Incidental Mutation 'R1168:Adgrb3'
| ID |
101230 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adgrb3
|
| Ensembl Gene |
ENSMUSG00000033569 |
| Gene Name |
adhesion G protein-coupled receptor B3 |
| Synonyms |
Bai3, A830096D10Rik |
| MMRRC Submission |
039241-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.468)
|
| Stock # |
R1168 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
25067476-25829707 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 25826199 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 188
(S188T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000116231
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041838]
[ENSMUST00000135518]
[ENSMUST00000146592]
[ENSMUST00000151309]
|
| AlphaFold |
Q80ZF8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041838
AA Change: S188T
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000035612
Gene: ENSMUSG00000033569
AA Change: S188T
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
7 |
29 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
TSP1
|
294 |
343 |
2.1e-12 |
SMART |
|
TSP1
|
348 |
398 |
7.97e-13 |
SMART |
|
TSP1
|
403 |
453 |
6.28e-11 |
SMART |
|
TSP1
|
458 |
508 |
1.48e-7 |
SMART |
|
HormR
|
510 |
576 |
4.15e-20 |
SMART |
|
Pfam:DUF3497
|
586 |
810 |
1.7e-52 |
PFAM |
|
GPS
|
815 |
868 |
1.24e-21 |
SMART |
|
Pfam:7tm_2
|
874 |
1143 |
2.1e-64 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000135518
AA Change: S188T
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000119804
Gene: ENSMUSG00000033569
AA Change: S188T
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
7 |
29 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
TSP1
|
294 |
343 |
2.1e-12 |
SMART |
|
TSP1
|
348 |
398 |
7.97e-13 |
SMART |
|
TSP1
|
403 |
453 |
6.28e-11 |
SMART |
|
TSP1
|
458 |
508 |
1.48e-7 |
SMART |
|
HormR
|
510 |
576 |
4.15e-20 |
SMART |
|
Pfam:DUF3497
|
586 |
810 |
1.7e-52 |
PFAM |
|
GPS
|
815 |
868 |
1.24e-21 |
SMART |
|
Pfam:7tm_2
|
874 |
1143 |
2.1e-64 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000146592
|
| SMART Domains |
Protein: ENSMUSP00000116759
Gene: ENSMUSG00000033569
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
16 |
N/A |
INTRINSIC |
|
TSP1
|
87 |
136 |
2.1e-12 |
SMART |
|
TSP1
|
141 |
191 |
7.97e-13 |
SMART |
|
TSP1
|
196 |
246 |
6.28e-11 |
SMART |
|
TSP1
|
251 |
301 |
1.48e-7 |
SMART |
|
HormR
|
303 |
369 |
4.15e-20 |
SMART |
|
Pfam:DUF3497
|
379 |
603 |
2.5e-52 |
PFAM |
|
GPS
|
608 |
661 |
1.24e-21 |
SMART |
|
Pfam:7tm_2
|
667 |
903 |
5.4e-66 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000151309
AA Change: S188T
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000116231
Gene: ENSMUSG00000033569
AA Change: S188T
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
7 |
29 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
TSP1
|
294 |
343 |
2.1e-12 |
SMART |
|
TSP1
|
348 |
398 |
7.97e-13 |
SMART |
|
TSP1
|
403 |
453 |
6.28e-11 |
SMART |
|
TSP1
|
458 |
508 |
1.48e-7 |
SMART |
|
HormR
|
510 |
576 |
4.15e-20 |
SMART |
|
Pfam:GAIN
|
589 |
794 |
1.1e-44 |
PFAM |
|
GPS
|
815 |
868 |
1.24e-21 |
SMART |
|
Pfam:7tm_2
|
875 |
1143 |
2.7e-63 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000189254
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194343
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000195754
