Incidental Mutation 'IGL01688:Mzt2'
ID104043
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Mzt2
Ensembl Gene ENSMUSG00000022671
Gene Namemitotic spindle organizing protein 2
SynonymsFam128b, 2610001E06Rik, 2410018G20Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.116) question?
Stock #IGL01688
Quality Score
Status
Chromosome16
Chromosomal Location15848441-15863369 bp(-) (GRCm38)
Type of Mutationstart gained
DNA Base Change (assembly) T to C at 15862929 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000155739 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000023351] [ENSMUST00000117136] [ENSMUST00000229680]
Predicted Effect probably benign
Transcript: ENSMUST00000023351
SMART Domains Protein: ENSMUSP00000023351
Gene: ENSMUSG00000022671

DomainStartEndE-ValueType
Pfam:MOZART2 1 99 1.4e-38 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000117136
SMART Domains Protein: ENSMUSP00000113832
Gene: ENSMUSG00000022671

DomainStartEndE-ValueType
Pfam:MOZART2 11 98 4.5e-44 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000137864
Predicted Effect probably benign
Transcript: ENSMUST00000229680
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 44 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700113H08Rik T C 10: 87,165,123 L59P probably damaging Het
Ccin A T 4: 43,984,985 E464V possibly damaging Het
Cfap58 A G 19: 47,974,567 D472G probably benign Het
Col28a1 C T 6: 7,998,517 E1131K probably damaging Het
Cpne2 A G 8: 94,554,753 T196A possibly damaging Het
Cul4a A T 8: 13,146,571 R742* probably null Het
Cyp21a1 T A 17: 34,802,220 I370F probably damaging Het
Ddx51 T C 5: 110,655,647 F332L probably benign Het
Gm8232 A G 14: 44,433,722 D29G unknown Het
Got1 A G 19: 43,524,336 probably null Het
Gpat4 A G 8: 23,181,845 I58T probably benign Het
Hdac3 T A 18: 37,954,879 D12V possibly damaging Het
Helb T C 10: 120,108,980 H217R probably damaging Het
Hpf1 A T 8: 60,896,796 I153L probably benign Het
Lgsn G A 1: 31,204,405 D523N probably damaging Het
Lrrc63 A G 14: 75,084,982 S561P possibly damaging Het
Myh6 G A 14: 54,963,960 T94I possibly damaging Het
Ndufb5 T A 3: 32,746,464 L62* probably null Het
Nek1 A T 8: 61,105,597 R970* probably null Het
Nepro T C 16: 44,736,006 L509P probably damaging Het
Pank1 T A 19: 34,840,852 I96F probably damaging Het
Parp11 C A 6: 127,471,606 T62K probably benign Het
Pla2g2e T A 4: 138,879,470 probably benign Het
Plekha5 T A 6: 140,569,389 Y207N probably damaging Het
Pomt2 T A 12: 87,147,520 I37F probably benign Het
Prl6a1 T A 13: 27,317,986 V117E probably damaging Het
Prmt3 T A 7: 49,848,732 probably null Het
Rcor3 T A 1: 192,123,600 E20V probably damaging Het
Rere A G 4: 150,618,436 D1449G probably damaging Het
Ric1 T C 19: 29,577,614 V376A probably benign Het
Rims1 G A 1: 22,397,540 T873I probably benign Het
Rras2 T C 7: 114,060,397 D44G probably damaging Het
Sbk2 C T 7: 4,957,717 probably benign Het
Slit1 A G 19: 41,729,106 I73T probably damaging Het
Spice1 T A 16: 44,384,710 M793K probably benign Het
Suco T C 1: 161,863,911 probably null Het
Tarbp1 A T 8: 126,447,551 W839R probably damaging Het
Trpc4 T A 3: 54,266,074 probably benign Het
Tubgcp5 T C 7: 55,815,018 V549A possibly damaging Het
Ubap2 T A 4: 41,226,308 T182S probably benign Het
Wrn A C 8: 33,310,702 probably benign Het
Zc3h15 A G 2: 83,662,192 Y337C probably damaging Het
Zfp292 T A 4: 34,807,855 I1730F possibly damaging Het
Zfp609 A G 9: 65,704,025 V552A probably benign Het
Other mutations in Mzt2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01155:Mzt2 APN 16 15862410 missense possibly damaging 0.57
R1962:Mzt2 UTSW 16 15848679 missense probably damaging 0.99
R2885:Mzt2 UTSW 16 15862916 missense unknown
R6192:Mzt2 UTSW 16 15848687 missense probably benign 0.12
R7560:Mzt2 UTSW 16 15862805 missense possibly damaging 0.86
Posted On2014-01-21