Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01678:Vmn1r212'

103691

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r212

Ensembl Gene

ENSMUSG00000071490

Gene Name

vomeronasal 1 receptor 212

Synonyms

V1rh18

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.075) question?

Stock #

IGL01678

Quality Score

Status

Chromosome

Chromosomal Location

23067212-23068375 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 23068081 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Aspartic acid at position 84 (V84D)

Ref Sequence

ENSEMBL: ENSMUSP00000093655 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000095960]

AlphaFold

Q8R268

Predicted Effect

probably damaging
Transcript: ENSMUST00000095960
AA Change: V84D

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000093655
Gene: ENSMUSG00000071490
AA Change: V84D

Domain	Start	End	E-Value	Type
Pfam:TAS2R	2	292	1.2e-7	PFAM
Pfam:V1R	34	297	5.4e-36	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000158990

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000226672

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000226881

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 34 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aadacl4fm5	A	T	4: 144,504,443 (GRCm39)	M236K	probably benign	Het
Abcc1	T	A	16: 14,222,883 (GRCm39)	M186K	probably null	Het
Adamts3	T	C	5: 89,855,715 (GRCm39)	N385S	probably damaging	Het
Adamts6	T	C	13: 104,450,196 (GRCm39)	V299A	probably damaging	Het
Angel1	T	C	12: 86,763,800 (GRCm39)	E500G	probably benign	Het
Car9	T	C	4: 43,512,941 (GRCm39)		probably benign	Het
Colec11	A	G	12: 28,644,867 (GRCm39)	F209S	probably damaging	Het
Dnaaf10	T	C	11: 17,182,790 (GRCm39)	V317A	probably benign	Het
Dock10	A	G	1: 80,521,069 (GRCm39)	Y1179H	probably damaging	Het
Ece1	T	A	4: 137,690,044 (GRCm39)	W697R	probably damaging	Het
Eml2	T	A	7: 18,920,047 (GRCm39)	M117K	probably benign	Het
Flii	G	T	11: 60,607,672 (GRCm39)		probably benign	Het
Frmpd1	T	A	4: 45,243,717 (GRCm39)	D63E	probably damaging	Het
Ftmt	A	T	18: 52,465,206 (GRCm39)	H174L	probably damaging	Het
Gpr37l1	A	G	1: 135,094,791 (GRCm39)	V151A	probably damaging	Het
Inppl1	T	C	7: 101,481,803 (GRCm39)	T180A	probably benign	Het
Klhdc4	T	C	8: 122,523,677 (GRCm39)	D513G	possibly damaging	Het
Klrb1a	A	G	6: 128,595,411 (GRCm39)		probably benign	Het
Nit1	A	G	1: 171,170,262 (GRCm39)	V270A	probably damaging	Het
Or6c5	A	C	10: 129,074,537 (GRCm39)	D173A	possibly damaging	Het
Phox2b	T	A	5: 67,256,262 (GRCm39)	Y8F	probably damaging	Het
Psg20	T	A	7: 18,414,795 (GRCm39)	S364C	probably damaging	Het
Rab38	T	A	7: 88,079,740 (GRCm39)	V44E	probably damaging	Het
Rapgef4	T	C	2: 72,072,569 (GRCm39)		probably benign	Het
Ror1	C	T	4: 100,283,165 (GRCm39)	P410L	possibly damaging	Het
Rptn	A	G	3: 93,304,118 (GRCm39)	N484D	probably benign	Het
Sirpb1a	G	T	3: 15,476,370 (GRCm39)	S142R	probably damaging	Het
Smox	G	A	2: 131,353,979 (GRCm39)	R17H	possibly damaging	Het
Top6bl	T	A	19: 4,722,193 (GRCm39)	I76L	possibly damaging	Het
Trpm7	A	T	2: 126,658,719 (GRCm39)	C1146S	probably damaging	Het
Upf3a	C	T	8: 13,841,930 (GRCm39)	A155V	probably benign	Het
Vmn2r40	T	C	7: 8,923,105 (GRCm39)	N419D	probably damaging	Het
Zfp143	C	A	7: 109,679,558 (GRCm39)		probably benign	Het
Zmat4	T	A	8: 24,392,064 (GRCm39)	C7S	probably damaging	Het

Other mutations in Vmn1r212

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01131:Vmn1r212	APN	13	23,067,329 (GRCm39)	missense	unknown
R0798:Vmn1r212	UTSW	13	23,067,868 (GRCm39)	missense	probably damaging	1.00
R1237:Vmn1r212	UTSW	13	23,067,638 (GRCm39)	nonsense	probably null
R1331:Vmn1r212	UTSW	13	23,067,562 (GRCm39)	missense	probably benign	0.33
R2064:Vmn1r212	UTSW	13	23,068,285 (GRCm39)	missense	probably benign	0.28
R2356:Vmn1r212	UTSW	13	23,068,120 (GRCm39)	nonsense	probably null
R2846:Vmn1r212	UTSW	13	23,068,262 (GRCm39)	missense	probably damaging	0.99
R3896:Vmn1r212	UTSW	13	23,068,067 (GRCm39)	missense	probably benign	0.00
R3937:Vmn1r212	UTSW	13	23,067,358 (GRCm39)	missense	unknown
R4722:Vmn1r212	UTSW	13	23,068,078 (GRCm39)	missense	probably damaging	1.00
R5233:Vmn1r212	UTSW	13	23,067,304 (GRCm39)	missense	unknown
R6043:Vmn1r212	UTSW	13	23,068,258 (GRCm39)	missense	probably damaging	0.98
R7199:Vmn1r212	UTSW	13	23,067,731 (GRCm39)	missense	probably benign	0.12
R7413:Vmn1r212	UTSW	13	23,067,718 (GRCm39)	missense	probably damaging	1.00
R7840:Vmn1r212	UTSW	13	23,067,323 (GRCm39)	missense	unknown
R8054:Vmn1r212	UTSW	13	23,067,935 (GRCm39)	missense	probably benign	0.25
R8844:Vmn1r212	UTSW	13	23,067,526 (GRCm39)	missense	probably benign	0.00
R8929:Vmn1r212	UTSW	13	23,067,494 (GRCm39)	missense	possibly damaging	0.69
R9538:Vmn1r212	UTSW	13	23,067,451 (GRCm39)	missense	probably benign	0.03
R9612:Vmn1r212	UTSW	13	23,067,443 (GRCm39)	missense	possibly damaging	0.96
Z1088:Vmn1r212	UTSW	13	23,067,932 (GRCm39)	missense	probably damaging	1.00

Posted On

2014-01-21