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.1%
- 10x: 95.2%
- 20x: 88.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a conditional allele activated in Purkinje cells exhibit impaired motor learning with alterned climbing fiber electrophysiology. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110002E22Rik |
T |
C |
3: 138,067,900 (GRCm38) |
V950A |
probably benign |
Het |
| Ahr |
A |
T |
12: 35,504,532 (GRCm38) |
N529K |
possibly damaging |
Het |
| Akr1c21 |
A |
G |
13: 4,583,837 (GRCm38) |
N302D |
probably benign |
Het |
| Aldh8a1 |
T |
A |
10: 21,384,631 (GRCm38) |
|
probably null |
Het |
| Alpk3 |
A |
T |
7: 81,103,357 (GRCm38) |
K1554M |
probably damaging |
Het |
| Arhgef5 |
T |
A |
6: 43,273,396 (GRCm38) |
H360Q |
probably benign |
Het |
| Cacna1a |
A |
G |
8: 84,579,501 (GRCm38) |
I1293V |
probably damaging |
Het |
| Cacna2d4 |
C |
T |
6: 119,307,286 (GRCm38) |
R745W |
probably damaging |
Het |
| Cd200r4 |
T |
A |
16: 44,832,944 (GRCm38) |
W72R |
probably damaging |
Het |
| Ces2e |
A |
T |
8: 104,927,014 (GRCm38) |
D28V |
possibly damaging |
Het |
| Cfap20dc |
T |
C |
14: 8,442,939 (GRCm38) |
N610S |
probably benign |
Het |
| Cfap45 |
T |
C |
1: 172,545,697 (GRCm38) |
Y534H |
probably damaging |
Het |
| Cfap54 |
A |
T |
10: 92,937,920 (GRCm38) |
C87S |
probably damaging |
Het |
| Chmp7 |
C |
T |
14: 69,719,450 (GRCm38) |
M336I |
probably benign |
Het |
| Chrna4 |
T |
A |
2: 181,034,138 (GRCm38) |
M67L |
possibly damaging |
Het |
| Cts7 |
T |
A |
13: 61,353,817 (GRCm38) |
N290Y |
probably damaging |
Het |
| Enpp6 |
A |
T |
8: 47,030,454 (GRCm38) |
M94L |
probably damaging |
Het |
| Fam83d |
C |
T |
2: 158,768,523 (GRCm38) |
A137V |
probably benign |
Het |
| Foxd2 |
C |
T |
4: 114,907,678 (GRCm38) |
A382T |
possibly damaging |
Het |
| Galnt11 |
T |
G |
5: 25,250,246 (GRCm38) |
S193R |
probably damaging |
Het |
| Gapvd1 |
A |
T |
2: 34,704,469 (GRCm38) |
D856E |
probably damaging |
Het |
| Gclm |
T |
A |
3: 122,262,688 (GRCm38) |
H86Q |
possibly damaging |
Het |
| Gipc2 |
T |
C |
3: 152,107,997 (GRCm38) |
T220A |
probably benign |
Het |
| Gm12185 |
G |
T |
11: 48,915,355 (GRCm38) |
N336K |
possibly damaging |
Het |
| Gm5431 |
A |
T |
11: 48,895,364 (GRCm38) |
S61R |
probably benign |
Het |
| Gorasp2 |
C |
T |
2: 70,688,400 (GRCm38) |
P260S |
probably damaging |
Het |
| H2-M10.6 |
A |
G |
17: 36,813,160 (GRCm38) |
Q172R |
probably benign |
Het |
| Ibsp |
A |
G |
5: 104,302,152 (GRCm38) |
I6V |
probably damaging |
Het |
| Iqsec1 |
T |
C |
6: 90,689,676 (GRCm38) |
Y593C |
probably damaging |
Het |
| Irag1 |
T |
C |
7: 110,895,931 (GRCm38) |
K429R |
probably damaging |
Het |
| Itln1 |
G |
T |
1: 171,531,551 (GRCm38) |
Y61* |
probably null |
Het |
| Kif21a |
G |
A |
15: 90,993,753 (GRCm38) |
T284I |
probably damaging |
Het |
| Kif3a |
G |
A |
11: 53,598,312 (GRCm38) |
G621R |
probably damaging |
Het |
| Klb |
A |
G |
5: 65,378,974 (GRCm38) |
Y549C |
probably damaging |
Het |
| Lman1l |
G |
A |
9: 57,608,312 (GRCm38) |
R427C |
probably benign |
Het |
| Lrrc37 |
T |
C |
11: 103,618,950 (GRCm38) |
|
probably benign |
Het |
| Map4 |
T |
C |
9: 110,034,964 (GRCm38) |
V419A |
probably benign |
Het |
| Mastl |
A |
T |
2: 23,133,132 (GRCm38) |
D526E |
probably benign |
Het |
| Mtif2 |
A |
G |
