Incidental Mutation 'R1184:Chd6'
| ID |
101877 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Chd6
|
| Ensembl Gene |
ENSMUSG00000057133 |
| Gene Name |
chromodomain helicase DNA binding protein 6 |
| Synonyms |
5430439G14Rik, 6330406J24Rik |
| MMRRC Submission |
039256-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.745)
|
| Stock # |
R1184 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
160788898-160950995 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to C
at 160872722 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Arginine
at position 286
(P286R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000042291
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039782]
[ENSMUST00000130265]
[ENSMUST00000134178]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000039782
AA Change: P286R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000042291
Gene: ENSMUSG00000057133
AA Change: P286R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
86 |
106 |
N/A |
INTRINSIC |
|
low complexity region
|
113 |
143 |
N/A |
INTRINSIC |
|
low complexity region
|
214 |
229 |
N/A |
INTRINSIC |
|
CHROMO
|
289 |
355 |
1.35e-4 |
SMART |
|
CHROMO
|
372 |
430 |
3.48e-7 |
SMART |
|
DEXDc
|
456 |
658 |
1.73e-39 |
SMART |
|
HELICc
|
812 |
896 |
3.84e-23 |
SMART |
|
low complexity region
|
1080 |
1094 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1108 |
1153 |
4e-23 |
BLAST |
|
SANT
|
1445 |
1504 |
1.51e0 |
SMART |
|
low complexity region
|
1866 |
1875 |
N/A |
INTRINSIC |
|
low complexity region
|
2048 |
2057 |
N/A |
INTRINSIC |
|
low complexity region
|
2130 |
2140 |
N/A |
INTRINSIC |
|
low complexity region
|
2277 |
2290 |
N/A |
INTRINSIC |
|
low complexity region
|
2333 |
2349 |
N/A |
INTRINSIC |
|
low complexity region
|
2437 |
2446 |
N/A |
INTRINSIC |
|
low complexity region
|
2539 |
2563 |
N/A |
INTRINSIC |
|
low complexity region
|
2652 |
2659 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000125179
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000130265
AA Change: P166R
PolyPhen 2
Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000117075
Gene: ENSMUSG00000057133
AA Change: P166R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
1 |
23 |
N/A |
INTRINSIC |
|
Blast:CHROMO
|
26 |
210 |
4e-80 |
BLAST |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000134178
AA Change: P285R
PolyPhen 2
Score 0.759 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000123240
Gene: ENSMUSG00000057133
AA Change: P285R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
86 |
106 |
N/A |
INTRINSIC |
|
low complexity region
|
113 |
143 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
228 |
N/A |
INTRINSIC |
|
CHROMO
|
288 |
354 |
1.35e-4 |
SMART |
|
CHROMO
|
371 |
429 |
3.48e-7 |
SMART |
|
DEXDc
|
455 |
657 |
1.73e-39 |
SMART |
|
HELICc
|
811 |
895 |
3.84e-23 |
SMART |
|
low complexity region
|
1079 |
1093 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1107 |
1152 |
4e-23 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000138078
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000155066
|
| Meta Mutation Damage Score |
0.1112 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.2%
- 10x: 95.9%
- 20x: 91.5%
|
| Validation Efficiency |
100% (83/83) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the chromodomain/helicase/DNA-binding domain family of chromatin remodeling enzymes. This protein has been found to be specifically involved in transcription initiation and elongation. Homozygous knockout mice exhibit impaired motor coordination. A pseudogene has been identified on chromosome 8. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014]
PHENOTYPE: Homozygous null mice display impaired coordination that is not due to muscle weakness or bradykinesia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700003E16Rik |
A |
G |
6: 83,137,894 (GRCm39) |
R7G |
probably damaging |
Het |
| Ahdc1 |
