Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01682:Gm10228'

103845

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm10228

Ensembl Gene

ENSMUSG00000068074

Gene Name

predicted gene 10228

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.138) question?

Stock #

IGL01682

Quality Score

Status

Chromosome

Chromosomal Location

88837811-88838360 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 88838073 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Phenylalanine at position 77 (Y77F)

Ref Sequence

ENSEMBL: ENSMUSP00000086506 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000089105]

AlphaFold

no structure available at present

Predicted Effect

unknown
Transcript: ENSMUST00000089105
AA Change: Y77F

SMART Domains

Protein: ENSMUSP00000086506
Gene: ENSMUSG00000068074
AA Change: Y77F

Domain	Start	End	E-Value	Type
Pfam:KRTAP	1	62	2.4e-8	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 30 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Agmo	T	C	12: 37,407,626 (GRCm39)		probably benign	Het
Atp2c1	C	T	9: 105,330,041 (GRCm39)	G93D	probably damaging	Het
C2cd6	T	G	1: 59,101,660 (GRCm39)	Y333S	probably damaging	Het
Cacna1a	A	G	8: 85,263,067 (GRCm39)	E414G	possibly damaging	Het
Capn10	C	A	1: 92,868,106 (GRCm39)	T191K	probably benign	Het
Cd226	A	T	18: 89,287,187 (GRCm39)	R328S	probably damaging	Het
Cdk10	A	G	8: 123,954,397 (GRCm39)		probably null	Het
Cyp4a31	T	A	4: 115,435,228 (GRCm39)	V486D	probably damaging	Het
Dgke	A	T	11: 88,943,267 (GRCm39)	L241I	probably damaging	Het
Dnah6	G	T	6: 73,052,785 (GRCm39)	A2965E	probably damaging	Het
Fbn2	A	T	18: 58,205,743 (GRCm39)	C1112S	probably damaging	Het
Gng3	T	C	19: 8,815,944 (GRCm39)	I25V	probably benign	Het
Gramd2a	A	G	9: 59,619,393 (GRCm39)	I61M	possibly damaging	Het
Hcar2	T	C	5: 124,002,582 (GRCm39)	N307S	probably benign	Het
Iars1	G	A	13: 49,863,134 (GRCm39)	E529K	probably damaging	Het
Ilvbl	C	T	10: 78,412,941 (GRCm39)		probably benign	Het
Itprid2	A	G	2: 79,465,981 (GRCm39)	Q33R	probably damaging	Het
Lrp1	T	C	10: 127,410,847 (GRCm39)	K1447R	probably benign	Het
Mmp20	A	G	9: 7,671,376 (GRCm39)	D426G	probably benign	Het
Muc4	G	A	16: 32,754,086 (GRCm38)	G1321R	probably benign	Het
Or4f4b	G	A	2: 111,314,188 (GRCm39)	G138S	probably damaging	Het
Or51f2	C	T	7: 102,526,440 (GRCm39)	L38F	probably benign	Het
Pip4k2a	A	G	2: 19,002,779 (GRCm39)	S10P	probably benign	Het
Pth1r	A	T	9: 110,552,774 (GRCm39)		probably null	Het
Rprd1b	T	C	2: 157,892,080 (GRCm39)	I201T	probably damaging	Het
Rsbn1	A	G	3: 103,869,696 (GRCm39)	N719S	probably benign	Het
Sorcs1	C	T	19: 50,169,944 (GRCm39)	G939E	probably benign	Het
St8sia5	A	G	18: 77,336,196 (GRCm39)	K210E	probably damaging	Het
Trav3-1	G	A	14: 52,818,649 (GRCm39)	V108M	probably benign	Het
Washc4	T	C	10: 83,416,170 (GRCm39)	I820T	possibly damaging	Het

Other mutations in Gm10228

Allele	Source	Chr	Coord	Type	Predicted Effect
R1946:Gm10228	UTSW	16	88,838,241 (GRCm39)	missense	unknown
R7431:Gm10228	UTSW	16	88,838,101 (GRCm39)	missense	unknown
R7763:Gm10228	UTSW	16	88,838,187 (GRCm39)	missense	unknown
R9041:Gm10228	UTSW	16	88,838,113 (GRCm39)	missense	unknown

Posted On

2014-01-21