Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01656:Tas2r116'

103035

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tas2r116

Ensembl Gene

ENSMUSG00000030194

Gene Name

taste receptor, type 2, member 116

Synonyms

mGR16, TRB1, Tas2r7, Tas2r16, T2R16, mt2r56, Tas2r14, TRB4

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL01656

Quality Score

Status

Chromosome

Chromosomal Location

132832401-132833318 bp(+) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to C at 132832396 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000032315 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000032315]

AlphaFold

Q7M713

Predicted Effect

probably benign
Transcript: ENSMUST00000032315

SMART Domains

Protein: ENSMUSP00000032315
Gene: ENSMUSG00000030194

Domain	Start	End	E-Value	Type
Pfam:TAS2R	1	300	2.8e-89	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 46 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acrbp	A	C	6: 125,030,675 (GRCm39)	E232A	possibly damaging	Het
Anapc11	T	A	11: 120,490,173 (GRCm39)	F30I	possibly damaging	Het
Ap5z1	A	G	5: 142,456,069 (GRCm39)	D318G	probably benign	Het
Cfap43	T	C	19: 47,740,339 (GRCm39)	E1278G	possibly damaging	Het
Cylc1	A	G	X: 110,167,485 (GRCm39)	T589A	probably benign	Het
Dcaf15	T	C	8: 84,824,617 (GRCm39)	I527V	probably benign	Het
Ddhd2	C	T	8: 26,217,739 (GRCm39)	V713I	probably benign	Het
Edc4	T	C	8: 106,613,009 (GRCm39)	V283A	possibly damaging	Het
Elf5	A	G	2: 103,273,206 (GRCm39)		probably benign	Het
Flnb	C	T	14: 7,902,010 (GRCm38)		probably benign	Het
Flnc	C	T	6: 29,443,507 (GRCm39)		probably benign	Het
Fstl4	T	C	11: 52,891,201 (GRCm39)	L113P	probably damaging	Het
Gemin4	C	T	11: 76,104,636 (GRCm39)	V42M	probably damaging	Het
Gm10076	A	G	14: 105,919,354 (GRCm39)		noncoding transcript	Het
Grina	A	G	15: 76,132,501 (GRCm39)	Y116C	probably damaging	Het
Hectd4	T	A	5: 121,460,763 (GRCm39)	L914H	probably damaging	Het
Il17re	T	C	6: 113,439,934 (GRCm39)		probably benign	Het
Ivl	G	A	3: 92,478,962 (GRCm39)	Q368*	probably null	Het
Kbtbd8	A	G	6: 95,095,657 (GRCm39)	H73R	probably benign	Het
Krt90	T	A	15: 101,463,878 (GRCm39)	Q392L	probably damaging	Het
Magea3	A	T	X: 153,732,137 (GRCm39)	M122K	probably damaging	Het
Mapk8ip3	T	C	17: 25,137,003 (GRCm39)	D237G	probably damaging	Het
Nln	T	C	13: 104,198,249 (GRCm39)		probably null	Het
Nlrp4d	T	C	7: 10,098,074 (GRCm39)	Y853C	noncoding transcript	Het
Nol11	T	C	11: 107,079,998 (GRCm39)	D29G	probably benign	Het
Nr3c2	C	T	8: 77,914,166 (GRCm39)	L791F	probably damaging	Het
Nup50l	A	G	6: 96,142,675 (GRCm39)	V123A	possibly damaging	Het
Olfm3	T	C	3: 114,916,282 (GRCm39)	Y385H	probably damaging	Het
Or14j5	C	T	17: 38,162,029 (GRCm39)	P182L	possibly damaging	Het
Or51a8	A	G	7: 102,550,472 (GRCm39)	I299M	possibly damaging	Het
Or5b119	G	A	19: 13,457,454 (GRCm39)	A36V	probably benign	Het
Pklr	G	T	3: 89,052,302 (GRCm39)	G505C	probably damaging	Het
Plxna2	A	G	1: 194,472,469 (GRCm39)	E1071G	possibly damaging	Het
Prkcq	G	T	2: 11,231,766 (GRCm39)	A30S	probably damaging	Het
Rilpl1	A	G	5: 124,641,712 (GRCm39)	F104L	probably damaging	Het
Rsph6a	C	T	7: 18,788,770 (GRCm39)	T34I	probably benign	Het
Sec23ip	C	T	7: 128,351,969 (GRCm39)	P12L	probably damaging	Het
Slc25a21	A	C	12: 56,785,280 (GRCm39)	V199G	probably damaging	Het
Smc1b	T	C	15: 84,998,977 (GRCm39)	E483G	probably damaging	Het
Sucnr1	T	C	3: 59,993,832 (GRCm39)	M120T	possibly damaging	Het
Tbrg4	T	A	11: 6,568,522 (GRCm39)	Q419L	possibly damaging	Het
Tc2n	A	G	12: 101,615,348 (GRCm39)		probably benign	Het
Tgfbr2	A	C	9: 115,938,737 (GRCm39)	S388R	probably damaging	Het
Vmn2r1	A	G	3: 63,989,274 (GRCm39)	E71G	probably damaging	Het
Xpc	A	T	6: 91,482,449 (GRCm39)	I176K	probably damaging	Het
Xylt1	G	T	7: 117,148,228 (GRCm39)	R264L	probably damaging	Het

Other mutations in Tas2r116

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01305:Tas2r116	APN	6	132,832,406 (GRCm39)	missense	probably benign	0.02
IGL01970:Tas2r116	APN	6	132,832,632 (GRCm39)	missense	probably benign	0.07
ANU22:Tas2r116	UTSW	6	132,832,406 (GRCm39)	missense	probably benign	0.02
R0490:Tas2r116	UTSW	6	132,832,984 (GRCm39)	missense	probably benign	0.02
R2422:Tas2r116	UTSW	6	132,832,557 (GRCm39)	missense	possibly damaging	0.88
R4013:Tas2r116	UTSW	6	132,833,230 (GRCm39)	missense	probably damaging	1.00
R4516:Tas2r116	UTSW	6	132,833,113 (GRCm39)	missense	probably damaging	1.00
R4745:Tas2r116	UTSW	6	132,832,668 (GRCm39)	missense	probably benign	0.14
R4842:Tas2r116	UTSW	6	132,832,660 (GRCm39)	missense	probably benign	0.00
R7723:Tas2r116	UTSW	6	132,832,867 (GRCm39)	missense	probably benign	0.25
R8439:Tas2r116	UTSW	6	132,832,540 (GRCm39)	missense	probably damaging	0.99
R8551:Tas2r116	UTSW	6	132,832,993 (GRCm39)	missense	probably benign	0.01
R9009:Tas2r116	UTSW	6	132,832,963 (GRCm39)	missense	probably damaging	1.00
R9573:Tas2r116	UTSW	6	132,833,140 (GRCm39)	missense	probably benign	0.04
Z1088:Tas2r116	UTSW	6	132,832,911 (GRCm39)	missense	probably benign	0.01

Posted On

2014-01-21