11: 29,536,914 (GRCm38) |
D308G |
probably benign |
Het |
| Ncald |
A |
G |
15: 37,397,334 (GRCm38) |
F34S |
probably damaging |
Het |
| Ndc1 |
A |
G |
4: 107,395,812 (GRCm38) |
T593A |
probably benign |
Het |
| Ndst3 |
C |
T |
3: 123,606,968 (GRCm38) |
V15I |
probably benign |
Het |
| Nup214 |
A |
G |
2: 32,025,301 (GRCm38) |
N1166D |
probably benign |
Het |
| Or1a1 |
A |
G |
11: 74,196,421 (GRCm38) |
H306R |
probably benign |
Het |
| Or2ad1 |
A |
G |
13: 21,142,617 (GRCm38) |
S147P |
probably benign |
Het |
| Or4a68 |
G |
A |
2: 89,439,869 (GRCm38) |
Q137* |
probably null |
Het |
| Or5m8 |
A |
T |
2: 85,992,684 (GRCm38) |
Y289F |
probably damaging |
Het |
| Pcdhb8 |
T |
C |
18: 37,356,727 (GRCm38) |
I486T |
probably benign |
Het |
| Pdzrn4 |
A |
T |
15: 92,770,271 (GRCm38) |
Y768F |
probably benign |
Het |
| Pgf |
A |
G |
12: 85,171,767 (GRCm38) |
S70P |
probably benign |
Het |
| Plcl2 |
G |
A |
17: 50,607,072 (GRCm38) |
A370T |
possibly damaging |
Het |
| Pnkp |
T |
A |
7: 44,862,537 (GRCm38) |
W115R |
probably benign |
Het |
| Ppp1r16a |
C |
T |
15: 76,693,669 (GRCm38) |
Q328* |
probably null |
Het |
| Prag1 |
A |
G |
8: 36,146,645 (GRCm38) |
E1117G |
probably damaging |
Het |
| Prr12 |
T |
A |
7: 45,029,047 (GRCm38) |
Q1919L |
unknown |
Het |
| Ret |
G |
T |
6: 118,173,558 (GRCm38) |
H666N |
possibly damaging |
Het |
| Rfwd3 |
C |
T |
8: 111,288,242 (GRCm38) |
R326Q |
probably damaging |
Het |
| Robo2 |
C |
T |
16: 73,948,296 (GRCm38) |
G864S |
probably damaging |
Het |
| Rpa2 |
T |
G |
4: 132,771,860 (GRCm38) |
I80S |
probably damaging |
Het |
| Ryk |
A |
T |
9: 102,898,475 (GRCm38) |
D428V |
probably damaging |
Het |
| Slc29a1 |
A |
T |
17: 45,590,278 (GRCm38) |
N30K |
probably damaging |
Het |
| Stbd1 |
A |
G |
5: 92,604,936 (GRCm38) |
N95S |
probably benign |
Het |
| Tbc1d22a |
A |
G |
15: 86,292,134 (GRCm38) |
E212G |
probably benign |
Het |
| Tex14 |
A |
G |
11: 87,536,742 (GRCm38) |
T7A |
probably benign |
Het |
| Tmc8 |
T |
C |
11: 117,792,563 (GRCm38) |
V648A |
possibly damaging |
Het |
| Tmem132b |
G |
T |
5: 125,787,019 (GRCm38) |
V730F |
probably damaging |
Het |
| Tmub2 |
G |
A |
11: 102,287,370 (GRCm38) |
G33D |
possibly damaging |
Het |
| Trak1 |
G |
A |
9: 121,440,679 (GRCm38) |
D124N |
probably damaging |
Het |
| Ttc28 |
A |
T |
5: 111,231,111 (GRCm38) |
Y1154F |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,909,369 (GRCm38) |
T3609A |
probably benign |
Het |
| Tulp2 |
A |
G |
7: 45,517,842 (GRCm38) |
T99A |
probably benign |
Het |
| Ugt2a2 |
A |
T |
5: 87,465,568 (GRCm38) |
|
probably null |
Het |
| Ush2a |
G |
A |
1: 188,678,411 (GRCm38) |
V2419I |
probably benign |
Het |
| Vill |
C |
A |
9: 119,070,321 (GRCm38) |
P343Q |
probably damaging |
Het |
| Vmn2r66 |
T |
A |
7: 85,006,854 (GRCm38) |
H318L |
possibly damaging |
Het |
| Wdr3 |
A |
C |
3: 100,142,219 (GRCm38) |
N800K |
probably benign |
Het |
| Wdr93 |
A |
G |
7: 79,749,174 (GRCm38) |
K19E |
probably damaging |
Het |
| Wrn |
A |
G |
8: 33,316,408 (GRCm38) |
S333P |
probably damaging |
Het |
| Zfp418 |
T |
C |
7: 7,182,501 (GRCm38) |
S488P |
possibly damaging |
Het |
| Zfp804a |
A |
G |
2: 82,256,697 (GRCm38) |
E290G |
probably benign |
Het |
|
| Other mutations in Adgrb3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00164:Adgrb3
|
APN |
1 |
