Incidental Mutation 'IGL01653:Zfp1007'
| ID |
102896 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp1007
|
| Ensembl Gene |
ENSMUSG00000072763 |
| Gene Name |
zinc finger protein 1007 |
| Synonyms |
5430403G16Rik, ENSMUSG00000072763 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.105)
|
| Stock # |
IGL01653
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
5 |
| Chromosomal Location |
109822409-109838700 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
A to C
at 109825182 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Stop codon
at position 89
(Y89*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000090395
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000092720]
|
| AlphaFold |
D3Z5L4 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000092720
AA Change: Y89*
|
| SMART Domains |
Protein: ENSMUSP00000090395
Gene: ENSMUSG00000072763
AA Change: Y89*
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
4 |
60 |
2.47e-14 |
SMART |
|
ZnF_C2H2
|
131 |
153 |
3.39e-3 |
SMART |
|
ZnF_C2H2
|
159 |
181 |
3.95e-4 |
SMART |
|
ZnF_C2H2
|
187 |
209 |
3.95e-4 |
SMART |
|
ZnF_C2H2
|
215 |
237 |
1.12e-3 |
SMART |
|
ZnF_C2H2
|
243 |
265 |
4.01e-5 |
SMART |
|
ZnF_C2H2
|
271 |
293 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
299 |
321 |
2.61e-4 |
SMART |
|
ZnF_C2H2
|
327 |
349 |
1.36e-2 |
SMART |
|
ZnF_C2H2
|
355 |
377 |
7.37e-4 |
SMART |
|
ZnF_C2H2
|
383 |
405 |
1.3e-4 |
SMART |
|
ZnF_C2H2
|
411 |
433 |
3.69e-4 |
SMART |
|
ZnF_C2H2
|
439 |
461 |
4.3e-5 |
SMART |
|
ZnF_C2H2
|
467 |
489 |
2.57e-3 |
SMART |
|
ZnF_C2H2
|
495 |
517 |
2.61e-4 |
SMART |
|
ZnF_C2H2
|
523 |
545 |
2.05e-2 |
SMART |
|
ZnF_C2H2
|
551 |
573 |
5.59e-4 |
SMART |
|
ZnF_C2H2
|
579 |
601 |
1.58e-3 |
SMART |
|
ZnF_C2H2
|
607 |
629 |
9.08e-4 |
SMART |
|
ZnF_C2H2
|
635 |
657 |
3.44e-4 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 31 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933421I07Rik |
T |
C |
7: 42,096,398 (GRCm39) |
D119G |
probably damaging |
Het |
| Apol7c |
A |
G |
15: 77,410,500 (GRCm39) |
C149R |
probably damaging |
Het |
| Arfgef1 |
G |
A |
1: 10,230,133 (GRCm39) |
R1235* |
probably null |
Het |
| Bpifb4 |
A |
G |
2: 153,786,703 (GRCm39) |
D285G |
probably damaging |
Het |
| Cep192 |
T |
A |
18: 67,986,043 (GRCm39) |
H1682Q |
possibly damaging |
Het |
| Cerk |
G |
T |
15: 86,033,552 (GRCm39) |
Y290* |
probably null |
Het |
| Cyld |
A |
T |
8: 89,467,998 (GRCm39) |
I544F |
probably damaging |
Het |
| Dcp1a |
T |
C |
14: 30,227,528 (GRCm39) |
S134P |
possibly damaging |
Het |
| Epha6 |
A |
C |
16: 59,659,666 (GRCm39) |
N817K |
probably benign |
Het |
| Ephb4 |
A |
G |
5: 137,364,003 (GRCm39) |
|
probably benign |
Het |
| Fcgr3 |
A |
T |
1: 170,886,849 (GRCm39) |
L25Q |
probably damaging |
Het |
| Heatr3 |
A |
G |
8: 88,871,245 (GRCm39) |
I83V |
probably benign |
Het |
| Hormad1 |
T |
A |
3: 95,485,608 (GRCm39) |
N265K |
possibly damaging |
Het |
| Kpna1 |
A |
G |
16: 35,840,562 (GRCm39) |
T201A |
probably benign |
Het |
| Krt6b |
T |
A |
15: 101,587,549 (GRCm39) |
T182S |
probably damaging |
Het |
| Macc1 |
A |
G |
12: 119,414,088 (GRCm39) |
K755E |
probably damaging |
Het |
| Med12l |
C |
T |
3: 59,169,314 (GRCm39) |
T1568M |
probably damaging |
Het |
| Muc4 |
G |
T |
16: 32,581,722 (GRCm39) |
|
probably null |
Het |
| Myt1l |
T |
C |
12: 29,960,770 (GRCm39) |