T |
A |
4: 132,792,707 (GRCm39) |
M1316K |
probably benign |
Het |
| Alkal1 |
A |
G |
1: 6,459,712 (GRCm39) |
Y96C |
probably damaging |
Het |
| Anxa2r1 |
A |
T |
13: 120,496,667 (GRCm39) |
N67K |
probably benign |
Het |
| Arhgap17 |
T |
C |
7: 122,913,913 (GRCm39) |
Y199C |
probably damaging |
Het |
| Bmp2 |
T |
C |
2: 133,403,388 (GRCm39) |
V313A |
probably damaging |
Het |
| Cacna1b |
C |
T |
2: 24,577,757 (GRCm39) |
|
probably null |
Het |
| Cars1 |
T |
C |
7: 143,140,876 (GRCm39) |
T141A |
probably damaging |
Het |
| Ccdc57 |
A |
G |
11: 120,764,637 (GRCm39) |
|
probably benign |
Het |
| Cenpe |
T |
C |
3: 134,970,183 (GRCm39) |
|
probably null |
Het |
| Chadl |
T |
C |
15: 81,577,258 (GRCm39) |
S198G |
probably benign |
Het |
| Clec4a4 |
G |
T |
6: 122,989,671 (GRCm39) |
W104L |
probably benign |
Het |
| Coq4 |
G |
A |
2: 29,678,346 (GRCm39) |
|
probably benign |
Het |
| Cplane1 |
G |
T |
15: 8,245,971 (GRCm39) |
V1448L |
probably benign |
Het |
| Crtc2 |
T |
A |
3: 90,169,940 (GRCm39) |
Y445* |
probably null |
Het |
| Dapk1 |
A |
T |
13: 60,844,112 (GRCm39) |
I44F |
probably damaging |
Het |
| Dcbld2 |
T |
A |
16: 58,270,204 (GRCm39) |
|
probably null |
Het |
| Dcun1d4 |
T |
C |
5: 73,668,455 (GRCm39) |
|
probably benign |
Het |
| Depdc7 |
A |
T |
2: 104,560,523 (GRCm39) |
|
probably benign |
Het |
| Dna2 |
A |
G |
10: 62,794,977 (GRCm39) |
D416G |
probably benign |
Het |
| Dnah2 |
A |
T |
11: 69,390,016 (GRCm39) |
I743N |
probably damaging |
Het |
| Dnah9 |
A |
G |
11: 65,975,438 (GRCm39) |
|
probably null |
Het |
| Dock3 |
A |
G |
9: 106,846,999 (GRCm39) |
S877P |
probably damaging |
Het |
| Eif3l |
T |
A |
15: 78,959,966 (GRCm39) |
|
probably null |
Het |
| Epha5 |
A |
T |
5: 84,219,134 (GRCm39) |
|
probably null |
Het |
| Ffar3 |
T |
A |
7: 30,554,529 (GRCm39) |
N264Y |
probably damaging |
Het |
| Fyb1 |
A |
T |
15: 6,668,381 (GRCm39) |
I525F |
probably damaging |
Het |
| Fyco1 |
A |
G |
9: 123,648,218 (GRCm39) |
F1239L |
probably damaging |
Het |
| Gcdh |
T |
C |
8: 85,620,071 (GRCm39) |
|
probably benign |
Het |
| Gk5 |
T |
C |
9: 96,032,473 (GRCm39) |
|
probably benign |
Het |
| Grm1 |
A |
G |
10: 10,595,778 (GRCm39) |
Y617H |
probably benign |
Het |
| Gvin-ps3 |
A |
G |
7: 105,683,159 (GRCm39) |
V32A |
probably benign |
Het |
| Hhipl2 |
A |
T |
1: 183,206,042 (GRCm39) |
I131L |
probably damaging |
Het |
| Larp4b |
T |
C |
13: 9,216,345 (GRCm39) |
|
probably benign |
Het |
| Lrig2 |
T |
A |
3: 104,398,227 (GRCm39) |
I301F |
possibly damaging |
Het |
| Man2a2 |
A |
T |
7: 80,012,713 (GRCm39) |
I600N |
possibly damaging |
Het |
| Mylk2 |
G |
C |
2: 152,755,661 (GRCm39) |
|
probably null |
Het |
| Myo6 |
C |
T |
9: 80,193,664 (GRCm39) |
Q870* |
probably null |
Het |
| Napg |
T |
G |
18: 63,127,409 (GRCm39) |
H204Q |
probably benign |
Het |
| Neb |
G |
A |
2: 52,153,959 (GRCm39) |
T2384M |
probably damaging |
Het |
| Nek10 |
A |
G |
14: 14,931,325 (GRCm38) |
|
probably benign |
Het |
| Or11h23 |
A |
C |
14: 50,948,071 (GRCm39) |
T95P |
probably benign |
Het |
| Or4c111 |
A |
G |
2: 88,844,057 (GRCm39) |
M117T |
probably damaging |
Het |
| Or5an6 |
T |
C |
19: 12,372,221 (GRCm39) |
V198A |
probably benign |
Het |
| Or5b108 |
T |
G |
19: 13,168,739 (GRCm39) |
L236R |
probably damaging |
Het |
| Pclo |
A |
G |
5: 14,572,276 (GRCm39) |
T554A |
unknown |
Het |
| Perm1 |
C |
A |
4: 156,301,771 (GRCm39) |
T105K |
probably damaging |
Het |
| Pik3r1 |
T |
C |
13: 101,822,866 (GRCm39) |
|
probably null |
Het |
| Pld5 |
A |
G |
1: 175,872,462 (GRCm39) |
I225T |
probably damaging |
Het |
| Plxnc1 |
T |
C |
10: 94,667,195 (GRCm39) |
|
probably benign |
Het |
| Ptpn12 |
A |
C |
5: 21,203,354 (GRCm39) |
S475A |
possibly damaging |
Het |
| Ptprt |
A |
G |
2: 161,769,692 (GRCm39) |
V391A |
possibly damaging |
Het |
| Rac2 |
T |
G |
15: 78,450,145 (GRCm39) |
D65A |
possibly damaging |
Het |
| Rgl3 |
A |
G |
9: 21,888,676 (GRCm39) |
|
probably null |
