Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01650:Vmn1r62'

102802

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r62

Ensembl Gene

ENSMUSG00000092579

Gene Name

vomeronasal 1 receptor 62

Synonyms

V1rd2, V1rd8, V3R2

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.043) question?

Stock #

IGL01650

Quality Score

Status

Chromosome

Chromosomal Location

5674627-5676383 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 5676025 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 235 (V235A)

Ref Sequence

ENSEMBL: ENSMUSP00000134168 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000173956]

AlphaFold

Q8R2C0

Predicted Effect

probably damaging
Transcript: ENSMUST00000173956
AA Change: V235A

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000134168
Gene: ENSMUSG00000092579
AA Change: V235A

Domain	Start	End	E-Value	Type
Pfam:TAS2R	1	296	2.8e-11	PFAM
Pfam:7tm_1	20	279	3.1e-6	PFAM
Pfam:V1R	31	299	4.2e-18	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 34 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4932438A13Rik	G	A	3: 36,992,673		probably benign	Het
Agbl1	A	G	7: 76,420,319	D281G	probably damaging	Het
Arhgap28	T	C	17: 67,873,132	E236G	probably damaging	Het
Btbd3	A	T	2: 138,284,105	D334V	probably damaging	Het
Cabp4	T	C	19: 4,139,324	E78G	probably benign	Het
Clcn4	T	C	7: 7,284,281		probably benign	Het
Col14a1	A	G	15: 55,406,693	Y600C	unknown	Het
Cpne4	A	G	9: 104,901,511	D167G	probably damaging	Het
Eif3a	T	A	19: 60,773,996	I450F	probably damaging	Het
Enpp2	T	A	15: 54,919,933	Y10F	probably benign	Het
Fam227a	A	T	15: 79,634,073	H339Q	possibly damaging	Het
Far2	C	A	6: 148,173,487	T406K	possibly damaging	Het
Fmo1	A	G	1: 162,833,584	S377P	probably benign	Het
Fsip2	G	A	2: 82,991,086	S5721N	probably benign	Het
Gatb	T	C	3: 85,613,484	I300T	possibly damaging	Het
Gpam	T	C	19: 55,081,700	N375D	probably benign	Het
Gsdma	G	T	11: 98,673,687	D331Y	probably damaging	Het
Kif13b	T	C	14: 64,765,145	V1073A	probably benign	Het
Mfsd4b1	T	A	10: 40,003,119	M261L	probably benign	Het
Nav1	A	T	1: 135,454,760	D1321E	probably damaging	Het
Olfr1312	A	G	2: 112,042,375	I219T	possibly damaging	Het
Olfr592	A	G	7: 103,187,079	I159M	probably benign	Het
Olfr813	T	A	10: 129,857,067	L183Q	probably damaging	Het
Olfr816	A	G	10: 129,911,681	V199A	probably benign	Het
Olfr951	G	T	9: 39,393,956	S55I	probably damaging	Het
Ppp1r10	G	T	17: 35,931,161	R857L	unknown	Het
Prune2	T	A	19: 17,168,292	I2752N	possibly damaging	Het
Pxdn	T	C	12: 30,002,401	I859T	probably benign	Het
Ros1	T	C	10: 52,154,979	D510G	probably damaging	Het
Sema3g	C	A	14: 31,221,787	P208H	probably benign	Het
Smcr8	T	C	11: 60,778,184	F53L	probably damaging	Het
Tnfsf13b	A	T	8: 10,031,411	I219F	probably damaging	Het
Vmn2r44	C	A	7: 8,380,104		probably null	Het
Zkscan7	A	G	9: 122,894,827	D287G	probably benign	Het

Other mutations in Vmn1r62

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01337:Vmn1r62	APN	7	5676145	missense	probably damaging	1.00
IGL02892:Vmn1r62	APN	7	5676203	missense	probably benign
IGL02970:Vmn1r62	APN	7	5675568	missense	possibly damaging	0.64
IGL03282:Vmn1r62	APN	7	5675548	missense	possibly damaging	0.93
R0470:Vmn1r62	UTSW	7	5676067	nonsense	probably null
R1416:Vmn1r62	UTSW	7	5675905	missense	probably damaging	1.00
R2149:Vmn1r62	UTSW	7	5675359	missense	probably benign	0.18
R4093:Vmn1r62	UTSW	7	5675944	missense	probably damaging	0.96
R4596:Vmn1r62	UTSW	7	5675307	start gained	probably benign
R4809:Vmn1r62	UTSW	7	5675867	missense	probably benign	0.41
R5669:Vmn1r62	UTSW	7	5675737	nonsense	probably null
R6262:Vmn1r62	UTSW	7	5675557	missense	probably damaging	1.00
R6312:Vmn1r62	UTSW	7	5676084	missense	possibly damaging	0.82
R6548:Vmn1r62	UTSW	7	5675770	missense	probably damaging	1.00
R7624:Vmn1r62	UTSW	7	5675601	missense	probably benign	0.01
R7710:Vmn1r62	UTSW	7	5675183	start gained	probably benign
R7896:Vmn1r62	UTSW	7	5675610	missense	probably damaging	1.00
R8117:Vmn1r62	UTSW	7	5675727	missense	possibly damaging	0.62
R8673:Vmn1r62	UTSW	7	5675278	start gained	probably benign
R8714:Vmn1r62	UTSW	7	5675630	nonsense	probably null
R8962:Vmn1r62	UTSW	7	5675602	missense	probably damaging	0.99
R9133:Vmn1r62	UTSW	7	5676063	missense	probably benign	0.01
R9246:Vmn1r62	UTSW	7	5675629	missense	probably damaging	1.00
R9360:Vmn1r62	UTSW	7	5675953	missense	probably damaging	0.99
RF007:Vmn1r62	UTSW	7	5675670	missense	probably benign	0.00

Posted On

2014-01-21