |
C |
7: 79,379,719 (GRCm39) |
T44A |
probably damaging |
Het |
| Pou3f2 |
TTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTG |
TTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTG |
4: 22,487,697 (GRCm39) |
|
probably benign |
Het |
| Pramel22 |
A |
G |
4: 143,383,204 (GRCm39) |
L5P |
probably damaging |
Het |
| Psg27 |
A |
G |
7: 18,299,234 (GRCm39) |
L29P |
probably damaging |
Het |
| Psmd13 |
C |
A |
7: 140,477,367 (GRCm39) |
T292N |
probably damaging |
Het |
| Rab1b |
A |
T |
19: 5,154,684 (GRCm39) |
Y88* |
probably null |
Het |
| Reln |
T |
A |
5: 22,104,027 (GRCm39) |
I3315L |
probably benign |
Het |
| Rmdn2 |
A |
T |
17: 79,966,880 (GRCm39) |
M257L |
probably benign |
Het |
| Rnd1 |
A |
T |
15: 98,574,435 (GRCm39) |
F47L |
probably damaging |
Het |
| Rnf41 |
G |
A |
10: 128,274,076 (GRCm39) |
V243I |
probably benign |
Het |
| Rnf43 |
C |
G |
11: 87,620,339 (GRCm39) |
S226R |
probably damaging |
Het |
| Scn5a |
A |
T |
9: 119,362,993 (GRCm39) |
D542E |
probably damaging |
Het |
| Sema5b |
A |
T |
16: 35,448,466 (GRCm39) |
I81F |
probably benign |
Het |
| Serinc5 |
G |
A |
13: 92,819,285 (GRCm39) |
C73Y |
probably damaging |
Het |
| Serpina3g |
A |
T |
12: 104,205,551 (GRCm39) |
N97Y |
possibly damaging |
Het |
| Shq1 |
A |
G |
6: 100,614,033 (GRCm39) |
S262P |
probably damaging |
Het |
| Smad4 |
A |
T |
18: 73,781,978 (GRCm39) |
I428N |
probably damaging |
Het |
| Snip1 |
G |
T |
4: 124,966,613 (GRCm39) |
G348W |
probably damaging |
Het |
| Spg11 |
A |
G |
2: 121,901,422 (GRCm39) |
L1506P |
probably damaging |
Het |
| Stard9 |
G |
A |
2: 120,526,694 (GRCm39) |
V984I |
possibly damaging |
Het |
| Svopl |
A |
T |
6: 38,006,635 (GRCm39) |
F121I |
possibly damaging |
Het |
| Tjp1 |
A |
T |
7: 64,972,802 (GRCm39) |
V546E |
probably damaging |
Het |
| Tmem116 |
T |
A |
5: 121,631,819 (GRCm39) |
F110L |
probably damaging |
Het |
| Ttyh2 |
C |
T |
11: 114,601,714 (GRCm39) |
T446M |
probably benign |
Het |
| Tubb1 |
A |
T |
2: 174,299,532 (GRCm39) |
I405L |
probably benign |
Het |
| Uba5 |
A |
T |
9: 103,933,025 (GRCm39) |
F155L |
possibly damaging |
Het |
| Ubd |
C |
T |
17: 37,506,212 (GRCm39) |
H33Y |
probably damaging |
Het |
| Ube3d |
A |
T |
9: 86,322,648 (GRCm39) |
D175E |
probably benign |
Het |
| Usp24 |
A |
G |
4: 106,278,157 (GRCm39) |
Q2293R |
probably benign |
Het |
| Vmn1r175 |
T |
A |
7: 23,507,937 (GRCm39) |
H230L |
probably benign |
Het |
| Vmn1r88 |
A |
G |
7: 12,912,060 (GRCm39) |
I139V |
probably benign |
Het |
| Vmn2r1 |
T |
C |
3: 63,994,046 (GRCm39) |
F131L |
probably benign |
Het |
| Yipf3 |
T |
C |
17: 46,562,155 (GRCm39) |
|
probably null |
Het |
| Zdhhc19 |
A |
G |
16: 32,325,258 (GRCm39) |
K192R |
probably benign |
Het |
| Zfy1 |
G |
A |
Y: 725,611 (GRCm39) |
T718I |
probably damaging |
Het |
|
| Other mutations in Itsn2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00341:Itsn2
|
APN |
12 |
4,708,027 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL00647:Itsn2
|
APN |
12 |
4,663,311 (GRCm39) |
splice site |
probably benign |
|
|
IGL00933:Itsn2
|
APN |
12 |
4,757,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01686:Itsn2
|
APN |
12 |
4,686,693 (GRCm39) |
splice site |
probably benign |
|
|
IGL01873:Itsn2
|
APN |
12 |
4,682,366 (GRCm39) |
splice site |
probably benign |
|
|
IGL02200:Itsn2
|
APN |
12 |
4,686,632 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02280:Itsn2
|