Het |
| Rif1 |
GCCACCA |
GCCA |
2: 52,000,336 (GRCm39) |
|
probably benign |
Het |
| Sebox |
A |
T |
11: 78,394,675 (GRCm39) |
T47S |
probably damaging |
Het |
| Sema4b |
A |
G |
7: 79,874,388 (GRCm39) |
T593A |
probably benign |
Het |
| Serpina3a |
C |
T |
12: 104,082,787 (GRCm39) |
Q187* |
probably null |
Het |
| Serpinb1a |
T |
C |
13: 33,027,199 (GRCm39) |
K248E |
probably benign |
Het |
| Serpinb9e |
A |
C |
13: 33,443,757 (GRCm39) |
E259A |
probably benign |
Het |
| Slc30a3 |
T |
A |
5: 31,247,510 (GRCm39) |
H44L |
probably damaging |
Het |
| Smarca2 |
T |
C |
19: 26,748,333 (GRCm39) |
|
probably benign |
Het |
| Snrnp200 |
T |
A |
2: 127,078,737 (GRCm39) |
C1801S |
probably damaging |
Het |
| Soat1 |
G |
A |
1: 156,269,944 (GRCm39) |
|
probably null |
Het |
| Spink6 |
T |
C |
18: 44,204,605 (GRCm39) |
|
probably benign |
Het |
| Spta1 |
G |
A |
1: 174,012,256 (GRCm39) |
R354H |
probably damaging |
Het |
| Tbck |
T |
A |
3: 132,543,733 (GRCm39) |
H861Q |
probably benign |
Het |
| Tgfbrap1 |
G |
A |
1: 43,088,856 (GRCm39) |
T849M |
possibly damaging |
Het |
| Tnrc6a |
A |
G |
7: 122,769,563 (GRCm39) |
N451S |
possibly damaging |
Het |
| Trim36 |
T |
C |
18: 46,329,318 (GRCm39) |
T41A |
probably damaging |
Het |
| Trmt112 |
C |
A |
19: 6,887,721 (GRCm39) |
|
probably benign |
Het |
| Trpc4ap |
A |
G |
2: 155,486,990 (GRCm39) |
|
probably benign |
Het |
| Ttll7 |
C |
T |
3: 146,645,746 (GRCm39) |
P535S |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,691,776 (GRCm39) |
|
probably benign |
Het |
| Txndc11 |
C |
T |
16: 10,946,364 (GRCm39) |
R149Q |
probably benign |
Het |
| Ubr4 |
C |
T |
4: 139,164,509 (GRCm39) |
|
probably benign |
Het |
| Usp30 |
G |
A |
5: 114,241,888 (GRCm39) |
|
probably null |
Het |
| Vmn1r195 |
A |
G |
13: 22,463,181 (GRCm39) |
Y217C |
probably damaging |
Het |
| Vps33b |
T |
A |
7: 79,932,234 (GRCm39) |
D135E |
probably benign |
Het |
| Vrk2 |
A |
G |
11: 26,433,331 (GRCm39) |
|
probably benign |
Het |
| Wdr81 |
G |
T |
11: 75,343,809 (GRCm39) |
P486Q |
probably damaging |
Het |
| Zfp788 |
T |
C |
7: 41,297,750 (GRCm39) |
Y129H |
probably damaging |
Het |
|
| Other mutations in Chd6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00837:Chd6
|
APN |
2 |
160,883,999 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00899:Chd6
|
APN |
2 |
160,871,218 (GRCm39) |
splice site |
probably benign |
|
|
IGL01104:Chd6
|
APN |
2 |
160,803,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01295:Chd6
|
APN |
2 |
160,830,290 (GRCm39) |
splice site |
probably benign |
|
|
IGL01717:Chd6
|
APN |
2 |
160,807,179 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL01795:Chd6
|
APN |
2 |
160,803,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01814:Chd6
|
APN |
2 |
160,901,849 (GRCm39) |
missense |
probably benign |
0.25 |
|
IGL02016:Chd6
|
APN |
2 |
160,825,598 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02104:Chd6
|
APN |
2 |
160,819,432 (GRCm39) |
missense |
probably benign |
|
|
IGL02158:Chd6
|
APN |
2 |
160,868,212 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL02313:Chd6
|
APN |
2 |
160,807,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02472:Chd6
|
APN |
2 |
160,826,372 (GRCm39) |
splice site |
probably benign |
|
|
IGL02522:Chd6
|
APN |
2 |
160,807,716 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02626:Chd6
|
APN |
2 |
160,881,270 (GRCm39) |
splice site |
probably benign |
|
|
IGL02727:Chd6
|
APN |
2 |
160,811,383 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02738:Chd6
|
APN |
2 |
160,807,618 (GRCm39) |
missense |
probably benign |
0.45 |
|
IGL02743:Chd6
|
APN |
2 |
160,802,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02800:Chd6
|
APN |
2 |
160,826,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02811:Chd6
|
APN |
2 |
160,832,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02850:Chd6
|
APN |
2 |
160,861,536 (GRCm39) |
nonsense |
probably null |