25,228,500 (GRCm38) |
missense |
probably benign |
0.09 |
|
IGL00507:Adgrb3
|
APN |
1 |
25,074,715 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL00828:Adgrb3
|
APN |
1 |
25,488,119 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
IGL01285:Adgrb3
|
APN |
1 |
25,093,787 (GRCm38) |
missense |
probably benign |
0.32 |
|
IGL01309:Adgrb3
|
APN |
1 |
25,112,271 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
IGL01540:Adgrb3
|
APN |
1 |
25,112,171 (GRCm38) |
splice site |
probably null |
|
|
IGL01608:Adgrb3
|
APN |
1 |
25,553,774 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01638:Adgrb3
|
APN |
1 |
25,559,751 (GRCm38) |
splice site |
probably benign |
|
|
IGL01657:Adgrb3
|
APN |
1 |
25,826,493 (GRCm38) |
missense |
probably benign |
0.03 |
|
IGL01666:Adgrb3
|
APN |
1 |
25,460,751 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL01712:Adgrb3
|
APN |
1 |
25,826,279 (GRCm38) |
missense |
probably benign |
|
|
IGL01767:Adgrb3
|
APN |
1 |
25,559,814 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01987:Adgrb3
|
APN |
1 |
25,101,431 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02201:Adgrb3
|
APN |
1 |
25,420,550 (GRCm38) |
splice site |
probably benign |
|
|
IGL02584:Adgrb3
|
APN |
1 |
25,504,984 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02685:Adgrb3
|
APN |
1 |
25,084,242 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02886:Adgrb3
|
APN |
1 |
25,504,910 (GRCm38) |
splice site |
probably null |
|
|
IGL02929:Adgrb3
|
APN |
1 |
25,553,824 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03153:Adgrb3
|
APN |
1 |
25,531,897 (GRCm38) |
nonsense |
probably null |
|
|
IGL03165:Adgrb3
|
APN |
1 |
25,094,394 (GRCm38) |
missense |
probably benign |
0.05 |
|
IGL03227:Adgrb3
|
APN |
1 |
25,547,475 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03392:Adgrb3
|
APN |
1 |
25,504,448 (GRCm38) |
missense |
probably damaging |
0.99 |
|
schwach
|
UTSW |
1 |
25,111,691 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0007:Adgrb3
|
UTSW |
1 |
25,111,691 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0048:Adgrb3
|
UTSW |
1 |
25,101,482 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0048:Adgrb3
|
UTSW |
1 |
25,101,482 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0322:Adgrb3
|
UTSW |
1 |
25,221,748 (GRCm38) |
splice site |
probably benign |
|
|
R0442:Adgrb3
|
UTSW |
1 |
25,396,470 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R0563:Adgrb3
|
UTSW |
1 |
25,547,554 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1252:Adgrb3
|
UTSW |
1 |
25,128,828 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1264:Adgrb3
|
UTSW |
1 |
25,559,850 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1543:Adgrb3
|
UTSW |
1 |
25,488,088 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1577:Adgrb3
|
UTSW |
1 |
25,094,183 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R1581:Adgrb3
|
UTSW |
1 |
25,094,072 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R1583:Adgrb3
|
UTSW |
1 |
25,226,831 (GRCm38) |
splice site |
probably null |
|
|
R1653:Adgrb3
|
UTSW |
1 |
25,101,503 (GRCm38) |
missense |
probably benign |
0.09 |
|
R1725:Adgrb3
|
UTSW |
1 |
25,826,300 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1792:Adgrb3
|
UTSW |
1 |
25,228,471 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1827:Adgrb3