APN |
12 |
4,758,961 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02388:Itsn2
|
APN |
12 |
4,679,557 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02938:Itsn2
|
APN |
12 |
4,747,216 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Gopher
|
UTSW |
12 |
4,756,983 (GRCm39) |
nonsense |
probably null |
|
|
inversus
|
UTSW |
12 |
4,689,670 (GRCm39) |
nonsense |
probably null |
|
|
Liberator
|
UTSW |
12 |
4,716,176 (GRCm39) |
nonsense |
probably null |
|
|
rolled
|
UTSW |
12 |
4,684,792 (GRCm39) |
nonsense |
probably null |
|
|
Stratofortress
|
UTSW |
12 |
4,674,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Underground
|
UTSW |
12 |
4,751,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Vole
|
UTSW |
12 |
4,723,420 (GRCm39) |
nonsense |
probably null |
|
|
R0101:Itsn2
|
UTSW |
12 |
4,683,058 (GRCm39) |
unclassified |
probably benign |
|
|
R0268:Itsn2
|
UTSW |
12 |
4,750,333 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0584:Itsn2
|
UTSW |
12 |
4,747,180 (GRCm39) |
missense |
probably benign |
|
|
R0604:Itsn2
|
UTSW |
12 |
4,708,189 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0639:Itsn2
|
UTSW |
12 |
4,762,556 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0738:Itsn2
|
UTSW |
12 |
4,685,681 (GRCm39) |
missense |
probably benign |
0.17 |
|
R1132:Itsn2
|
UTSW |
12 |
4,708,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1169:Itsn2
|
UTSW |
12 |
4,689,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1258:Itsn2
|
UTSW |
12 |
4,723,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1297:Itsn2
|
UTSW |
12 |
4,750,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1423:Itsn2
|
UTSW |
12 |
4,723,572 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1572:Itsn2
|
UTSW |
12 |
4,700,044 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1601:Itsn2
|
UTSW |
12 |
4,708,452 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1628:Itsn2
|
UTSW |
12 |
4,679,652 (GRCm39) |
missense |
probably benign |
|
|
R1650:Itsn2
|
UTSW |
12 |
4,687,767 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1752:Itsn2
|
UTSW |
12 |
4,761,950 (GRCm39) |
splice site |
probably null |
|
|
R1758:Itsn2
|
UTSW |
12 |
4,708,160 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1942:Itsn2
|
UTSW |
12 |
4,689,670 (GRCm39) |
nonsense |
probably null |
|
|
R1976:Itsn2
|
UTSW |
12 |
4,722,733 (GRCm39) |
splice site |
probably benign |
|
|
R2000:Itsn2
|
UTSW |
12 |
4,716,176 (GRCm39) |
nonsense |
probably null |
|
|
R2060:Itsn2
|
UTSW |
12 |
4,677,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2119:Itsn2
|
UTSW |
12 |
4,757,025 (GRCm39) |
missense |
probably benign |
0.32 |
|
R2168:Itsn2
|
UTSW |
12 |
4,683,044 (GRCm39) |
unclassified |
probably benign |
|
|
R2394:Itsn2
|
UTSW |
12 |
4,757,005 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R2860:Itsn2
|
UTSW |
12 |
4,750,315 (GRCm39) |
splice site |
probably benign |
|
|
R2861:Itsn2
|
UTSW |
12 |
4,750,315 (GRCm39) |
splice site |
probably benign |
|
|
R2900:Itsn2
|
UTSW |
12 |
4,680,713 (GRCm39) |
unclassified |
probably benign |
|
|
R2991:Itsn2
|
UTSW |
12 |
4,708,474 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3087:Itsn2
|
UTSW |
12 |
4,716,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3881:Itsn2
|
UTSW |
12 |
4,684,546 (GRCm39) |
unclassified |
probably benign |
|
|
R4022:Itsn2
|
UTSW |
12 |
4,674,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4332:Itsn2