|
|
IGL02979:Chd6
|
APN |
2 |
160,808,090 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02993:Chd6
|
APN |
2 |
160,894,304 (GRCm39) |
splice site |
probably benign |
|
|
IGL03277:Chd6
|
APN |
2 |
160,824,981 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL03346:Chd6
|
APN |
2 |
160,802,282 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03357:Chd6
|
APN |
2 |
160,859,936 (GRCm39) |
splice site |
probably benign |
|
|
IGL03134:Chd6
|
UTSW |
2 |
160,807,403 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R0106:Chd6
|
UTSW |
2 |
160,809,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0106:Chd6
|
UTSW |
2 |
160,809,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0212:Chd6
|
UTSW |
2 |
160,894,767 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0363:Chd6
|
UTSW |
2 |
160,856,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0399:Chd6
|
UTSW |
2 |
160,894,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0511:Chd6
|
UTSW |
2 |
160,834,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0771:Chd6
|
UTSW |
2 |
160,861,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Chd6
|
UTSW |
2 |
160,832,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Chd6
|
UTSW |
2 |
160,832,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1277:Chd6
|
UTSW |
2 |
160,809,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1396:Chd6
|
UTSW |
2 |
160,825,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1647:Chd6
|
UTSW |
2 |
160,883,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1648:Chd6
|
UTSW |
2 |
160,883,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1745:Chd6
|
UTSW |
2 |
160,823,587 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1766:Chd6
|
UTSW |
2 |
160,808,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1871:Chd6
|
UTSW |
2 |
160,832,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1928:Chd6
|
UTSW |
2 |
160,809,920 (GRCm39) |
splice site |
probably benign |
|
|
R1973:Chd6
|
UTSW |
2 |
160,808,307 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2200:Chd6
|
UTSW |
2 |
160,825,673 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2340:Chd6
|
UTSW |
2 |
160,807,679 (GRCm39) |
frame shift |
probably null |
|
|
R2341:Chd6
|
UTSW |
2 |
160,807,679 (GRCm39) |
frame shift |
probably null |
|
|
R2519:Chd6
|
UTSW |
2 |
160,871,796 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R2919:Chd6
|
UTSW |
2 |
160,809,800 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3025:Chd6
|
UTSW |
2 |
160,808,472 (GRCm39) |
small deletion |
probably benign |
|
|
R3426:Chd6
|
UTSW |
2 |
160,832,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3427:Chd6
|
UTSW |
2 |
160,832,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4042:Chd6
|
UTSW |
2 |
160,830,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4273:Chd6
|
UTSW |
2 |
160,803,211 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4360:Chd6
|
UTSW |
2 |
160,791,776 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R4399:Chd6
|
UTSW |
2 |
160,807,238 (GRCm39) |
missense |
probably benign |
|
|
R4458:Chd6
|
UTSW |
2 |
160,871,796 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4583:Chd6
|
UTSW |
2 |
160,856,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4625:Chd6
|
UTSW |
2 |
160,811,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4740:Chd6
|
UTSW |
2 |
160,812,103 (GRCm39) |
missense |
probably benign |
|
|
R4765:Chd6
|
UTSW |
2 |
160,808,164 (GRCm39) |
nonsense |
probably null |
|
|
R4779:Chd6
|
UTSW |
2 |
160,791,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4877:Chd6
|
UTSW |
2 |
160,871,219 (GRCm39) |
splice site |
probably benign |
|
|
R5068:Chd6
|
UTSW |
2 |
160,808,289 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R5215:Chd6
|
UTSW |
2 |
160,791,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5275:Chd6
|
UTSW |
2 |
160,811,283 (GRCm39) |
missense |
probably benign |
|
|
R5405:Chd6
|