|
UTSW |
1 |
25,532,577 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1838:Adgrb3
|
UTSW |
1 |
25,084,270 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1869:Adgrb3
|
UTSW |
1 |
25,826,438 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R1971:Adgrb3
|
UTSW |
1 |
25,547,444 (GRCm38) |
missense |
probably benign |
0.02 |
|
R2005:Adgrb3
|
UTSW |
1 |
25,111,718 (GRCm38) |
missense |
probably benign |
0.25 |
|
R2134:Adgrb3
|
UTSW |
1 |
25,093,957 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2142:Adgrb3
|
UTSW |
1 |
25,068,209 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2268:Adgrb3
|
UTSW |
1 |
25,111,817 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R3740:Adgrb3
|
UTSW |
1 |
25,826,454 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3877:Adgrb3
|
UTSW |
1 |
25,111,825 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4120:Adgrb3
|
UTSW |
1 |
25,094,307 (GRCm38) |
nonsense |
probably null |
|
|
R4344:Adgrb3
|
UTSW |
1 |
25,826,748 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R4363:Adgrb3
|
UTSW |
1 |
25,112,222 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4438:Adgrb3
|
UTSW |
1 |
25,831,027 (GRCm38) |
unclassified |
probably benign |
|
|
R4465:Adgrb3
|
UTSW |
1 |
25,094,366 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4480:Adgrb3
|
UTSW |
1 |
25,111,748 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4554:Adgrb3
|
UTSW |
1 |
25,084,279 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4557:Adgrb3
|
UTSW |
1 |
25,084,279 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4622:Adgrb3
|
UTSW |
1 |
25,826,488 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4713:Adgrb3
|
UTSW |
1 |
25,547,532 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4772:Adgrb3
|
UTSW |
1 |
25,531,875 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4890:Adgrb3
|
UTSW |
1 |
25,221,827 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5045:Adgrb3
|
UTSW |
1 |
25,074,779 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5061:Adgrb3
|
UTSW |
1 |
25,068,128 (GRCm38) |
utr 3 prime |
probably benign |
|
|
R5097:Adgrb3
|
UTSW |
1 |
25,826,084 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5227:Adgrb3
|
UTSW |
1 |
25,093,952 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R5241:Adgrb3
|
UTSW |
1 |
25,111,790 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R5328:Adgrb3
|
UTSW |
1 |
25,094,275 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R5372:Adgrb3
|
UTSW |
1 |
25,128,859 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5703:Adgrb3
|
UTSW |
1 |
25,420,559 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5747:Adgrb3
|
UTSW |
1 |
25,826,562 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5998:Adgrb3
|
UTSW |
1 |
25,431,501 (GRCm38) |
splice site |
probably null |
|
|
R6006:Adgrb3
|
UTSW |
1 |
25,826,531 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R6077:Adgrb3
|
UTSW |
1 |
25,094,000 (GRCm38) |
nonsense |
probably null |
|
|
R6183:Adgrb3
|
UTSW |
1 |
25,094,370 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6190:Adgrb3
|
UTSW |
1 |
25,420,647 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6249:Adgrb3
|
UTSW |
1 |
25,432,558 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6310:Adgrb3
