Incidental Mutation 'IGL01667:Clec4a3'
ID103353
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Clec4a3
Ensembl Gene ENSMUSG00000043832
Gene NameC-type lectin domain family 4, member a3
Synonyms3110037K17Rik, mDcir3
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01667
Quality Score
Status
Chromosome6
Chromosomal Location122952515-122969875 bp(+) (GRCm38)
Type of Mutationutr 5 prime
DNA Base Change (assembly) A to C at 122952860 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000144856 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000088468] [ENSMUST00000117173] [ENSMUST00000204427]
Predicted Effect probably benign
Transcript: ENSMUST00000088468
SMART Domains Protein: ENSMUSP00000085816
Gene: ENSMUSG00000043832

DomainStartEndE-ValueType
transmembrane domain 45 67 N/A INTRINSIC
CLECT 107 231 1.97e-32 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000117173
SMART Domains Protein: ENSMUSP00000112716
Gene: ENSMUSG00000043832

DomainStartEndE-ValueType
transmembrane domain 45 67 N/A INTRINSIC
CLECT 107 231 1.97e-32 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000204427
SMART Domains Protein: ENSMUSP00000144856
Gene: ENSMUSG00000043832

DomainStartEndE-ValueType
transmembrane domain 45 67 N/A INTRINSIC
SCOP:d1e87a_ 71 109 1e-8 SMART
Blast:CLECT 73 109 2e-20 BLAST
PDB:3VYK|A 73 109 7e-13 PDB
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Akap13 A G 7: 75,570,019 T57A probably damaging Het
Akna G T 4: 63,379,159 T886N probably benign Het
Aqp9 A G 9: 71,138,213 V38A probably benign Het
Awat2 C T X: 100,404,254 G124D probably damaging Het
Camsap1 A G 2: 25,945,281 probably benign Het
Catsperg2 T C 7: 29,710,133 Y545C probably damaging Het
Cldn23 A G 8: 35,825,920 F138S possibly damaging Het
Dlgap3 C A 4: 127,233,897 T786K probably benign Het
Dnah2 A C 11: 69,544,395 S50A probably benign Het
Dnah2 A T 11: 69,520,941 I285N probably damaging Het
Dnah7a A G 1: 53,547,292 Y1467H probably damaging Het
Fgf22 C T 10: 79,756,754 P115L probably damaging Het
Fzd2 G T 11: 102,605,782 V351L possibly damaging Het
Gapdhs T A 7: 30,736,637 E174V possibly damaging Het
Gjc2 A C 11: 59,177,518 I46S probably damaging Het
Gm5581 T C 6: 131,167,772 noncoding transcript Het
Krt2 C A 15: 101,816,330 V282L possibly damaging Het
Myh15 G A 16: 49,195,579 V1873M probably benign Het
Myo1b T C 1: 51,760,377 T931A probably damaging Het
Myo6 A T 9: 80,289,893 K965N unknown Het
Olfr1441 T C 19: 12,422,756 V149A probably benign Het
Pcnx3 T C 19: 5,686,630 R160G probably benign Het
Slc22a16 T C 10: 40,585,018 I272T probably damaging Het
Slc35b4 A G 6: 34,167,675 Y82H possibly damaging Het
Spdya T C 17: 71,556,259 M1T probably null Het
St6gal1 A G 16: 23,321,424 N115S probably benign Het
Tbc1d12 A T 19: 38,914,300 probably benign Het
Tfrc A G 16: 32,624,443 probably benign Het
Trip11 A C 12: 101,878,862 F1539C probably damaging Het
Ttn A T 2: 76,781,078 I15624N possibly damaging Het
Vmn1r169 A T 7: 23,577,800 M206L probably benign Het
Zfp362 A G 4: 128,787,109 L141P probably damaging Het
Zfp692 A G 11: 58,311,553 H378R probably damaging Het
Zfp799 T C 17: 32,821,820 Q52R possibly damaging Het
Other mutations in Clec4a3
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02210:Clec4a3 APN 6 122954108 missense probably damaging 0.98
IGL02874:Clec4a3 APN 6 122967560 missense probably benign 0.16
IGL02983:Clec4a3 APN 6 122967567 critical splice donor site probably null
R0035:Clec4a3 UTSW 6 122967549 missense probably damaging 1.00
R0035:Clec4a3 UTSW 6 122967549 missense probably damaging 1.00
R0334:Clec4a3 UTSW 6 122969370 missense possibly damaging 0.81
R0671:Clec4a3 UTSW 6 122954034 critical splice acceptor site probably null
R1508:Clec4a3 UTSW 6 122967508 missense probably benign 0.05
R1739:Clec4a3 UTSW 6 122954041 nonsense probably null
R3547:Clec4a3 UTSW 6 122964280 missense probably damaging 1.00
R5836:Clec4a3 UTSW 6 122952902 missense possibly damaging 0.66
R5953:Clec4a3 UTSW 6 122969492 missense probably benign 0.12
R7178:Clec4a3 UTSW 6 122964292 missense probably benign 0.02
R7664:Clec4a3 UTSW 6 122966422 missense probably benign 0.03
R7763:Clec4a3 UTSW 6 122964340 missense probably benign 0.01
Posted On2014-01-21