|
UTSW |
12 |
4,762,611 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4657:Itsn2
|
UTSW |
12 |
4,763,197 (GRCm39) |
makesense |
probably null |
|
|
R4727:Itsn2
|
UTSW |
12 |
4,757,660 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4745:Itsn2
|
UTSW |
12 |
4,711,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4770:Itsn2
|
UTSW |
12 |
4,677,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4905:Itsn2
|
UTSW |
12 |
4,684,583 (GRCm39) |
unclassified |
probably benign |
|
|
R5269:Itsn2
|
UTSW |
12 |
4,683,553 (GRCm39) |
unclassified |
probably benign |
|
|
R5314:Itsn2
|
UTSW |
12 |
4,677,960 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5345:Itsn2
|
UTSW |
12 |
4,722,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5399:Itsn2
|
UTSW |
12 |
4,703,535 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5566:Itsn2
|
UTSW |
12 |
4,676,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5725:Itsn2
|
UTSW |
12 |
4,680,767 (GRCm39) |
unclassified |
probably benign |
|
|
R5773:Itsn2
|
UTSW |
12 |
4,757,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6116:Itsn2
|
UTSW |
12 |
4,679,939 (GRCm39) |
unclassified |
probably benign |
|
|
R6254:Itsn2
|
UTSW |
12 |
4,674,982 (GRCm39) |
splice site |
probably null |
|
|
R6325:Itsn2
|
UTSW |
12 |
4,756,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6361:Itsn2
|
UTSW |
12 |
4,679,655 (GRCm39) |
missense |
probably benign |
0.18 |
|
R6456:Itsn2
|
UTSW |
12 |
4,679,923 (GRCm39) |
unclassified |
probably benign |
|
|
R6494:Itsn2
|
UTSW |
12 |
4,684,792 (GRCm39) |
nonsense |
probably null |
|
|
R6854:Itsn2
|
UTSW |
12 |
4,702,382 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6941:Itsn2
|
UTSW |
12 |
4,679,641 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6961:Itsn2
|
UTSW |
12 |
4,723,420 (GRCm39) |
nonsense |
probably null |
|
|
R7326:Itsn2
|
UTSW |
12 |
4,682,985 (GRCm39) |
missense |
unknown |
|
|
R7387:Itsn2
|
UTSW |
12 |
4,689,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7465:Itsn2
|
UTSW |
12 |
4,756,983 (GRCm39) |
nonsense |
probably null |
|
|
R7471:Itsn2
|
UTSW |
12 |
4,758,198 (GRCm39) |
missense |
probably benign |
0.43 |
|
R7814:Itsn2
|
UTSW |
12 |
4,708,561 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7854:Itsn2
|
UTSW |
12 |
4,751,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7879:Itsn2
|
UTSW |
12 |
4,751,265 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7990:Itsn2
|
UTSW |
12 |
4,685,629 (GRCm39) |
missense |
unknown |
|
|
R8009:Itsn2
|
UTSW |
12 |
4,714,553 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8115:Itsn2
|
UTSW |
12 |
4,723,602 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8143:Itsn2
|
UTSW |
12 |
4,683,003 (GRCm39) |
missense |
unknown |
|
|
R8248:Itsn2
|
UTSW |
12 |
4,712,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8735:Itsn2
|
UTSW |
12 |
4,721,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8748:Itsn2
|
UTSW |
12 |
4,751,337 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9018:Itsn2
|
UTSW |
12 |
4,708,091 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R9386:Itsn2
|
UTSW |
12 |
4,679,730 (GRCm39) |
missense |
unknown |
|
|
R9681:Itsn2
|
UTSW |
12 |
4,683,499 (GRCm39) |
missense |
unknown |
|
|
Z1088:Itsn2
|
UTSW |
12 |
4,762,472 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
|
| Posted On |
2014-01-15 |
Incidental Mutation