S1028P |
unknown |
Het |
| Nhlrc2 |
C |
T |
19: 56,559,282 (GRCm39) |
R256C |
probably benign |
Het |
| Or4c123 |
T |
A |
2: 89,127,471 (GRCm39) |
T48S |
probably benign |
Het |
| Or5a3 |
G |
A |
19: 12,399,736 (GRCm39) |
R21H |
probably benign |
Het |
| Pfkfb4 |
G |
A |
9: 108,828,202 (GRCm39) |
R79H |
probably damaging |
Het |
| Piezo2 |
T |
C |
18: 63,315,904 (GRCm39) |
|
probably benign |
Het |
| Pramel5 |
C |
T |
4: 144,000,429 (GRCm39) |
R49H |
probably benign |
Het |
| Ralgapb |
T |
A |
2: 158,304,079 (GRCm39) |
S613T |
possibly damaging |
Het |
| Ryr1 |
T |
C |
7: 28,778,022 (GRCm39) |
E2158G |
probably damaging |
Het |
| Scgb2b19 |
T |
A |
7: 32,979,153 (GRCm39) |
Y43F |
probably damaging |
Het |
| Slc17a6 |
A |
G |
7: 51,317,770 (GRCm39) |
T468A |
possibly damaging |
Het |
| Slc36a1 |
A |
G |
11: 55,119,147 (GRCm39) |
D374G |
possibly damaging |
Het |
| Wdtc1 |
T |
C |
4: 133,022,543 (GRCm39) |
D601G |
probably damaging |
Het |
|
| Other mutations in Zfp1007 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02547:Zfp1007
|
APN |
5 |
109,826,628 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02589:Zfp1007
|
APN |
5 |
109,826,386 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
BB007:Zfp1007
|
UTSW |
5 |
109,823,622 (GRCm39) |
nonsense |
probably null |
|
|
BB017:Zfp1007
|
UTSW |
5 |
109,823,622 (GRCm39) |
nonsense |
probably null |
|
|
R0363:Zfp1007
|
UTSW |
5 |
109,824,754 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0628:Zfp1007
|
UTSW |
5 |
109,826,442 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R2858:Zfp1007
|
UTSW |
5 |
109,823,819 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4914:Zfp1007
|
UTSW |
5 |
109,826,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4945:Zfp1007
|
UTSW |
5 |
109,824,941 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R5444:Zfp1007
|
UTSW |
5 |
109,823,502 (GRCm39) |
nonsense |
probably null |
|
|
R6000:Zfp1007
|
UTSW |
5 |
109,824,730 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6258:Zfp1007
|
UTSW |
5 |
109,824,433 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6389:Zfp1007
|
UTSW |
5 |
109,823,885 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6945:Zfp1007
|
UTSW |
5 |
109,824,711 (GRCm39) |
missense |
probably benign |
0.25 |
|
R7225:Zfp1007
|
UTSW |
5 |
109,825,015 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7581:Zfp1007
|
UTSW |
5 |
109,838,654 (GRCm39) |
start gained |
probably benign |
|
|
R7810:Zfp1007
|
UTSW |
5 |
109,825,170 (GRCm39) |
nonsense |
probably null |
|
|
R7930:Zfp1007
|
UTSW |
5 |
109,823,622 (GRCm39) |
nonsense |
probably null |
|
|
R8821:Zfp1007
|
UTSW |
5 |
109,824,174 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8825:Zfp1007
|
UTSW |
5 |
109,826,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8831:Zfp1007
|
UTSW |
5 |
109,824,174 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9179:Zfp1007
|
UTSW |
5 |
109,823,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9429:Zfp1007
|
UTSW |
5 |
109,824,334 (GRCm39) |
nonsense |
probably null |
|
|
R9486:Zfp1007
|
UTSW |
5 |
109,824,062 (GRCm39) |
nonsense |
probably null |
|
|
R9496:Zfp1007
|
UTSW |
5 |
109,823,924 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9525:Zfp1007
|
UTSW |
5 |
109,824,846 (GRCm39) |
missense |
|
|
|
| Posted On |
2014-01-21 |
Incidental Mutation