UTSW |
2 |
160,807,310 (GRCm39) |
missense |
probably benign |
|
|
R5598:Chd6
|
UTSW |
2 |
160,856,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5693:Chd6
|
UTSW |
2 |
160,807,185 (GRCm39) |
missense |
probably benign |
|
|
R5697:Chd6
|
UTSW |
2 |
160,859,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5715:Chd6
|
UTSW |
2 |
160,791,798 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5759:Chd6
|
UTSW |
2 |
160,825,682 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5761:Chd6
|
UTSW |
2 |
160,798,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5761:Chd6
|
UTSW |
2 |
160,798,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5954:Chd6
|
UTSW |
2 |
160,807,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6025:Chd6
|
UTSW |
2 |
160,807,502 (GRCm39) |
missense |
probably benign |
|
|
R6104:Chd6
|
UTSW |
2 |
160,856,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6247:Chd6
|
UTSW |
2 |
160,791,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6393:Chd6
|
UTSW |
2 |
160,821,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6452:Chd6
|
UTSW |
2 |
160,807,418 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6468:Chd6
|
UTSW |
2 |
160,854,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6784:Chd6
|
UTSW |
2 |
160,808,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6803:Chd6
|
UTSW |
2 |
160,802,279 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R6869:Chd6
|
UTSW |
2 |
160,807,650 (GRCm39) |
missense |
probably benign |
|
|
R6895:Chd6
|
UTSW |
2 |
160,830,260 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6925:Chd6
|
UTSW |
2 |
160,855,047 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7061:Chd6
|
UTSW |
2 |
160,867,885 (GRCm39) |
nonsense |
probably null |
|
|
R7064:Chd6
|
UTSW |
2 |
160,791,983 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7248:Chd6
|
UTSW |
2 |
160,803,199 (GRCm39) |
nonsense |
probably null |
|
|
R7287:Chd6
|
UTSW |
2 |
160,850,312 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7431:Chd6
|
UTSW |
2 |
160,868,248 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7486:Chd6
|
UTSW |
2 |
160,791,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7509:Chd6
|
UTSW |
2 |
160,855,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7699:Chd6
|
UTSW |
2 |
160,867,863 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7748:Chd6
|
UTSW |
2 |
160,808,539 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7785:Chd6
|
UTSW |
2 |
160,812,095 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8002:Chd6
|
UTSW |
2 |
160,832,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8261:Chd6
|
UTSW |
2 |
160,799,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8317:Chd6
|
UTSW |
2 |
160,832,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8388:Chd6
|
UTSW |
2 |
160,861,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8865:Chd6
|
UTSW |
2 |
160,862,989 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8867:Chd6
|
UTSW |
2 |
160,862,989 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8996:Chd6
|
UTSW |
2 |
160,823,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9091:Chd6
|
UTSW |
2 |
160,871,793 (GRCm39) |
nonsense |
probably null |
|
|
R9270:Chd6
|
UTSW |
2 |
160,871,793 (GRCm39) |
nonsense |
probably null |
|
|
R9310:Chd6
|
UTSW |
2 |
160,881,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9367:Chd6
|
UTSW |
2 |
160,871,784 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9438:Chd6
|
UTSW |
2 |
160,799,078 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9756:Chd6
|
UTSW |
2 |
160,802,259 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Chd6
|
UTSW |
2 |
160,808,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTTGGCACCAACACACTGCCTC -3'
(R):5'- GCCAGCCCTATGCTTTGTCTTTGAG -3'
Sequencing Primer
(F):5'- ACTGCCTCAGTCATGGAACTTG -3'
(R):5'- CAGTGTTACAAGCTAAACATCTCGG -3'
|
| Posted On |
2014-01-15 |
Incidental Mutation