|
UTSW |
1 |
25,111,718 (GRCm38) |
missense |
probably benign |
0.13 |
|
R6450:Adgrb3
|
UTSW |
1 |
25,420,602 (GRCm38) |
missense |
probably benign |
|
|
R6678:Adgrb3
|
UTSW |
1 |
25,460,810 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R6679:Adgrb3
|
UTSW |
1 |
25,131,296 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6685:Adgrb3
|
UTSW |
1 |
25,111,736 (GRCm38) |
nonsense |
probably null |
|
|
R6730:Adgrb3
|
UTSW |
1 |
25,094,294 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6805:Adgrb3
|
UTSW |
1 |
25,826,172 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R6847:Adgrb3
|
UTSW |
1 |
25,093,922 (GRCm38) |
missense |
probably benign |
0.03 |
|
R6929:Adgrb3
|
UTSW |
1 |
25,111,771 (GRCm38) |
nonsense |
probably null |
|
|
R6953:Adgrb3
|
UTSW |
1 |
25,826,511 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7062:Adgrb3
|
UTSW |
1 |
25,826,085 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R7244:Adgrb3
|
UTSW |
1 |
25,131,269 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7292:Adgrb3
|
UTSW |
1 |
25,531,876 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7325:Adgrb3
|
UTSW |
1 |
25,532,630 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7378:Adgrb3
|
UTSW |
1 |
25,531,919 (GRCm38) |
nonsense |
probably null |
|
|
R7489:Adgrb3
|
UTSW |
1 |
25,547,505 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7615:Adgrb3
|
UTSW |
1 |
25,098,897 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7623:Adgrb3
|
UTSW |
1 |
25,547,548 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7787:Adgrb3
|
UTSW |
1 |
25,432,544 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7837:Adgrb3
|
UTSW |
1 |
25,128,834 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8064:Adgrb3
|
UTSW |
1 |
25,420,556 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8152:Adgrb3
|
UTSW |
1 |
25,221,757 (GRCm38) |
splice site |
probably null |
|
|
R8161:Adgrb3
|
UTSW |
1 |
25,093,922 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8225:Adgrb3
|
UTSW |
1 |
25,826,516 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8417:Adgrb3
|
UTSW |
1 |
25,488,053 (GRCm38) |
missense |
probably benign |
0.21 |
|
R8694:Adgrb3
|
UTSW |
1 |
25,826,391 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8742:Adgrb3
|
UTSW |
1 |
25,226,754 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8886:Adgrb3
|
UTSW |
1 |
25,111,847 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8941:Adgrb3
|
UTSW |
1 |
25,094,154 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8958:Adgrb3
|
UTSW |
1 |
25,826,109 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R8979:Adgrb3
|
UTSW |
1 |
25,488,034 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9064:Adgrb3
|
UTSW |
1 |
25,531,884 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R9252:Adgrb3
|
UTSW |
1 |
25,826,415 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9401:Adgrb3
|
UTSW |
1 |
25,553,702 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9739:Adgrb3
|
UTSW |
1 |
25,553,768 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Adgrb3
|
UTSW |
1 |
25,131,271 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Adgrb3
|
UTSW |
1 |
25,093,914 (GRCm38) |
missense |
probably benign |
0.37 |
|
| Predicted Primers |
|
| Posted On |
2014-01-15 |
Incidental Mutation